KEGG ENZYME: 1.13.12.13

ENZYME: 1.13.12.13

Entry

EC 1.13.12.13               Enzyme

Name

Oplophorus-luciferin 2-monooxygenase;
Oplophorus luciferase

Class

Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

Sysname

Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating)

Reaction(IUBMB)

Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu [RN:R07128]

Reaction(KEGG)

R07128

Substrate

Oplophorus luciferin [CPD:C15037];
O2 [CPD:C00007]

Product

oxidized Oplophorus luciferin [CPD:C15038];
CO2 [CPD:C00011];
hnu [CPD:C00205]

Comment

The luciferase from the deep sea shrimp Oplophorus gracilirostris is a complex composed of more than one protein. The enzyme's specificity is quite broad, with both coelenterazine and bisdeoxycoelenterazine being good substrates.

History

EC 1.13.12.13 created 2004

Orthology

K21823

oplophorus-luciferin 2-monooxygenase catalytic subunit

Reference

1 [PMID:629957]

Authors

Shimomura O, Masugi T, Johnson FH, Haneda Y

Title

Properties and reaction mechanism of the bioluminescence system of the deep-sea shrimp Oplophorus gracilorostris.

Journal