KEGG   ENZYME: 1.13.12.20
Entry
EC 1.13.12.20               Enzyme                                 
Name
noranthrone monooxygenase;
norsolorinate anthrone oxidase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
Sysname
norsolorinic acid anthrone:oxygen 9-oxidoreductase (norsolorinic acid-forming)
Reaction(IUBMB)
norsolorinic acid anthrone + O2 = norsolorinic acid + H2O [RN:R10224]
Reaction(KEGG)
R10224
Substrate
norsolorinic acid anthrone [CPD:C20453];
O2 [CPD:C00007]
Product
norsolorinic acid [CPD:C20452];
H2O [CPD:C00001]
Comment
Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.
History
EC 1.13.12.20 created 2013
Pathway
ec00254  Aflatoxin biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K17643  noranthrone monooxygenase
Genes
PANPODANSg8557
AORAO090026000010
AFVAFLA_006310
APUUAPUU_20051A APUU_60343A
Reference
1  [PMID:20348292]
  Authors
Ehrlich KC, Li P, Scharfenstein L, Chang PK
  Title
HypC, the anthrone oxidase involved in aflatoxin biosynthesis.
  Journal
Appl Environ Microbiol 76:3374-7 (2010)
DOI:10.1128/AEM.02495-09
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.13.12.20
IUBMB Enzyme Nomenclature: 1.13.12.20
ExPASy - ENZYME nomenclature database: 1.13.12.20
BRENDA, the Enzyme Database: 1.13.12.20

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