Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
BRITE hierarchy

tetracenomycin-F1:oxygen C5-monooxygenase

tetracenomycin F1 + O2 = tetracenomycin D3 + H2O [RN:R06700]

R06700
Reaction

tetracenomycin F1 [CPD:C12367];
O2 [CPD:C00007]

The enzyme is involved in biosynthesis of the anthracycline antibiotic tetracenomycin C by the bacterium Streptomyces glaucescens.

EC 1.13.12.21 created 2013

1  [PMID:8329392]

Shen B, Hutchinson CR

Tetracenomycin F1 monooxygenase: oxidation of a naphthacenone to a naphthacenequinone in the biosynthesis of tetracenomycin C in Streptomyces glaucescens.

Biochemistry 32:6656-63 (1993)
DOI:10.1021/bi00077a019