KEGG ENZYME: 1.13.12.6

ENZYME: 1.13.12.6

Entry

EC 1.13.12.6                Enzyme

Name

Cypridina-luciferin 2-monooxygenase;
Cypridina-type luciferase;
luciferase (Cypridina luciferin);
Cypridina luciferase

Class

Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

Sysname

Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)

Reaction(IUBMB)

Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + hnu [RN:R04063]

Reaction(KEGG)

R04063

Substrate

Cypridina luciferin [CPD:C02825];
O2 [CPD:C00007]

Product

oxidized Cypridina luciferin [CPD:C03887];
CO2 [CPD:C00011];
hnu [CPD:C00205]

Comment

Cypridina is a bioluminescent crustacea. The luciferins (and presumably the luciferases, since they cross-react) of some luminous fish (e.g. Apogon, Parapriacanthus, Porichthys) are apparently similar. The enzyme may be assayed by measurement of light emission.

History

EC 1.13.12.6 created 1976, modified 1982

Reference

1 [PMID:5624784]

Authors

Cormier MJ, Crane JM Jr, Nakano Y.

Title

Evidence for the identity of the luminescent systems of Porichthys porosissimus (fish) and Cypridina hilgendorfii (crustacean).

Journal

Biochem Biophys Res Commun 29:747-52 (1967)
DOI:10.1016/0006-291X(67)90281-1

Reference

Authors

Karpetsky, T.P. and White, E.H.

Title

The synthesis of Cypridina etioluciferamine and the proof of the structure of Cypridina luciferin.

Journal

Tetrahedron 29:3761-3773 (1973)

Reference

Authors

Kishi, Y., Goto, T., Hirata, Y., Shiromura, O. and Johnson, F.H.

Title

Cypridina bioluminescence. I. Structure of Cypridina luciferin.

Journal

Tetrahedron Lett 3427-3436 (1966)

Reference

4 [PMID:4433517]

Authors

Tsuji FI, Lynch RV 3rd, Stevens CL.

Title

Some properties of luciferase from the bioluminescent crustacean, Cypridina hilgendorfii.

Journal

Biochemistry 13:5204-9 (1974)
DOI:10.1021/bi00722a024

Other DBs

ExplorEnz - The Enzyme Database:

1.13.12.6

IUBMB Enzyme Nomenclature:

1.13.12.6

ExPASy - ENZYME nomenclature database:

1.13.12.6

BRENDA, the Enzyme Database:

1.13.12.6

CAS:	61969-99-1

All links

Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (6)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (2)   
   GenBank (3)   
Protein domain (2)   
   InterPro (2)   
All databases (20)   

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