KEGG   ENZYME: 1.13.12.6
Entry
EC 1.13.12.6                Enzyme                                 

Name
Cypridina-luciferin 2-monooxygenase;
Cypridina-type luciferase;
luciferase (Cypridina luciferin);
Cypridina luciferase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
Sysname
Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB)
Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + hnu [RN:R04063]
Reaction(KEGG)
R04063
Substrate
Cypridina luciferin [CPD:C02825];
O2 [CPD:C00007]
Product
oxidized Cypridina luciferin [CPD:C03887];
CO2 [CPD:C00011];
hnu [CPD:C00205]
Comment
Cypridina is a bioluminescent crustacea. The luciferins (and presumably the luciferases, since they cross-react) of some luminous fish (e.g. Apogon, Parapriacanthus, Porichthys) are apparently similar. The enzyme may be assayed by measurement of light emission.
History
EC 1.13.12.6 created 1976, modified 1982
Reference
1  [PMID:5624784]
  Authors
Cormier MJ, Crane JM Jr, Nakano Y.
  Title
Evidence for the identity of the luminescent systems of Porichthys porosissimus (fish) and Cypridina hilgendorfii (crustacean).
  Journal
Biochem Biophys Res Commun 29:747-52 (1967)
DOI:10.1016/0006-291X(67)90281-1
Reference
2
  Authors
Karpetsky, T.P. and White, E.H.
  Title
The synthesis of Cypridina etioluciferamine and the proof of the structure of Cypridina luciferin.
  Journal
Tetrahedron 29:3761-3773 (1973)
Reference
3
  Authors
Kishi, Y., Goto, T., Hirata, Y., Shiromura, O. and Johnson, F.H.
  Title
Cypridina bioluminescence. I. Structure of Cypridina luciferin.
  Journal
Tetrahedron Lett:3427-3436 (1966)
Reference
4  [PMID:4433517]
  Authors
Tsuji FI, Lynch RV 3rd, Stevens CL.
  Title
Some properties of luciferase from the bioluminescent crustacean, Cypridina hilgendorfii.
  Journal
Biochemistry 13:5204-9 (1974)
DOI:10.1021/bi00722a024
Other DBs
ExplorEnz - The Enzyme Database: 1.13.12.6
IUBMB Enzyme Nomenclature: 1.13.12.6
ExPASy - ENZYME nomenclature database: 1.13.12.6
BRENDA, the Enzyme Database: 1.13.12.6
CAS: 61969-99-1

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