KEGG   ENZYME: 1.14.11.7
Entry
EC 1.14.11.7                Enzyme                                 
Name
procollagen-proline 3-dioxygenase;
proline,2-oxoglutarate 3-dioxygenase;
prolyl 3-hydroxylase;
protocollagen proline 3-hydroxylase;
prolyl-4-hydroxyprolyl-glycyl-peptide,2-oxoglutarate:oxygen oxidoreductase, 3-hydroxylating
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
Sysname
[procollagen]-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
[procollagen]-L-proline + 2-oxoglutarate + O2 = [procollagen]-trans-3-hydroxy-L-proline + succinate + CO2 [RN:R03218]
Reaction(KEGG)
R03218
Substrate
[procollagen]-L-proline [CPD:C01078];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007]
Product
[procollagen]-trans-3-hydroxy-L-proline [CPD:C04397];
succinate [CPD:C00042];
CO2 [CPD:C00011]
Comment
Requires Fe2+ and ascorbate. The enzyme forms a complex with protein disulfide isomerase, and is located in the endoplasmic reticulum. It modifies proline residues within the procollagen peptide of certain collagen types. The modification is essential for proper collagen triple helix formation.
History
EC 1.14.11.7 created 1981, modified 1983, modified 2017
Orthology
K08134  procollagen-proline 3-dioxygenase 1
K22459  procollagen-proline 3-dioxygenase 2
K22460  procollagen-proline 3-dioxygenase 3
Genes
HSA10536(P3H3) 55214(P3H2) 64175(P3H1)
PTR100612169(P3H3) 456811(P3H1) 740124(P3H2)
PPS100967913(P3H3) 100988847(P3H2) 100995838(P3H1)
GGO101124810(P3H2) 101134181(P3H3) 101141437(P3H1)
PON100445803(P3H2) 100452759(P3H3) 100454619(P3H1)
NLE100579995(P3H2) 100580431(P3H1) 100592815(P3H3)
HMH116463708 116463719 116472603(P3H3) 116479962(P3H2)
MCC697917(P3H1) 704118(P3H2) 713865(P3H3)
MCF102115049(P3H1) 102125709(P3H3) 102137302(P3H2)
MTHB126930430 126948022 126959335
MNI105470865(P3H2) 105484207(P3H3) 105494858(P3H1)
CSAB103218477(P3H3) 103224997(P3H1) 103241897(P3H2)
CATY105575197(P3H2) 105583037(P3H3) 105594659(P3H1)
PANU101023075(P3H1) 101025099(P3H2) 101026956(P3H3)
TGE112619528(P3H2) 112621500(P3H1) 112634137(P3H3)
MLEU105540664(P3H2) 105541806(P3H3) 105555039(P3H1)
RRO104669007(P3H1) 104680052(P3H2) 104680134(P3H3)
RBB108530367(P3H1) 108530476(P3H2) 108542032(P3H3)
TFN117084375(P3H2) 117090611(P3H3) 117092759(P3H1)
PTEH111544367(P3H2) 111548713(P3H1) 111555923(P3H3)
CANG105514008(P3H1) 105519018(P3H3) 105525834(P3H2)
CJC100385724(P3H3) 100388266(P3H2) 100402370(P3H1)
SBQ101029883 101038436(LEPREL1) 101052278(LEPRE1)
CIMI108295001(P3H3) 108313377(P3H1) 108318523(P3H2)
CSYR103274069(P3H2) 103275194(P3H1)
MMUR105860445(P3H2) 105862270(P3H1) 105868996(P3H3)
LCAT123630385(P3H2) 123634275(P3H1) 123640102(P3H3)
PCOQ105805047(P3H3) 105806715(P3H2) 105812312(P3H1)
OGA100951275(P3H3) 100953257(P3H2) 100960942(P3H1)
MMU14789(P3h3) 210530(P3h2) 56401(P3h1)
MCAL110292274(P3h1) 110295793(P3h3) 110311568(P3h2)
MPAH110316244(P3h3) 110322804(P3h1) 110329669(P3h2)
RNO114200(P3h1) 288016(P3h2) 297595(P3h3)
MCOC116085767(P3h2) 116095760(P3h1) 116099583(P3h3)
ANU117708874(P3h1) 117715408(P3h3) 117718224(P3h2)
MUN110542144(P3h2) 110547455(P3h1) 110548595(P3h3)
CGE100752370(P3h2) 100767056(P3h3) 100769529(P3h1)
MAUA101842039(P3h3) 101843136(P3h2) 101844959(P3h1)
PROB127212848(P3h3) 127225263(P3h1) 127227019(P3h2)
PLEU114697097(P3h2) 114704940(P3h1) 114708824(P3h3)
MORG121443056(P3h3) 121448761(P3h1) 121465132(P3h2)
MFOT126512308 126513092 126514890
AAMP119807780(P3h3) 119817502(P3h1) 119824997(P3h2)
NGI103727504(P3h3) 103739336(P3h2) 103741906(P3h1)
HGL101709763(P3h2) 101719240(P3h3) 101725544(P3h1)
CPOC100713593(P3h2) 100714440(P3h1) 100734213(P3h3)
CCAN109678351(P3h2) 109682771(P3h3) 109691192(P3h1)
DORD105986002(P3h1) 105987863(P3h2) 105991075(P3h3)
DSP122098574(P3h2) 122101947(P3h3) 122110913(P3h1)
PLOP125351879(P3h2) 125355008(P3h1)
NCAR124964291 124982086 124993301
MMMA107141881(P3h1) 107154377(P3h2) 107154941(P3h3)
OCU100344567 100356128 100357143
OPI101532483(P3H3) 101533941(P3H2) 101534730(P3H1)
TUP102468745(P3H1) 102489939(P3H3) 102490664(P3H2)
GVR103586410(LEPREL2) 103590826(LEPRE1) 103593056(LEPREL1)
CFA100686626(P3H3) 478674(P3H2) 606980(P3H1)
CLUD112642256(P3H1) 112645824(P3H2) 112675352(P3H3)
VVP112908251(P3H1) 112917513(P3H3) 112926308(P3H2)
VLG121477368(P3H2) 121479875(P3H3) 121481251(P3H1)
NPO129498620(P3H2) 129503453(P3H3) 129520625(P3H1)
AML100477435(P3H1) 100482440(P3H3) 100484169(P3H2)
UMR103656188(P3H3) 103670920(P3H1) 103676024(P3H2)
UAH113253554(P3H2) 113254805(P3H1) 113257960(P3H3)
UAR123781658(P3H3) 123793817(P3H1) 123801275(P3H2)
ELK111143043 111149280 111159772
LLV125097086 125102140 125106049
MPUF101681875(P3H2) 101682820(P3H1) 101683319(P3H3)
MNP132000695(P3H1) 132011938(P3H2) 132019911(P3H3)
MLK131809104(P3H1) 131824729(P3H2) 131838463(P3H3)
NVS122892607(P3H3) 122899840(P3H1) 122908804(P3H2)
ORO101366397(P3H1) 101370866(P3H3) 101373687(P3H2)
EJU114207098(P3H2) 114222611(P3H3) 114224201(P3H1)
ZCA113911494(P3H1) 113918448(P3H2) 113921347(P3H3)
MLX118006941(P3H2) 118019539(P3H1) 118025727(P3H3)
NSU110574953(P3H1) 110580950(P3H3) 110582618(P3H2)
LWW102731281(P3H2) 102741085(P3H3) 102743362(P3H1)
FCA101093365(P3H3) 101094278(P3H1) 101094873(P3H2)
PYU121021963(P3H3) 121026960(P3H1) 121034146(P3H2)
PCOO112849643(P3H2) 112863374(P3H1) 112867653(P3H3)
PBG122472380(P3H3) 122480360(P3H1) 122491612(P3H2)
PVIV125169795(P3H3) 125172939(P3H1) 125175131(P3H2)
LRUF124500963 124515996 124527028
PTG102950281(P3H2) 102955345(P3H3) 102958232(P3H1)
PPAD109254903(P3H1) 109275310(P3H2) 109276105(P3H3)
PUC125912702 125917978 125917988 125921087
AJU106965441 106968016 106970202
HHV120220442(P3H3) 120233112(P3H2) 120236066(P3H1)
BTA132345345(P3H3) 511799(P3H2) 539976(P3H1)
BOM102280597(P3H1) 102284601(P3H2) 102287577(P3H3)
BIU109556425(P3H1) 109556764(P3H2) 109558918(P3H3)
BBUB102394493(P3H3) 102395789(P3H1) 102400880(P3H2)
BBIS104992333(LEPREL2) 104996454(P3H2) 105004889(P3H1)
CHX102176848(P3H1) 102188119(P3H3) 102189992(P3H2)
OAS101105862(P3H1) 101108618(P3H2) 101108826(P3H3)
BTAX128044509(P3H1) 128047896(P3H3) 128049104(P3H2)
ODA120856313(P3H1) 120858735(P3H3) 120872670(P3H2)
CCAD122423967(P3H3) 122437120(P3H1) 122444797(P3H2)
MBEZ129536554(P3H3) 129541670(P3H1) 129544467(P3H2)
SSC100156539(P3H3) 100520219(P3H2) 100620503(P3H1)
CFR102510969(P3H3) 102516638(P3H2) 102516978(P3H1)
CBAI105071089(LEPREL2) 105072351(P3H2) 105072736(P3H1)
CDK105097544(P3H2) 105098205(P3H3) 105103354(P3H1)
VPC102524649(P3H2) 102530387(P3H3) 102532573(P3H1)
BACU103005242(P3H2) 103015069(P3H3) 103015131(P3H1)
BMUS118894735(P3H2) 118899981(P3H1) 118902279(P3H3)
LVE103076723(LEPREL1) 103081402(LEPRE1) 103090013(LEPREL2)
OOR101273511(P3H1) 101285801(P3H3) 101289013(P3H2)
DLE111172711(P3H2) 111175681(P3H1) 111176688(P3H3) 111176693
PCAD102977913(P3H1) 102981742(P3H3) 102993003(P3H2)
PSIU116753392(P3H2) 116755713(P3H1) 116760195(P3H3)
NASI112391958(P3H3) 112399526(P3H1) 112415541(P3H2)
ECB100059777(P3H2) 100060032(P3H3) 100067315(P3H1)
EPZ103547016(P3H3) 103557310(P3H1) 103564888(P3H2)
EAI106832556(P3H2) 106847326(P3H3) 106847794(P3H1)
MYB102239815(P3H1) 102245885(P3H2) 102248956(P3H3)
MYD102755248(P3H3) 102759591(P3H2) 102764443(P3H1)
MMYO118649723(P3H3) 118676394(P3H2) 118676688(P3H1)
MLF102423043(P3H2) 102427832(P3H1) 102428125(P3H3)
PKL118724644(P3H1) 118724946(P3H2) 118730176(P3H3)
EFUS103289026(P3H3) 103294839(P3H1) 103295161(P3H2)
MNA107527300(P3H2) 107531174(P3H1) 107543975(P3H3)
DRO112299410(P3H1) 112300959(P3H2) 112321730(P3H3)
SHON118977594(P3H1) 118981928(P3H2) 119002342(P3H3)
AJM119039095(P3H2) 119052336(P3H1) 119060498(P3H3)
PDIC114491032(P3H2) 114497760(P3H1) 114513537(P3H3)
PHAS123810637(P3H3) 123827488(P3H2) 123831600(P3H1)
MMF118617224(P3H2) 118623938(P3H3) 118626294(P3H1)
PPAM129069364(P3H1) 129071437(P3H3) 129071438 129079878(P3H2)
HAI109371222(P3H2) 109373668(P3H3) 109383352(P3H1)
RFQ117012781(P3H2) 117027319(P3H1) 117028942(P3H3)
PALE102884197(P3H1) 102890385(P3H2) 102893257(P3H3)
PGIG120592972(P3H2) 120607189(P3H1) 120611662(P3H3)
PVP105296021(P3H3) 105304022(P3H1) 105307800
RAY107505908(P3H2) 107508292(P3H1) 107519795(P3H3)
MJV108384714(P3H2) 108403547(P3H3) 108410378
TOD119235556(P3H1) 119247773(P3H3) 119257389(P3H2)
SARA101537434(P3H2) 101545227(P3H3) 101545776(P3H1)
SETR126006662(P3H3) 126011706(P3H1) 126012199(P3H2)
LAV100658405(P3H2) 100665625(P3H1) 100675290(P3H3)
TMU101343909 101346635 101349558
ETF101660051(P3H1) 101661521(P3H3) 101664172(P3H2)
DNM101417141(P3H1) 101419290(P3H2) 101447593(P3H3)
MDO100016121(P3H3) 100032694(P3H1) 100618320(P3H2)
GAS123242798(P3H2) 123243213(P3H1) 123248676(P3H3)
SHR100914814(P3H1) 100923448(P3H3) 100933913(P3H2)
AFZ127539232 127555550 127558328
PCW110193120(P3H2) 110206219(P3H1) 110213786(P3H3)
OAA100081783(P3H2) 100085351(P3H1) 103168172(P3H3)
GGA414142(P3H1) 414143(P3H2) 418289(P3H3)
PCOC116235341(P3H2) 116238345(P3H1) 116239939(P3H3)
MGP100546471(P3H1) 100548323(P3H3) 100549834(P3H2)
CJO107318275(P3H2) 107318675(P3H3) 107323389(P3H1)
TPAI128082823(P3H2) 128085110(P3H1) 128089880(P3H3)
LMUT125685211(P3H3) 125697625(P3H2) 125703394(P3H1)
NMEL110398259(P3H2) 110398399(P3H3) 110408525(P3H1)
APLA101793572(P3H1) 101794735(P3H3) 101795167(P3H2)
ACYG106044830(P3H2) 106047855(P3H3) 106049155(P3H1)
CATA118247024(P3H2) 118247623(P3H3) 118258801(P3H1)
AFUL116492502(P3H2) 116497562(P3H1) 116502297(P3H3)
TGU100221140(P3H3) 100221254(P3H1) 100224069(P3H2)
LSR110472240(P3H1) 110473861(P3H2) 110480812(P3H3)
SCAN103812452(P3H3) 103815383(P3H2) 103824173
PMOA120498992(P3H1) 120504367(P3H2) 120506513(P3H3)
OTC121333074(P3H1) 121336673(P3H2) 121339254(P3H3)
PRUF121351585(P3H3) 121353848(P3H2) 121365790(P3H1)
GFR102036321(P3H1) 102040203(P3H3) 102040654(P3H2)
FAB101810645(P3H3) 101821011(P3H2) 101821087(P3H1)
OMA130256065(P3H3) 130256681(P3H2) 130261692(P3H1)
PHI102099220(P3H2) 102106882(P3H1) 102112679(P3H3)
PMAJ107208918(P3H2) 107213395(P3H3) 107213791(P3H1)
CCAE111933453(P3H2) 111938269(P3H3) 111938574(P3H1)
CCW104687224(P3H3) 104687928(P3H2) 104697539(P3H1)
CBRC103614062(P3H3) 103616210(P3H1) 103625159(P3H2)
ETL114057609(P3H2) 114058157(P3H3) 114066843(P3H1)
ZAB102063366(P3H3) 102064950(P3H1) 102074218(P3H2)
ZLE135451696(P3H2) 135453012(P3H3) 135456658(P3H1)
ACHL103797120(LEPRE1) 103797628(LEPREL2) 103811737(LEPREL1)
SVG106856449(P3H1) 106857894(P3H3) 106862517(P3H2)
MMEA130574783(P3H3) 130579652(P3H2) 130583070(P3H1)
HRT120748508(P3H3) 120757354(P3H2) 120762314(P3H1)
FPG101917584(P3H2) 101919025(P3H3) 101923126(P3H1)
FCH102048595(P3H1) 102050123(P3H2) 102055974(P3H3)
CLV102084407(P3H3) 102094017(P3H1) 102097675(P3H2)
EGZ104123376(LEPREL1) 104126599(LEPREL2) 104131732(LEPRE1)
NNI104011258(LEPRE1) 104015666(LEPREL1) 104022495(LEPREL2)
PCRI104026902(LEPRE1) 104028695(LEPREL2) 104035992(LEPREL1)
PLET104620548(LEPRE1) 104624766(LEPREL2) 104628721(LEPREL1)
EHS104504088(LEPRE1) 104513521(LEPREL2) 104514259(LEPREL1)
PCAO104042731(LEPRE1) 104049585(LEPREL1) 104052979(LEPREL2)
ACUN113476602(P3H3) 113483556(P3H2) 113487825(P3H1)
TALA104360794(P3H2) 104363765(P3H3) 104369444(P3H1)
PADL103921957(LEPREL2) 103925387(LEPREL1) 103925411(LEPRE1)
AFOR103901461(P3H2) 103905500(P3H3) 103906904(P3H1)
ACHC115343286(P3H1) 115343592(P3H3) 115347537(P3H2)
HALD104319100(LEPREL2) 104322359(LEPREL1)
HLE104831865(LEPREL2) 104835183(LEPREL1) 104837978(LEPRE1)
AGEN126037674 126039707 126049044
GCL127014949 127020268 127024724
CCRI104157321(LEPRE1) 104160056(LEPREL2) 104167788(LEPREL1)
CSTI104553598(LEPREL1) 104563840(LEPREL2)
CMAC104476527(LEPREL1) 104482091(LEPREL2) 104485602
MUI104544288(LEPRE1) 104544823(LEPREL1) 104545881(LEPREL2)
BREG104638771(LEPRE1) 104641458(LEPREL2) 104643058(LEPREL1)
FGA104081373(LEPREL1)
GSTE104255997 104259959 104262938(LEPREL1)
LDI104342865(LEPRE1) 104350897(LEPREL2) 104353045(LEPREL1)
MNB103773606(LEPREL1) 103780783 103782521(LEPRE1)
OHA104326848(LEPREL1) 104327155(LEPREL2) 104332999(LEPRE1)
NNT104402307(LEPREL2) 104403959(LEPREL1) 104412546(LEPRE1)
SHAB115601647(P3H3) 115611985(P3H2) 115617506(P3H1)
DPUB104299503(LEPREL2) 104300715(LEPREL1) 104305543(LEPRE1)
PGUU104459157(LEPREL2) 104471184(LEPREL1)
ACAR104521329(P3H2) 104532899(P3H3)
CPEA104389885(LEPREL2) 104390642(LEPRE1) 104390686(LEPREL1)
AVIT104268188(LEPREL2) 104270701(LEPREL1) 104276757(LEPRE1)
CVF104284970(LEPREL1) 104290705(LEPRE1) 104293416(LEPREL2)
RTD128904353(P3H3) 128911226(P3H2) 128918447(P3H1)
CUCA104063443(LEPREL1) 104064399(LEPREL2) 104065419(LEPRE1)
TEO104371718(LEPREL1) 104374330(LEPREL2) 104380509(LEPRE1)
BRHI104493337(LEPREL1) 104498149(LEPREL2) 104500747(LEPRE1)
AAM106497271(P3H3) 106498214(P3H2) 106498600(P3H1)
AROW112966878(P3H1) 112968533(P3H2) 112973011(P3H3)
NPD112952573(P3H2) 112957490(P3H1) 112960149(P3H3)
TGT104565680(LEPREL2) 104575329(LEPREL1) 104580913(LEPRE1)
DNE112979395(P3H2) 112988486(P3H1) 112991070(P3H3)
SCAM104148800(LEPREL1) 104150749(LEPREL2) 104153657(LEPRE1)
ASN102368146 102380538 102384024 102385273(P3H1)
AMJ102562134(P3H3) 102572352(P3H2) 106737225(P3H1)
CPOO109308549(P3H2) 109314287(P3H1) 109319392(P3H3)
GGN109288104(P3H2) 109293875(P3H1) 109304603(P3H3)
PSS102444832(P3H2) 102450598(P3H1) 102461480(P3H3)
CMY102929854(P3H3) 102932162(P3H1) 102939997(P3H2)
CCAY125622645(P3H3) 125624325(P3H1) 125642646(P3H2)
DCC119845112(P3H1) 119845973(P3H3) 119861544(P3H2)
CPIC101931004(P3H3) 101931818(P3H2) 101935857(P3H1)
TST117867966(P3H1) 117882815(P3H2) 117885801(P3H3)
CABI116817602(P3H1) 116823027(P3H2) 116837548(P3H3)
MRV120372389(P3H2) 120387981(P3H1) 120401768(P3H3)
ACS100562772(p3h2) 100567613(p3h3)
ASAO132764714(P3H1) 132767535(P3H3) 132770370(P3H2)
PVT110084656(P3H3) 110085947(P3H2) 110086810(P3H1)
SUND121923805(P3H3) 121927252(P3H2) 121937202(P3H1)
PBI103048096(P3H2) 103049535(P3H3) 103066967(P3H1)
PMUR107285772 107290023(P3H1) 107299512
CTIG120306096(P3H3) 120319197(P3H1) 120319828(P3H2)
TSR106545546
PGUT117661815(P3H3) 117669822(P3H2)
APRI131187117(P3H1) 131191768(P3H3) 131201205(P3H2)
PTEX113444487(P3H3) 113451599(P3H1)
NSS113424512(P3H3) 113427581(P3H1)
VKO123031046(P3H1) 123033251(P3H3) 123036774(P3H2)
PMUA114587602(P3H3) 114598127(P3H2) 114602593(P3H1)
PRAF128405255(P3H3) 128414905(P3H2) 128419653(P3H1)
ZVI118075322(P3H3) 118087616(P3H1) 118093536(P3H2)
HCG128338715(P3H1) 128342814(P3H3) 128351902(P3H2)
GJA107116689(P3H1) 107116803(P3H3) 107123825(P3H2)
STOW125436260(P3H3) 125438562(P3H2) 125446058(P3H1)
EMC129332204(P3H2) 129344677(P3H1) 129345649(P3H3)
XLA108697338(p3h3.S) 108716969(p3h2.L) 108718050 414447(p3h1.L)
XTR100036679(p3h1) 100496461(p3h2) 101734514 101734646 116406429(p3h3)
NPR108783932(P3H1) 108795998(P3H3) 108804588(P3H2)
RTEM120915618(P3H1) 120936859(P3H2) 120946604(P3H3)
BBUF120997981(P3H2) 120998118(P3H1) 121004655(P3H3)
BGAR122926236(P3H1) 122934556(P3H2) 122942224(P3H3)
MUO115456652(P3H1) 115458019(P3H3) 115478957(P3H2)
GSH117349168(P3H1) 117350202(P3H3) 117366300(P3H2)
DRE553311(p3h3) 553321(p3h1) 566697(p3h2)
SRX107715694 107722092 107724912 107741542(p3h2) 107751183 107756620
SANH107654364(p3h1) 107654416 107655408(p3h2) 107664742 107700158
SGH107549451(p3h3) 107560692 107564922 107565728(p3h1) 107582441
CCAR109048696 109051947 109081049 109092890 109103994
CAUA113039910 113055510 113064960 113110859 113116390
CGIB127943251 127968386 127974344 127988386 128022084
PTET122328056(p3h2) 122354651(p3h1) 122360143(p3h3)
LROH127173193(p3h1) 127177921(p3h3)
OMC131522304(p3h3) 131530023(p3h2) 131549908(p3h1)
PPRM120477226(p3h2) 120480458(p3h1) 120484283(p3h3)
RKG130103670(p3h3)
MAMB125244021(p3h3) 125252770(p3h2) 125256150(p3h1)
CIDE127497553 127521119 127522837
MASI127426077 127438258 127439179 127453420 127453951
TROS130548367(p3h2) 130558448(p3h3) 130571241(p3h1)
TDW130410282(p3h1) 130430716(p3h2) 130433480(p3h3)
MANU129427410(p3h1) 129447880(p3h3) 129453530(p3h2)
IPU108270766 108274273 108281059
IFU128608075(p3h3) 128613508(p3h2) 128624984(p3h1)
PHYP113537803(p3h1) 113542320(p3h3) 113547067(p3h2)
SMEO124385187(p3h3) 124391591(p3h2) 124402570(p3h1)
TFD113641863(p3h3) 113646193(p3h2) 113657265(p3h1)
TVC132838266(p3h1) 132846103(p3h3) 132850994(p3h2)
TRN134302130(p3h1) 134307489 134310304(p3h3) 134331147(p3h2)
AMEX103024133(p3h1) 103026715(p3h3) 103045377(p3h2)
CMAO118799918(p3h1) 118818729(p3h2) 118824794(p3h3)
EEE113570617(p3h3) 113582372(p3h2) 113586117(p3h1)
CHAR105895157(p3h3) 105895868(p3h1) 105910695(p3h2)
TRU101075372(p3h3) 101075489(p3h1) 101076075(p3h2)
TFS130523752(p3h1) 130528194(p3h2) 130532927(p3h3)
TNGGSTEN00014179G001 GSTEN00015313G001 GSTEN00028918G001 GSTEN00028919G001
LCO104920250(p3h2) 104922230(p3h3) 104939521(p3h1)
NCC104950703 104957626(p3h1) 104965937
TBEN117475688(p3h1) 117494786(p3h3) 117495711(p3h2)
CGOB115007391(p3h2) 115008260(p3h1)
PGEO117445153(p3h2) 117446711(p3h1) 117460707(p3h3)
GACU117532965(p3h1) 117549559(p3h3) 117555098(p3h2)
EMAC134861241(p3h3) 134869684(p3h2) 134883534(p3h1)
ELY117254207(p3h2) 117260457(p3h1) 117265415(p3h3)
EFO125885462(p3h1) 125893104(p3h3) 125895266(p3h2)
PLEP121945239(p3h3) 121951726(p3h1) 121966392(p3h2)
SLUC116036624 116049730(p3h3) 116055318(p3h2)
ECRA117942804(p3h1) 117946205(p3h3) 117950637(p3h2)
ESP116691224(p3h3) 116695386(p3h2)
PFLV114554208(p3h1) 114557467(p3h3) 114562108(p3h2)
GAT120810814(p3h3) 120823947(p3h2) 120835102(p3h1)
PPUG119197220(p3h3) 119216991(p3h2) 119229818(p3h1)
AFB129094470(p3h2) 129105848(p3h1) 129109527(p3h3)
CLUM117730104(p3h2) 117731391(p3h1) 117745453(p3h3)
PSWI130193791(p3h2) 130213447(p3h3)
MSAM119886929(p3h1) 119897412(p3h3) 119900664(p3h2)
SCHU122877277(p3h2) 122882018(p3h3) 122883130(p3h1)
CUD121507571(p3h1) 121512077(p3h2) 121513008(p3h3)
ALAT119006313(p3h3) 119021918(p3h1) 119028168(p3h2)
MZE101465294(p3h1) 101479402(p3h2) 101486114(p3h3)
ONL100699187(p3h2) 100708165(p3h1) 100708642(p3h3)
OAU116323755(p3h3) 116324692(p3h2) 116332067(p3h1)
OLA101170663(p3h2) 101171860(p3h3) 101172073(p3h1)
OML112143647(p3h3) 112144912(p3h1) 112150784(p3h2)
CSAI133435175(p3h3) 133449179(p3h1) 133458453(p3h2)
XMA102223713(p3h2) 102234680(p3h3) 102238287(p3h1)
XCO114136016(p3h1) 114142259(p3h3) 114150787(p3h2)
XHE116711012(p3h1) 116717846(p3h3) 116725527(p3h2)
PRET103464183(p3h2) 103465445(p3h1) 103477971(p3h3)
PFOR103136767(p3h3) 103138543(p3h2) 103150287(p3h1)
PLAI106951135(p3h3) 106955524(p3h2) 106956034(p3h1)
PMEI106920146(p3h1) 106926283(p3h2) 106927927(p3h3)
GAF122830987(p3h3) 122833669(p3h1) 122838659(p3h2)
PPRL129358160(p3h1) 129371158(p3h3) 129372421(p3h2)
CVG107082187(p3h3) 107101026(p3h2) 107104181(p3h1)
CTUL119774605(p3h2) 119777180(p3h1) 119783137(p3h3)
GMU124857160(p3h1) 124865506(p3h3) 124874119(p3h2)
NFU107373178 107379477(p3h3) 107392670(p3h2)
KMR108230631(p3h2) 108235396(p3h3) 108250443(p3h1)
ALIM106521056(p3h3) 106527403(p3h1) 106537303(p3h2)
NWH119407796(p3h2) 119409373(p3h3) 119411644(p3h1)
AOCE111571080(p3h3) 111574099(p3h1) 111578231 111585771(p3h2)
MCEP125007430(p3h1) 125009368(p3h2) 125015765(p3h3)
CSEM103386606(p3h1) 103387968(p3h3) 103392998(p3h2)
POV109625858(p3h2) 109629287(p3h1) 109633247(p3h3)
SSEN122760895(p3h1) 122774119(p3h3) 122780942(p3h2)
HHIP117759980(p3h2) 117761748(p3h1) 117776777(p3h3)
HSP118105215(p3h1) 118113174(p3h3) 118121489(p3h2)
PPLT128448709(p3h2) 128450031(p3h3) 128458701(p3h1)
SMAU118309308(p3h1) 118314808(p3h3) 118317710(p3h2)
LCF108877527 108880725 108881307
SDU111217020(p3h2) 111221750(p3h1) 111230047(p3h3)
SLAL111650235(p3h2) 111668691(p3h1) 111669862(p3h3)
XGL120783468(p3h1) 120784068(p3h3) 120790884(p3h2)
HCQ109515135(p3h1) 109515281(p3h3) 109522012(p3h2)
SSCV125969480 125975665 125976992
SBIA133500694(p3h3) 133504147(p3h2) 133507035(p3h1)
PEE133401406(p3h3) 133406398(p3h2) 133408613(p3h1)
PTAO133479109(p3h3) 133480551(p3h2) 133483174(p3h1)
BPEC110160074(p3h2) 110163193(p3h3) 110171175(p3h1)
MALB109953105 109953107 109958232(p3h2) 109966171(p3h3)
BSPL114843080(p3h3) 114854438(p3h2) 114856242(p3h1)
SJO128355600(p3h1) 128361887(p3h2) 128365823(p3h3)
SASA106565637(p3h1) 106573995 106583105 106583419 106605089 106613518
STRU115150640 115151549 115157986 115176450 115177280 115207766
OTW112218132(p3h1) 112223120 112246567 112250630(p3h2) 112253254 112254543
OMY110489468 110494379(p3h1) 110518017(p3h3) 110524034 110528058 110534688
OGO123997218 123997415 123997954 124003057(p3h1) 124005572(p3h3) 124020035
ONE115108076 115139366 115141338 115141339 115143227(p3h1)
OKI109889038 109891088 109896147(p3h1) 109902181(p3h3) 109902278 109910242
OKE118364243 118367318 118370845 118386998 118388516(p3h1) 118401550
SALP111952665 111965230(p3h3) 111965231 111970041 111975684 111975807
SNH120031264 120047544 120053647 120054624 120060877(p3h1) 120065128 120065944
CCLU121533753(p3h2) 121564971(p3h3) 121575310(p3h1) 121576538 121577669
ELS105007738(p3h2) 105028240(p3h3) 105030006(p3h1)
SFM108922091(p3h3) 108937368(p3h2) 108938176(p3h1)
PKI111835368(p3h3) 111836557 111838779
AANG118209301(p3h3) 118210623(p3h1) 118226537(p3h2)
LOC102685978(p3h1) 102689642(p3h3) 102697448(p3h2)
PSPA121323343 121325618(p3h3) 121325619 121327002 121328843 121329236
ARUT117417318 117422935 117425925(p3h3) 117432040(p3h1)
PSEX120530950(p3h1) 120535749(p3h3) 120537172(p3h2)
LCM102348936(P3H3) 102353193(P3H2) 102356877(P3H1)
CMK103181352(p3h1) 103191590
RTP109915299(p3h1) 109919539
CPLA122540219(p3h1) 122556097(p3h2)
HOC132821821(p3h2) 132825300 132833504(p3h1)
LERI129703436(p3h2) 129710491 129711432(p3h1)
PMRN116946894(P3H1)
LRJ133351137(P3H1)
BFO118424124 118430516
BBEL109478102 109484134
CIN445606(leprecan)
SCLV120328236
APLC110983136
SKO100313646
AME725819
ACER108003674
ALAB122720818
ADR102674496
AFLR100864260
BIM100740426
BBIF117211594
BVK117241281
BVAN117158597
BTER100650141
BAFF126919223
BPYO122566466
BPAS132910915
FVI122538823
CCAL108630344
OBB114873602
OLG117600929
MGEN117229130
NMEA116429887
CGIG122399782
SOC105202130
MPHA105840059
AEC105148061
ACEP105624115
PBAR105427498
VEM105568238
HST105190225
DQU106747649
CFO105259052
FEX115244475
LHU105679345
PGC109859021
OBO105282343
PCF106788117
PFUC122518292
VVE124950922
NVI100123941
CSOL105366801
TPRE106658373
MDL103575387
CGLO123269381
FAS105263645
DAM107045680
AGIF122851580
VCAN122414355
CCIN107267355
TCA657387
CSET123312060
AGB108916913
DVV126893009
NVL108566762
OTU111414178
FOC113209395
TPAL117639497
ZNE110827209
CSEC111870092
PVM113810720
PJA122264075
PMOO119587995
HAME121877169
PCLA123771862
CQD128689794
PTRU123508532
ESN126983829
MNZ135219964
HAZT108668164
LSM121127797
PPOI119092956 119112432
DSV119434090 119435045 119435461
RSAN119381732 119404933
RMP119165004 119181775
CSCU111620029 111620050
PTEP107455616
ABRU129964166
UDV129216476 129216477
SDM118194559
LPOL106457621
HROHELRODRAFT_181486
LGILOTGIDRAFT_91939
PVUL126825556
PCAN112559825
BGT106069840
GAE121381414
HRF124115558
HRJ124262637
CRG105325684
MYI110459992 110459993
PMAX117335915 117336334
MMER123536171
RPHI132735786
OSN115211627
LAK106160773
LLON135492172
NVE5517048
EPA110243698
ATEN116308765
ADF107344196
AMIL114949534
PDAM113667901
DGT114523086
XEN124453691
HMG100203735
HSY130628607
AQU100638799
GMX100788718
GSJ114421545
PVUPHAVU_002G181600g
VRA106768895
VAR108347895
VUN114178277
VUM124844233
LJALj4g3v2406420.1(Lj4g3v2406420.1)
LANG109359831
PCIN129311333
CSV101218213
CMO103496668
CMAX111487019
 » show all
Reference
1  [PMID:191255]
  Authors
Risteli J, Tryggvason K, Kivirikko KI.
  Title
Prolyl 3-hydroxylase: partial characterization of the enzyme from rat kidney cortex.
  Journal
Eur J Biochem 73:485-92 (1977)
DOI:10.1111/j.1432-1033.1977.tb11341.x
Reference
2  [PMID:204218]
  Authors
Risteli J, Tryggvason K, Kivirikko KI.
  Title
A rapid assay for prolyl 3-hydroxylase activity.
  Journal
Anal Biochem 84:423-31 (1978)
DOI:10.1016/0003-2697(78)90060-X
Reference
3  [PMID:15044469]
  Authors
Vranka JA, Sakai LY, Bachinger HP
  Title
Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes.
  Journal
J Biol Chem 279:23615-21 (2004)
DOI:10.1074/jbc.M312807200
  Sequence
[gga:414142]
Reference
4  [PMID:18487197]
  Authors
Tiainen P, Pasanen A, Sormunen R, Myllyharju J
  Title
Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV.
  Journal
J Biol Chem 283:19432-9 (2008)
DOI:10.1074/jbc.M802973200
  Sequence
[hsa:55214]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.11.7
IUBMB Enzyme Nomenclature: 1.14.11.7
ExPASy - ENZYME nomenclature database: 1.14.11.7
BRENDA, the Enzyme Database: 1.14.11.7
CAS: 63551-75-7

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