KEGG   ENZYME: 1.14.13.14
Entry
EC 1.14.13.14               Enzyme                                 
Name
trans-cinnamate 2-monooxygenase;
cinnamic acid 2-hydroxylase;
cinnamate 2-monooxygenase;
cinnamic 2-hydroxylase;
cinnamate 2-hydroxylase;
trans-cinnamic acid 2-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)
Reaction(IUBMB)
trans-cinnamate + NADPH + H+ + O2 = 2-hydroxycinnamate + NADP+ + H2O [RN:R02254]
Reaction(KEGG)
R02254
Substrate
trans-cinnamate [CPD:C00423];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
2-hydroxycinnamate [CPD:C01772];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
History
EC 1.14.13.14 created 1976
Pathway
ec00360  Phenylalanine metabolism
ec00999  Biosynthesis of various plant secondary metabolites
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:4153528]
  Authors
Gestetner B, Conn EE.
  Title
The 2-hydroxylation of trans-cinnamic acid by chloroplasts from Melilotus alba Desr.
  Journal
Arch Biochem Biophys 163:617-24 (1974)
DOI:10.1016/0003-9861(74)90522-0
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.14
IUBMB Enzyme Nomenclature: 1.14.13.14
ExPASy - ENZYME nomenclature database: 1.14.13.14
BRENDA, the Enzyme Database: 1.14.13.14
CAS: 53126-56-0

  All links  
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
All databases (19)   

Download RDF
DBGET integrated database retrieval system