KEGG   ENZYME: 1.14.13.16
Entry
EC 1.14.13.16               Enzyme                                 
Name
cyclopentanone monooxygenase;
cyclopentanone oxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)
Reaction(IUBMB)
cyclopentanone + NADPH + H+ + O2 = 5-valerolactone + NADP+ + H2O [RN:R02554]
Reaction(KEGG)
R02554
Substrate
cyclopentanone [CPD:C00557];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
5-valerolactone [CPD:C02240];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
History
EC 1.14.13.16 created 1976
Orthology
K23517  cyclopentanone monooxygenase
Reference
1  [PMID:4349113]
  Authors
Griffin M, Trudgill PW.
  Title
The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872.
  Journal
Biochem J 129:595-603 (1972)
DOI:10.1042/bj1290595
Reference
2  [PMID:4313]
  Authors
Griffin M, Trudgill PW.
  Title
Purification and properties of cyclopentanone oxygenase of Pseudomonas NCIB 9872.
  Journal
Eur J Biochem 63:199-209 (1976)
DOI:10.1111/j.1432-1033.1976.tb10222.x
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.16
IUBMB Enzyme Nomenclature: 1.14.13.16
ExPASy - ENZYME nomenclature database: 1.14.13.16
BRENDA, the Enzyme Database: 1.14.13.16
CAS: 37364-15-1

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