KEGG   ENZYME: 1.14.13.226Help
Entry
EC 1.14.13.226              Enzyme                                 

Name
acetone monooxygenase (methyl acetate-forming);
acmA (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
acetone,NADPH:oxygen oxidoreductase (methyl acetate-forming)
Reaction(IUBMB)
acetone + NADPH + H+ + O2 = methyl acetate + NADP+ + H2O [RN:R10704]
Reaction(KEGG)
Substrate
acetone [CPD:C00207];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
methyl acetate [CPD:C17530];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Contains FAD. The enzyme, characterized from the bacterium Gordonia sp. TY-5, is a Baeyer-Villiger type monooxygenase and participates in a propane utilization pathway.
History
EC 1.14.13.226 created 2016
Pathway
ec00640  Propanoate metabolism
ec01100  Metabolic pathways
Orthology
K18371  acetone monooxygenase (methyl acetate-forming)
Genes
GAI: IMCC3135_04360(pamO)
MPT: Mpe_B0610
METR: BSY238_2655(pamO)
BIC: LMTR13_14840
BRK: CWS35_07445
BOT: CIT37_15830
BID: Bind_3904
DSH: Dshi_2283(pamO)
TOM: BWR18_02365
SAGU: CDO87_05620
TMO: TMO_c0213(pamO)
GBR: Gbro_0088
GOM: D7316_03881(pamO_3)
NML: Namu_3461
GOB: Gobs_1837
 » show all
Taxonomy
Reference
1  [PMID:17071761]
  Authors
Kotani T, Yurimoto H, Kato N, Sakai Y.
  Title
Novel acetone metabolism in a propane-utilizing bacterium, Gordonia sp. strain TY-5.
  Journal
J Bacteriol 189:886-93 (2007)
DOI:10.1128/JB.01054-06
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.226
IUBMB Enzyme Nomenclature: 1.14.13.226
ExPASy - ENZYME nomenclature database: 1.14.13.226
BRENDA, the Enzyme Database: 1.14.13.226

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