KEGG   ENZYME: 1.14.13.235
Entry
EC 1.14.13.235              Enzyme                                 
Name
indole-3-acetate monooxygenase;
iacA (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
(indol-3-yl)acetate,NADH:oxygen oxidoreductase (2-hydroxylating)
Reaction(IUBMB)
(indol-3-yl)acetate + NADH + H+ + O2 = (2-hydroxy-1H-indol-3-yl)acetate + NAD+ + H2O [RN:R11730]
Reaction(KEGG)
R11730
Substrate
(indol-3-yl)acetate [CPD:C00954];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
(2-hydroxy-1H-indol-3-yl)acetate [CPD:C21619];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Comment
The enzyme, characterized from Pseudomonas putida strains, catalyses the first step in a pathway for degradation of the plant hormone indole-3-acetate. When acting on indole, the enzyme forms indoxyl, which reacts spontaneously with oxygen to form the blue dye indigo.
History
EC 1.14.13.235 created 2017
Orthology
K22027  indole-3-acetate monooxygenase
Genes
EFE: EFER_0795
EPT: HWQ17_22670
EAS: Entas_2482
EAE: EAE_02315
EAR: CCG33524
ROR: RORB6_23125
RON: TE10_23150
RPLN: B1209_04450
RAO: DSD31_04580
KGO: CEW81_10430
KIE: NCTC12125_01038(hsaA_1)
KAS: KATP_26500
KLU: K7B04_19210
KCY: RIN60_09550
LAX: APT61_09000
LEI: C2U54_18520
LEH: C3F35_21230
LEE: DVA44_09630
LER: GNG29_13055
LEA: GNG26_13325
LEY: DVA43_04225
LEF: LJPFL01_2408
LEW: DAI21_14150
BUF: D8682_22140
BFT: MNO13_06485
BSEL: RHD99_06405
SGOE: A8O29_009730
IZH: FEM41_10700
PSGC: G163CM_02870(hsaA)
EBF: D782_1303
ERWE: GKQ23_07130
XTN: FD63_14490
XGM: KFS84_15260
XCS: KHA79_04600
XHY: FZ025_04605
PRE: PCA10_14730
PFUW: KF707C_41600
PLAL: FXN65_06690
PCQ: PcP3B5_30190(hsaA_2)
PMUI: G4G71_17720
PNT: G5B91_14505
PPG: PputGB1_2207
PPSL: BJP27_02180
PFUV: NLK61_01390
PPZ: H045_08875 H045_09020
PVR: PverR02_09810
PMUD: NCTC8068_03343(hsaA_3)
PBRE: QDY63_11535
PKC: PKB_2661
PSW: LK03_16020
PPSY: AOC04_11320
PYM: AK972_2155
PUM: HGP31_18345
PSEP: C4K39_4234
PPII: QL104_27535
PSAM: HU731_027010 HU731_027170
PASG: KSS96_11745
PTW: TUM18999_33760
PIZ: LAB08_R20910
PKM: PZ739_16485
PSOA: PSm6_49270
PTRL: OU419_13265
PLAU: I0D68_03630
PSNC: C0058_12645
PSKP: KU43P_20700
PMK: MDS_4199
PDEN: F1C79_05805
PNN: KEM63_12330
PCIA: Q6344_06385
ACB: A1S_1864
ABY: ABAYE1701
ABC: ACICU_01975
ABN: AB57_2198
ABB: ABBFA_01570(hsaA)
ABX: ABK1_2443
ABZ: ABZJ_02156
ABR: ABTJ_01733
ABD: ABTW07_2187
ABH: M3Q_2323
ABAD: ABD1_18860
ABJ: BJAB07104_01764
ABAB: BJAB0715_02121
ABAJ: BJAB0868_02114
ABAZ: P795_7525
ABK: LX00_09995
ABAU: IX87_20780
ABAA: IX88_11495
ABW: BL01_00725
ABAL: ABLAC_27380
ACC: BDGL_001343
ANO: RR32_08530
ALC: OTEC02_08160
ACAL: BUM88_06985 BUM88_10705
ASEI: I8T81_08695
ACD: AOLE_08525
ASOL: BEN76_04970
ADV: DJ533_11640
ARJ: DOM24_03915
AGU: AS4_15380
ADS: FPL17_09150
ABER: BSR55_08050
ATN: FM020_06540
AGYL: FPL18_01520
ACIU: A3K93_14200
ATZ: M5E07_06770
APRL: PY247_12060
ACOI: NQU59_16850
AVIV: LF296_05135
ACIE: KIP84_08075
ACIG: BS636_10895
ALR: DS731_04875
HARO: R50071_47540
MAH: MEALZ_3790
MMAI: sS8_5028
HAK: KO116_00201
HAM: HALO0116
HHH: CLM76_06875
HPRO: LMS44_23090
HABD: OM794_22170
HTT: HZS52_05460
MMW: Mmwyl1_1823
MME: Marme_3620
MATH: THO17_20140
MGEO: CFI10_04615
MSEC: LN244_11550
VMS: LVJ82_03825
RSO: RSp0219(ncnH)
RSE: F504_3657
RPU: CDC45_18710
RNC: GO999_23100
CUPP: CTP10_R73140
BTE: BTH_II0323
BTQ: BTQ_3617
BTJ: BTJ_4653
BTZ: BTL_5441
BTV: BTHA_4762
BTHE: BTN_5111
BTHM: BTRA_5380
BTHA: DR62_5241
BTHL: BG87_5447
BOK: DM82_6331
BOC: BG90_4343
BUR: Bcep18194_B2500
BCM: Bcenmc03_3905
BCH: Bcen2424_3615
BCJ: BCAM0644 BCAM2114
BCEN: DM39_4513 DM39_4924
BCEW: DM40_5613
BCEO: I35_4540 I35_5996
BAM: Bamb_5351
BAC: BamMC406_3521
BMJ: BMULJ_03433 BMULJ_03439
BMU: Bmul_5077 Bmul_5083
BMK: DM80_4253 DM80_4260
BMUL: NP80_3640 NP80_3646
BCED: DM42_4446
BCEP: APZ15_21240
BPYR: ABD05_18650
BCON: NL30_22630
BLAT: WK25_18275
BTEI: WS51_01695 WS51_01725
BSEM: WJ12_23190
BPSL: WS57_10705 WS57_12540
BMEC: WJ16_22210
BSTL: BBJ41_30855
BANN: JFN94_20730
BARI: NLX30_19555
BAEN: L3V59_32915
BSER: R0290_22875
BGL: bglu_2g00910
BGU: KS03_3547
BGF: BC1003_3875 BC1003_3884
BGD: bgla_1g15260
BYI: BYI23_A013760 BYI23_B005930
BUQ: AC233_26785
BUM: AXG89_31775
BURK: DM992_28755
BURT: BTHE68_33260
BURM: GJG85_27385
BXE: Bxe_B2308
BXB: DR64_4640
BGE: BC1002_5124
BPY: Bphyt_2161 Bphyt_6111
BFN: OI25_3707
BCAI: K788_0003940 K788_0005052
PARA: BTO02_06065
PARB: CJU94_31910
PHS: C2L64_07330 C2L64_36230
PTER: C2L65_07065 C2L65_31440
PGP: CUJ91_29450
PCAF: DSC91_002778
PGIS: I6I06_03815
PACS: FAZ98_33420
PEW: KZJ38_25175
PDIO: PDMSB3_0784.1
PSAA: QEN71_07515 QEN71_31130
PLAD: PPGU16_14130(nrgC) PPGU16_74080
PAZZ: PBP221_15240 PBP221_77740
PSPU: NA29_23275
PLG: NCTC10937_03009(hsaA_1)
CABA: SBC2_82010(hsaA_2)
CABK: NK8_36140
BUE: BRPE67_ACDS14180 BRPE67_BCDS08210
TVL: FAZ95_34405
CDN: BN940_15426
VAE: RZE79_32195
HGR: DW355_02155
PBH: AAW51_0755
ATER: MW290_06685
HSE: Hsero_1346(ncnH) Hsero_1489(ncnH)
HSZ: ACP92_06750 ACP92_07480
HRB: Hrubri_1157(ncnH) Hrubri_1339(ncnH)
HHF: E2K99_06605 E2K99_07530
HFR: G5S34_06960 G5S34_08265
HEW: HBDW_12120 HBDW_13850
MALI: EYF70_08040
ETB: N7L95_11695
THK: CCZ27_20550
PLA: Plav_1367
PMOB: HG718_14205
PECT: BN1012_Phect1395
RBS: RHODOSMS8_02734(hsaA)
NEO: CYG48_20570
BJA: bll2063(nrgC)
BJU: BJ6T_77930
BJP: RN69_37830
BRK: CWS35_13215
BOT: CIT37_02690
BARH: WN72_10815
BVZ: BRAD3257_7082(nrgC)
BDG: LPJ38_35760
BSEP: HAP48_0034785
BBAN: J4G43_043620
BBRA: QA636_35845
BCOU: IC761_03435
BXN: I3J27_22460
BROS: QUH67_28870
BRAZ: LRP30_30450
BRAY: ML401_07640
RPB: RPB_3894
MRD: Mrad2831_4780
MIND: mvi_01170(nrgC)
MENS: LOK46_31970
MHEY: H2LOC_002660
MIWA: SS37A_18000(nrgC)
MAAD: AZF01_21495
RBM: TEF_13695
CMB: CSW64_05340
CAUB: AMEJIAPC_00981(hsaA)
CEH: CEW89_04600
CBAK: DA792_16075
SSTL: ABFK29_23720
OCD: FHY55_15890
TGL: HFZ77_09585
TMD: KUV46_10225
HAT: RC74_11685
GFU: KM031_19230
PALW: PSAL_015710(hsaA_1) PSAL_021730(hsaA_2)
PSHQ: F3W81_00940
MANH: LA6_001807(hsaA_1) LA6_005347(hsaA_3)
HNE: HNE_3277
HBC: AEM38_04945
NAR: Saro_3809
NOR: FA702_19525
NDR: HT578_10900
NOL: NSDW_23030
SWI: Swit_0738 Swit_4184 Swit_4295
SPHD: HY78_23005
SPCA: GL174_02835
SPHG: AZE99_11865
SFLA: SPHFLASMR4Y_03250(hsaA)
SPHY: CHN51_10695
BLAS: BSY18_169
BFW: B5J99_09860
PARJ: J4G78_06065
PHAO: HF685_05875
ACOA: RB602_14175
NTD: EGO55_15640
GSP: IGS75_08905
APT: APA01_22070
APW: APA42C_22070
APF: APA03_22070
APU: APA07_22070
APG: APA12_22070
APQ: APA22_22070
APX: APA26_22070
APZ: APA32_22070
APK: APA386B_1067
ASZ: ASN_1346(nrgC) ASN_2584
AACE: A0U92_02665 A0U92_15820
ATO: CIW82_05335
AASC: A4S02_09380
ACEK: FLP30_08760
NGU: QN315_06790
AZL: AZL_a08880
ALI: AZOLI_p10984
ATI: AL072_30315
AHU: A6A40_29870
MSD: MYSTI_01236
MFB: MFUL124B02_06905
MLAN: JY572_20365
PPAK: JY651_32745
SUR: STAUR_7920
AGE: AA314_06014
AVM: JQX13_44055
MBD: MEBOL_006408 MEBOL_006972
CFUS: CYFUS_003905
SCL: sce0600
SCU: SCE1572_04140
CCRO: CMC5_036220(fadE)
PAUU: E8A73_012995
MRM: A7982_07097
SAMY: DB32_001527
HOH: Hoch_6104
GFM: Enr17x_18720(hsaA)
GAW: V144x_08180(hsaA)
GBA: J421_1886
BFD: NCTC4823_00654(hsaA_1)
SCIA: HUG15_01500
NDT: L1999_05650
NNV: QNH39_24725
AIA: AWH56_018090
PBJ: VN24_18670
SPOS: DV702_11125
EUZ: DVS28_a1817
MTU: Rv3094c
MTV: RVBD_3094c
MTC: MT3178
MRA: MRA_3126
MTF: TBFG_13111
MTB: TBMG_00873
MTK: TBSG_00879
MTZ: TBXG_000865
MTG: MRGA327_19035
MTI: MRGA423_19290
MTE: CCDC5079_2851
MTUR: CFBS_3263
MTL: CCDC5180_2814
MTO: MTCTRI2_3157
MTD: UDA_3094c
MTN: ERDMAN_3386
MTUB: MT7199_3127
MTUC: J113_21595
MTUE: J114_16555
MTX: M943_15970
MTUL: TBHG_03024
MTUT: HKBT1_3250
MTUU: HKBT2_3255
MTQ: HKBS1_3261
MBO: BQ2027_MB3121C
MBB: BCG_3119c
MBT: JTY_3114
MBM: BCGMEX_3116c
MBK: K60_032110
MBX: BCGT_2945
MAF: MAF_31010
MMIC: RN08_3409
MCE: MCAN_31201
MCQ: BN44_60611
MCV: BN43_60087
MCX: BN42_41111
MCZ: BN45_60083
MORY: MO_003241
MSA: Mycsm_03956
MUL: MUL_3474
MMI: MMAR_1556
MMAE: MMARE11_14690
MLI: MULP_01687
MPSE: MPSD_42910
MSHO: MSHO_56680
MKN: MKAN_22615
MFJ: MFLOJ_23370
MSTO: MSTO_21420
MSAK: MSAS_27870
MKU: I2456_07795
MLW: MJO58_05545
MPAG: C0J29_03260 C0J29_08835
MGOR: H0P51_07820
MBAI: MB901379_01378(hsaA_1)
MSEO: MSEO_49800
MLJ: MLAC_30410
MSHJ: MSHI_23250
MSPG: F6B93_06370
MOT: LTS72_17650
MPAA: MKK62_24180
MKY: IWGMT90018_16250
MWU: PT015_18275
CGT: cgR_2293
CGS: C624_11710
CGG: C629_11720
CHN: A605_13580
CGY: CGLY_10715
CCJZ: ccrud_12910
CAMG: CAMM_01480
CSUR: N24_2482
CCOE: CETAM_09570(hsaA3)
COK: COCCU_13735(hsaA4)
NFA: NFA_28430
NFR: ERS450000_01246(hsaA_4)
RHA: RHA1_ro02839
ROP: ROP_25640
ROA: Pd630_LPD07002
RPY: Y013_03820
RBY: CEJ39_14460
RAV: AAT18_23085
RRZ: CS378_12830
RHQ: IM25_17665
RKO: JWS14_14955
ROZ: CBI38_04590
RPSK: JWS13_29915
RHOU: KZJ41_24550
RHOW: A4U64_01480
RHOJ: JVH1_22705
RHOS: QWW67_13200
RHOY: QNA09_20360
RHOX: RBB84_07845
RHJS: OYT95_24445
PSOW: ABI214_21140
GOR: KTR9_1756
GOQ: ACH46_11335
GTA: BCM27_09460
GOM: D7316_03262(hsaA_3)
GOS: QAD21_08610
GOJ: GR168_08460
GJI: H1R19_22315
GHN: MVF96_08805
SVL: Strvi_4798
SRC: M271_04310
SMAL: SMALA_7733
SSOI: I1A49_42455
SBH: SBI_09701
SLS: SLINC_7755
SPHV: F9278_44470
SBRO: GQF42_41595
SROI: IAG44_04100
SAOV: G3H79_34610
SSPN: LXH13_37995
SFP: QUY26_04045
SLUO: PS467_02905
SCAJ: O1G22_44200
LRP: MUN76_10955
ARTZ: FCN77_09825
JTR: V3C34_01540
NOCQ: QI633_11660
AEZ: C3E78_16725
NOA: BKM31_25180
NGN: LCN96_21570
AMD: AMED_0843 AMED_1899
AMN: RAM_04305 RAM_09635
AMM: AMES_0841 AMES_1884
AMZ: B737_0842 B737_1885
AOI: AORI_4212
AJA: AJAP_17850
AMQ: AMETH_3582
AMYC: CU254_35900
AMYY: YIM_23125(hsaA3)
APRT: MUY14_32585
AROO: NQK81_44965
ATHM: L1857_18550
ARHD: VSH64_04755 VSH64_46815
AMOG: QRX60_01190 QRX60_07105 QRX60_36230 QRX60_45065
ACOR: LCL61_23415
ACAB: QRX50_41630
ANW: QP939_01320 QP939_08360
AMYD: K1T34_34845
AMYE: MJQ72_07035
AMYS: CVV72_07125
PSDS: K1T35_01070 K1T35_34935
SESP: BN6_64260
SSYI: EKG83_36550
KUT: JJ691_06680
KBR: Q4V65_08340
KPHY: AOZ06_24575
LED: BBK82_46665
PMAD: BAY61_14220
UME: RM788_40800
MCAB: HXZ27_16010 HXZ27_16015
ACTN: L083_8079
AFS: AFR_42250
NHY: JQS43_08645 JQS43_08650
BSOL: FSW04_19010
AYM: YM304_15660
TBH: Tbon_13090
TFLA: O0235_14210
DDR: Deide_1p01570
 » show all
Reference
1  [PMID:15870323]
  Authors
Leveau JH, Lindow SE
  Title
Utilization of the plant hormone indole-3-acetic acid for growth by Pseudomonas putida strain 1290.
  Journal
Appl Environ Microbiol 71:2365-71 (2005)
DOI:10.1128/AEM.71.5.2365-2371.2005
  Sequence
[ppg:PputGB1_2207]
Reference
2  [PMID:23881445]
  Authors
Scott JC, Greenhut IV, Leveau JH
  Title
Functional characterization of the bacterial iac genes for degradation of the plant hormone indole-3-acetic acid.
  Journal
J Chem Ecol 39:942-51 (2013)
DOI:10.1007/s10886-013-0324-x
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.235
IUBMB Enzyme Nomenclature: 1.14.13.235
ExPASy - ENZYME nomenclature database: 1.14.13.235
BRENDA, the Enzyme Database: 1.14.13.235

  All links  
Gene (2690)   
   MGENES (2017)   
   RefGene (673)   
Protein sequence (181)   
   UniProt (8)   
   SWISS-PROT (2)   
   RefSeq(pep) (171)   
DNA sequence (434)   
   RefSeq(nuc) (413)   
   GenBank (11)   
   EMBL (10)   
Protein domain (7)   
   InterPro (7)   
All databases (3312)   

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