Entry |
|
Name |
3-hydroxybenzoate 6-monooxygenase;
3-hydroxybenzoate 6-hydroxylase;
m-hydroxybenzoate 6-hydroxylase;
3-hydroxybenzoic acid-6-hydroxylase
|
Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
|
Sysname |
3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)
|
Reaction(IUBMB) |
3-hydroxybenzoate + NADH + H+ + O2 = 2,5-dihydroxybenzoate + NAD+ + H2O [RN: R02589]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
A flavoprotein (FAD). Acts also on a number of analogues of 3-hydroxybenzoate substituted in the 2, 4, 5 and 6 positions; NADPH can act instead of NADH, but more slowly.
|
History |
EC 1.14.13.24 created 1984
|
Pathway |
ec01120 | Microbial metabolism in diverse environments |
|
Orthology |
K22270 | 3-hydroxybenzoate 6-monooxygenase |
|
Genes |
» show all
|
Reference |
|
Authors |
Groseclose EE, Ribbons DW, Hughes H. |
Title |
3-Hydroxybenzoate 6-hydroxylase from Pseudomonas aeruginosa. |
Journal |
|
Other DBs |
UM-BBD (Biocatalysis/Biodegradation Database): | 1.14.13.24 |
|