Entry |
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Name |
2-hydroxycyclohexanone 2-monooxygenase
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Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
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Sysname |
2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing)
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Reaction(IUBMB) |
2-hydroxycyclohexan-1-one + NADPH + H+ + O2 = 6-hydroxyhexan-6-olide + NADP+ + H2O [RN: R03281]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
The product decomposes spontaneously to 6-oxohexanoic acid (adipic semialdehyde).
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History |
EC 1.14.13.66 created 1978 as EC 1.14.12.6, transferred 1999 to EC 1.14.13.66
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Pathway |
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Reference |
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Authors |
Davey JF, Trudgill PW. |
Title |
The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species. |
Journal |
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Other DBs |
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