Entry |
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Name |
glyceollin synthase;
dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase
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Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
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Sysname |
2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (cyclizing)
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Reaction(IUBMB) |
(1) 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + [reduced NADPH---hemoprotein reductase] + O2 = glyceollin II + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN: R07195];
(2) 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + [reduced NADPH---hemoprotein reductase] + O2 = glyceollin III + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN: R07196];
(3) 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + [reduced NADPH---hemoprotein reductase] + O2 = glyceollin I + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN: R07197]
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Reaction(KEGG) |
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Substrate |
2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan [CPD: C15509];
[reduced NADPH---hemoprotein reductase] [CPD: C03024];
O2 [CPD: C00007];
4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan [CPD: C15510]
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Product |
glyceollin II;
[oxidized NADPH---hemoprotein reductase] [CPD: C03161];
H2O [CPD: C00001];
glyceollin III [CPD: C15511];
glyceollin I
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Comment |
A cytochrome P-450 (heme-thiolate) protein purified from soybean.
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History |
EC 1.14.14.135 created 2004 as EC 1.14.13.85, transferred 2018 to EC 1.14.14.135
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Pathway |
ec01110 | Biosynthesis of secondary metabolites |
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Reference |
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Authors |
Welle R, Grisebach H. |
Title |
Induction of phytoalexin synthesis in soybean: enzymatic cyclization of prenylated pterocarpans to glyceollin isomers. |
Journal |
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Other DBs |
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