KEGG   ENZYME: 1.14.14.17
Entry
EC 1.14.14.17               Enzyme                                 
Name
squalene monooxygenase;
squalene epoxidase;
squalene-2,3-epoxide cyclase;
squalene 2,3-oxidocyclase;
squalene hydroxylase;
squalene oxydocyclase;
squalene-2,3-epoxidase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
squalene,NADPH---hemoprotein:oxygen oxidoreductase (2,3-epoxidizing)
Reaction(IUBMB)
squalene + [reduced NADPH---hemoprotein reductase] + O2 = (3S)-2,3-epoxy-2,3-dihydrosqualene + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R02874]
Reaction(KEGG)
R02874
Substrate
squalene [CPD:C00751];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]
Product
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]
Comment
A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7, lanosterol synthase, was formerly known as squalene oxidocyclase. The electron donor is EC 1.6.2.4, NADPH---hemoprotein reductase [5,7].
History
EC 1.14.14.17 created 1961 as EC 1.99.1.13, transferred 1965 to EC 1.14.1.3, part transferred 1972 to EC 1.14.99.7, transferred 2011 to EC 1.14.13.132, transferred 2015 to EC 1.14.14.17
Pathway
ec00100  Steroid biosynthesis
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00511  squalene monooxygenase
Genes
HSA6713(SQLE)
PTR464383(SQLE)
PPS100976805(SQLE)
GGO101129462(SQLE)
PON100453462(SQLE)
NLE100585992(SQLE)
MCC706764(SQLE)
MCF102118907(SQLE)
CSAB103237411(SQLE)
CATY105598691(SQLE)
PANU101024819(SQLE)
TGE112630089(SQLE)
RRO104662802(SQLE)
RBB108538084(SQLE)
TFN117079024(SQLE)
PTEH111550671(SQLE)
CJC100410163(SQLE)
SBQ101054084(SQLE)
CSYR103261734(SQLE)
MMUR105882727(SQLE)
LCAT123626491 123645008(SQLE)
OGA100943926(SQLE)
MMU20775(Sqle)
MCAL110310474(Sqle)
MPAH110334642(Sqle)
RNO29230(Sqle)
MCOC116082750(Sqle)
MUN110552435(Sqle)
CGE100764834(Sqle)
MAUA101828754(Sqle)
PLEU114694806(Sqle)
MORG121461493(Sqle)
AAMP119822620(Sqle)
NGI103743909(Sqle)
HGL101709317(Sqle)
CPOC100732653(Sqle)
CCAN109688126(Sqle)
DORD105992349(Sqle)
DSP122102333(Sqle)
NCAR124988952
OCU100356021(SQLE)
OPI101531954(SQLE)
TUP102473783(SQLE)
CFA608021(SQLE)
CLUD112662471(SQLE)
VVP112915974(SQLE)
VLG121499171(SQLE)
AML100465589(SQLE)
UMR103661624(SQLE)
UAH113252737(SQLE)
UAR123797709(SQLE)
ELK111146730
LLV125097171
MPUF101685937(SQLE)
ORO101386907(SQLE)
EJU114211101(SQLE)
ZCA113924202(SQLE)
MLX118015202(SQLE)
FCA101086537(SQLE)
PYU121042961(SQLE)
PBG122495802(SQLE)
PTG102948681(SQLE)
PPAD109273158(SQLE)
AJU106986573(SQLE)
HHV120231766(SQLE)
BTA526535(SQLE)
BOM102264644(SQLE)
BIU109568596(SQLE)
BBUB102411716(SQLE)
CHX102187506(SQLE)
OAS100125351(SQLE)
ODA120878917(SQLE)
CCAD122450914(SQLE)
SSC100113409(SQLE)
CFR102518096(SQLE)
CBAI105082932(SQLE)
CDK105096439(SQLE)
VPC102542392(SQLE)
BACU103015244(SQLE)
LVE103088551(SQLE)
OOR101275903(SQLE)
DLE111164434(SQLE)
PCAD102996556(SQLE)
PSIU116742380(SQLE)
ECB100067615(SQLE)
EPZ103555758(SQLE)
EAI106839365(SQLE)
MYB102239947(SQLE)
MYD102766276(SQLE)
MMYO118670987(SQLE)
MLF102420731(SQLE)
MNA107539554(SQLE)
PKL118718421(SQLE)
HAI109383232(SQLE)
DRO112315359(SQLE)
SHON118988668(SQLE)
AJM119064843(SQLE)
PDIC114514691(SQLE)
PHAS123833168(SQLE)
MMF118631492(SQLE)
RFQ117033653(SQLE)
PALE102894920(SQLE)
PGIG120595652(SQLE)
PVP105292551(SQLE)
RAY107521591(SQLE)
MJV108400205(SQLE)
TOD119238151(SQLE)
SARA101556612(SQLE)
LAV100664731(SQLE)
TMU101359006
DNM101421617(SQLE)
MDO100032247(SQLE)
GAS123231957(SQLE)
SHR100918180(SQLE)
PCW110193305(SQLE)
OAA100076751(SQLE)
GGA420335(SQLE)
PCOC116227739(SQLE)
MGP100546703(SQLE)
CJO107310534(SQLE)
NMEL110394194(SQLE)
APLA101802617(SQLE)
ACYG106038503(SQLE)
AFUL116485727(SQLE)
TGU100225604(SQLE)
LSR110476988(SQLE)
SCAN103814522(SQLE)
PMOA120505198(SQLE)
OTC121337483(SQLE)
PRUF121349874(SQLE)
GFR102033103(SQLE)
FAB101806873(SQLE)
PHI102109574(SQLE)
PMAJ107200846(SQLE)
CCAE111925120(SQLE)
CCW104692651(SQLE)
CBRC103623503(SQLE)
ETL114065244(SQLE)
ZAB102074085(SQLE)
FPG101920264(SQLE)
FCH102054050(SQLE)
CLV102090054(SQLE)
EGZ104134437(SQLE)
NNI104017981(SQLE)
PLET104617099(SQLE)
PCRI104024695(SQLE)
ACUN113477107(SQLE)
TALA104365772(SQLE)
PADL103916372(SQLE)
ACHC115340708(SQLE)
HALD104310485(SQLE)
CCRI104161456(SQLE)
CSTI104550899(SQLE)
EHS104504707
CMAC104479388(SQLE)
GSTE104261844(SQLE)
LDI104340528(SQLE)
MNB103770063(SQLE)
OHA104330492(SQLE)
AAM106496303(SQLE)
AROW112972845(SQLE)
NPD112952744(SQLE)
DNE112989163(SQLE)
ASN102368291(SQLE)
AMJ102563308(SQLE)
CPOO109321952(SQLE)
GGN109305187(SQLE)
PSS102444614(SQLE)
CMY102929627(SQLE)
CPIC101943545(SQLE)
TST117873807(SQLE)
CABI116826537(SQLE)
MRV120399202(SQLE)
ACS100557553(sqle)
PVT110080534(SQLE)
SUND121929845(SQLE)
PBI103062700
PMUR107295853(SQLE)
PGUT117668408(SQLE)
VKO123033690(SQLE)
PMUA114600258(SQLE)
ZVI118089924(SQLE)
GJA107118942(SQLE)
STOW125439014(SQLE)
XLA108695454(sqle.S) 108719421(sqle.L)
XTR100491400(sqle)
NPR108789438(SQLE)
RTEM120941518(SQLE)
BBUF121000908(SQLE)
BGAR122937981(SQLE)
DRE565329(sqleb) 799528(sqlea)
SRX107714342 107719155(sqle)
SANH107666801 107686341
SGH107556968 107592438
CCAR109055982 109056009
CAUA113059233 113115850
PPRM120462296(sqlea)
MAMB125243770(sqlea) 125275704(sqleb)
IPU108256332(sqlea)
PHYP113532934(sqle)
SMEO124375414(sqlea)
TFD113658932(sqlea)
AMEX103022030(sqle)
EEE113577069(sqle)
TRU101073594(sqle)
TNGGSTEN00015617G001
LCO104926267(sqle)
NCC104964943(sqle)
CGOB115021330(sqle)
ELY117266512(sqlea)
EFO125893686(sqlea)
PLEP121945373(sqlea)
SLUC116066669(sqlea)
ECRA117946150(sqlea)
PFLV114557392(sqle)
GAT120810464(sqlea)
PPUG119197864(sqlea)
MSAM119898054(sqlea)
CUD121514036(sqlea)
ALAT119006824(sqlea)
MZE101469229(sqle)
ONL100703372(sqle)
OAU116320637(sqlea)
OLA101165835(sqle)
OML112144081(sqlea)
XMA102218921(sqle)
XCO114143874(sqle)
XHE116714625(sqle)
PRET103478205(sqle)
PFOR103137007(sqle)
PLAI106962779(sqle)
PMEI106924619(sqle)
GAF122831166(sqlea)
CVG107090131(sqle)
CTUL119771395(sqlea)
GMU124864134(sqlea)
NFU107378852(sqle)
KMR108234140(sqlea)
ALIM106523620(sqle)
NWH119410230(sqlea)
AOCE111562938(sqle)
MCEP125016931(sqlea)
CSEM103388631(sqle)
POV109631985(sqle)
SSEN122772048 122774583(sqlea)
HHIP117777255(sqlea)
HSP118113113(sqlea)
LCF108887154(sqle)
SDU111227759(sqle)
SLAL111658124(sqle)
XGL120784387(sqlea)
HCQ109507068(sqle)
BPEC110171635(sqle)
MALB109966629(sqle)
BSPL114843703(sqlea)
SASA106579093 106605546
OTW112222797 112227598
OMY110485563 110511248
OGO123997899 124006371
ONE115121375 115140935
SALP111958774 112076800
SNH120031445 120048506
CCLU121586050(sqlea)
ELS105019213(sqle)
SFM108940515(sqle)
PKI111844075(sqle)
AANG118216892(sqlea)
PSPA121313129(sqlea)
ARUT117400364(sqlea)
LCM102345671 102353148(SQLE) 102363496 102363771 102364039 102364287
CMK103187848(sqlea)
RTP109919445(sqle)
BFO118410114
BBEL109480954
SPU756574 757019 763532
APLC110978788
SKO100370736
DPXDAPPUDRAFT_71528
LGILOTGIDRAFT_144418
PCAN112573399
BGT106061665
GAE121375040 121391435
HRF124142800
HRJ124275304
OSN115228832
LAK106169642
TADTRIADDRAFT_63342
AQU100632870
ATHAT1G58440(XF1) AT2G22830(SQE2) AT4G37760(SQE3) AT5G24140(SQP2) AT5G24150(SQP1) AT5G24160(SQE6)
ALY9305037 9308163 9310239 9310240 9310241 9316531 9324278
CRB17879593 17881486 17882298 17883036 17889030 17896403
CSAT104702819 104706714 104706715 104706717 104706718 104716345 104720986 104729388 104736426 104736427 104736428 104750186 104751922 104770792 104770795 104772519 104787229
EUSEUTSA_v10000099mg EUTSA_v10004005mg EUTSA_v10005661mg EUTSA_v10023406mg
BRP103838611 103842601 103854873 103854874 103854876 103857940 103863546 103864397 103865842 103874288 103874805
BNA106348279 106348280 106366016 106366592 106366599 106380094 106380096 106392124 106392394 106404399 106404411 106404424 106414035 106415877 106426846 106426862 106428446 106432517 106445755 106446452 111197704 111200936 111208640 111211195 111214187
BOE106303240 106307047 106314195 106318641 106321215 106323003 106325308 106339788 106342659
RSZ108811538 108817963 108818016 108823405 108825489 108834520 108836798 108837227 108849546 108850221 108852195 108855833
THJ104798890 104798908 104798909 104801658 104807642 104822879 104823679 104823760
CPAP110807845 110809071
CIT102610049 102614721 102615022 102616721 102622002 102622201 102624111 102624867
CICCICLE_v10000839mg CICLE_v10010276mg CICLE_v10010419mg CICLE_v10010705mg CICLE_v10010782mg CICLE_v10025367mg CICLE_v10029886mg CICLE_v10029969mg
PVY116106813 116109253 116109258 116109277 116109282 116122734 116122735 116122737 116131545 116133721
MINC123202343 123203376 123221443 123225816 123226912 123228678
TCC108660985 18591923 18607297 18607298 18607299 18611338 18611827 18611834
GRA105769380 105772828 105778884 105778885 105778886 105778887 105784925 105785232 105787701 105795485
GHI107898505 107898506 107898507 107898509 107898510 107898512 107905167 107908577 107916766 107930592 107934884 107934890 107934901 107934916 107934957 107935261 107938317 107938857 107950526 107957887
GAB108450247 108457979 108458975 108459422 108459602 108460811 108460812 108469738 108474966 108480717 108486331
DZI111279674 111281465 111282914 111292612 111298163 111298772 111300707 111308631 111312522 111314901
EGR104418420 104419813 104423240 104447805 104449232
GMX100795027 100795522 100796946 100800329 100804406 100808856 100810547 100820031
GSJ114374663 114385447 114385686 114393911 114397505 114414794 114419444 114421346
PVUPHAVU_001G031600g PHAVU_002G216900g PHAVU_006G029400g PHAVU_006G197900g PHAVU_009G074500g
VRA106753043 106765138 106765593 106766844 106774500
VAR108331915 108338681 108342749 108342876 108344729
VUN114164844 114175615 114188185 114188948 114194766
CCAJ109791859 109796770 109808246 109811675 109811686
APRC113847564 113848935 113857491 113858000 113864681
MTRMTR_1g017270 MTR_3g103510 MTR_4g092640 MTR_5g030880 MTR_6g034955 MTR_6g035065
CAM101491995 101493207 101496784 101508894
LJALj0g3v0267429.1(Lj0g3v0267429.1) Lj0g3v0267429.2(Lj0g3v0267429.2) Lj0g3v0267429.3(Lj0g3v0267429.3) Lj0g3v0292939.1(Lj0g3v0292939.1) Lj0g3v0298799.2(Lj0g3v0298799.2) Lj1g3v1779010.1(Lj1g3v1779010.1) Lj1g3v1779010.2(Lj1g3v1779010.2) Lj4g3v0412640.1(Lj4g3v0412640.1) Lj5g3v0347610.1(Lj5g3v0347610.1) Lj6g3v2171780.1(Lj6g3v2171780.1) Lj6g3v2171780.2(Lj6g3v2171780.2) Lj6g3v2171780.3(Lj6g3v2171780.3)
ADU107468743 107480542 107482392 107495824
AIP107605573 107624122 107626262 107638248
AHF112697714 112714750 112728665 112740944 112756004 112785023 112791341 112795667
LANG109332966 109337353 109345643 109358525
FVE101296607 101297207 101301827 101311715 101312297 101312586 101313166 101313461
RCN112169211 112172133 112172174 112172593 112173431 112174075 112174507 112175399 112183737 112192799 112192807 112197445 112199387 112199392 112200311 112200467
PPER18766762 18767485 18768153 18775060 18793889
PMUM103320605 103334961 103334962 103336172
PAVI110745624 110747303 110757217 110757254
PDUL117615124 117631045 117636805 117637083
MDM103404994 103409320 103420059 103420510 103420543 103428431 103431165 103436286 103436299 103438574 103438709 103441409 103443090 103445174 103455855
PXB103931412 103931590 103946237 103946238 103951565 103952120 103952121 103952123 103952682 103967038 103967039 103967055 103967056 103967075
ZJU107420604 107425040 107427421 107427466 107427482 112492770
MNT112094087 112095292 21385790 21396175
CSV101204949 101210582 101213038
CMO103487810 103493632 103495674
BHJ120076479 120077762 120087280
MCHA111004801 111010224 111017664 111025080
CMAX111471032 111481205 111491959 111496410
CMOS111442598 111446533 111454180 111454931 111462746
CPEP111788153 111797580 111805616 111811375
RCU8265245 8267674 8268892 8272164 8281344
JCU105630804(SQE) 105634515 105634535 105634536 105634540 105634542 105634543 105639884
HBR110633570 110635155 110635156 110635160 110635163 110642235 110643574 110647259 110652051 110661905 110661906 110665457 110666477 110669811
MESC110606759 110615992 110618809 110624242 110624578 110625166 110627423 110628978 122724859 122724879 122724886 122724887 122724888
POP18096264 18105959 18108148 18108779 7465918 7497730
PEU105107839 105114089 105114092 105117255 105117259 105130487
PALZ118028376 118035575 118035773 118040992 118040996 118045758 118050555
JRE108983035 108987866 108989032 109001142 109003433 109013467 109022319 118346317
QSU111985237 111989595 111989596 111990047 111990232 112011091
QLO115960408 115968696 115994670 115994671
TWL119982210 119983278 119983769 119986340 120009540 120011244
VVI100254037 100260031 100262930 100265235 100854014
VRI117907890 117911199 117911200 117917303
SLY101250012 101252376(bc2.1) 112940012 112940619
SPEN107011971 107011974 107017670
SOT102579136 102585235
SSTN125847696 125854349
CANN107840150 107851009 107858627 107867273
NTA107761131 107771747 107786596 107821041 107828762 107831617
NSY104211864 104224029 104232898
NTO104103362 104113280 104115212
NAU109210468 109239474
INI109161287 109170294 109171408 109177866
ITR115999778 116022254 116028770 116029673
SIND105159079 105162196 105169793 105172646
OEU111365439 111365440 111376794 111380881 111388896 111390117 111401374 111410179 111410519
EGT105956088 105961564
SSPL121742421 121743295 121761048 121762523 121762922 121765536 121766152 121810949
HAN110883742 110885327 110903826 110912718 110936879 110940251
ECAD122586576 122590852 122595218 122602792
LSV111879628 111900225 111911464 111913279
CCAV112506522 112506592 112514431 112516273 112516564 112519150
DCR108196765 108199283 108202809 108214582 108219323
CSIN114259457 114284236 114298578 114298887 114300785 114323318
BVG104894986 104901642
SOE110803651 110803950
CQI110682470 110685768 110719994 110732064
NNU104591228 104609137
MING122070260
TSS122660088 122661958
PSOM113283435 113286643 113288492 113356619
NCOL116252420 116265744
OSA4332152 4332153
DOSAOs03t0231700-01(Os03g0231700) Os03t0231800-02(Os03g0231800)
OBR102712971 102713249
BDI100839945
ATS109744486
TDC119285011 119291116
TAES123085101 123092891 123098170
TUA125552432
SBI8056854
ZMA100274333 100285558
SITA101777295
SVS117838753
PVIR120646775 120689530
PHAI112874853
PDA103707523 103713674
EGU105055883 105061253
MUS103978791 103993815 103993817 103994329 103994331 103999437
DCT110095241 110115472
PEQ110023856 110023857 110039210
AOF109833188 109834286 109844344
ATR18446877
SMOSELMODRAFT_150266 SELMODRAFT_176270
PPP112296106
CRECHLRE_17g734644v5
VCNVOLCADRAFT_74714
MNGMNEG_6310
CSLCOCSUDRAFT_53930
CVRCHLNCDRAFT_137251
APROF751_4796
OLUOSTLU_88065
OTAOT_ostta08g03180
BPGBathy01g06810
MISMICPUN_60873
MPPMICPUCDRAFT_49604
CMECYME_CMH256C
GSLGasu_30550
SCEYGR175C(ERG1)
SEUBDI49_2141
SPAOSPAR_G03900
AGOAGOS_AAL141C
ERCEcym_6016
KLAKLLA0_F15224g
KMXKLMA_30204(ERG1)
LTHKLTH0B03784g
VPOKpol_2002p90
ZROZYRO0B10912g
CGRCAGL0D05940g
NCSNCAS_0A06930(NCAS0A06930)
NDINDAI_0D01990(NDAI0D01990)
TPFTPHA_0E03160(TPHA0E03160)
TBLTBLA_0C05980(TBLA0C05980) TBLA_0H02130(TBLA0H02130)
TDLTDEL_0E04440(TDEL0E04440)
TGBHG536_0E04540
KAFKAFR_0D01720(KAFR0D01720)
KNGKNAG_0H02660(KNAG0H02660)
ZMKHG535_0C05190
PPAPAS_chr3_0124
DHADEHA2G14300g
PICPICST_75910(ERG1)
PGUPGUG_04402
SPAASPAPADRAFT_62808(ERG1)
LELLELG_00710
CALCAALFM_C108590CA(ERG1)
CTPCTRG_05483
COTCORT_0A09800
CDUCD36_08100
CTENCANTEDRAFT_93607
YLIYALI0E15730g
CLUCLUG_01944
CLUSA9F13_02g03509
CAURCJI97_000262
PKZC5L36_0C07670
BNNFOA43_003086
BBRXBRETT_003315
OPAHPODL_02301
SLUDSCDLUD_004479
NCRNCU08280
NTENEUTE1DRAFT116406(NEUTE1DRAFT_116406)
SMPSMAC_00934
PANPODANSg7130
TTTTHITE_165536 THITE_2115532
MTMMYCTH_2299088
CTHRCTHT_0018980 CTHT_0032780
MGRMGG_06139
PPEIPpBr36_02970
TMNUCRPA7_7904
SSCKSPSK_03260
FGRFGSG_06215
FPUFPSE_02575
FVRFVEG_06181
FOXFOXG_08495
NHENECHADRAFT_34081
TRETRIREDRAFT_121230
TRRM419DRAFT_109136
MAWMAC_01304
MAJMAA_06325
CMTCCM_07184
PLJVFPFJ_06332
VALVDBG_01618
VDAVDAG_01934
CFJCFIO01_07855
CHIGCH63R_04644
SAPOSAPIO_CDS8059
ELAUCREL1_10241
PFYPFICI_04283
SSLSS1G_13084
BFUBCIN_01g00360(Bcerg1)
MBEMBM_00629
PSCOLY89DRAFT_598274 LY89DRAFT_703032 LY89DRAFT_720744
GLZGLAREA_08350
AFMAFUA_5G07780
ACTACLA_012730
NFINFIA_079490
AORAO090701000685
ANGANI_1_450034(An03g03770)
AFVAFLA_005205
ALUCAKAW2_50776S(ERG1)
ACHEACHE_21335S(ERG1)
PCSPc22g15550
PDPPDIP_52510
TMFPMAA_037810
TRGTRUGW13939_08216
CIMCIMG_06149
CPWCPC735_027040
UREUREG_04240
PBLPAAG_08773
PBNPADG_02704
ABEARB_06092
TVETRV_00314
AJEHCAG_02957
BGHBDBG_08449
PNOSNOG_12929
PTEPTT_17609
BZECOCCADRAFT_7296
BSCCOCSADRAFT_37658
BORCOCMIDRAFT_96504
AALTCC77DRAFT_1015578
ZTRMYCGRDRAFT_108597(ERG1)
PFJMYCFIDRAFT_203278
FFUCLAFUR5_06476
BCOMBAUCODRAFT_65358
TMLGSTUM_00004857001
SPOSPBC713.12(erg1)
CNECND06110
CNBCNBD0290
CNGCNAG_06829
CGICGB_I0350C
TMSTREMEDRAFT_42427
TASAA1Q1_01672
TVSTRAVEDRAFT_31841
DSQDICSQDRAFT_59311
PCOPHACADRAFT_263119
SHSSTEHIDRAFT_106330
HIRHETIRDRAFT_323724
PSQPUNSTDRAFT_145584
ADLAURDEDRAFT_115335
FMEFOMMEDRAFT_91853
GTRGLOTRDRAFT_128167
LBCLACBIDRAFT_190855
CCICC1G_03119 CC1G_03987
ABPAGABI1DRAFT69774(AGABI1DRAFT_69774)
ABVAGABI2DRAFT205454(AGABI2DRAFT_205454)
PCUBJR316_0007707
MRRMoror_7244
MOREE1B28_001681
SCMSCHCO_02514140(SCHCODRAFT_02514140) SCHCO_02645878(SCHCODRAFT_02645878)
CPUTCONPUDRAFT_160880
SLASERLADRAFT_356400
WSEWALSEDRAFT_39579
WICJ056_000439
UMAUMAG_02398
PFPPFL1_01556
MGLMGL_0127
MRTMRET_1190
MSYMMSY001_0512
PGRPGTG_06567
MLRMELLADRAFT_47732
DDIDDB_G0293584(sqle)
DPPDICPUDRAFT_49927
DFADFA_07098(sqle)
ACANACA1_157860
SPARSPRG_11641
TBRTb11.02.0780
TBGTbgDal_XI3640
TCR509589.20
LMALMJF_13_1620
LIFLINJ_13_1360
LDOLDBPK_131360
LMILMXM_13_1620
LBZLBRM_13_1480
LPANLPMP_131490
NGRNAEGRDRAFT_62881 NAEGRDRAFT_78243
MCAMCA2872
METUGNH96_03485
MAHMEALZ_0767
MBUREQU24_17590
MMAIsS8_2585
MMOBF6R98_20990
MEINmethR_P0929
MISZMishRS11D_32920
MFBMFUL124B02_14120
CCXCOCOR_01775(ubiF)
SURSTAUR_5420
LLUAKJ09_09405
MRMA7982_03039
MCGGL4_3111
SRKFGW37_00300
GOGC1280_23610
GMSSOIL9_22870
FTJFTUN_7823
FTEFluta_3221
CRMK6119_02985
 » show all
Reference
1  [PMID:5918046]
  Authors
Cory EJ, Russey WE, Ortiz de Montellano PR.
  Title
2,3-oxidosqualene, an intermediate in the biological synthesis of sterols from squalene.
  Journal
J Am Chem Soc 88:4750-1 (1966)
DOI:10.1021/ja00972a056
Reference
2  [PMID:13438881]
  Authors
TCHEN TT, BLOCH K.
  Title
On the conversion of squalene to lanosterol in vitro.
  Journal
J Biol Chem 226:921-30 (1957)
Reference
3  [PMID:5918048]
  Authors
Van Tamelen EE, Willett JD, Clayton RB, Lord KE.
  Title
Enzymic conversion of squalene 2,3-oxide to lanosterol and cholesterol.
  Journal
J Am Chem Soc 88:4752-4 (1966)
DOI:10.1021/ja00972a058
Reference
4  [PMID:5438357]
  Authors
Yamamoto S, Bloch K.
  Title
Studies on squalene epoxidase of rat liver.
  Journal
J Biol Chem 245:1670-4 (1970)
Reference
5  [PMID:234459]
  Authors
Ono T, Bloch K
  Title
Solubilization and partial characterization of rat liver squalene epoxidase.
  Journal
J Biol Chem 250:1571-9 (1975)
Reference
6  [PMID:8358382]
  Authors
Satoh T, Horie M, Watanabe H, Tsuchiya Y, Kamei T
  Title
Enzymatic properties of squalene epoxidase from Saccharomyces cerevisiae.
  Journal
Biol Pharm Bull 16:349-52 (1993)
DOI:10.1248/bpb.16.349
Reference
7  [PMID:12467639]
  Authors
Chugh A, Ray A, Gupta JB
  Title
Squalene epoxidase as hypocholesterolemic drug target revisited.
  Journal
Prog Lipid Res 42:37-50 (2003)
DOI:10.1016/S0163-7827(02)00029-2
Reference
8  [PMID:17852349]
  Authors
He F, Zhu Y, He M, Zhang Y
  Title
Molecular cloning and characterization of the gene encoding squalene epoxidase in Panax notoginseng.
  Journal
DNA Seq 19:270-3 (2008)
DOI:10.1080/10425170701575026
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.14.14.17
IUBMB Enzyme Nomenclature: 1.14.14.17
ExPASy - ENZYME nomenclature database: 1.14.14.17
BRENDA, the Enzyme Database: 1.14.14.17
CAS: 9029-62-3

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