KEGG   ENZYME: 1.14.14.34Help
Entry
EC 1.14.14.34               Enzyme                                 

Name
methanesulfonate monooxygenase (FMNH2);
msuD (gene name);
ssuD (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
methanesulfonate,FMNH2:oxygen oxidoreductase
Reaction(IUBMB)
methanesulfonate + FMNH2 + O2 = formaldehyde + FMN + sulfite + H2O [RN:R10206]
Reaction(KEGG)
Substrate
methanesulfonate [CPD:C11145];
FMNH2 [CPD:C01847];
O2 [CPD:C00007]
Product
formaldehyde [CPD:C00067];
FMN [CPD:C00061];
sulfite [CPD:C00094];
H2O [CPD:C00001]
Comment
The enzyme, characterized from Pseudomonas strains, allows the organisms to utilize methanesulfonate as their sulfur source. It acts in combination with a dedicated NADH-dependent FMN reductase (EC 1.5.1.42), which provides it with reduced FMN. cf. EC 1.14.13.111, methanesulfonate monooxygenase (NADH).
History
EC 1.14.14.34 created 2016
Reference
1  [PMID:10049377]
  Authors
Kertesz MA, Schmidt-Larbig K, Wuest T
  Title
A novel reduced flavin mononucleotide-dependent methanesulfonate sulfonatase encoded by the sulfur-regulated msu operon of Pseudomonas aeruginosa.
  Journal
J Bacteriol 181:1464-73 (1999)
  Sequence
Reference
2  [PMID:12835925]
  Authors
Endoh T, Kasuga K, Horinouchi M, Yoshida T, Habe H, Nojiri H, Omori T.
  Title
Characterization and identification of genes essential for dimethyl sulfide utilization in Pseudomonas putida strain DS1.
  Journal
Appl Microbiol Biotechnol 62:83-91 (2003)
DOI:10.1007/s00253-003-1233-7
Other DBs
ExplorEnz - The Enzyme Database: 1.14.14.34
IUBMB Enzyme Nomenclature: 1.14.14.34
ExPASy - ENZYME nomenclature database: 1.14.14.34
BRENDA, the Enzyme Database: 1.14.14.34

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