Entry
Name
dimethylnonatriene synthase;
CYP82G1;
CYP92C5;
DMNT/TMTT homoterpene synthase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
(3S,6E)-nerolidol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Reaction(IUBMB)
(3S,6E)-nerolidol + [reduced NADPH---hemoprotein reductase] + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + [oxidized NADPH---hemoprotein reductase] + but-3-en-2-one + 2 H2O [RN:
R11949 ]
Reaction(KEGG)
Substrate
(3S,6E)-nerolidol [CPD:
C09704 ];
[reduced NADPH---hemoprotein reductase] [CPD:
C03024 ];
O2 [CPD:
C00007 ]
Product
(3E)-4,8-dimethylnona-1,3,7-triene [CPD:
C21795 ];
[oxidized NADPH---hemoprotein reductase] [CPD:
C03161 ];
but-3-en-2-one [CPD:
C20701 ];
H2O [CPD:
C00001 ]
Comment
A cytochrome P-450 (heme-thiolate) protein isolated from the plants Arabidopsis thaliana (thale cress) and Zea mays (maize). It forms this C11 homoterpene in response to herbivore attack. In vitro the enzyme also converts (6E,10E)-geranyllinalool to (3E,7E)-4,8,12-trimethyltrideca-1,3,7,11-tetraene (see EC
1.14.14.58 , trimethyltridecatetraene synthase).
History
EC 1.14.14.59 created 2018
Orthology
K17961 trimethyltridecatetraene/dimethylnonatriene synthase
K22639 trimethyltridecatetraene/dimethylnonatriene synthase
Genes
ALY : 9319644 9319652 9321760
CSAT : 104747068 104766436 104789998
THJ : 104804632 104804634 109115973
CIC : CICLE_v10019706mg CICLE_v10019727mg
PVY : 116135912 116136030 116144236
MINC : 123222524 123223597
GRA : 105761739 105790734 105790744
GHI : 107932909 107954054 121203463
HSYR : 120153860 120182949
EGR : 104425704 104425705 120288763
GMX : 100787489 100791088 100806378
CCAJ : 109791512 109806103
AHF : 112710320 112710323 112776035 112779361
PCIN : 129288948 129299207
PPER : 18766764 18767393 18767463
PMUM : 103334264 103334265
PAVI : 110756978 110756983 110757046
PDUL : 117638622 117638852
MDM : 103422252 103429931 103435751 103435869 103445372 103445375
MSYL : 126585632 126585634 126585840 126585841 126622163 126623317
MESC : 110628908 110629096 122721345
PEU : 105113599 105134628 105134631
PALZ : 118039012 118039013 118039014 118050412 118056052 118056060
JRE : 108996375 109008521 109012810
CILL : 122292470 122293280
CAVE : 132186240 132189406 132189652
QSU : 111990442 111990448 111990449 112028265 136065749 136069295
QLO : 115958569 115958901 115958981 115959009 115962297
SSTN : 125846298 125852472 125870560
CANN : 107863880 107863881
SMIL : 130985094 130985095
HAN : 110870417 110873500 110873504 110873528 110883899
ECAD : 122607368 122607861 122607862 122608056
CCAV : 112518580 112518673
CSIN : 114262550 114265929 114313174
AEW : 130759629 130759660 130759911 130761329 130761428 130761811 130762098 130763026
ATRI : 130827411 130827412
» show all
Taxonomy
Reference
Authors
Lee S, Badieyan S, Bevan DR, Herde M, Gatz C, Tholl D
Title
Herbivore-induced and floral homoterpene volatiles are biosynthesized by a single P450 enzyme (CYP82G1) in Arabidopsis.
Journal
Sequence
Reference
Authors
Richter A, Schaff C, Zhang Z, Lipka AE, Tian F, Kollner TG, Schnee C, Preiss S, Irmisch S, Jander G, Boland W, Gershenzon J, Buckler ES, Degenhardt J
Title
Characterization of Biosynthetic Pathways for the Production of the Volatile Homoterpenes DMNT and TMTT in Zea mays.
Journal
Sequence
Other DBs