KEGG   ENZYME: 1.14.14.59
Entry
EC 1.14.14.59               Enzyme                                 
Name
dimethylnonatriene synthase;
CYP82G1;
CYP92C5;
DMNT/TMTT homoterpene synthase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
(3S,6E)-nerolidol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Reaction(IUBMB)
(3S,6E)-nerolidol + [reduced NADPH---hemoprotein reductase] + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + [oxidized NADPH---hemoprotein reductase] + but-3-en-2-one + 2 H2O [RN:R11949]
Reaction(KEGG)
R11949
Substrate
(3S,6E)-nerolidol [CPD:C09704];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]
Product
(3E)-4,8-dimethylnona-1,3,7-triene [CPD:C21795];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
but-3-en-2-one [CPD:C20701];
H2O [CPD:C00001]
Comment
A cytochrome P-450 (heme-thiolate) protein isolated from the plants Arabidopsis thaliana (thale cress) and Zea mays (maize). It forms this C11 homoterpene in response to herbivore attack. In vitro the enzyme also converts (6E,10E)-geranyllinalool to (3E,7E)-4,8,12-trimethyltrideca-1,3,7,11-tetraene (see EC 1.14.14.58, trimethyltridecatetraene synthase).
History
EC 1.14.14.59 created 2018
Orthology
K17961  trimethyltridecatetraene/dimethylnonatriene synthase
K22639  trimethyltridecatetraene/dimethylnonatriene synthase
Genes
ATHAT3G25180(CYP82G1)
ALY9319644 9319652 9321760
CRB17893119
CSAT104747068 104766436 104789998
EUSEUTSA_v10002489mg
BRP103860272
BNA106361807 106447410 111204589
BOE106331605
RSZ108861615
THJ104804632 104804634 109115973
CPAP110823399
CIT102609399 102626017 102626501
CICCICLE_v10019706mg CICLE_v10019727mg
PVY116135912 116136030 116144236
MINC123222524 123223597
TCC18612710
GRA105761739 105790734 105790744
GHI107932909 107954054 121203463
GAB108485575 108487326
DZI111313487 111314425
EGR104425704 104425705
GMX100787489 100791088 100806378
GSJ114389527 114390167
PVUPHAVU_010G022600g PHAVU_010G022700g
VRA106772971 106773394
VAR108346716 108347157
VUN114166085 114166300
CCAJ109791512 109806103
APRC113849582
MTRMTR_8g012585
CAM105852562
LJALj3g3v0718740.1(Lj3g3v0718740.1) Lj3g3v0718760.1(Lj3g3v0718760.1) Lj3g3v0718770.1(Lj3g3v0718770.1)
ADU107464639 107464663
AIP107618159 107618190
AHF112710320 112710323 112776035 112779361
LANG109361544
RCN112168955
PPER18766764 18767393 18767463
PMUM103334264 103334265
PAVI110756978 110756983 110757046
PDUL117638622 117638852
MDM103422252 103429931 103435751 103435869 103445372 103445375
PXB103940018 103961404
ZJU107426783
MNT21384584 21411156
RCU8286091
JCU105644348 105644695
HBR110667432
MESC110628908 110629096 122721345
POP18104574 7494570
PEU105113599 105134628 105134631
PALZ118039012 118039013 118039014 118050412 118056052 118056060
JRE108996375 109008521 109012810
QSU111990442 111990448 111990449 112028265
QLO115958569 115958901 115958981 115959009 115962297
TWL120007177
SLY101246085
SPEN107029603
SOT102585194 102586474
SSTN125846298 125852472 125870560
CANN107863880 107863881
NTA107766114 107799574
NSY104229803
NAU109231518
INI109182929
ITR116025840
SSPL121785522
HAN110870417 110873500 110873504 110873528 110883899
ECAD122607368 122607861 122607862 122608056
LSV111885511 111885523
CCAV112518580 112518673
DCR108213090
CSIN114262550 114265929 114313174 114321719
BVG104908785
SOE110803253
CQI110687786 110703424
MING122094818
SBI8081144
ZMA103631958
SVS117842064
PHAI112879393
 » show all
Reference
1  [PMID:21088219]
  Authors
Lee S, Badieyan S, Bevan DR, Herde M, Gatz C, Tholl D
  Title
Herbivore-induced and floral homoterpene volatiles are biosynthesized by a single P450 enzyme (CYP82G1) in Arabidopsis.
  Journal
Proc Natl Acad Sci U S A 107:21205-10 (2010)
DOI:10.1073/pnas.1009975107
  Sequence
[ath:AT3G25180]
Reference
2  [PMID:27662898]
  Authors
Richter A, Schaff C, Zhang Z, Lipka AE, Tian F, Kollner TG, Schnee C, Preiss S, Irmisch S, Jander G, Boland W, Gershenzon J, Buckler ES, Degenhardt J
  Title
Characterization of Biosynthetic Pathways for the Production of the Volatile Homoterpenes DMNT and TMTT in Zea mays.
  Journal
Plant Cell 28:2651-2665 (2016)
DOI:10.1105/tpc.15.00919
  Sequence
[zma:103631958]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.14.59
IUBMB Enzyme Nomenclature: 1.14.14.59
ExPASy - ENZYME nomenclature database: 1.14.14.59
BRENDA, the Enzyme Database: 1.14.14.59

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