KEGG   ENZYME: 1.14.14.72Help
Entry
EC 1.14.14.72               Enzyme                                 

Name
drimenol monooxygenase;
PhDOX1
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
drimenol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (drimendiol forming)
Reaction(IUBMB)
drimenol + [reduced NADPH---hemoprotein reductase] + O2 = drimendiol + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R12010]
Reaction(KEGG)
Substrate
drimenol [CPD:C19743];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]
Product
drimendiol [CPD:C21843];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]
Comment
A cytochrome P-450 (heme-thiolate) protein isolated from the plant Persicaria hydropiper (water pepper).
History
EC 1.14.14.72 created 2018
Orthology
K22691  drimenol monooxygenase
Reference
1  [PMID:28258968]
  Authors
Henquet MGL, Prota N, van der Hooft JJJ, Varbanova-Herde M, Hulzink RJM, de Vos M, Prins M, de Both MTJ, Franssen MCR, Bouwmeester H, Jongsma M
  Title
Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes.
  Journal
Plant J 90:1052-1063 (2017)
DOI:10.1111/tpj.13527
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.14.14.72
IUBMB Enzyme Nomenclature: 1.14.14.72
ExPASy - ENZYME nomenclature database: 1.14.14.72
BRENDA, the Enzyme Database: 1.14.14.72

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