KEGG   ENZYME: 1.14.19.14Help
Entry
EC 1.14.19.14               Enzyme                                 

Name
linoleoyl-lipid Delta9 conjugase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
BRITE hierarchy
Sysname
linoleoyl-lipid,reduced acceptor:oxygen 8,11-allylic oxidase (8E,10E-forming)
Reaction(IUBMB)
a linoleoyl-[glycerolipid] + reduced acceptor + O2 = an (8E,10E,12Z)-octadeca-8,10,12-trienoyl-[glycerolipid] + acceptor + 2 H2O
Substrate
linoleoyl-[glycerolipid] [CPD:C21529];
reduced acceptor [CPD:C00030];
O2 [CPD:C00007]
Product
(8E,10E,12Z)-octadeca-8,10,12-trienoyl-[glycerolipid];
acceptor [CPD:C00028];
H2O [CPD:C00001]
Comment
The enzyme, characterized from the plant Calendula officinalis, converts a single cis double bond at position 9 of fatty acids incorporated into glycerolipids into two conjugated trans double bonds at positions 8 and 10.
History
EC 1.14.19.14 created 2015
Orthology
K21708  linoleoyl-lipid Delta9 conjugase
Reference
1  [PMID:11161042]
  Authors
Qiu X, Reed DW, Hong H, MacKenzie SL, Covello PS
  Title
Identification and analysis of a gene from Calendula officinalis encoding a fatty acid conjugase.
  Journal
Plant Physiol 125:847-55 (2001)
Reference
2  [PMID:11067856]
  Authors
Cahoon EB, Ripp KG, Hall SE, Kinney AJ
  Title
Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid.
  Journal
J Biol Chem 276:2637-43 (2001)
DOI:10.1074/jbc.M009188200
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.14
IUBMB Enzyme Nomenclature: 1.14.19.14
ExPASy - ENZYME nomenclature database: 1.14.19.14
BRENDA, the Enzyme Database: 1.14.19.14

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