KEGG   ENZYME: 1.14.19.28
Entry
EC 1.14.19.28               Enzyme                                 
Name
sn-1 stearoyl-lipid 9-desaturase;
desC (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
Sysname
1-stearoyl-2-acyl-[glycerolipid],ferredoxin:oxygen oxidoreductase (9,10 cis-dehydrogenating)
Reaction(IUBMB)
a 1-stearoyl-2-acyl-[glycerolipid] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ = a 1-oleoyl-2-acyl-[glycerolipid] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
Substrate
1-stearoyl-2-acyl-[glycerolipid];
reduced ferredoxin [iron-sulfur] cluster [CPD:C00138];
O2 [CPD:C00007];
H+ [CPD:C00080]
Product
1-oleoyl-2-acyl-[glycerolipid];
oxidized ferredoxin [iron-sulfur] cluster [CPD:C00139];
H2O [CPD:C00001]
Comment
The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 9 of stearoyl groups (18:0) attached to the sn-1 position of glycerolipids. The enzyme is nonspecific with respect to the polar head group of the glycerolipid.
History
EC 1.14.19.28 created 2015
Orthology
K23054  sn-1 stearoyl-lipid 9-desaturase
Genes
LAB: LA76x_3785
LAQ: GLA29479_942
LCP: LC55x_3788
LGU: LG3211_1428
LAEG: L2Y94_00175
PFV: Psefu_1593
HJA: BST95_06850
MNR: ACZ75_23535
BEBA: BWI17_00040
AAK: AA2016_5347
RLT: Rleg2_0069
RHN: AMJ98_CH00444
RHX: AMK02_CH00445
REZ: AMJ99_CH00444
RAD: CO657_00350
RHID: FFM81_018930
RBQ: J2J99_02345
RLN: J0663_11120
TRB: HB776_22640
MDI: METDI0702
MCH: Mchl_0732
MPO: Mpop_2228
MZA: B2G69_10360
LABR: CHH27_00670
BRD: JL11_04570
BMED: GYM46_08745
OCD: FHY55_14745
MALU: KU6B_40580(desC3)
SNJ: A7E77_02965
SPAP: H3Z74_01420
SPAI: FPZ24_07960
SPHY: CHN51_01825
SPHS: ETR14_04680
CCX: COCOR_04747
MFU: LILAB_00410
MMAS: MYMAC_001780
SCL: sce0690
MRM: A7982_01170
SAMY: DB32_004490
NANN: O0S08_17565
BEX: A11Q_2549
HAX: BALOs_0899
SBF: JCM31447_01880
PIJ: QEJ31_08215
MKN: MKAN_26240
NFA: NFA_22050
NFR: ERS450000_01893
AMN: RAM_28475
AMM: AMES_5512
AMZ: B737_5512
BSOL: FSW04_08395
SYN: sll0541(desC(des9))
SYZ: MYO_125630(desC(des9))
SYY: SYNGTS_2538(desC)
SYT: SYNGTI_2537(desC)
SYS: SYNPCCN_2536(desC)
SYQ: SYNPCCP_2536(desC)
SYJ: D082_16540(desC)
SYO: C7I86_13285
SYC: syc1549_d(desC)
SYU: M744_03400
SYF: Synpcc7942_2561
SYD: Syncc9605_2541
SYE: Syncc9902_2191 Syncc9902_2192
SYG: sync_2791 sync_2793
SYR: SynRCC307_2393 SynRCC307_2395
SYX: SynWH7803_2415(desC) SynWH7803_2417(desC)
SYP: SYNPCC7002_A2198(desC)
SYNE: Syn6312_0622 Syn6312_1743
SYNK: KR100_15525
SYNR: KR49_08200
SYND: KR52_03225
SYH: Syncc8109_2618(desC)
SYNW: SynWH8103_02736
SYV: AWQ23_10980
SYL: AWQ21_11125
SYNC: CB0101_00320 CB0101_07525 CB0101_07535
SYNY: BM449_04770 BM449_04780
DSL: Dacsa_0829
SYW: SYNW2377(desC)
CGC: Cyagr_2709 Cyagr_2711
CYI: CBM981_2126
PMA: Pro_1833(OLE1)
PMM: PMM1672(des9)
PMT: PMT_2172 PMT_2174
PMN: PMN2A_1271
PMI: PMT9312_1764
PMB: A9601_18811(ole1)
PMC: P9515_18621(ole1)
PMF: P9303_28931 P9303_28951(ole1)
PMG: P9301_18621(ole1)
PMH: P9215_19451(ole1)
PMJ: P9211_17991(ole1)
PME: NATL1_21421(ole1)
PRC: EW14_2040
PRM: EW15_2227
CMP: Cha6605_5134
AMR: AM1_1527
WNA: KA717_26905
TSZ: OOK60_14860
TVN: NIES2134_107740(desC1) NIES2134_115680(desC2)
SLW: BRW62_06125 BRW62_12340
TEL: tlr1653(desC2) tlr2380(desC1)
THN: NK55_04900(desC2) NK55_11555(desC)
THEC: FFX45_01530 FFX45_05765
LEP: Lepto7376_2492
LEN: LEP3755_06760
LET: O77CONTIG1_03274 O77CONTIG1_03680
LBO: LBWT_2260 LBWT_42500
KOV: K9N68_01010
LSC: KIK02_08760
LSK: J5X98_20855
HHG: XM38_043120
THEU: HPC62_15085 HPC62_17785
TSIN: OXH18_19075 OXH18_19080
GLP: Glo7428_0047
GEN: GM3709_1645
GEE: GM3708_530
CHON: NIES4102_12720(desC)
MAR: MAE_50330(desC)
MPK: VL20_2979
MIQ: B5D77_11225
MVZ: myaer102_23510(desC)
CAN: Cyan10605_0014
CSN: Cyast_0516
CYL: AA637_05810(desC)
HAO: PCC7418_1242
ENN: FRE64_04400
CYU: UCYN_05530
CYT: cce_3100(desC1)
CWA: CwatDRAFT_1377
CYP: PCC8801_0640
CYH: Cyan8802_0662
CYC: PCC7424_3349
CYJ: Cyan7822_5588
CYN: Cyan7425_4812
TER: Tery_1437
ARP: NIES39_L02040(desC)
PAGH: NIES204_34440(desC)
PPSU: NO713_03226(ADS3)
OXY: HCG48_25280
MVAG: D0A34_03095 D0A34_03105
LFS: HFV01_07745
MIC: Mic7113_1889
GEI: GEI7407_0446
OAC: Oscil6304_5631
ONI: Osc7112_3803 Osc7112_3804
MPRO: BJP34_22970
PHOR: JWS08_21245
PYH: NEA10_10950
CEP: Cri9333_0221
GVI: glr1235(desC)
GLJ: GKIL_3522(desC)
GML: ISF26_05595
ANA: all1599(desC)
NPU: Npun_R6232
NOS: Nos7107_0618
NOP: Nos7524_4756
NON: NOS3756_14550
NFL: COO91_07296
NOE: CLI64_08225
NSH: GXM_01593
NED: HUN01_29395
AVA: Ava_4212
NAZ: Aazo_3554
ANB: ANA_C20202
ACY: Anacy_4776
AWA: AA650_16770
ANN: EH233_10965
CSG: Cylst_2676
RSIN: B6N60_02677
HBQ: QI031_00950
CALO: Cal7507_2593
CALT: Cal6303_1443
CALH: IJ00_05005
CALN: NIES2098_27900
RIV: Riv7116_4397 Riv7116_5894
FIS: FIS3754_37630
NSPH: BDGGKGIB_02541
DOU: BMF77_00179
DFS: HGD76_17205
DHT: NG743_21970
CCUR: IAR63_05425
CRK: L3I90_06320
AFLO: HEQ12_18915
TOQ: HCG51_19365
NCN: BZZ01_14795 BZZ01_18245
CTHE: Chro_4139
PLP: Ple7327_0060 Ple7327_0061
SCS: Sta7437_3027
STAN: STA3757_26310(desC)
GCY: LQF76_11620
CEO: ETSB_1681(desC)
CER: RGRSB_1326(desC)
ROL: CA51_19930
AAGG: ETAA8_48240
BVO: Pan97_23020
RLC: K227x_15260 K227x_24310 K227x_57240
PBS: Plabr_0643 Plabr_4622
SDYN: Mal52_04350
SACI: Sinac_3004
PBOR: BSF38_00549
AGV: OJF2_65440
PHM: PSMK_25950
PCOR: KS4_06540
ABA: Acid345_4171
ACM: AciX9_1688
GRW: FTO74_12200
TSA: AciPR4_2160 AciPR4_2410
TRS: Terro_0105
TALB: FTW19_22055
ABAS: ACPOL_1636 ACPOL_5501
ADIN: H7849_02630 H7849_23410
ABAC: LuPra_01032
MCOS: GM418_06960
CHIH: GWR21_03985
FGG: FSB75_04860
AGI: FSB73_10810
ARAC: E0W69_013520
FLN: FLA_5482
SHG: Sph21_4486
SPHN: BV902_21835
SPDR: G6053_08660
STHA: NCTC11429_00217
MUC: MuYL_3330
MUH: HYN43_005540 HYN43_007955
MGIN: FRZ54_16340
MGK: FSB76_02760
MRUB: DEO27_005735
MGOS: DIU38_005555
MMAB: HQ865_12340
MGIK: GO620_007170
MDJ: LLH06_09345
OLI: FKG96_20355
DCN: MUK70_15775
HSW: Hsw_2919
FEK: C1H87_16940
MGEL: G5B37_12475
NLI: G3M70_17875
NWT: NSPWAT_1991
 » show all
Reference
1  [PMID:8419301]
  Authors
Wada H, Schmidt H, Heinz E, Murata N
  Title
In vitro ferredoxin-dependent desaturation of fatty acids in cyanobacterial thylakoid membranes.
  Journal
J Bacteriol 175:544-7 (1993)
DOI:10.1128/JB.175.2.544-547.1993
Reference
2  [PMID:12231903]
  Authors
Higashi S, Murata N
  Title
An in Vivo Study of Substrate Specificities of Acyl-Lipid Desaturases and Acyltransferases in Lipid Synthesis in Synechocystis PCC6803.
  Journal
Plant Physiol 102:1275-1278 (1993)
DOI:10.1104/pp.102.4.1275
Reference
3  [PMID:7929259]
  Authors
Sakamoto T, Wada H, Nishida I, Ohmori M, Murata N
  Title
delta 9 Acyl-lipid desaturases of cyanobacteria. Molecular cloning and substrate specificities in terms of fatty acids, sn-positions, and polar head groups.
  Journal
J Biol Chem 269:25576-80 (1994)
  Sequence
[syn:sll0541] [ana:all1599]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.28
IUBMB Enzyme Nomenclature: 1.14.19.28
ExPASy - ENZYME nomenclature database: 1.14.19.28
BRENDA, the Enzyme Database: 1.14.19.28

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Gene (3212)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (272)   
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