KEGG   ENZYME: 1.14.99.21Help
Entry
EC 1.14.99.21               Enzyme                                 

Name
Latia-luciferin monooxygenase (demethylating);
luciferase (Latia luciferin);
Latia luciferin monooxygenase (demethylating)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
BRITE hierarchy
Sysname
Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)
Reaction(IUBMB)
Latia luciferin + reduced acceptor + 2 O2 = oxidized Latia luciferin + CO2 + formate + acceptor + H2O + hnu [RN:R03907]
Reaction(KEGG)
Substrate
Latia luciferin [CPD:C02293];
reduced acceptor [CPD:C00030];
O2 [CPD:C00007]
Product
oxidized Latia luciferin [CPD:C03527];
CO2 [CPD:C00011];
formate [CPD:C00058];
acceptor [CPD:C00028];
H2O [CPD:C00001];
hnu [CPD:C00205]
Comment
A flavoprotein. Latia is a bioluminescent mollusc. The reaction possibly involves two enzymes, an oxygenase followed by a monooxygenase for the actual light-emitting step.
History
EC 1.14.99.21 created 1976, modified 1982
Reference
1  [PMID:5650377]
  Authors
Shimomura O, Johnson FH.
  Title
The structure of Latia luciferin.
  Journal
Biochemistry 7:1734-8 (1968)
Reference
2  [PMID:4506078]
  Authors
Shimomura O, Johnson FH, Kohama Y.
  Title
Reactions involved in bioluminescence systems of limpet (Latia neritoides) and luminous bacteria.
  Journal
Proc Natl Acad Sci U S A 69:2086-9 (1972)
DOI:10.1073/pnas.69.8.2086
Other DBs
ExplorEnz - The Enzyme Database: 1.14.99.21
IUBMB Enzyme Nomenclature: 1.14.99.21
ExPASy - ENZYME nomenclature database: 1.14.99.21
BRENDA, the Enzyme Database: 1.14.99.21
CAS: 62213-54-1

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