KEGG   ENZYME: 1.14.99.35
Entry
EC 1.14.99.35               Enzyme                                 
Name
thiophene-2-carbonyl-CoA monooxygenase;
thiophene-2-carboxyl-CoA dehydrogenase;
thiophene-2-carboxyl-CoA hydroxylase;
thiophene-2-carboxyl-CoA monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
Sysname
thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase
Reaction(IUBMB)
thiophene-2-carbonyl-CoA + reduced acceptor + O2 = 5-hydroxythiophene-2-carbonyl-CoA + acceptor + H2O [RN:R05742]
Reaction(KEGG)
R05742
Substrate
thiophene-2-carbonyl-CoA [CPD:C07347];
reduced acceptor [CPD:C00030];
O2 [CPD:C00007]
Product
5-hydroxythiophene-2-carbonyl-CoA [CPD:C07348];
acceptor [CPD:C00028];
H2O [CPD:C00001]
Comment
A molybdenum enzyme. Highly specific for thiophene-2-carbonyl-CoA. Tetrazolium salts can act as electron acceptors.
History
EC 1.14.99.35 created 2000
Reference
1  [PMID:9531630]
  Authors
Bambauer A, Rainey FA, Stackebrandt E, Winter J.
  Title
Characterization of Aquamicrobium defluvii gen. nov. sp. nov., a thiophene-2-carboxylate-metabolizing bacterium from activated sludge.
  Journal
Arch Microbiol 169:293-302 (1998)
DOI:10.1007/s002030050575
Other DBs
ExplorEnz - The Enzyme Database: 1.14.99.35
IUBMB Enzyme Nomenclature: 1.14.99.35
ExPASy - ENZYME nomenclature database: 1.14.99.35
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.99.35
BRENDA, the Enzyme Database: 1.14.99.35
CAS: 208540-44-7

  All links  
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (3)   

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