KEGG   ENZYME: 1.15.1.2
Entry
EC 1.15.1.2                 Enzyme                                 
Name
superoxide reductase;
neelaredoxin;
desulfoferrodoxin
Class
Oxidoreductases;
Acting on superoxide as acceptor;
Acting on superoxide as acceptor (only sub-subclass identified to date)
Sysname
rubredoxin:superoxide oxidoreductase
Reaction(IUBMB)
superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin [RN:R05743]
Reaction(KEGG)
R05743
Substrate
superoxide [CPD:C00704];
reduced rubredoxin [CPD:C00340];
H+ [CPD:C00080]
Product
H2O2 [CPD:C00027];
oxidized rubredoxin [CPD:C00435]
Comment
The enzyme contains non-heme iron.
History
EC 1.15.1.2 created 2001 as EC 1.18.96.1, transferred 2001 to EC 1.15.1.2
Orthology
K05919  superoxide reductase
Genes
EALEAKF1_ch3412c
CFDCFNIH1_13140
METYMRY16398_12390(rbo)
KINAB182_05565
PDZHHA33_08275
EBCC2U52_15210
SERASer39006_011130
SERQCWC46_11125
DDADd703_1404
BGJAWC36_00140
FBLFbal_1766
MDNJT25_022560
MDHAYM39_07550 AYM39_13650
MKOMKLM6_1550 MKLM6_2799
METLU737_11160
MPADKEF85_12540
MPSYCEK71_04805
MESLKKZ03_07735 KKZ03_07955
TIGTHII_0066
HNAHneap_2226
KAKKalk_10020
OMEOLMES_3841
TDNSuden_0990
SUASaut_1297
SULNFJR47_04310
SULGFJR48_05345
SULCCVO_05270
SPALFM071_04375
SSEIFJR45_05585
SBALHUE88_06965
SMASHUE87_05775
SKUSulku_1367
SULRB649_06470
CSPFCSF_1368
CBLACBLAS_1215
SDLSdel_1185
SBASulba_1078 Sulba_1286
SMULSMUL_1334 SMUL_1620
SHALSHALO_1315 SHALO_1578
SULSSdiek1_0483 Sdiek1_1387
SULJSJPD1_0488 SJPD1_1320
SULTFA592_09470 FA592_12860
AELLAELL_0887
AAQIAAQM_0781
ASUIASUIS_0866
ACLOACLO_0854
AVPAVENP_1023
ADZADFLV_0890
ALKALEK_1048
ALPLPB137_04455
AHSAHALO_0847
AMYTAMYT_0948
AMARAMRN_0910
ACAAACAN_0960
AMOLAMOL_0819
APAIAPAC_0773
HBVABIV_0649
HEBRAEBR_0915
AANAAANAER_0900
PACOAACT_0982
ARCABLL_0958
HYONNO_1116
NSANitsa_1499
SUNSUN_1204
SLHYH65_05835
SINUIMZ28_05340 IMZ28_07280
NAMNAMH_0095 NAMH_0448
NAPC3L23_00495 C3L23_02355
CMEDFE773_00510 FE773_03150
CPAFC6V80_00455 C6V80_07575
GSUGSU0720
GSKKN400_0698
GMEGmet_2613
GEMGM21_0956
GEBGM18_3374
GPIGPICK_04345
GAOA2G06_03750
GEFFO488_13170 FO488_18880
GBZJZM60_01355
GURGura_2207 Gura_2513
GEOGeob_3296
GLOGlov_2591
GBMGbem_3292
GBNGEOBRER4_09240(dfx)
GSBGSUB_13600 GSUB_15705
GERKP004_04080
GSUBKP001_07775 KP001_11325
GNTKP003_03875 KP003_10880
PCAPcar_2347
PACEA6070_12915
PEFA7E78_12880
PPDPpro_1133
DESDSOUD_0362 DSOUD_0985
DEUDBW_3006 DBW_3014
DVEDESUT3_08990(dfx)
DVUDVU_3183(rbO)
DVLDvul_0204
DVMDvMF_2481
DVGDeval_2940
DDSDdes_2010
DFIAXF13_11450
DPGDESPIGER_2365
DEFCNY67_02060
DTRRSDT_0359(dfx)
DFLDFE_2921
DSDGD606_04580
DMADMR_17610(rbo)
DCBC3Y92_07990
DGGDGI_3082(nlr)
DDEDde_3193
DMSE8L03_10500
DSADesal_0088 Desal_2678
DHYDESAM_20639(dfx) DESAM_21841
DAFDesaf_3320
DASDaes_0807 Daes_1577
DPIBN4_11664(dfx)
DEJAWY79_05230 AWY79_12210
PPRFDPRO_2575(dfx)
PSELGM415_07595
DDNDND132_0426 DND132_1757
LIPLI0273
LIRLAW_00282
DSXGD604_12830
PBIZLWC08_11065
DBADbac_2514
DRTDret_0140
DPSDP1668
DSFUWK_01501 UWK_03533
DAKDaAHT2_2068
DPRDespr_3311
DEOCAY53_02815
DOGHP555_04105
DBKDGMP_07800(dfx)
DOLDole_2870
DMLDmul_11290(dfx)
DALDalk_2367
DATHRM2_42000(dfx)
DTOTOL2_C17410(dfx)
DOVDSCO28_52640(dfx)
DWDDSCW_20160(dfx_1) DSCW_49810(dfx_2)
DALKDSCA_32000(dfx)
DLIdnl_13990(dfx)
DMMdnm_085620(dfx)
DEKDSLASN_03210
SAMYDB32_001798
DAODesac_2165
DTIDesti_2658 Desti_4277
SFUSfum_3891
DAXFDQ92_05220
DBRDeba_2050
HMRHipma_0419
DAVDESACE_01650
PCAYFRD00_15075
DHRLGS26_01090
MGMMmc1_2950
PBKBack11_08260
CACCA_C2450
CAESMB_G2485
CAYCEA_G2464
CTCCTC_02454
CTETBN906_02692
CBACLB_3391
CBHCLC_3278
CBYCLM_3769
CBLCLK_2750
CBBCLD_1188
CBICLJ_B3615
CBFCLI_3506
CBMCBF_3487
CBJH04402_03416
CBECbei_3348
CBZCbs_3348
CBEILF65_03833
CKLCKL_3781(rbo)
CKRCKR_3342
CCBClocel_4154
CLSCXIVA_06330
CLBClo1100_4093
CSRCspa_c24390(dfx) Cspa_c24400
CPASClopa_1192
CPATCLPA_c12400(dfx)
CPAECPAST_c12400(dfx)
CSBCLSA_c38480(dfx)
CSQCSCA_4512
CLDCLSPO_c34560(dfx)
CACECACET_c37570
CCKCcar_10905 Ccar_17895 Ccar_18940
CBUTATN24_17965
CTYKCTK_C26860(dfx)
CEUA7L45_19730
CFMBJL90_04515
CARGRSJ17_15640
CDRKB9W14_22450
CIABEN51_04400
CDYF3K33_17005
CCOHSAMEA4530647_2158(dfx)
CFERD4Z93_10020 D4Z93_10995
CGASJ1C67_17960
AMTAmet_4653
AOEClos_0239
HHWNCTC503_00627(dfx)
CALEFDN13_04200
CPRFK7H06_05480
CAZOG3A45_12370
HSCHVS_15645(dfx)
CCECcel_3474
RHEREHE19_008590
CTHDCDO33_11570
FPLAA4U99_10100
EHAEthha_2703
RUMCK1_08610
FPRFP2_03800 FP2_17640
FPAFPR_06860 FPR_07330
CAPREQM14_11165
OVAOBV_40810(rbo)
OBJEIO64_07045
CAMLH6X83_02100
SMANC12CBH8_04820
VFAMM35RIKEN_14000(rbo) MM35RIKEN_23700(rbo)
VCOPMM50RIKEN_15760(rbo)
CFEMHCR03_18070
ACOLK5I23_00950 K5I23_14285
BPBbpr_I0377(dfx)
BFICIY_31980
BHUbhn_I1019
CLEClole_2224
CEWEKH84_13780
CEVLK421_11825
ROBCK5_07940
BYLA4V09_15260
BPROPMF13cell1_00460(dfx_1) PMF13cell1_02030(dfx_3)
BLABEYS05_13000
BLIQINP51_02625 INP51_14390
CPYCphy_0987 Cphy_1924
LACYA4V08_05450 A4V08_08100
CSCIHDCHBGLK_01585(dfx_1)
CSHClosa_2525 Closa_4054
CSOCLS_38870
BPRLCL2_05720
ARFAR1Y2_0799
ACACEYQ97_12935
HSDSD1D_0274
CPROCPRO_00250(dfx)
LUAD4A81_00530
EHLEHLA_2655
PXVFXF36_01765
ANRAna3638_08275
ACELacsn021_36620(rbo)
ACHTbsdcttw_08410(rbo)
EELEUBELI_20025
CBOLCGC65_18135 CGC65_20685
DLOK5I24_15550
ERTEUR_17120
CDFCD630_08270(rbo)
PDCCDIF630_00946(dsr)
CDCCD196_0776(rbo)
CDLCDR20291_0757(rbo)
PDFCD630DERM_08270(rbo)
EACEAL2_c12690(dfx)
CSTCLOST_1779
FAAHMPREF0389_00796
ROCHF520_04345
PHXKGNDJEFE_00677(dfx_1)
TEBT8CH_2270
PBQC3V37_01065
SLPSlip_1537
CALKHUE98_04525
SGYSgly_3044
DORDesor_1729 Desor_4470
DAIDesaci_0425 Desaci_2304
DMIDesmer_1680
DEDDHBDCA_p2292
DECDCF50_p2304
DRSDEHRE_04495
DAEDtox_1558 Dtox_2714
TFRBR63_17330
FWADCMF_28430
TJRTherJR_0441
DGIDesgi_3404
ELMELI_3815
EMTCPZ25_009605
ELIMB2M23_07390
AWOAwo_c14750(rbo)
ALKAJ0B03_06270
CMIUB1H56_02530
VGUHYG85_05045
VPYHZI73_06670
IBUIB211_01756c
LASAL9O85_06840
MDVC5Q96_06230
AMIJEQM06_05310
AMICAmi3637_00650
ABUTAmi103574_07825
ETMCE91St48_37640(rbo)
EUUADJ67_07665
BPRMCL3_01260
BPRSCK3_07380 CK3_14460
TTETTE2229
TEXTeth514_0680 Teth514_0907
THXThet_2011 Thet_2245
TPDTeth39_0242 Teth39_0429
TITThit_2145
TMTTmath_2065
TBOThebr_0249 Thebr_0441
TWIThewi_2208 Thewi_2467
TKITKV_c15620 TKV_c22020(dfx)
MTAMoth_1285
MTHOMOTHE_c12680(dfx)
MTHZMOTHA_c13540(dfx)
ADGAdeg_0945
TPZTph_c07660 Tph_c08000(dfx)
CSCCsac_2039
ATEAthe_1492
COBCOB47_1062
CHDCalhy_1244
COWCalow_1271
CKICalkr_1477
CLCCalla_0866
CKNCalkro_1218
CCHAELD05_05955
CDIACaldiYA01_10260
TTMTthe_0254
TTOThethe_00250
TXYThexy_0215
TSHTsac_0814
TNRThena_0137
TACITDSAC_0126
MASMahau_2062
TOCToce_1860
HORHore_05310
HASHalsa_2149
HPKHprae_0238
HALSD7D81_15190
IFNGM661_12325
AARAcear_0994
HHLHalha_0779
KMEH0A61_00072(dfx)
FMAFMG_0046
APRApre_1362
AVGI6H45_02280
AOBI6H46_05320
AMEILV469_07595
PEDING2D1G_1219(sorA)
PHARNCTC13077_00214
PIVNCTC13079_01055
MHAPJFY71_01230
CADCuri_c24050
SPOAEQM13_15035
KPARJL105_10000
SEDZJYG23_06790
VPRVpar_1127
VATB7L28_05570
VRM44547418_01196(nlr)
VDNNCTC11831_00764
VNKVEIT17_07050
MEDMELS_0263 MELS_0460
MHWACT01_02635 ACT01_06395
MEGDKB62_02320
MMAXLCQ47_07600 LCQ47_09370
DPNBCB69_00265
DHODia5BBH33_05460
SSGSelsp_2280
SRISELR_07190(dfx)
SELEADJ74_06550
SELOAXE86_03015
SELTBCS37_08230
MHGMHY_06710
MFUNGXM21_00350
PUFUFO1_1486
PFTJBW_02848
MANAMAMMFC1_02699 MAMMFC1_03328
STEDSPTER_24730
AFNAcfer_1201
AINAcin_1207
PFACPFJ30894_02271(dfx)
EUCEC1_18330
FROAALO17_14180
AARGAargi30884_29570(rbo)
ABSIA9CBEGH2_01700(rbo)
CIUG4D55_12770
ERMEYR00_14115
FITFi14EGH31_27910(rbo)
BULLJOS54_03060
EBMSG0102_06320
LCGL3BBH23_10880
ERBA4V01_15640
TURAT726_08130
TSGHLK68_07435
ETTAZF37_06635
AHKNCTC10172_00138(dfx)
MGJMGM1_1960
MBJKQ51_01851(dfx)
STSUB7R87_17155
CCUCcur_12210
SHIShel_15140
ELEElen_1113
EYYEGYY_10540
EGDGS424_005675
GPAGPA_31640
AEQAEQU_1313
AHATADCFC_10640(rbo)
DDTAAY81_08225
CBACJI75_03720
RTSCE91St31_12180(rbo)
APVApar_0897
PCATPcatena_11360
ATBJ4859_06440
CGOCorgl_1164
CAERCSV91_04425
CSTCLK434_01295
MBFBHV42_00810
DFODform_00385(dfx)
ABAOBEQ56_08100
TTFTHTE_0582
KSTKSMBR1_2244
BROCIPI25_00235 IPI25_14055
BPITBPIT_26780
JETL3J17_07500 L3J17_09870
PBUL21SP3_01534(dfx)
PBPSTSP1_01290(dfx)
PBASSMSP2_00801(dfx)
ALUSSTSP2_01130 STSP2_02686(dfx)
VBCC5Q97_02440
VAIBU251_01930
TPWTPANIC_0823(sorA)
TPPTPASS_0823(rbo)
TPUTPADAL_0823(sorA)
TPHTPChic_0823
TPOTPAMA_0823(sorA)
TPASTPSea814_000823
TPCTPECDC2_0823(sorA)
TPGTPEGAU_0823(sorA)
TPMTPESAMD_0823(sorA)
TPBTPFB_0823(sorA)
TDETDE_1754
TSUTresu_0937
TBETrebr_1174
TPLTPCCA_0823(sorA)
TPEDTPE_0071
SCDSpica_1836
TPKJO40_10935
TPHGFUT81_14290
TPAVHRQ91_09905
TPERIWA51_03765
SSMSpirs_0603
STASTHERM_c02360
STQSpith_0220
SPEREW093_16330
SLRL21SP2_1734
OCKEXM22_10725
SBUSpiBuddy_1683 SpiBuddy_1946
SGPSpiGrapes_0076 SpiGrapes_3009
BHCJFL75_09965
THYDTTHT_1808(dfx) TTHT_1831
EMIEmin_0011
EPOEpro_1202(sor)
ETIRSTT_245(sor)
RSDTGRD_271
FVAFV113G1_01590
FULC4N20_05520
FMOC4N19_03230
FGOC4N16_02115
FNFBSQ88_09945
IPOIlyop_2459
TAITaci_0007
ACOAmico_0399
TLITlie_0048
AMOAnamo_0007
CPORBED41_00030
PPIOCE91St28_00370
PMZHMPREF0659_A5163
PDNHMPREF9137_0756
PITPIN17_A0124
PDTPrede_1296
PFUSADJ77_05550
PJECRM71_00725
PNIJ5A59_06260
PMUFJ4864_04635
PHISJ5A62_07490
PCOILK433_02145
PHERprwr041_23580
RBCBN938_1934
BACCBRDCF_p296(sorA)
MBASALGA_3701
SHYRLA303_07425 LA303_11860
CACICLOAM1366(dfx)
SULSYO3AOP1_1257
SAFSULAZ_1417
PMXPERMA_1906
TTKTST_0336
TAMTheam_0447
DTEDester_0591 Dester_1255
TMATM0658
TMMTmari_0658
TMITHEMA_01375
TMWTHMA_0673
TMQTHMB_0673
TMXTHMC_0673
TPTTpet_0273
TRQTRQ2_0271
TNACTN_1928
TNPTnap_0454
THQT2812B_01370
THZCELL2_01420
THRTRQ7_01385
TLETlet_1498
TTATheth_1582
PHYAJ81_04410
TMETmel_1201
TAFTHA_1590
THPBG95_06810
THERY592_06890
TFEJYK00_02420
FNOFnod_0468
FPEFerpe_0521
FIANA23_02910
OCYOSSY52_13890
PMOPmob_1631
MPZMarpi_0102
MARNLN42_00750
DTNDTL3_1841
KOLKole_2139
KPFIX53_01800
MPGTheba_1078
MINFMESINF_2603
ASACATHSA_0174
CPOCOPRO5265_1214
CEXCSE_12390(dfx) CSE_12400
DINSelin_1347
DDFDEFDS_1019
DAPDacet_0863
GTLEP073_10090
CNICalni_1945
FSIFlexsi_0522
CABYCabys_2172
DTHDICTH_0314
DTUDtur_0429
DTPJZK55_19300(dfx)
TIDThein_2055
TOPTOPB45_0541
TCMHL41_05945
THETF1847_00960
CTHITHC_1396
TAVG4V39_02435 G4V39_02440
TMAIFVE67_06950 FVE67_08370
ALAMRT761_01020(nlr)
BANABARAN1_1226(sorA)
BIHBIP78_1275
MJAMJ_0741
MVUMetvu_0440
MFSMFS40622_1434
MIFMetin_0884
MJHJH146_1169
MESGMLAUSG7_0229
MESAMLASG1_1446
MIGMetig_0425
MMPMMP1157(rbo)
MMQMmarC5_0430
MMXMmarC6_1514
MMZMmarC7_0405
MMDGYY_06630
MMAKMMKA1_13350(dfx)
MMAOMMOS7_12650(dfx)
MMADMMJJ_16880(dfx)
MAEMaeo_0331
MVNMevan_0477
MVOMvol_0775
MOKMetok_1598
METFCFE53_02245
MMGMTBMA_c11510(rbo)
METCMTCT_0676
MWOMWSIV6_1130
METEtca_00724(dfx)
METZMETMT2_0612
METKFVF72_07765
MTHMFZP57_05365
METJFZP68_00840
MSTMsp_0788(rbo)
METBAW729_03340
MRUmru_1564(dfx)
MSIMsm_0262
MEBAbm4_1180(dfx)
MMILsm9_0800(dfx)
MEYETL18_06305
MOLYLM1_1050
MELMetbo_0935
MEWMSWAN_1311
METHMBMB1_0845(rbo)
MFCBRM9_1007(dfx)
MFIDSM1535_1665(rbo)
MCUBMCBB_1262(dfx)
MSUBBK009_04445
METNBK008_12135
METTCIT01_01615
METOCIT02_00770
MFVMfer_0039 Mfer_0902
AFUAF_0344
AFGAFULGI_00003430 AFULGI_00009190
APOArcpr_0633
ASTAsulf_01218
FPLFerp_1970 Ferp_1979
GACGACE_1486
GAHGAH_01684
PFUPF1281
PFIPFC_05620
PHOPH1083(PH1083)
PABPAB0599
PYNPNA2_1606
PYAPYCH_09780
PYSPy04_1401
PYCTQ32_09335
TKOTK0525
TONTON_0868
TGATGAM_1216(sorA)
TSITSIB_1894
TBATERMP_00355
THEGQS_00690
THATAM4_1892
THMCL1_1840
TLTOCC_12431
THSTES1_0427
TNUBD01_0679
TEUTEU_08965
TGYX802_09850
THVADU37_CDS20220
TCHCHITON_1736
TPEPA0127_01700
TPIEA7C91_10525
TGGA3K92_03870
TCEA3L02_02835
TBSA3L01_04985
THHCDI07_04950
TSLA3L11_09205
TTDA3L14_07310
TPRFA3L09_06990
TRLA3L10_01635
TPAFA3L08_08250
TICFH039_06760
TCQTIRI35C_1297(sorA)
THEMFPV09_02685
PPACPAP_03335
MACMA_3737
MMAMM_0632
MMAZMmTuc01_0646
MMJMSMAS_0677
MMACMSMAC_0678
MLSMSLAZ_2230
METMMSMTP_0741
MEFMSWH1_0882
MEQMSWHS_0941
MSJMSSAC_3547
MSZMSSIH_3089
MSWMSSIT_3146
MHORMSHOH_0795
MBUMbur_0835 Mbur_1006
MMETMCMEM_0965 MCMEM_1494 MCMEM_1628
MELOJ7W08_02865 J7W08_06270 J7W08_07000
MMHMmah_0553 Mmah_0585 Mmah_1131
MHAZBHR79_00485 BHR79_00645 BHR79_07885
MEVMetev_0306 Metev_1346
MZHMzhil_0718
MPYMpsy_1707 Mpsy_2711
MZIHWN40_09155
MHZMetho_0008 Metho_1865
MHUMhun_0773
MRTJKHC33_14045
MLAMlab_0173
MPIMpet_2109
MBNMboo_2085
MFOMetfor_0768
MPLMpal_0613
MPDMCP_0733(sor)
MEZMtc_1945(sor) Mtc_2431(dfx)
RCIRCIX1592(dfx) RCIX2624(sor)
MELUMTLP_09130
MEAMMU439_05560
TARTALC_00613
MAXMMALV_05830
MERMMINT_05210
MEARMpt1_c02720(sorA)
MARCAR505_0630
ABIAboo_0880
ACFAciM339_0127
SMRSmar_0046
SHCShell_0770
IHOIgni_1348
IISEYM_06985
DKADKAM_0429
DFDDesfe_0330
DMUDesmu_0828
TAGTagg_0590
THGTCELL_0978
HBUHbut_1161
PFMPyrfu_0315
PDLPyrde_0034
TPETpen_1830
THBN186_00760
TCBTCARB_1240
THFMA03_01475
THELIG193_07640
FFOFFONT_0713
KCRKcr_0557 Kcr_1172
NEQNEQ011
LOKILokiarch_17190(dfx)
PSYTDSAG12_01108(sorA)
 » show all
Reference
1  [PMID:10514376]
  Authors
Jenney FE Jr, Verhagen MF, Cui X, Adams MW
  Title
Anaerobic microbes: oxygen detoxification without superoxide dismutase.
  Journal
Science 286:306-9 (1999)
DOI:10.1126/science.286.5438.306
  Sequence
[pfu:PF1281]
Reference
2  [PMID:10704199]
  Authors
Yeh AP, Hu Y, Jenney FE Jr, Adams MW, Rees DC.
  Title
Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states.
  Journal
Biochemistry 39:2499-508 (2000)
DOI:10.1021/bi992428k
  Sequence
[pfu:PF1281]
Reference
3  [PMID:10617593]
  Authors
Lombard M, Fontecave M, Touati D, Niviere V
  Title
Reaction of the desulfoferrodoxin from Desulfoarculus baarsii with superoxide anion. Evidence for a superoxide reductase activity.
  Journal
J Biol Chem 275:115-21 (2000)
DOI:10.1074/jbc.275.1.115
  Sequence
[dbr:Deba_2050]
Reference
4  [PMID:11069658]
  Authors
Abreu IA, Saraiva LM, Carita J, Huber H, Stetter KO, Cabelli D, Teixeira M.
  Title
Oxygen detoxification in the strict anaerobic archaeon Archaeoglobus fulgidus: superoxide scavenging by neelaredoxin.
  Journal
Mol Microbiol 38:322-34 (2000)
DOI:10.1046/j.1365-2958.2000.02121.x
Other DBs
ExplorEnz - The Enzyme Database: 1.15.1.2
IUBMB Enzyme Nomenclature: 1.15.1.2
ExPASy - ENZYME nomenclature database: 1.15.1.2
BRENDA, the Enzyme Database: 1.15.1.2
CAS: 250679-67-5

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