KEGG   ENZYME: 1.16.1.7
Entry
EC 1.16.1.7                 Enzyme                                 
Name
ferric-chelate reductase (NADH);
ferric chelate reductase (ambiguous);
iron chelate reductase (ambiguous);
NADH:Fe3+-EDTA reductase;
NADH2:Fe3+ oxidoreductase;
ferB (gene name);
Fe(II):NAD+ oxidoreductase
Class
Oxidoreductases;
Oxidizing metal ions;
With NAD+ or NADP+ as acceptor
Sysname
Fe(II)-siderophore:NAD+ oxidoreductase
Reaction(IUBMB)
2 Fe(II)-siderophore + NAD+ + H+ = 2 Fe(III)-siderophore + NADH [RN:R00092]
Reaction(KEGG)
R00092
Substrate
Fe(II)-siderophore;
NAD+ [CPD:C00003];
H+ [CPD:C00080]
Product
Fe(III)-siderophore;
NADH [CPD:C00004]
Comment
Contains FAD. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The plant enzyme is involved in the transport of iron across plant plasma membranes. The enzyme from the bacterium Paracoccus denitrificans can also reduce chromate. cf. EC 1.16.1.9, ferric-chelate reductase (NADPH) and EC 1.16.1.10, ferric-chelate reductase [NAD(P)H].
History
EC 1.16.1.7 created 1992 as EC 1.6.99.13, transferred 2002 to EC 1.16.1.7, modified 2011, modified 2014
Orthology
K00521  ferric-chelate reductase
Genes
AJM119055631
ATHAT1G01580(FRO2) AT1G01590(FRO1) AT1G23020(FRO3) AT5G23980(FRO4) AT5G23990(FRO5) AT5G49730(FRO6) AT5G49740(FRO7) AT5G50160(FRO8)
ALY9300115 9301828 9301829 9308155 9310224 9311105 9326612 9328114 9328115
CRB17875486 17876579 17881311 17883727 17900195 17900764
CSAT104706695 104709065 104711774 104724271 104724294 104725473 104725475 104725524 104736410 104737747 104738638 104741016 104743100 104752049 104754307 104754309 104756660 104758853 104760957 104760958 104761003 104770770 104776424 104778516
EUSEUTSA_v10003544mg EUTSA_v10006930mg EUTSA_v10006972mg EUTSA_v10012790mg EUTSA_v10012839mg EUTSA_v10028469mg
BRP103836963 103840187 103843795 103843797 103843890 103844661 103854878 103874261
BNA106352010 106370060 106377370 106377373 106380097 106395200 106425673 106430647 106433706 106434146 106434184 106434186 106434937 106435186 106437481 106452002
BOE106293244 106307452 106311524 106314038 106318432 106326287 106343163
RSZ108823660 108823952 108825073 108829530 108829535 108831627 108836493 108857412 108859245 108860288
THJ104800318 104809245 104818163 104825852
CPAP110810118 110810296 110810297 110820914 110820952
CIT102609442 102615568 102620077 102622812 102627420
CICCICLE_v10000235mg CICLE_v10006989mg CICLE_v10019053mg CICLE_v10019061mg
PVY116111940 116111966 116119614 116121373 116121381 116133517 116133535 116134276
MINC123210699 123214863 123223339 123225644
TCC18586305 18603979 18605617 18605618 18614101
GRA105770323 105776367 105798560 105798564 105802725
GHI107923096 107930740 107934204 107951153 107951281 107952230 107952477 107957630 121223702
GAB108450407 108465693 108469354 108482027 108488086
DZI111280962 111290129 111305943 111310268 111313883
EGR104415402 104418726 104418727 104418729 104418730 104418731 104426230 104434108 104443418 104443420
GMX100779692 100790114 100794343 100796460 100804994 100814642 100816560 112998154
GSJ114367115 114371978 114371979 114388290 114390440 114394224 114395865 114418409
PVUPHAVU_003G204400g PHAVU_006G133600g PHAVU_007G073800g PHAVU_007G073900g PHAVU_008G060100g PHAVU_010G101500g
VRA106753318 106759103 106769936 106773621 106773668 106775835
VAR108321581 108324902 108327207 108343239 108346780
VUN114166109 114176823 114186059 114188066 114190422 114190579
CCAJ109792236 109796177 109800553 109802170 109802667 109803882 109803994
APRC113847067 113850265 113853322 113863360 113871806
MTRMTR_1g100130 MTR_1g100150 MTR_2g028530 MTR_4g105080 MTR_8g028780 MTR_8g028795 MTR_8g031070
CAM101499003 101499324 101505212 101511261 101513785
LJALj0g3v0268429.1(Lj0g3v0268429.1) Lj4g3v0072190.1(Lj4g3v0072190.1) Lj4g3v1440660.1(Lj4g3v1440660.1) Lj5g3v1988770.2(Lj5g3v1988770.2) Lj6g3v1693230.1(Lj6g3v1693230.1)
ADU107457844 107472727 107483074
AIP107609299 107628103 107635065 107638776
AHF112702502 112726301 112732410 112741396 112744178 112765774 112796104 112797510
LANG109325658 109325664 109334522 109339259 109339264 109356105 109356247 109362491 109362503
FVE101292220 101292511 101307550 101309010 101311281 105353181
RCN112175623 112176184 112179179 112179180 112181549 112181563 112181569 112181578 112182072 112182073 112182596
PPER18777125 18786837 18787030 18787637 18788529
PMUM103318927 103332089 103333734 103333791 103338170
PAVI110745877 110748786 110751835 110765619 110767769
PDUL117616267 117618446 117619408 117619666 117626889
MDM103428975 103436685 103439801 103439802 103445220 103456307 114822770 114826563
PXB103946433 103953046 103957436 103957437 103958225 103958226 103964313 103964314 103966127 103966184 103967917
ZJU107406527 107414733 107414747 107418289 107423930 107425647 107432941
MNT112093424 21387139 21397392 21397674 21404325
CSV101203723 101204544 101211162 101213325
CMO103484121 103488760 103493281 103498863
BHJ120068478 120070325 120081664 120091586
MCHA111007198 111008081 111010173 111011458
CMAX111477191 111483082 111483092 111484843 111493542
CMOS111430747 111430749 111447866 111458241 111464979
CPEP111780704 111802683 111806537 111810074 111810075
RCU107260839 8261915 8261916 8262647 8277108 8278296 8286523
JCU105628625 105639422 105640315 105641611 105642948 105642950 105648431 105648837 105650949
HBR110635932 110638052 110642080 110643479 110649451 110658174 110660916 110672321
MESC110599944 110614302 110615277 110616522 110616868 110618000
POP18106515 18106516 18110504 7453800 7458053 7487425 7487426 7491487 7496989
PEU105127213 105134209 105135266 105135267 105139193 105139194 105140883 105142058
PALZ118030332 118036765 118037153 118037154 118041611 118044809 118057439
JRE108985875 108992652 108996964 109000920 109001751 109010007
QSU111984982 111985272 112000009 112000010 112001198 112004053 112008918 112011605 112011877 112011887 112011893 112012273 112013840 112027612 112028646 112038464
QLO115959900 115960385 115961249 115962460 115963958 115977685 115977686 115977687 115977688 115987400
TWL119981983 119982031 119983193 120004455
VVI100241516 100246548 100247332 100252447 100256818 100263818
VRI117926945 117932593 117934006 117934403
SLY101246763 101251223 101266014 101268463 543871(FRO1)
SPEN107002501 107008236 107012854 107014546 107019479 107028389
SOT102578364 102578945 102579252 102579721 102587336 102589797 102594930 102606355
CANN107839216 107839217 107839219 107839780 107862583 107863218 107866144 107873964
NTA107760413 107760948 107771783 107776596 107792900 107795235 107795345 107801915 107801919 107804326 107807141 107818188 107818189 107832362
NSY104210558 104214974 104231581 104244607 104244834 104244859 104246484 104246485
NTO104086673 104102930 104105485 104106813 104113481
NAU109205126 109206720 109212317 109221287 109223683 109226543
INI109171567 109171642 109173121 109177042 109185535
ITR115996836 116007127 116013194 116029667 116030260
SIND105157466 105160697 105169029 105172854 105172876 105173155 105173156 110011863
OEU111377055 111391833 111404325 111407634 111409728
EGT105960559 105962617 105963835 105963836 105963838 105964044 105965655 105971615 105971931 105975015 105976846
SSPL121750337 121754283 121758632 121760990 121779368 121779822 121781819 121783691 121795230 121798793
HAN110864890 110878123 110905122 110908923 110926644 110937641 110941738
ECAD122578143 122591142 122592162 122592398 122599846 122603902
LSV111888466 111894618 111894637 111904766 111904772 111914006
CCAV112500369 112506679 112508676 112514558 112514884 112526800
DCR108193054 108194057 108194888 108196555 108204858 108205878 108208697 108210092 108211955 108227088
CSIN114268049 114269844 114269847 114270109 114281916 114287471 114298414 114307225 114318559 114319070
BVG104887088 104888387 104894346 104897075
SOE110784129 110789161 110789863 110792557
CQI110688563 110693851 110693853 110693857 110700333 110714553 110727583 110729606 110731568
NNU104591492 104596257 104603300 104606707 104611528
MING122060673 122066248 122067653 122078813
TSS122638247 122644845 122646641 122657865
PSOM113274781 113284398 113289994 113304276 113304314 113326458 113344018 113355553
NCOL116247455 116247808 116248676 116250877 116252931 116253215
OSA4335953 4336754
DOSAOs04t0444800-01(Os04g0444800) Os04t0578600-01(Os04g0578600)
OBR102708713
BDI100826093 100843941
ATS109733798 109759862
TDC119355256 119355990 119364390 119365126
TAES123041749 123045569 123053413 123054105 123185808 123189317
SBI8080358
ZMA100281526
SITA101763321
SVS117864494
PVIR120641121 120681466
PHAI112898958
PDA103697168 103715667 103717377 103717378
EGU105033551 105043304 105051548
MUS103971203 103989285 103993179 103993180 103993181
DCT110093167 110097844 110115582
PEQ110018408 110020812 110037397
AOF109823679 109824604 109839037
ATR18424390 18427837 18442059
SMOSELMODRAFT_10731 SELMODRAFT_10830 SELMODRAFT_110167 SELMODRAFT_145556 SELMODRAFT_159917 SELMODRAFT_416159 SELMODRAFT_416972 SELMODRAFT_420318 SELMODRAFT_425399 SELMODRAFT_440376 SELMODRAFT_445683 SELMODRAFT_51485
PPP112278480 112283332 112286383 112288516 112293012 112294215
MNGMNEG_0679 MNEG_2902
CSLCOCSUDRAFT_64970
CVRCHLNCDRAFT_57416
APROF751_3250 F751_3251 F751_3252
MISMICPUN_53877
MPPMICPUCDRAFT_46220
GSLGasu_46800
PICPICST_59173(FRE4.1)
LELLELG_04309
COTCORT_0E02920
FVRFVEG_13485
FOXFOXG_08924 FOXG_14662
NHENECHADRAFT_82244 NECHADRAFT_82537
CFJCFIO01_04863 CFIO01_04872 CFIO01_06133
PFYPFICI_05751 PFICI_09141
PSCOLY89DRAFT_697981
ACTACLA_044770
ANGANI_1_3210024(An02g13160)
PFJMYCFIDRAFT_203575
CNECNC02670 CND06030 CNG00950
CNBCNBA1950 CNBD0370 CNBG3850
CGICGB_B2410C CGB_G5410C
TMSTREMEDRAFT_58976 TREMEDRAFT_74287
TASAA1Q1_03144 A1Q1_05173 A1Q1_06677
PPLPOSPLDRAFT_104856 POSPLDRAFT_130027 POSPLDRAFT_134646 POSPLDRAFT_134648 POSPLDRAFT_134651 POSPLDRAFT_134771 POSPLDRAFT_134945 POSPLDRAFT_135058 POSPLDRAFT_98469
TVSTRAVEDRAFT_162444 TRAVEDRAFT_43274 TRAVEDRAFT_66226 TRAVEDRAFT_69649
DSQDICSQDRAFT_105742 DICSQDRAFT_136693 DICSQDRAFT_170031 DICSQDRAFT_170034
PCOPHACADRAFT_108963 PHACADRAFT_259189
SHSSTEHIDRAFT_123515 STEHIDRAFT_131599 STEHIDRAFT_55077
HIRHETIRDRAFT_164205 HETIRDRAFT_313750 HETIRDRAFT_36460 HETIRDRAFT_39263 HETIRDRAFT_39375
PSQPUNSTDRAFT_115913 PUNSTDRAFT_116967 PUNSTDRAFT_119206 PUNSTDRAFT_125114
ADLAURDEDRAFT_156793 AURDEDRAFT_158692 AURDEDRAFT_162494 AURDEDRAFT_78658
FMEFOMMEDRAFT_148974 FOMMEDRAFT_161290 FOMMEDRAFT_74257
GTRGLOTRDRAFT_115899 GLOTRDRAFT_132881 GLOTRDRAFT_48566 GLOTRDRAFT_81132
LBCLACBIDRAFT_304909 LACBIDRAFT_315189
MRRMoror_1019 Moror_11709 Moror_12996 Moror_2446 Moror_4459
CCICC1G_06499
SCMSCHCODRAFT_258803 SCHCODRAFT_258804 SCHCODRAFT_71036
ABPAGABI1DRAFT123369(AGABI1DRAFT_123369) AGABI1DRAFT130257(AGABI1DRAFT_130257) AGABI1DRAFT78089(AGABI1DRAFT_78089) AGABI1DRAFT78091(AGABI1DRAFT_78091)
ABVAGABI2DRAFT120020(AGABI2DRAFT_120020) AGABI2DRAFT123337(AGABI2DRAFT_123337) AGABI2DRAFT187504(AGABI2DRAFT_187504)
CPUTCONPUDRAFT_131705 CONPUDRAFT_85160 CONPUDRAFT_85161
SLASERLADRAFT_401128 SERLADRAFT_442714 SERLADRAFT_442838 SERLADRAFT_478753
WSEWALSEDRAFT_44679
WICJ056_003456
UMAUMAG_11604
PFPPFL1_06279
MGLMGL_2422
MRTMRET_3303
PGRPGTG_08247 PGTG_20853
MLRMELLADRAFT_109893 MELLADRAFT_113404 MELLADRAFT_116791 MELLADRAFT_93237
ACANACA1_222680
SMINv1.2.005108.t1(symbB.v1.2.005108.t1)
FCYFRACYDRAFT_232972(FRO1) FRACYDRAFT_235878 FRACYDRAFT_250055 FRACYDRAFT_252645
PIFPITG_01233 PITG_01324 PITG_02771 PITG_03236 PITG_04582
PSOJPHYSODRAFT_264147 PHYSODRAFT_323311 PHYSODRAFT_354556 PHYSODRAFT_474806 PHYSODRAFT_498767 PHYSODRAFT_505264 PHYSODRAFT_506860 PHYSODRAFT_509769 PHYSODRAFT_555131
SPARSPRG_00043 SPRG_00047 SPRG_02087 SPRG_06468 SPRG_06967 SPRG_10563 SPRG_19396 SPRG_19397
EHXEMIHUDRAFT_195350 EMIHUDRAFT_205158 EMIHUDRAFT_215218 EMIHUDRAFT_225553 EMIHUDRAFT_250790
NGRNAEGRDRAFT_46125 NAEGRDRAFT_47775 NAEGRDRAFT_51918 NAEGRDRAFT_75169 NAEGRDRAFT_82019
 » show all
Reference
1
  Authors
Askerlund, P., Larrson, C. and Widell, S.
  Title
Localization of donor and acceptor sites of NADH dehydrogenase activities using inside-out and right-side-out plasma membrane vesicles from plants.
  Journal
FEBS Lett 239:23-28 (1988)
Reference
2
  Authors
Bruggemann, W. and Moog, P.R.
  Title
NADH-dependent Fe3+ EDTA and oxygen reduction by plasma membrane vesicles from barley roots.
  Journal
Physiol Plant 75:245-254 (1989)
Reference
3
  Authors
Bruggemann, W., Moog, P.R., Nakagawa, H., Janiesch, P. and Kuiper, P.J.C.
  Title
Plasma membrane-bound NADH:Fe3+-EDTA reductase and iron deficiency in tomato (Lycopersicon esculentum). Is there a Turbo reductase ?.
  Journal
Physiol Plant 79:339-346 (1990)
Reference
4
  Authors
Buckhout, T.J. and Hrubec, T.C.
  Title
Pyridine nucleotide-dependent ferricyanide reduction associated with isolated plasma membranes of maize (Zea mays L.) roots.
  Journal
Protoplasma 135:144-154 (1986)
Reference
5
  Authors
Sandelius, A.S., Barr, R., Crane, F.L. and Morre, D.J.
  Title
Redox reactions of plasma membranes isolated from soybean hypocotyls by phase partition.
  Journal
Plant Sci 48:1-10 (1986)
Reference
6  [PMID:14728682]
  Authors
Mazoch J, Tesarik R, Sedlacek V, Kucera I, Turanek J
  Title
Isolation and biochemical characterization of two soluble iron(III) reductases from Paracoccus denitrificans.
  Journal
Eur J Biochem 271:553-62 (2004)
DOI:10.1046/j.1432-1033.2003.03957.x
Other DBs
ExplorEnz - The Enzyme Database: 1.16.1.7
IUBMB Enzyme Nomenclature: 1.16.1.7
ExPASy - ENZYME nomenclature database: 1.16.1.7
BRENDA, the Enzyme Database: 1.16.1.7
CAS: 120720-17-4

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