KEGG   ENZYME: 1.17.1.10Help
Entry
EC 1.17.1.10                Enzyme                                 

Name
formate dehydrogenase (NADP+);
NADP+-dependent formate dehydrogenase
Class
Oxidoreductases;
Acting on CH or CH2 groups;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
formate:NADP+ oxidoreductase
Reaction(IUBMB)
formate + NADP+ = CO2 + NADPH [RN:R00134]
Reaction(KEGG)
Substrate
formate [CPD:C00058];
NADP+ [CPD:C00006]
Product
CO2 [CPD:C00011];
NADPH [CPD:C00005]
Comment
A tungsten-selenium-iron protein characterized from the bacterium Moorella thermoacetica. It is extremely sensitive to oxygen.
History
EC 1.17.1.10 created 1978 as EC 1.2.1.43, transferred 2017 to EC 1.17.1.10
Pathway
ec00680  Methane metabolism
ec00720  Carbon fixation pathways in prokaryotes
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05299  formate dehydrogenase (NADP+) alpha subunit
K15022  formate dehydrogenase (NADP+) beta subunit
Genes
LHK: LHK_02330
SUTT: SUTMEG_16550
BBAY: A4V04_04855
HBL: XJ32_06675
WSU: WS0477(FDHB)
TDN: Suden_1824
SUA: Saut_1830
SKU: Sulku_0269
SULR: B649_01165
HYO: NNO_1954
NIS: NIS_0293
SUN: SUN_2227
GSU: GSU0509(sfrA) GSU0510(sfrB)
GSK: KN400_0498(sfrA) KN400_0499(sfrB)
GME: Gmet_3022(sfrA) Gmet_3023(sfrB)
GBM: Gbem_0659(sfrB) Gbem_0660(sfrA)
GEO: Geob_1607(sfrB) Geob_1608(sfrA)
PCA: Pcar_2503(sfrB)
DVU: DVU1772
DVL: Dvul_1383
DDS: Ddes_1543
PPRF: DPRO_0998
DBA: Dbac_0167
DPS: DP0682
DAT: HRM2_16890(fdhA6) HRM2_26590(gltD1)
DTO: TOL2_C28850(fdhA2)
RPA: RPA0135
RPE: RPE_3861
RPT: Rpal_0138
BVR: BVIR_2956
BLAG: BLTE_01210
RHC: RGUI_3847
DSY: DSY3968(fdhF)
DHD: Dhaf_1398
DAU: Daud_0104
SGY: Sgly_2685
HMO: HM1_1745(fdhA)
CHY: CHY_0733(fdhA)
MTA: Moth_2314
TOC: Toce_0785
CAD: Curi_c16640(fdhB)
MTH: MTH_1552
MMG: MTBMA_c01380(fdhA1)
METC: MTCT_1417
MTP: Mthe_0915
 » show all
Taxonomy
Reference
1  [PMID:4154039]
  Authors
Andreesen JR, Ljungdahl LG.
  Title
Nicotinamide adenine dinucleotide phosphate-dependent formate dehydrogenase from Clostridium thermoaceticum: purification and properties.
  Journal
J Bacteriol 120:6-14 (1974)
Reference
2  [PMID:6822536]
  Authors
Yamamoto I, Saiki T, Liu SM, Ljungdahl LG.
  Title
Purification and properties of NADP-dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten-selenium-iron protein.
  Journal
J Biol Chem 258:1826-32 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 1.17.1.10
IUBMB Enzyme Nomenclature: 1.17.1.10
ExPASy - ENZYME nomenclature database: 1.17.1.10
BRENDA, the Enzyme Database: 1.17.1.10
CAS: 51377-43-6

DBGET integrated database retrieval system