KEGG ENZYME: 1.17.2.1

ENZYME: 1.17.2.1

Entry

EC 1.17.2.1                 Enzyme

Name

nicotinate dehydrogenase (cytochrome);
nicotinic acid hydroxylase;
nicotinate hydroxylase

Class

Oxidoreductases;
Acting on CH or CH2 groups;
With a cytochrome as acceptor

Sysname

nicotinate:cytochrome 6-oxidoreductase (hydroxylating)

Reaction(IUBMB)

nicotinate + a ferricytochrome + H2O = 6-hydroxynicotinate + a ferrocytochrome + 2 H+ [RN:R09473]

Reaction(KEGG)

R09473

Substrate

nicotinate [CPD:C00253];
ferricytochrome [CPD:C00923];
H2O [CPD:C00001]

Product

6-hydroxynicotinate [CPD:C01020];
ferrocytochrome [CPD:C00924];
H+ [CPD:C00080]

Comment

This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases, but differs from most other members of this family. While most members contain an FAD cofactor, the large subunit of this enzyme contains three c-type cytochromes, enabling it to interact with the electron transfer chain, probably by delivering the electrons to a cytochrome oxidase. The small subunit contains a typical molybdopterin cytosine dinucleotide(MCD) cofactor and two [2Fe-2S] clusters [1].

History

EC 1.17.2.1 created 2010

Pathway

ec00760

Nicotinate and nicotinamide metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K18029

nicotinate dehydrogenase subunit A

K18030

nicotinate dehydrogenase subunit B

Genes

IZH:	FEM41_12580 FEM41_12585

SMAR:

SM39_1773 SM39_1774 SM39_1932 SM39_1933

SMAC:

SMDB11_1586 SMDB11_1587 SMDB11_1756 SMDB11_1757

SMW:	SMWW4_v1c23280 SMWW4_v1c23290 SMWW4_v1c24880 SMWW4_v1c24890

SPE:	Spro_2314 Spro_2315 Spro_2491 Spro_2492

SRR:	SerAS9_2271 SerAS9_2272

SRL:	SOD_c21440(nicA) SOD_c21450(nicB1)

SRY:	M621_11745 M621_11750

SPLY:

Q5A_011880(nicA) Q5A_011885(nicB)

SRS:	SerAS12_2271 SerAS12_2272

SRA:	SerAS13_2272 SerAS13_2273

SMAF:

D781_1722 D781_1723

SLQ:	M495_11515 M495_11520 M495_12380 M495_12385

SERF:

L085_16260 L085_16265 L085_17100 L085_17105

SERS:

SERRSCBI_11735 SERRSCBI_11740

SFW:	WN53_13060 WN53_13065

SFG:	AV650_08560 AV650_08565

SRZ:	AXX16_3400 AXX16_3401

SERM:

CLM71_08335 CLM71_08340

SQU:	E4343_03765 E4343_03770 E4343_04615 E4343_04620

SFJ:	SAMEA4384070_2383(iorA_1) SAMEA4384070_2384(adhB_1)

SOF:	NCTC11214_04485(adhB_2) NCTC11214_04486(iorA_2)

SSUR:

ATE40_009125 ATE40_009130

SURI:

J0X03_11475 J0X03_11480 J0X03_12350 J0X03_12355

SRHZ:

FO014_01605 FO014_01610

GQU:	AWC35_02960 AWC35_02965

EAME:

GXP68_16300

EPE:	CI789_03025 CI789_03030

PAO:	Pat9b_5172 Pat9b_5173

TCI:	A7K98_12050 A7K98_12055

TPTY:

NCTC11468_02204(iorA) NCTC11468_02205

PHEI:

NCTC12003_00963(iorA) NCTC12003_00964

PFQ:	QQ39_14990 QQ39_14995

PAE:	PA1601 PA1602

PAEV:

N297_1646 N297_1647

PAEI:

N296_1646 N296_1647

PAU:	PA14_43780 PA14_43790

PAP:	PSPA7_3672 PSPA7_3673

PAG:	PLES_37251 PLES_37261

PAF:	PAM18_3445 PAM18_3446

PNC:	NCGM2_2492 NCGM2_2493

PAEB:

NCGM1900_4972 NCGM1900_4973

PDK:	PADK2_17700 PADK2_17705

PSG:	G655_17200 G655_17205

PRP:	M062_08535 M062_08540

PAEP:

PA1S_18005 PA1S_18010

PAER:

PA1R_gp5182 PA1R_gp5183

PAEM:

U769_17735 U769_17740

PAEL:

T223_19065 T223_19070

PAES:

SCV20265_3810 SCV20265_3811

PAEU:

BN889_01714 BN889_01715

PAEG:

AI22_15970 AI22_15975

PAEC:

M802_1643 M802_1644

PAEO:

M801_1645 M801_1646

PMUI:

G4G71_18220 G4G71_18225

PPU:	PP_3947(nicA) PP_3948(nicB)

PPF:	Pput_1889 Pput_1890

PPG:	PputGB1_3582 PputGB1_3583

PPW:	PputW619_2135 PputW619_2136

PPB:	PPUBIRD1_1860(ndhL) PPUBIRD1_1861

PPI:	YSA_08959 YSA_08961

PPX:	T1E_2079 T1E_2080

PPUT:

L483_21725 L483_21730

PPUN:

PP4_17740 PP4_17750

POR:	APT59_07070 APT59_07075

PFO:	Pfl01_2446 Pfl01_2447(iorA)

PFS:	PFLU_2802 PFLU_2803

PFB:	VO64_0129 VO64_0130

PVR:	PverR02_20840 PverR02_20845

PAZO:

AYR47_21630 AYR47_21635

PFW:	PF1751_v1c24730 PF1751_v1c24740

PFF:	PFLUOLIPICF724360 PFLUOLIPICF724365

PFX:	A7318_11810 A7318_11815

PLUL:

FOB45_13260 FOB45_13265

PSV:	PVLB_10355 PVLB_10360

PSK:	U771_14870 U771_14875 U771_21620 U771_21625

PCH:	EY04_18455 EY04_18460 EY04_20270 EY04_20275

PCZ:	PCL1606_21910 PCL1606_21920

PCP:	JM49_10935 JM49_10940

PFZ:	AV641_08740 AV641_08745

PSEM:

TO66_20980 TO66_20985

PKR:	AYO71_17055 AYO71_17060

PANR:

A7J50_2719 A7J50_2720

PPSL:

BJP27_21875 BJP27_21880

PSIL:

PMA3_12580 PMA3_12585

PYM:	AK972_2678 AK972_2679

PGG:	FX982_03131 FX982_03132 FX982_04196 FX982_04197

PGY:	AWU82_14920 AWU82_14925

PVK:	EPZ47_17400 EPZ47_17405

PEZ:	HWQ56_12845 HWQ56_12850

PATA:

JWU58_13220 JWU58_13225

PZE:	HU754_014615 HU754_014620

PMOE:

HV782_015340 HV782_015345

PTZ:	HU718_015440 HU718_015445

PHV:	HU739_004280 HU739_004285

PANH:

HU763_008050 HU763_008055

PIE:	HU724_015275 HU724_015280

PWY:	HU734_022670 HU734_022675

PTAE:

NCTC10697_01686(iorA) NCTC10697_01687(adhB_1)

AMAA:

amad1_11665

AMAL:

I607_10990

AMAE:

I876_11360

AMAO:

I634_11215

AMAD:

I636_11245

AMAI:

I635_11650

AMAG:

I533_10995

HAM:	HALO0538 HALO0544 HALO0545

HVN:	EI420_01955 EI420_01985 EI420_01990

HOL:	HORIV_65010 HORIV_65020 HORIV_65180

HAXI:

HAALTHF_14270n

HTT:	HZS52_07530 HZS52_07560 HZS52_07565

HSV:	HNO53_05745 HNO53_05750 HNO53_05780

HTX:	EKK97_06030 EKK97_06035

ADI:	B5T_02298(coxL) B5T_02299 B5T_02300

MARS:

A8C75_16285 A8C75_16290 A8C75_16330

RPJ:	N234_04305 N234_04310 N234_04345

RIN:	ACS15_2998(nicA) ACS15_2999

REH:	H16_A0920(h16_A0920) H16_A0921(h16_A0921) H16_A0928(h16_A0928)

CNC:	CNE_1c08700(adhB1) CNE_1c08710(iorA1) CNE_1c08780(iorB1)

CUH:	BJN34_04885 BJN34_04890 BJN34_04925 BJN34_29055 BJN34_29060

REU:	Reut_A2516 Reut_A2517

CTI:	RALTA_A0865 RALTA_A0866 RALTA_A0873

CBW:	RR42_s0166 RR42_s0167 RR42_s0174

CGD:	CR3_3004(coxL) CR3_3011(nicA)

CCUP:

BKK81_07345 BKK81_07350 BKK81_07380 BKK81_24770 BKK81_24775

CUP:	BKK80_06645 BKK80_06650 BKK80_06680 BKK80_31590 BKK80_31595

CUU:	BKK79_05470 BKK79_05500 BKK79_05505 BKK79_22475 BKK79_22480

CPAU:

EHF44_26990 EHF44_26995 EHF44_27030

COX:	E0W60_14745 E0W60_14750 E0W60_14785

BOK:	DM82_4531 DM82_4532

BOC:	BG90_6061 BG90_6062

BUU:	WS70_19565 WS70_19570

BSAV:

WS86_30255 WS86_30260 WS86_30290

BVI:	Bcep1808_6385 Bcep1808_6386

BVE:	AK36_5818 AK36_5819

BCN:	Bcen_1471 Bcen_1472 Bcen_4322 Bcen_4323 Bcen_4329

BCH:	Bcen2424_4037 Bcen2424_4043 Bcen2424_4044 Bcen2424_6356 Bcen2424_6357

BCM:	Bcenmc03_3481 Bcenmc03_3482 Bcenmc03_3488 Bcenmc03_7022 Bcenmc03_7023

BCJ:	BCAM1140 BCAM1147 BCAM1148

BCEN:

DM39_3874 DM39_3875 DM39_3881

BCEW:

DM40_5850 DM40_5851

BCEO:

I35_4987 I35_4993 I35_4994 I35_7713 I35_7714

BAM:	Bamb_5819 Bamb_5820

BAC:	BamMC406_5602 BamMC406_5603

BMJ:	BMULJ_03958(coxL)

BMU:	Bmul_4545 Bmul_4546 Bmul_4552

BMK:	DM80_3715 DM80_3716 DM80_3722

BMUL:

NP80_4067 NP80_4073 NP80_4074

BCED:

DM42_3943 DM42_3944 DM42_3950 DM42_7239 DM42_7240

BCEP:

APZ15_36000 APZ15_36005

BDL:	AK34_5643 AK34_5644

BPYR:

ABD05_32290 ABD05_32295

BCON:

NL30_06895 NL30_06900 NL30_06930 NL30_31255 NL30_31260

BUB:	BW23_3 BW23_4 BW23_4786

BDF:	WI26_30555 WI26_30560

BLAT:

WK25_19435 WK25_19440

BTEI:

WS51_30325 WS51_30330

BSEM:

WJ12_20590 WJ12_20595 WJ12_25600 WJ12_25630 WJ12_25635

BPSL:

WS57_08390 WS57_08395 WS57_08425 WS57_18195 WS57_18200

BMEC:

WJ16_24230 WJ16_24260 WJ16_24265

BSTG:

WT74_19670 WT74_19675 WT74_20815 WT74_20845 WT74_20850

BANN:

JFN94_22945 JFN94_22975 JFN94_22980

BUG:	BC1001_4280 BC1001_4281 BC1001_5752 BC1001_5753

BGF:	BC1003_3912 BC1003_3913 BC1003_5119 BC1003_5120 BC1003_5623 BC1003_5624

BGD:	bgla_1g12650 bgla_1g12710 bgla_1g12720

BGO:	BM43_2597 BM43_2603 BM43_2604

BUK:	MYA_5779 MYA_5780

BUQ:	AC233_28065 AC233_28070

BGP:	BGL_1c11580 BGL_1c11640 BGL_1c11650 BGL_1c21360(iorB)

BPLA:

bpln_1g11100 bpln_1g11160 bpln_1g11170 bpln_1g19790 bpln_1g19800

BUM:	AXG89_36950 AXG89_36985 AXG89_36990 AXG89_39840 AXG89_39845

BUI:	AX768_15600 AX768_15605 AX768_15640 AX768_20065

BURK:

DM992_20080 DM992_20085 DM992_20115 DM992_38545 DM992_38550

BXE:	Bxe_B0662 Bxe_B0663

BXB:	DR64_5993 DR64_5994

BPH:	Bphy_5703 Bphy_5704

BGE:	BC1002_5510 BC1002_5511

BPX:	BUPH_00864 BUPH_00865 BUPH_06042 BUPH_06043

BPY:	Bphyt_4331 Bphyt_4332 Bphyt_5505 Bphyt_5506

BUZ:	AYM40_28660 AYM40_28665 AYM40_29655 AYM40_29660 AYM40_31810 AYM40_31815

BFN:	OI25_6349 OI25_6350 OI25_6797 OI25_6803 OI25_6804

BCAI:

K788_0005021 K788_0005022 K788_0007376 K788_0007377 K788_0007383

PSPW:

BJG93_19840 BJG93_19845 BJG93_23420 BJG93_23425 BJG93_25165 BJG93_25170

PARA:

BTO02_16645 BTO02_16650 BTO02_29305

PARB:

CJU94_26115 CJU94_26120 CJU94_31350 CJU94_31355

PHS:	C2L64_08185 C2L64_08190 C2L64_45575 C2L64_45580

PTER:

C2L65_30575 C2L65_30605 C2L65_30610

PGP:	CUJ91_28145 CUJ91_28150 CUJ91_32350 CUJ91_32355

PCJ:	CUJ87_18545 CUJ87_18550 CUJ87_25405 CUJ87_25410

PTS:	CUJ90_21645 CUJ90_21650 CUJ90_26310 CUJ90_26315

PCAF:

DSC91_000568

PMEG:

FNZ07_07700 FNZ07_07705 FNZ07_24545 FNZ07_24550

PTRO:

G5S35_31860 G5S35_31865 G5S35_31895 G5S35_35935 G5S35_35940

PEW:	KZJ38_05555 KZJ38_05560

PDIO:

PDMSB3_0673.1 PDMSB3_0674.1(nicA) PDMSB3_2711.1(nicB) PDMSB3_2712.1(nicA)

PSPU:

NA29_11630 NA29_11660 NA29_11665

PVE:	UC34_12630 UC34_12660 UC34_12665

POX:	MB84_21150

PNR:	AT302_20370 AT302_20375 AT302_20405

CABA:

SBC2_37440(nicB_1) SBC2_37450(nicA_1) SBC2_37530(nicB_2) SBC2_46120(nicB_3) SBC2_46130(nicA_2)

BUO:	BRPE64_DCDS10940 BRPE64_DCDS10950 BRPE64_DCDS11020

BPE:

BP1953

BPC:

BPTD_1925

BPER:

BN118_0961

BPEU:

Q425_14990

BPAR:

BN117_1480 BN117_1486

BPA:	BPP2326 BPP2332

BBH:	BN112_1732 BN112_1738 BN112_1739

BBR:	BB1776 BB1777 BB1783

BBM:	BN115_1678 BN115_1679

BBX:	BBS798_1677 BBS798_1678 BBS798_1684

BPT:	Bpet3961 Bpet3962

BAV:	BAV1527 BAV1533(iorA) BAV1534

BBRO:

BAU06_19445 BAU06_19450 BAU06_19680 BAU06_19685

BFZ:	BAU07_06765 BAU07_06770 BAU07_06995 BAU07_07000 BAU07_08020 BAU07_08025 BAU07_16145 BAU07_16155 BAU07_16160

BOH:	AKI39_05180 AKI39_05185 AKI39_18745 AKI39_18965 AKI39_18970

BGM:	CAL15_06245 CAL15_06250 CAL15_06255 CAL15_11460 CAL15_11490 CAL15_11495

AXO:	NH44784_051861 NH44784_051871 NH44784_051931

AXN:	AX27061_3324 AX27061_3329

AXX:	ERS451415_03303(adhB_1) ERS451415_03304(iorA_1) ERS451415_03309

ADT:	APT56_16380 APT56_16385 APT56_16410

AIS:	BUW96_28740 BUW96_28765 BUW96_28770

ASW:	CVS48_09635 CVS48_09665 CVS48_09670

ACHB:

DVB37_25120

PUD:	G9Q38_13510 G9Q38_13520 G9Q38_13525

AKA:	TKWG_19815 TKWG_19820

AMIM:

MIM_c31100 MIM_c31110 MIM_c31120

AFA:	UZ73_14745 UZ73_14750 UZ73_14755

AFQ:	AFA_14975(nicB2) AFA_14980(nicA) AFA_14985(nicB2)

AAQU:

D3M96_15905 D3M96_15910 D3M96_15915

AAMM:

FE795_13835 FE795_13840 FE795_13845

PHN:	PAEH1_09760 PAEH1_09765 PAEH1_09770

ODI:	ODI_R3893 ODI_R3894 ODI_R3900

PIG:	EGT29_00400

PACR:

FXN63_06600 FXN63_06605 FXN63_06620

PARK:

LSG25_03735 LSG25_13425 LSG25_13430

RFR:

Rfer_0864

RHY:	RD110_24175

POL:	Bpro_4058 Bpro_4059

AAV:	Aave_3925 Aave_3926

AAA:	Acav_3822 Acav_3823 Acav_3829

ACK:	C380_01190 C380_01195

AANT:

HUK68_19200 HUK68_19205

ARAD:

KI609_01190 KI609_01195

DAC:	Daci_1848 Daci_1854 Daci_1855 Daci_3930 Daci_3931

DEL:	DelCs14_2885 DelCs14_2886 DelCs14_4783 DelCs14_4784 DelCs14_4790

DTS:	BI380_05630 BI380_05635 BI380_15375 BI380_15380 BI380_15410

DHK:	BO996_08750 BO996_08780 BO996_08785 BO996_17920 BO996_17925

DLA:	I6G47_04510 I6G47_04515 I6G47_15005 I6G47_15010 I6G47_15040

VAP:	Vapar_0189 Vapar_0190

VPE:	Varpa_0217 Varpa_0218

VPD:	VAPA_1c02240 VAPA_1c02250

VAA:	AX767_09735 AX767_09740

VBO:	CKY39_01185 CKY39_01190

VAM:	C4F17_17880 C4F17_17885 C4F17_28475 C4F17_28480

CTT:	CtCNB1_3770 CtCNB1_3771

CTES:

O987_22820 O987_22825 O987_23165 O987_23170

LIM:	L103DPR2_00172(nicB_1) L103DPR2_00173(nicA_1) L103DPR2_00692(nicA_2)

HYN:	F9K07_08765 F9K07_08770 F9K07_08775

DIH:	G7047_00285 G7047_00290

DAER:

H9K75_17545

DRG:	H9K76_16560 H9K76_16565

HSE:	Hsero_1321 Hsero_1322(iorA) Hsero_1327(coxL)

HSZ:	ACP92_06610 ACP92_06615 ACP92_06640

HHT:	F506_09950 F506_09955

HEE:	hmeg3_15610 hmeg3_15615 hmeg3_19240 hmeg3_19245 hmeg3_19275

HFR:	G5S34_06820 G5S34_06825 G5S34_06850

MTIM:

DIR46_18535 DIR46_18540 DIR46_21135 DIR46_21140 DIR46_21165

MFLA:

GO485_02600 GO485_02605

DUG:	HH213_22810 HH213_22815

XYK:	GT347_16820 GT347_16825

AZR:	CJ010_22070 CJ010_22100 CJ010_22105

BEBA:

BWI17_05510 BWI17_05515

DAL:

Dalk_2371

MYM:	A176_000839 A176_000840

CCX:	COCOR_06361(iorA2) COCOR_06362(iorB2)

MFU:	LILAB_16010 LILAB_16015

MMAS:

MYMAC_005836 MYMAC_005837

SUR:	STAUR_8008 STAUR_8009

MBD:	MEBOL_007950 MEBOL_007951

CFUS:

CYFUS_005901 CYFUS_005902

CCRO:

CMC5_078300(aldA) CMC5_078310

MLN:	A9174_33995 A9174_34000

MOP:	Mesop_2583 Mesop_2584

MESR:

FGU64_15270 FGU64_15275

MES:	Meso_1906 Meso_1907

HOE:	IMCC20628_00188

SME:	SM_b20403 SM_b20404

SMK:	Sinme_3774 Sinme_3775

SMQ:	SinmeB_4270 SinmeB_4271

SMX:	SM11_pD1209 SM11_pD1210

SMI:	BN406_06268 BN406_06269

SMEG:

C770_GR4pD1198 C770_GR4pD1199

SMEL:

SM2011_b20403 SM2011_b20404

SMER:

DU99_31280 DU99_31285

SFD:	USDA257_c51590(iorA2) USDA257_c51600

EAD:	OV14_b1099 OV14_b1100

ESJ:	SJ05684_b50550 SJ05684_b50560

EAK:	EKH55_5063 EKH55_5064

EMX:	FKV68_33200 FKV68_33205

ARA:	Arad_8291 Arad_8292(xdhA)

RLG:	Rleg_6039 Rleg_6040

RTR:	RTCIAT899_PC08605 RTCIAT899_PC08610

RGA:	RGR602_PC02379 RGR602_PC02380

RJG:	CCGE525_26725 CCGE525_26730 CCGE525_29810 CCGE525_29815

RAD:	CO657_35850 CO657_35855

RII:	FFM53_028485 FFM53_028490

RRG:	J3P73_36825 J3P73_36830

RLS:	HB780_10930

NGL:	RG1141_PA14100 RG1141_PA14110

NGG:	RG540_CH26730 RG540_CH26740 RG540_PA15830 RG540_PA15840

NEN:	NCHU2750_46220(nicA) NCHU2750_46230(nicB)

SHZ:	shn_22420 shn_22425

BJA:	bll3820(bll3820) bll3821(bll3821) blr6047(blr6047)

BJU:	BJ6T_36570 BJ6T_60360 BJ6T_60370

BJP:	RN69_17730 RN69_29245 RN69_29250

BRA:	BRADO2114 BRADO2115 BRADO3160 BRADO3161

BBT:	BBta_2423 BBta_2424

BRS:	S23_22240 S23_44210 S23_44220

AOL:	S58_54190 S58_54200

BRC:	BCCGELA001_15865 BCCGELA001_15870

BRAD:

BF49_1225 BF49_1226 BF49_5582

BIC:	LMTR13_10455 LMTR13_29575 LMTR13_29580

BRO:	BRAD285_5146 BRAD285_5147

BRK:	CWS35_16935 CWS35_16940

BOT:	CIT37_24020 CIT37_34800 CIT37_34805

BRQ:	CIT40_11900 CIT40_11905 CIT40_22230

BGQ:	X265_12645 X265_24205 X265_24210

BGZ:	XH91_11290 XH91_21390 XH91_21395

BSYM:

CIT39_11140 CIT39_11145 CIT39_21430

BBET:

F8237_03115 F8237_03120 F8237_26200

BARH:

WN72_20520 WN72_20525 WN72_33830

BVZ:	BRAD3257_3073(nicA) BRAD3257_5215(nicA) BRAD3257_5216(nicB)

BEL:	BE61_03760 BE61_03770 BE61_16410 BE61_16420 BE61_72870 BE61_72880

BDG:	LPJ38_21275 LPJ38_21280

BSEP:

HAP48_0029590 HAP48_0029595

BQB:	J4P68_0027990 J4P68_0027995 J4P68_0030860 J4P68_0030865

RPB:	RPB_1668 RPB_1669

RBK:	E0H22_02815 E0H22_02820

NHA:	Nham_1181 Nham_1182

OCA:	OCAR_7507 OCAR_7508

OCG:	OCA5_c06290 OCA5_c06300

OCO:	OCA4_c06280 OCA4_c06290

BOP:	AXW83_08755 AXW83_08760 AXW83_24155 AXW83_24160

BOS:	BSY19_2455

BOI:	BLM15_19745 BLM15_19750

BOF:	FQV39_30330 FQV39_30335

XAU:	Xaut_4209 Xaut_4210

XDI:	EZH22_09205 EZH22_09210 EZH22_20075 EZH22_20080

AZC:	AZC_2800 AZC_2801

STAR:

G3545_15130 G3545_15135

APRA:

G3A50_11860 G3A50_11865

MPO:	Mpop_0236 Mpop_0237

MET:	M446_3137 M446_3138

MNO:	Mnod_8450 Mnod_8451

MAQU:

Maq22A_1p31265(coxL) Maq22A_1p38300(coxS) Maq22A_c03040(coxL) Maq22A_c03045(coxS)

MEE:	DA075_03460 DA075_03465 DA075_32190

METD:

C0214_00675 C0214_00680

METS:

DK389_20535 DK389_20540

MTEA:

DK419_12575 DK419_12580 DK419_23870 DK419_23875

MIND:

mvi_11820 mvi_11830 mvi_18210 mvi_18220

MOC:	BB934_38760 BB934_38765

MSL:	Msil_3374 Msil_3375

HMC:	HYPMC_0197

RHZ:	RHPLAN_07050 RHPLAN_11250 RHPLAN_11260 RHPLAN_20980 RHPLAN_35160 RHPLAN_35170 RHPLAN_51460 RHPLAN_51470

PLEO:

OHA_2_00104(nicB) OHA_2_00105(nicA)

HDI:	HDIA_4147(nicB_2) HDIA_4148(nicA_1) HDIA_4442(nicA_2) HDIA_4443(nicB_3)

MMED:

Mame_02898(nicA) Mame_02899(nicB_3)

AUA:	M673_15770 M673_15775

AUB:	LXB15_07205 LXB15_07210

PSIN:

CAK95_00085 CAK95_00090 CAK95_18005 CAK95_18010

PPHR:

APZ00_25400 APZ00_25405

PSTG:

E8M01_24610 E8M01_24615

LIZ:	LGH83_07400 LGH83_07405

CAUL:

KCG34_06245

JAN:	Jann_0874 Jann_0875

RPON:

G3256_05205 G3256_05210

SMED:

JNX03_08665 JNX03_08670

SAGU:

CDO87_22410 CDO87_22415

PYE:	A6J80_23235 A6J80_23240

PSHQ:

F3W81_00960 F3W81_00965

PALW:

PSAL_015660(nicA) PSAL_015670(nicB_2)

FAP:	GR316_11010 GR316_11015

NAR:

Saro_1347

NPP:	PP1Y_Mpl8777 PP1Y_Mpl8785

NOT:	C7W88_09395 C7W88_15625 C7W88_22085

SECH:

B18_19790 B18_19795

SYA:	A6768_08040

ADO:	A6F68_00953(nicA)

TFV:	IDJ81_01090

GOY:	GLS_c14200 GLS_c14210

GAL:	A0U94_10325 A0U94_10330

GTI:	FXF46_02585 FXF46_02590

GSP:	IGS75_12395 IGS75_12400

ACR:	Acry_3005 Acry_3006

AMV:	ACMV_33490 ACMV_33500

KSC:	CD178_02880(nicB_2) CD178_02881(nicA)

APT:	APA01_23770 APA01_23780

APW:	APA42C_23770 APA42C_23780

APF:	APA03_23770 APA03_23780

APU:	APA07_23770 APA07_23780

APG:	APA12_23770 APA12_23780

APQ:	APA22_23770 APA22_23780

APX:	APA26_23770 APA26_23780

APZ:	APA32_23770 APA32_23780

APK:	APA386B_1211 APA386B_1212(iorA)

ASV:	WG31_11910 WG31_11915

APOM:

CPF11_08765 CPF11_08770

ATO:	CIW82_09415 CIW82_09420

AASC:

A4S02_13820 A4S02_13825

ACET:

DS739_11640 DS739_11645

ROS:	CTJ15_00270 CTJ15_00275

RMUC:

FOB66_01415 FOB66_01420

RMT:	IAI58_12905 IAI58_12910

SHUM:

STHU_16280 STHU_16290

SVC:	STVA_18430 STVA_18440

ALI:	AZOLI_p20430 AZOLI_p20431

ABQ:	ABAZ39_09545

AZT:	TSH58p_07080

AZM:	DM194_20110 DM194_20115

AOZ:	HUE56_03335 HUE56_03340 HUE56_08310 HUE56_08315

SKT:	IGS68_32650 IGS68_32655

SMUC:

JL100_033685 JL100_033690

SROE:

JL101_031140 JL101_031145

MAG:	amb1301 amb1303

MAGX:

XM1_1925 XM1_1926(pucE)

MAGN:

WV31_17385 WV31_17390

PARH:

I5S86_12055 I5S86_12060

MSAK:

MSAS_40520

MKU:	I2456_03490

MLL:	B1R94_09310 B1R94_09315

MMAG:

MMAD_51020 MMAD_51030

MTY:	MTOK_25960 MTOK_25970

SLIA:

HA039_11985 HA039_11990

NCA:	Noca_4457 Noca_4458

NOY:	EXE57_13260 EXE57_13265

NGN:	LCN96_13270

ACE:	Acel_0896 Acel_0897

PLAB:

C6361_08065 C6361_08070

PLAT:

C6W10_04630 C6W10_04635

TTR:

Tter_2353

DCH:	SY84_11195

OTE:	Oter_3127 Oter_3128

OBG:	Verru16b_02805(nicB_3) Verru16b_02806(nicA_2)

LUO:	HHL09_25665

PND:	Pla175_26890(nicB)

AGV:	OJF2_57870(nicB)

TALB:

FTW19_07555 FTW19_17450 FTW19_22305

SUS:	Acid_4799 Acid_4800 Acid_7218 Acid_7219

PFER:

IRI77_33790

ABAC:

LuPra_02179(nicB_1) LuPra_02180(nicA_1) LuPra_05705(nicA_2)

DORI:

FH5T_11980

DRC:	G0Q07_18095

MCOS:

GM418_00345

NKO:	Niako_5870 Niako_5871

PSEG:

D3H65_15515 D3H65_15520

SHG:	Sph21_1188 Sph21_1189

OLI:	FKG96_02875 FKG96_02880 FKG96_18055 FKG96_18060

CMR:	Cycma_0988

CAMU:

CA2015_0886

BBD:	Belba_3799 Belba_3800

MDA:	IPZ59_09740 IPZ59_09745

RHOZ:

GXP67_30565 GXP67_30570

HQI:	H9L05_17285

ADD:	HUW48_22085

ASWU:

HUW51_15275

CHK:	D4L85_25570

ZPR:	ZPR_2974 ZPR_2975

AALG:

AREALGSMS7_00647(nicA) AREALGSMS7_00648

EMAR:

D1013_18475 D1013_18480

AFLA:

FHG64_12520 FHG64_12525

» show all

Reference

1 [PMID:18678916]

Authors

Jimenez JI, Canales A, Jimenez-Barbero J, Ginalski K, Rychlewski L, Garcia JL, Diaz E

Title

Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.

Journal

Proc Natl Acad Sci U S A 105:11329-34 (2008)
DOI:10.1073/pnas.0802273105

Sequence

[ppu:PP_3947 PP_3948]

Reference

2 [PMID:19118407]

Authors

Yang Y, Yuan S, Chen T, Ma P, Shang G, Dai Y

Title

Cloning, heterologous expression, and functional characterization of the nicotinate dehydrogenase gene from Pseudomonas putida KT2440.

Journal

Biodegradation 20:541-9 (2009)
DOI:10.1007/s10532-008-9243-x

Sequence

[ppu:PP_3947 PP_3948]

Other DBs

ExplorEnz - The Enzyme Database:

1.17.2.1

IUBMB Enzyme Nomenclature:

1.17.2.1

ExPASy - ENZYME nomenclature database:

1.17.2.1

BRENDA, the Enzyme Database:

1.17.2.1

DBGET integrated database retrieval system