KEGG ENZYME: 1.18.1.6

ENZYME: 1.18.1.6

Entry

EC 1.18.1.6                 Enzyme

Name

adrenodoxin-NADP+ reductase;
adrenodoxin reductase;
nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase;
AdR;
NADPH:adrenal ferredoxin oxidoreductase;
NADPH-adrenodoxin reductase

Class

Oxidoreductases;
Acting on iron-sulfur proteins as donors;
With NAD+ or NADP+ as acceptor

Sysname

reduced adrenodoxin:NADP+ oxidoreductase

Reaction(IUBMB)

2 reduced adrenodoxin + NADP+ + H+ = 2 oxidized adrenodoxin + NADPH [RN:R10159]

Reaction(KEGG)

R10159

Substrate

reduced adrenodoxin [CPD:C00662];
NADP+ [CPD:C00006];
H+ [CPD:C00080]

Product

oxidized adrenodoxin [CPD:C00667];
NADPH [CPD:C00005]

Comment

A flavoprotein (FAD). The enzyme, which transfers electrons from NADPH to adrenodoxin molecules, is the first component of the mitochondrial cytochrome P-450 electron transfer systems, and is involved in the biosynthesis of all steroid hormones.

History

EC 1.18.1.6 created 1965 as EC 1.6.99.4, transferred 1972 as EC 1.6.7.1, transferred 1978 to EC 1.18.1.2, part transferred 2012 to EC 1.18.1.6, modified 2016

Orthology

K18914

adrenodoxin-NADP+ reductase

Genes

HSA:	2232(FDXR)

PTR:	454869(FDXR)

PPS:	100974527(FDXR)

GGO:	101147693(FDXR)

PON:	100437093(FDXR)

PPYG:

129016697(FDXR)

NLE:	100604648 115830454 115838360

HMH:	116483498(FDXR)

SSYN:

129461789 129463096

MCC:	699336(FDXR)

MCF:	102137303(FDXR)

MTHB:

126939201

MNI:	105469138(FDXR)

CSAB:

103243070(FDXR)

CATY:

105577757(FDXR)

PANU:

101020542(FDXR)

TGE:	112609261(FDXR)

MLEU:

105536177(FDXR)

RRO:	104681334(FDXR)

RBB:	108537405(FDXR)

TFN:	117066650(FDXR)

PTEH:

111542443(FDXR)

CANG:

105510761(FDXR)

CJC:	100385090(FDXR)

SBQ:	101045800(FDXR)

CIMI:

108309384(FDXR)

ANAN:

105718143(FDXR)

CSYR:

103275936(FDXR)

MMUR:

105878913(FDXR)

LCAT:

123650765(FDXR)

PCOQ:

105824769(FDXR)

OGA:	100954175(FDXR)

MMU:	14149(Fdxr)

MCAL:

110304577(Fdxr)

MPAH:

110331489(Fdxr)

RNO:	79122(Fdxr)

MCOC:

116078535(Fdxr)

ANU:	117710860(Fdxr)

ASYL:

127694991(Fdxr)

MUN:	110547618(Fdxr)

CGE:	100773278(Fdxr)

MAUA:

101825914(Fdxr)

PROB:

127219032(Fdxr)

PLEU:

114707045(Fdxr)

MORG:

121436197(Fdxr)

MFOT:

126500350

AAMP:

119813508(Fdxr)

NGI:	103732755(Fdxr)

HGL:	101700719(Fdxr)

CPOC:

100721684(Fdxr)

CCAN:

109687573(Fdxr)

DORD:

106002890(Fdxr)

DSP:	122128385(Fdxr)

PLOP:

125366014(Fdxr)

NCAR:

124980011

MMMA:

107157806(Fdxr)

ITI:	101976564(Fdxr)

OCU:

103346270

OPI:	101536356(FDXR)

TUP:	102478703(FDXR)

GVR:	103603696 103603699

CFA:	475910(FDXR)

CLUD:

112672774(FDXR)

VVP:	112920775(FDXR)

VLG:	121472516(FDXR)

NPO:	129496145(FDXR)

AML:	100475805(FDXR)

UMR:	103665719(FDXR)

UAH:	113244659(FDXR)

UAR:	123803103(FDXR)

ELK:

111160367

LLV:

125087856

MPUF:

101672223(FDXR)

MNP:	132003454(FDXR)

MLK:	131816440(FDXR)

NVS:	122906010(FDXR)

ORO:	101368875(FDXR)

EJU:	114216040(FDXR)

ZCA:	113908199(FDXR)

MLX:	118024294(FDXR)

NSU:	110572537(FDXR)

LWW:	102735119(FDXR)

FCA:	101096022(FDXR)

PYU:	121017886(FDXR)

PCOO:

112864494(FDXR)

PBG:	122485872(FDXR)

PVIV:

125151650(FDXR)

LRUF:

124513440

LGF:	123604535(FDXR)

AJU:

106987731

PTG:	102959508(FDXR)

PPAD:

109276964(FDXR)

PUC:

125926394

PLEZ:

122206828(FDXR)

HHV:	120228302(FDXR)

BTA:	282604(FDXR)

BOM:	102273000(FDXR)

BIU:	109574321(FDXR)

BBUB:

102396511(FDXR)

BBIS:

105000328(FDXR)

CHX:	102174063(FDXR)

OAS:	101111818(FDXR)

BTAX:

128064941(FDXR)

CSUM:

138083252(FDXR)

ODA:	120866713(FDXR)

CCAD:

122435751(FDXR)

MREE:

136149092(FDXR)

OVR:	110124257(FDXR)

MBEZ:

129544746(FDXR)

SSC:	100512919(FDXR)

CFR:	102519985(FDXR)

CBAI:

105065675(FDXR)

CDK:	105104618(FDXR)

VPC:	102528216(FDXR)

BACU:

103000856(FDXR)

BMUS:

118887494(FDXR)

LVE:	103086167(FDXR)

OOR:	101286717(FDXR)

LALB:

132511707(FDXR)

DLE:	111182857(FDXR)

PCAD:

102975384(FDXR)

PSIU:

116746140(FDXR)

NASI:

112410319(FDXR)

ECB:	100060312(FDXR)

EPZ:	103546558(FDXR)

EAI:	106830270(FDXR)

MYB:	102263706(FDXR)

MYD:	102766204(FDXR)

MMYO:

118672349(FDXR)

MDT:	132219067(FDXR)

MYUM:

138994581(FDXR)

PKL:	118704604(FDXR)

EFUS:

103298308(FDXR)

MNA:	107542925(FDXR)

DRO:	112298790(FDXR)

SHON:

119000882(FDXR)

AJM:	119065328(FDXR)

PDIC:

114503959(FDXR)

PHAS:

123817412(FDXR)

MMF:	118634177(FDXR)

PPAM:

129086617(FDXR)

HAI:	109383628(FDXR)

RFQ:	117014091(FDXR)

PALE:

102883561(FDXR)

PGIG:

120600057(FDXR)

PVP:	105293334(FDXR)

RAY:	107503798(FDXR)

MJV:	108385937(FDXR)

TOD:	119231766(FDXR)

SARA:

101545870(FDXR)

SFUM:

130045491(FDXR)

SETR:

126003664(FDXR)

LAV:	100655948(FDXR)

TMU:

101340285

ETF:	101638178(FDXR)

DNM:	101428033(FDXR)

MDO:	100027953(FDXR)

GAS:	123243625(FDXR)

SHR:	100922569(FDXR)

AFZ:

127560497

PCW:	110219324(FDXR)

TVP:	118848925(FDXR)

PBRV:

138152546(FDXR)

OAA:	100083234(FDXR)

TACU:

119921993(FDXR)

GGA:	769635(FDXR)

PCOC:

116232376(FDXR)

MGP:	100540404(FDXR)

CJO:	107322365(FDXR)

TPAI:

128083097(FDXR)

LMUT:

125702229(FDXR)

NMEL:

110407353(FDXR)

APLA:

101800804(FDXR)

ACYG:

106034619(FDXR)

CATA:

118253865(FDXR)

AFUL:

116496631(FDXR)

TGU:	100220739(FDXR)

LSR:	110484683(FDXR)

SCAN:

103819990(FDXR)

PMOA:

120505605(FDXR)

OTC:	121338456(FDXR)

PRUF:

121363875(FDXR)

ATRC:

139602668(FDXR)

GFR:	102034179(FDXR)

FAB:	101817164(FDXR)

OMA:	130260567(FDXR)

PHI:	102103074(FDXR)

PMAJ:

107212633(FDXR)

CCAE:

111937336(FDXR)

CCW:	104694370(FDXR)

CBRC:

103621792(FDXR)

ACOE:

138119957(FDXR)

ETL:	114063398(FDXR)

ZAB:	102071030(FDXR)

ZLE:	135455423(FDXR)

ACHL:

103803595(FDXR)

SVG:	106854292(FDXR)

MMEA:

130584408(FDXR)

HRT:	120761072(FDXR)

SATI:

136369244(FDXR)

CCIC:

134052012(FDXR)

FPG:	101910552(FDXR)

FCH:	102046860(FDXR)

CCRI:

104166718(FDXR)

NNT:	104411582(FDXR)

SHAB:

115616815(FDXR)

ACUN:

113486780(FDXR)

TALA:

104358298(FDXR)

ACHC:

115340983(FDXR)

HALD:

104323368(FDXR)

HLE:	104839155(FDXR)

AGEN:

126044094

HHAR:

128151199(FDXR)

GCL:

127024097

CSTI:

104554946(FDXR)

LDI:	104345645(FDXR)

MNB:	103781029(FDXR)

DPUB:

104302379(FDXR)

PPUS:

135179363(FDXR)

AVIT:

104270044(FDXR)

BRHI:

104495037(FDXR)

EGZ:	104125332(FDXR)

NNI:	104020721(FDXR)

PCRI:

104039008(FDXR)

PCAO:

104046890(FDXR)

PADL:

103916762(FDXR)

AFOR:

103899261(FDXR)

FGA:	104082427(FDXR)

GSTE:

104258724(FDXR)

CLV:	102085677(FDXR)

PGUU:

104466846(FDXR)

PLET:

104627201(FDXR)

EHS:	104514774(FDXR)

CMAC:

104487772(FDXR)

CUCA:

104062016(FDXR)

TEO:	104375299(FDXR)

BREG:

104640164(FDXR)

OHA:	104337043(FDXR)

ACAR:

104532532(FDXR)

CPEA:

104393259(FDXR)

CVF:	104281997(FDXR)

RTD:	128918086(FDXR)

CRID:

134523425(FDXR)

AAM:	106492601(FDXR) 106492602 106492733

AROW:

112977774(FDXR)

NPD:	112953746(FDXR)

TGT:	104569086(FDXR)

DNE:	112982609(FDXR)

SCAM:

104146707(FDXR)

ASN:	102373045(FDXR)

AMJ:	102563408(FDXR)

CPOO:

109315044(FDXR)

GGN:	109297817(FDXR)

PSS:	102459685(FDXR)

CMY:	102935912(FDXR)

CCAY:

125621306(FDXR)

DCC:	119843128(FDXR)

CPIC:

101952957(FDXR)

TST:	117887450(FDXR)

CABI:

116827506(FDXR)

MRV:	120383750(FDXR)

ACS:	100559841(fdxr)

ASAO:

132768645(FDXR)

PVT:	110085820(FDXR)

SUND:

121923234(FDXR)

PBI:	103051603(FDXR)

PMUR:

107286655(FDXR)

CTIG:

120307765(FDXR)

TSR:	106545931 106545932

PGUT:

117660538(FDXR)

APRI:

131191996(FDXR)

PTEX:

113437245(FDXR)

NSS:	113411936(FDXR)

VKO:	123035599(FDXR)

PMUA:

114590579(FDXR)

PRAF:

128407453(FDXR)

ZVI:	118079804(FDXR)

HCG:	128346131(FDXR)

GJA:	107110041(FDXR)

STOW:

125429332(FDXR)

EMC:	129328130(FDXR)

XLA:	108702801(fdxr.S) 495142(fdxr.L)

XTR:	100158651(fdxr)

NPR:	108797020(FDXR)

RTEM:

120919227(FDXR)

BBUF:

121003808(FDXR)

BGAR:

122941203(FDXR)

PWL:	138245975(FDXR)

MUO:	115473395(FDXR)

GSH:	117368249(FDXR)

DRE:	100536115(fdxr)

SRX:

107711271

SANH:

107667767(fdxr)

SGH:	107567808(fdxr)

CAUA:

113111369 113112143

CGIB:

127968814

PTET:

122333545(fdxr)

LROH:

127174436(fdxr)

OMC:

131551355

PPRM:

120474779(fdxr)

RKG:	130104191(fdxr)

MAMB:

125255565(fdxr)

CIDE:

127523262

CERY:

137007640(fdxr)

MASI:

127427344

TROS:

130569446(fdxr)

TDW:	130438797(fdxr)

MANU:

129420603(fdxr)

PDAB:

135743133 135757661

IPU:

108273819

IFU:	128616604(fdxr)

PHYP:

113527239(fdxr)

SMEO:

124389159(fdxr)

TFD:	113634073(fdxr)

TVC:	132862898(fdxr)

CGAR:

128541741(fdxr)

NGRA:

132898580(fdxr)

TRN:	134321237(fdxr)

AMEX:

103025034(fdxr)

CMAO:

118809110(fdxr)

EEE:	113581986(fdxr)

CHAR:

105896458(fdxr)

SPIL:

134077024(fdxr)

TRU:	101073938(fdxr)

TFS:	130538733(fdxr)

TNG:	GSTEN00035971G001

LCO:	104924915(fdxr)

TBEN:

117497660(fdxr)

CGOB:

115025087(fdxr)

PGEO:

117464891(fdxr)

GACU:

117556287(fdxr)

EMAC:

134870834(fdxr)

ELY:	117246627(fdxr)

EFO:	125880890(fdxr)

PLEP:

121958830(fdxr)

SLUC:

116044121(fdxr)

ECRA:

117937394(fdxr)

ESP:	116671122(fdxr)

PFLV:

114548398(fdxr)

GAT:	120819766(fdxr)

PPUG:

119213247(fdxr)

AFB:	129091503(fdxr)

CLUM:

117749181(fdxr)

PSWI:

130203896(fdxr)

CANA:

137790031(fdxr)

MSAM:

119915736(fdxr)

SCHU:

122867900(fdxr)

CUD:	121528941(fdxr)

SPUL:

138593674(fdxr)

LMIX:

132955383(fdxr)

ALAT:

119010381(fdxr)

ASTR:

137588268(fdxr)

MZE:	101468891(fdxr)

ONL:	100692854(fdxr)

OAU:	116330888(fdxr)

OLA:	101160395(fdxr)

OML:	112153832(fdxr)

CSAI:

133419444(fdxr)

XMA:	102233690(fdxr)

XCO:	114152171(fdxr)

XHE:	116727179(fdxr)

PRET:

103481952(fdxr)

PFOR:

103144068(fdxr)

PLAI:

106935294(fdxr)

PMEI:

106927044(fdxr)

GAF:	122822968(fdxr)

PPRL:

129377598(fdxr)

CVG:	107098006(fdxr)

CTUL:

119792610(fdxr)

GMU:	124874696(fdxr)

NFU:	107388287(fdxr)

KMR:	108235827(fdxr)

ALIM:

106532010(fdxr)

NWH:	119424135(fdxr)

AOCE:

111570558(fdxr)

EJA:	138202287(fdxr)

BFRE:

138626063(fdxr)

MCEP:

125022874(fdxR)

CSEM:

103382155(fdxr)

POV:	109627156(fdxr)

SSEN:

122761442(fdxr)

SSOE:

131448884(fdxr)

HHIP:

117752942(fdxr)

HSP:	118100873(fdxr)

PPLT:

128427172(fdxr)

SMAU:

118287844(fdxr)

LCF:	108872584 108891381

SDU:	111220293(fdxr)

SLAL:

111656400(fdxr)

XGL:	120794728(fdxr)

HCQ:	109513310(fdxr)

SSCV:

125991656(fdxr)

SBIA:

133495790(fdxr)

PEE:	133417821(fdxr)

PTAO:

133469154(fdxr)

BPEC:

110155172(fdxr)

ENY:	140368862(fdxr)

MALB:

109974910(fdxr)

BSPL:

114845300(fdxr)

SJO:	128381221(fdxr)

SSCO:

134003245(fdxr)

GMH:	115530717(fdxr)

SASA:

106589468(fdxr)

STRU:

115201249(fdxr)

OTW:	112224341(fdxr)

OMY:	110498918(fdxr)

OGO:	124040097(fdxr)

ONE:	115144117(fdxr)

OKI:	109870094(fdxr)

OKE:	118357414(fdxr)

OMM:	135523771(fdxr)

OCLA:

139376646

SALP:

111967841(fdxr)

SNH:	120029593(fdxr)

CCLU:

121547404(fdxr)

ELS:	105023035(fdxr)

OEP:	134031862(fdxr)

SFM:	108940168(fdxr)

PKI:	111856706(fdxr)

AANG:

118220787(fdxr)

AROT:

135248523(fdxr)

CCOG:

133121953(fdxr)

LOC:	102694558(fdxr)

PSPA:

121295694(fdxr)

ARUT:

117423501(fdxr)

PSEX:

120518046(fdxr)

LCM:	102360919(FDXR)

CMK:	103175676(fdxr)

RTP:

109915687

CPLA:

122562010(fdxr)

HOC:	132827672(fdxr)

LERI:

129708384(fdxr)

PMRN:

116949711(FDXR)

LRJ:	133345283(FDXR)

BFO:

118429621

BBEL:

109462868

CIN:

100177510

SCLV:

120332274

SPU:	115926669 585224

LPIC:

129269930

AJJ:

139959481

APLC:

110979675

ARUN:

117292868

AAMU:

139944322

AFIL:

140151412

AJC:

117099883

SKO:

100373097

PFLL:

139151105

DME:	Dmel_CG12390(dare)

DER:

6547275

DSE:

6608632

DSI:	Dsimw501_GD15255(Dsim_GD15255)

DYA:	Dyak_GE13030

DAN:

6495267

DSR:

110179307

DPO:

4804748

DPE:

6593215

DMN:

108158913

DWI:

6640149

DGR:

6559698

DMO:	Dmoj_GI19640

DAZ:

108616356

DNV:

108654263

DHE:

111605262

DVI:	116650969 6636403

CCAT:

101462478

BOD:

106616455

BDR:

105224627

RZE:	108363882 108381884

AOQ:

129243960

ALUD:

128868188

TDA:	119678481 119683911

MDE:

101888739

SCAC:

106086506

LCQ:

111684762

LSQ:

119609448

CVJ:	135960190(dare)

GFS:

119641541

ECOE:

129952551

CLON:

129610778

HIS:

119646356

AGA:

1276117

ACOZ:

120950972

AARA:

120896429

AMER:

121592385

ASTE:

118509931

AMAP:

126562129

AFUN:

125767934

AMOU:

128302099

AMRS:

128713149

AALI:

118463030

ACOS:

131262841

AAG:

5568320

AALB:

109406573 109427156

ASUA:

134204538 134209568

CPII:

120430090

CNS:

116352382

BCOO:

119070231 119075123

LLL:

129791905

PPAP:

129801235

AME:

100578109

ACER:

108001938

ALAB:

122717809

ADR:

102671572

AFLR:

100866482

BIM:

100742822

BBIF:

117206102

BVK:

117235515

BVAN:

117154032

BHUN:

126864615

BTER:

100643757

BAFF:

126916837

BPYO:

122565615

BPAS:

132905140

FVI:

122532495

CCAL:

108633071

OBB:

114874960

MGEN:

117218674

NMEA:

116430631

CGIG:

122398425 122403102

SOC:

105198930

MPHA:

105836465

AEC:

105148416

ACEP:

105619099

PBAR:

105433423

VEM:

105570573

COBS:

139109416 139112833

HST:

109503578

DQU:

106747100

CFO:

105259167

FEX:	115242894 115242899

PMEC:

138933844(Dare)

PGC:

109852590

PCF:

106793805

PFUC:

122520259

VCRB:

124426943

VVE:

124952578

NVI:

100118934

CSOL:

105368694

MDL:

103572848

CGLO:

123273051

FAS:

105264277

DAM:

107038102

AGIF:

122847677

CINS:

118074058

VCAN:

122410480

DSM:

124407505

NLO:

107219211

TCA:

658878

TMOL:

138136459(dare)

DPA:

109543924

ESIM:

136415146(dare)

EFOR:

136345399(dare)

SOY:

115888844

AGRG:

126741072

ATD:

109601100

CSET:

123314714

HAXR:

123676300

AGB:

108905929

LDC:

111511306

DVV:

114333461

NVL:

108559754

APLN:

108739053

PPYR:

116163196

OTU:

111413648

BMOR:

101736047

BMAN:

114239482

MSEX:

115441839

DPL:	KGM_204482

MJU:

123864585

VCD:

124537035

MCIX:

123665197

PMAC:

106720445

PPOT:

106107913

PXU:

106117116

BPHI:

137929618(dare)

PRAP:

110993775

PNAP:

125055686

ZCE:

119829897

CCRC:

123699466

LSIN:

126965696

AAGE:

121729447

HAW:

110371243

HZE:

124642221

TNL:

113492602

SLIU:

111357308

OFU:

114355679

ONU:

135081382

ATRA:

106138700

GMW:

113522504

PXY:

105386739

PGW:

126375110

LGLY:

125231113

CSTB:

134746804

CCRN:

123291899

API:

100163608

DNX:

107162313

AGS:

114126519

RMD:

113554625

ACOO:

126840484

DVT:

126903843

BTAB:

109032385

DCI:

103514046

CLEC:

106666428

HHAL:

106687599(dare)

NLU:	111054427 120348716

HVI:

124354552

MQU:	128999927 129000771

PHU:	Phum_PHUM454900

FOC:

113208229

TPAL:

117649998

ZNE:

110840377

CSEC:

111871196

SGRE:

126334725

BROR:

134541128

IEL:

124173542

HAMR:

139688621(dare)

FCD:

110859784

DPX:	DAPPUDRAFT_307619

DMK:

116916702

DPZ:

124329320

AFRA:

136031733 136031974

PVM:	113809333(dare)

PJA:

122254655

PCHN:

125030726

PMOO:

119576053

HAME:

121854763 121858074 121860451

PCLA:

123755457(dare)

CQD:	128691869(dare)

PTRU:

123503565

ESN:

127002674

MRJ:	136828828(dare)

PORN:

139764519(dare)

HAZT:

108672593

EAF:	111695764 111699508

LSM:	121124063(dare)

TCF:

131880153

PPOI:

119098041

DSV:

119453255

RSAN:

119399879

RMP:

119179512

VDE:

111249722

VJA:

111264312

TUT:

107367827

DPTE:

113791405

DFR:

124493886

CSCU:

111627093

CVS:	136976949(dare)

PTEP:

107452720

ABRU:

129965433

UDV:

129234148

SDM:

118181505

LPOL:

106458702

PMEO:

129594532 129600182

CEL:	CELE_Y62E10A.6(Y62E10A.6)

CBR:

CBG_01781

CRQ:	GCK72_014540

NAI:	NECAME_04632

BMY:	BM_BM13917(Bm13917)

LOA:	LOAG_17415

TSP:

Tsp_06076

HRO:	HELRODRAFT_156059

LGI:	LOTGIDRAFT_229321

PVUL:

126811790

PCAN:

112560575

LSAX:

138959742

GAE:	121379228 121392794

HRF:

124141168

HRJ:

124259830

HASI:

137285106

HCRA:

139469000

CRG:

117684275

CANU:

128164472

CVN:

111119152

OED:

125668084

MYI:

110450206

PMAX:

117329840

AIRR:

138323967

MCAF:

127709042

MMER:

123563669

RPHI:

132755992

DPOL:

127866137

MAEA:

128203301

OBI:

106882139

OSN:

115211965

LJP:

135466751

LAK:

106177774

SMM:	Smp_166580

SHX:	MS3_00003030

OVI:	T265_04536

EGL:

EGR_04544

LLON:

135493547

NVE:	5499700 5516900

EPA:

110242963

ATEN:

116293028

ADF:	107341444 107341462

AMIL:

114959441

MCAZ:

138060164

MFOO:

137971039

PDAM:

113679324

SPIS:

111321589

DGT:	114539459 114541708 114544099

XEN:

124448472

HMG:

100200068

HSY:

130648399

RES:

135683010

TAD:	TRIADDRAFT_21502

AQU:

100637039

ATH:

AT4G32360

ALY:

9305351

CRB:

17880727

CSAT:

104716945 104721596 104730035

EUS:	EUTSA_v10013379mg

BRP:

103864869

BNA:	106366392 106406693

BOE:

106318680

RSZ:

108828206

THJ:

104799066

CPAP:

110818598

CIT:

102628424

CIC:	CICLE_v10008139mg

PVY:

116130548

MINC:

123193844

TCC:

18588561

GRA:

105787215

GHI:	107930784 107932944

GAB:

108469395

HSYR:

120149893

DZI:

111285736

EGR:

104438256

RARG:

115749142

GMX:	100777997 100783738

GSJ:	114385187 114413570

PVU:

137812860

VRA:

106765554

VAR:

108346262

VUN:

114175841

VUM:

124837376

CCAJ:

109804194

APRC:

113853785

MTR:

11409614

TPRA:

123915479

CAM:

101500867

PSAT:

127105309

VVO:

131603852

LJA:

130715054

ADU:

107478608

AIP:

107630280

AHF:	112738090 112790228

LANG:

109349811

PCIN:

129292929

QSA:	O6P43_026000 O6P43_032363

FVE:

101302840

AANS:

126793392

RCN:

112183297

PPER:

18770919

PMUM:

103340886

PAVI:

110751001 110771640

PDUL:

117633762 117633763

MDM:

103449468

MSYL:

126595740

PXB:	103929399 103943868

PCOX:

137744113 137748164

ZJU:

107431953

MNT:

21384088

CSAV:

115708329

CSV:

101208191

CMO:

103483451

BHJ:

120092438

MCHA:

111016072

CMAX:

111479698

CMOS:

111432190

CPEP:

111790949

RCU:

8262557

MEAN:

126668759

JCU:

105637751

HBR:

110664984

MESC:

110607306

POP:

18099452

PEU:

105123410

PALZ:

118029760

PNZ:

133670413

JRE:

109011855

CILL:

122308256

CAVE:

132165615

AGLU:

133857307

QSU:

111987573

QLO:

115963994

TWL:	119986565 120016632

VVI:

100252665

VRI:

117925737

SLY:

101245589

SPEN:

107008435

SOT:

102598661

SSTN:

125877685

SDUL:

129886003

CANN:

107839770

LBB:

132598540

NTA:	107792906 107824272

NSY:

104228460

NTO:

104098479

NAU:

109232877

INI:

109153160

ITR:	116004665 116027973

SIND:

105168712

OEU:

111398852

EGT:

105950489

SSPL:

121755604 121797234

SMIL:

130992134

SHIS:

125205221

APAN:

127260066

HAN:

110928552

ECAD:

122599885

LSV:

111883878

CCAV:

112500083

DCR:

108214615

CSIN:

114320893

RVL:

131320143

AEW:

130784458

DLT:

127794991

BVG:

104902247

SOE:

110799347

CQI:	110690987 110707744

ATRI:

130824615

MOF:

131158363

NNU:

104595144

MING:

122067048

TSS:

122670322

PSOM:

113348251 113349110

OSA:

4329009

DOSA:

Os02g0277600

OBR:

102699565

OGL:

127762102

BDI:

100845899

ATS:

109777158

TDC:	119267402 119275292

TAES:

123060549 123069114 123077636

LPER:

127296073

LRD:	124649256 124708326

SBI:

8060381

ZMA:	100285690 109946101 109946102

MFLO:

136463218 136476218 136532364

SITA:

101765991 101778888

SVS:	117833857 117859322

PVIR:

120655383 120697800

PHAI:

112887846

PAUA:

133922283

PDA:

103702547

EGU:

105040853

MUS:

103987769

ZOF:	122041213 122045713

DCT:

110095192

PEQ:

110021011

AOF:	109828292 109850991

MSIN:

131257455

ACAK:

137941684

NCOL:

116256492

ATR:

18426683

CJF:

131061576

SMO:	SELMODRAFT_129828 SELMODRAFT_77880

PPP:

112287080

CRE:	CHLRE_13g562550v5

VCN:	VOLCADRAFT_79700

MNG:

MNEG_2646

CSL:	COCSUDRAFT_19462

CVR:	CHLNCDRAFT_34805

APRO:

F751_5995

OLU:	OSTLU_2735 OSTLU_2736

OTA:	OT_ostta13g02090

BPG:	Bathy17g01130

MIS:	MICPUN_112691

MPP:	MICPUCDRAFT_44415

CME:	CYME_CMM294C

GSL:	Gasu_05350

SCE:	YDR376W(ARH1)

SEUB:

DI49_0553

SPAO:

SPAR_D05650

AGO:	AGOS_ACR202W

ERC:

Ecym_4641

KLA:	KLLA0_E02531g

KMX:	KLMA_20603(ARH1)

LTH:	KLTH0F15664g

VPO:	Kpol_1062p16

ZRO:	ZYRO0G01760g

CGR:	2886446(GVI51_A02827)

NCS:	NCAS_0A11790(NCAS0A11790)

NDI:	NDAI_0A04500(NDAI0A04500)

TPF:	TPHA_0E01640(TPHA0E01640)

TBL:	TBLA_0A02700(TBLA0A02700)

TGB:	HG536_0F02650

TDL:	TDEL_0D02510(TDEL0D02510)

KAF:	KAFR_0E03780(KAFR0E03780)

KNG:	KNAG_0C04840(KNAG0C04840)

ZMK:	HG535_0C04330

SLUD:

SCDLUD_003231

DHA:	DEHA2D18216g

PIC:	PICST_52035(ARH1)

PGU:	PGUG_05225

SPAA:

SPAPADRAFT_142046

LEL:	PVL30_004087(ARH1)

LBG:	92210211(LODBEIA_P50150)

CAL:	CAALFM_C204880CA(ARH2)

CTP:	CTRG_00032

COT:	CORT_0E01470

CDU:	CD36_19440

CTEN:

18249215(ARH1)

CLU:	CLUG_03073

CLUS:

A9F13_12g00902

CAUR:

CJI96_0001563

ASAU:

88173202(PUMCH_002137)

PPA:	PAS_chr3_0058

PKZ:	C5L36_0A09270

BNN:	FOA43_004710

BBRX:

BRETT_001693

OPA:	HPODL_02660

YLI:	2907349(YALI2_C00419g)

SLB:	AWJ20_604(ARH1)

NCR:

NCU08005

SMP:	10806281(SMAC4_01842)

PAN:	PODANSg7406

PBEL:

QC761_601370(ARH1)

PPSD:

QC762_601370(ARH1)

PPSP:

QC763_601370(ARH1)

PPSA:

QC764_601370(ARH1)

TTT:	THITE_2115057

MTM:	MYCTH_2298661

CTHR:

CTHT_0034180

RTHE:

98126239(VTJ83DRAFT_5039)

MGR:

MGG_14814

PPEI:

PpBr36_01235

PGRI:

PgNI_03775

SSCK:

SPSK_09065

FGR:	FGSG_01927

FPU:	FPSE_09145

FPOA:

FPOAC1_002039

FVN:	FVRRES_02281

FVR:	FVEG_07324

FOX:	FOXG_04206

NHE:	NECHADRAFT_96798

FFC:	NCS54_01265900

FKR:	NCS57_01243600

FMU:	J7337_010669

TRE:	TRIREDRAFT_21553

TRR:	M419DRAFT_23559

TATV:

25784537(TrAtP1_005868)

TASP:

36612298(TrAFT101_005183)

MAW:	19252204(ARH1_1)

MAJ:

MAA_05280

MBRN:

26239178(G6M90_00g007750)

PCHM:

VFPPC_03516

CMT:

CCM_02929

AMUS:

LMH87_007013

PLJ:	28882757(PLICBS_001239)

PTKZ:

JDV02_008016(ARH1)

VAL:	VDBG_04332

VDA:	VDAG_09043

CFJ:	CFIO01_12734

CLUP:

CLUP02_14865

CHIG:

CH63R_04514

CDET:

87941574(CDEST_05071)

SAPO:

SAPIO_CDS0845

ELA:	UCREL1_3332

PFY:	PFICI_05619

SSL:	SS1G_07605

BFU:	BCIN_15g03520(Bcarh1)

MBE:

MBM_04149

PSCO:

LY89DRAFT_662331

GLZ:	GLAREA_04053

ANI:	ANIA_06272

AFM:	AFUA_2G12610

ACT:	ACLA_071500

NFI:	NFIA_087750

AOR:	AO090026000356

ANG:	An02g01540

AFV:	AFLA_005929

ALUC:

AKAW2_21481A(ARH1)

ACHE:

ACHE_40835A(ARH1)

APUU:

APUU_51210A(ARH1)

PCS:	N7525_009884

PDP:	PDIP_89010

POU:	POX_e07278

TMF:	EYB26_007272

TRG:	TRUGW13939_07084

CIM:	CIMG_05174

CPW:	9692992(ARH1)

URE:	UREG_06424

ABE:

ARB_04864

TVE:

TRV_06564

PBL:	PAAG_06230

PBN:	PADG_07017

AJE:	HCAG_03785

BGH:	BDBG_05560

PNO:	SNOG_05877

PTE:

PTT_11539

PTRR:

6343499(PtrM4_123120)

BZE:	COCCADRAFT_108572

BSC:	COCSADRAFT_200971

BOR:	COCMIDRAFT_9086

AALT:

CC77DRAFT_1021465

ADAC:

96086167(ACET3X_005845)

ARAB:

EKO05_0000806

ZTR:	MYCGRDRAFT_76370

PFJ:	MYCFIDRAFT_98106

FFU:	CLAFUR5_03172

CBET:

CB0940_03307

BCOM:

BAUCODRAFT_148388

NPA:	UCRNP2_9683

TML:	GSTUM_00002140001

SPO:	2541049(arh1)

SOM:	SOMG_00106(arh1)

CNE:

CNL05820

CNB:

CNBI1010

CNG:	CNAG_05035

CGI:	CGB_D1180W

CDEU:

CNBG_4647

CDEP:

91086860(L203_102649)

KMG:	30163393(I203_102596)

KNE:	92182383(IAR55_005125)

TMS:	TREMEDRAFT_27417

TASA:

A1Q1_02851

CCAC:

CcaHIS019_0305480(ARH1)

PPL:	POSPLDRAFT_22256

TVS:	TRAVEDRAFT_53347

DSQ:	DICSQDRAFT_87405

SHS:	STEHIDRAFT_81823

HIR:	HETIRDRAFT_480460

PSQ:	PUNSTDRAFT_18428

ADL:	AURDEDRAFT_109943

FME:	FOMMEDRAFT_30587

GTR:	GLOTRDRAFT_117158

RSX:	RhiXN_02181

LBC:	LACBIDRAFT_305530(LbAdr1)

CCI:	CC1G_02646

ABP:	AGABI1DRAFT77612(AGABI1DRAFT_77612)

ABV:	AGABI2DRAFT212328(AGABI2DRAFT_212328)

MPR:	MPER_07288

MRR:	Moror_9051

E1B28_004294

SCM:	SCHCO_02576903(SCHCODRAFT_02576903)

CPUT:

CONPUDRAFT_121157

SLA:	SERLADRAFT_448609

WSE:	WALSEDRAFT_56700

WIC:	J056_000029

UMA:	UMAG_11268

PFP:	PFL1_00914

SGRA:

EX895_006093

MGL:

MGL_1519

MRT:

MRET_3839

MSYM:

MSY001_2430

PGR:	PGTG_14061

PTRC:

PtA15_13A229

PSTR:

Pst134EA_030377 Pst134EA_030443

MLR:	MELLADRAFT_49489

ECU:	ECU11_1310

EIN:	Eint_111200

EHE:	EHEL_111200

ERO:	EROM_111200

NCE:	NCER_101292

RIE:	OCT59_004146

MBR:	MONBRDRAFT_16315

SRE:	PTSG_06531

DDI:	DDB_G0287353(fdxr)

DPP:	DICPUDRAFT_154647

DFA:	DFA_07524(fdxr)

ACAN:

ACA1_157880

PFA:	PF3D7_1139700

PFD:	PFDG_02656

PFH:	PFHG_02242

PREI:

PRSY57_1138100

PGAB:

PGSY75_1139700

PLAG:

39742624(PADL01_1137900)

PYO:	PY17X_0910700

PCB:	PCHAS_0710600

PBE:	PBANKA_0909300

PVV:	PVVCY_0903810

PKN:	PKNH_0937600

PVX:	PVX_092585 PVX_191290 PVX_192290 PVX_202290

PCY:	PCYB_094530

PMAL:

PMUG01_09048800

PBRS:

92371081(MKS88_002993)

PREL:

PRELSG_0937100

PCOT:

PCOAH_00027330

TAN:

TA15585

TPV:

TP02_0869

TOT:	TOT_020000888

BEQ:	BEWA_035770

BBO:	BBOV_I000680

BMIC:

BMR1_03g00286

BBIG:

BBBOND_0301040

CPV:

cgd8_2710

CHO:	Chro.80316

TGO:	TGME49_261030

BBES:

BESB_084930

TET:	TTHERM_00471929

PTM:	GSPATT00024587001

PTI:	PHATRDRAFT_43018

FCY:	FRACYDRAFT_246190

TPS:	THAPS_10895

NGD:	NGA_0622900

AAF:	AURANDRAFT_55426

PIF:	PITG_04837

PSOJ:

PHYSODRAFT_542020

SPAR:

SPRG_05062

TBR:	Tb10.70.5510

TBG:	TbgDal_X2700

TCR:	511367.230

LMA:	LMJF_21_0420

LIF:	LINJ_21_0480

LDO:	LDBPK_210480

LMI:	LMXM_21_0420

LMAT:

92514637(LSCM1_04626)

LBZ:	LBRM_21_0480

LPAN:

LPMP_210450

LOI:	92361623(LSCM4_05758)

LEIS:

94181083(GH5_05727)

LENR:

94173367(CUR178_06183)

LEIN:

94188894(JIQ42_05256)

PHET:

94291063(JKF63_05016)

NGR:	NAEGRDRAFT_77955

EHX:	EMIHUDRAFT_63841

GTT:	GUITHDRAFT_68762

MEJ:

Q7A_1971

NJP:	NEJAP_1757

RHY:	RD110_02870

RBM:

TEF_04445

NAR:

Saro_1433

NPP:	PP1Y_AT21299

NPN:	JI59_18995

NRE:	BES08_01875

NOV:	TQ38_011435

NOT:	C7W88_10620

NOR:	FA702_00920

NGF:	FRF71_10490

NOG:	GKE62_17515

SPHP:

LH20_18115

SMAG:

AN936_21405

SMAZ:

LH19_24840

STER:

AOA14_10640

SGI:	SGRAN_4025(fprA)

SPHO:

C3E99_16535

SPHI:

TS85_10655

SLUT:

H9L13_00335

SPHJ:

BSL82_01105

SPZR:

G5C33_08075

SMIC:

SmB9_03030

SPHS:

ETR14_13370

SAND:

H3309_03450

ALB:

AEB_P1581

ANH:	A6F65_01487(fprA)

CNA:	AB433_11840

ERY:	CP97_07920

NTD:	EGO55_01285

» show all

Reference

Authors

Omura T, Sanders E, Estabrook RW, Cooper DY, Rosenthal O.

Title

Isolation from adrenal cortex of a nonheme iron protein and a flavoprotein functional as a reduced triphosphopyridine nucleotide-cytochrome P-450 reductase.

Journal

Arch Biochem Biophys 117:660-673 (1966)

Reference

2 [PMID:4144106]

Authors

Chu JW, Kimura T

Title

Studies on adrenal steroid hydroxylases. Molecular and catalytic properties of adrenodoxin reductase (a flavoprotein).

Journal

J Biol Chem 248:2089-94 (1973)

Reference

3 [PMID:235468]

Authors

Sugiyama T, Yamano T

Title

Purification and crystallization of NADPH-adrenodoxin reductase from bovine adrenocortical mitochondria.

Journal

FEBS Lett 52:145-8 (1975)
DOI:10.1016/0014-5793(75)80658-2

Reference

4 [PMID:6766943]

Authors

Hanukoglu I, Jefcoate CR.

Title

Mitochondrial cytochrome P-450sec. Mechanism of electron transport by adrenodoxin.

Journal

J Biol Chem 255:3057-61 (1980)

Reference

5 [PMID:3011431]

Authors

Hanukoglu I, Hanukoglu Z

Title

Stoichiometry of mitochondrial cytochromes P-450, adrenodoxin and adrenodoxin reductase in adrenal cortex and corpus luteum. Implications for membrane organization and gene regulation.

Journal

Eur J Biochem 157:27-31 (1986)
DOI:10.1111/j.1432-1033.1986.tb09633.x

Reference

6 [PMID:2924777]

Authors

Hanukoglu I, Gutfinger T

Title

cDNA sequence of adrenodoxin reductase. Identification of NADP-binding sites in oxidoreductases.

Journal

Eur J Biochem 180:479-84 (1989)
DOI:10.1111/j.1432-1033.1989.tb14671.x

Sequence

[bta:282604]

Reference

7 [PMID:10369776]

Authors

Ziegler GA, Vonrhein C, Hanukoglu I, Schulz GE

Title

The structure of adrenodoxin reductase of mitochondrial P450 systems: electron transfer for steroid biosynthesis.

Journal

J Mol Biol 289:981-90 (1999)
DOI:10.1006/jmbi.1999.2807

Sequence

[bta:282604]

Other DBs

ExplorEnz - The Enzyme Database:

1.18.1.6

IUBMB Enzyme Nomenclature:

1.18.1.6

ExPASy - ENZYME nomenclature database:

1.18.1.6

BRENDA, the Enzyme Database:

1.18.1.6

All links

Gene (2452)   
   MGENES (629)   
   RefGene (1823)   
Protein sequence (4084)   
   UniProt (4030)   
   SWISS-PROT (10)   
   RefSeq(pep) (39)   
   PDBSTR (5)   
DNA sequence (127)   
   RefSeq(nuc) (66)   
   GenBank (30)   
   EMBL (31)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   InterPro (4)   
All databases (6669)   

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