KEGG ENZYME: 1.2.1.13

ENZYME: 1.2.1.13

Entry

EC 1.2.1.13                 Enzyme

Name

glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
triosephosphate dehydrogenase (NADP+);
dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
NADP+-glyceraldehyde-3-phosphate dehydrogenase;
NADP+-glyceraldehyde phosphate dehydrogenase;
NADP+-dependent glyceraldehyde phosphate dehydrogenase;
NADP+-triose phosphate dehydrogenase;
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
GAPDH

Class

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

Sysname

D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)

Reaction(IUBMB)

D-glyceraldehyde 3-phosphate + phosphate + NADP+ = 3-phospho-D-glyceroyl phosphate + NADPH + H+ [RN:R01063]

Reaction(KEGG)

R01063

Substrate

D-glyceraldehyde 3-phosphate [CPD:C00118];
phosphate [CPD:C00009];
NADP+ [CPD:C00006]

Product

3-phospho-D-glyceroyl phosphate [CPD:C00236];
NADPH [CPD:C00005];
H+ [CPD:C00080]

History

EC 1.2.1.13 created 1961

Pathway

ec00710

Carbon fixation by Calvin cycle

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K05298

glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)

Genes

ATH:	AT1G12900(GAPA-2) AT1G42970(GAPB) AT3G26650(GAPA)

ALY:	9311398 9326040 9327306

CRB:	17885995 17897550 17898235

CSAT:

104710464 104739945 104755567 104757901 104771836 104777631 104779875

EUS:	EUTSA_v10004217mg EUTSA_v10004349mg EUTSA_v10007809mg

BRP:	103833307 103843097 103871970 103875281

BNA:	106346458 106349325 106361259 106367141 106400630 106400839 106405503 106409666 106412548

BOE:	106295615 106305800 106308443 106311773 106319595

RSZ:	108805608 108810222 108812248 108822559 108854059 130504155

THJ:	104805297 104813182 104825726

CPAP:

110813067 110818294

CIT:	102614495 102626680

CIC:	CICLE_v10001114mg CICLE_v10015476mg

PVY:	116128630 116146945

MINC:

123195489 123202720 123224567

TCC:	18591736 18601182

GRA:	105769022 105770131 105776635 105783386

GHI:	107897324 107905717 107905755 107914182 107917007 107922459 107934914 107935841

GAB:	108450694 108468831 108480988 108489241

HSYR:

120118653 120147744 120159417 120169541 120185813 120190340 120198658 120209850 120212505

DZI:	111280876 111292190 111300461 111311440

EGR:	104419073 104448945

GMX:	100806482 100815649 732571 732655

GSJ:	114390372 114399964 114408495 114414517

PVU:	PHAVU_001G098100g PHAVU_009G006600g

VRA:	106753937 106762331

VAR:	108329548 108341301

VUN:	114162988 114163307

VUM:	124831520 124832874

CCAJ:

109791812 109802348

APRC:

113860768 113865873 113866973

MTR:	11428156 11437530

TPRA:

123889407 123899267

CAM:	101493610 101505130

PSAT:

127087680 127126703

VVO:	131596304 131609872 131660350

LJA:	130729162 130729822

ADU:	107460215 107494551

AIP:	107604910 107608243 107609606

AHF:	112697048 112705728 112754934 112764375 112785096 112785966

LANG:

109335833 109344011 109347482 109352140 109358522

PCIN:

129286859 129300698

QSA:	O6P43_009786 O6P43_016380 O6P43_018788

FVE:	101296006 101307033

RCN:	112177102 112188936

PPER:

18776538 18784386

PMUM:

103330412 103336651

PAVI:

110764330 110768177

PDUL:

117612470 117627459

MDM:	103409404 103425757 103442070

MSYL:

126610959 126626403 126634129

PXB:	103936989 103952908 103961743 103966613

ZJU:	107419772 107427982

MNT:	21390976 21407558

CSAV:

115701450

CSV:	101202856(GAPDH) 101205112

CMO:	103491694 103493832

BHJ:	120081786 120086996

MCHA:

111007569 111016929

CMAX:

111474421 111480365 111481957 111486674

CMOS:

111435144 111442251 111442776 111446791

CPEP:

111785270 111791267 111792213 111797116

RCU:	8273055 8273642

MEAN:

126660134 126681022

JCU:	105630249 105635196

HBR:	110639836 110648087 110654413 110669260

MESC:

110607108 110613869 110615648 110626980

POP:	112326437 7457998 7474559 7494712

PEU:	105110306 105132106 105132825 105137219

PALZ:

118041836 118042057 118044122 118061901

PNZ:	133682745 133691287 133692630 133694634

JRE:	108997409 109006695 109011490 109022238

CILL:

122311510 122313310 122317351 122317760

CAVE:

132178499 132178784 132190442

QSU:	112016160 112023637

QLO:	115974679 115976310 115981991

TWL:	119993625 119997268 119999232 120008911

VVI:	100246378 100259814

VRI:	117907541 117931339

SLY:	101249445 101253541 101264004 101266713

SPEN:

107007123 107011213 107017598 107017638

SOT:	102587206 102605252 102606161

SSTN:

125854512 125856815 125862523 125862814

SDUL:

129869982 129874292 129881645 129904335

CANN:

107851146 107866774 107870368 107877699

LBB:	132604190 132613886 132621892

NTA:	107767301 107777241 107780142 107796678 107801158 107820790

NSY:	104229906 104234464 104246338

NTO:	104092088 104119702 104120913

NAU:	109206719 109224788 109232207

INI:	109162850 109181961 109184523

ITR:	115996603 116006964 116032742

SIND:

105156113 105158872

OEU:	111380808 111405940

EGT:	105953652 105960013

SSPL:

121755158 121755759 121759083 121759957 121763941 121767243 121772439 121792902 121809421

SMIL:

130995145 131011003

SHIS:

125205609 125212993 125220045 125222363

APAN:

127247017 127257232 127260377

HAN:	110912668 110920787 110940865

ECAD:

122590218 122596564

LSV:	111886224 111921246

CCAV:

112509283 112522570

DCR:	108203025 108205052 108219447 108227329

CSIN:

114278733 114286729

RVL:	131311878 131330807 131333620

AEW:	130772220 130775988 130786580 130787535 130792188

BVG:	104901009 104907408

SOE:	110790548 110805429

CQI:	110685524 110700727 110711214

ATRI:

130810419 130817321 130828347

MOF:	131144468 131162229

NNU:	104591924 104592682 104606825

MING:

122077567 122077761 122083679

TSS:	122654156 122659946

PSOM:

113271433 113281293 113289632 113298929

OSA:	4331495 4336044

OBR:	102704595 102711250

OGL:	127765529 127770523

BDI:	100829538 100846055

ATS:	109754470 109783816

TDC:	119291849 119303962 119355368 119364491

TAES:

123045658 123053529 123093580 123098850 123105786 123189421

TUA:

125538674

LPER:

127297220 127335113

LRD:	124673959 124701300

SBI:	110431784 110436299

ZMA:	103641723 103642790 109943118 542290 542368

MFLO:

136449878 136449908 136490706 136495436 136535734 136552367

SITA:

101752582 101774537

SVS:	117837837 117863891

PVIR:

120642289 120647441 120681642 120688311

PHAI:

112875455 112899553

PDA:	103704929 103712351

EGU:	105042746 105050991 105060347

MUS:	103970142 103972115 103987962 104000636

ZOF:	121980909 121984799 122041998 122046512

DCT:	110100469 110101371

PEQ:	110033351 110036777 110037744

AOF:	109823666 109836656

MSIN:

131236991 131239228

NCOL:

116247479 116257530 116261011

ATR:	18434583 18445484

SMO:	SELMODRAFT_179517 SELMODRAFT_181561 SELMODRAFT_270825 SELMODRAFT_271457

PPP:	112277549 112278729 112284651 112284729 112286028 112288602

CRE:	CHLRE_01g010900v5

VCN:	VOLCADRAFT_76662

CSL:	COCSUDRAFT_38051

CVR:	CHLNCDRAFT_49269

APRO:

F751_4740

OLU:	OSTLU_28757 OSTLU_37993

OTA:	OT_ostta01g01560 OT_ostta10g03420

BPG:	Bathy01g01370 Bathy11g03690

MIS:	MICPUN_104695(GAPB) MICPUN_104876(GAPA)

MPP:	MICPUCDRAFT_25339(GAPDH_5) MICPUCDRAFT_49403(GAPDH_3)

CME:	CYME_CMJ042C

GSL:	Gasu_48130

CCP:	CHC_T00009438001

» show all

Reference

1 [PMID:13804190]

Authors

BRENNEMAN FN, VOLK WA.

Title

Glyceraldehyde phosphate dehydrogenase activity with triphosphopyridine nucleotide and with diphosphopyridine nucleotide.

Journal

J Biol Chem 234:2443-7 (1959)

Reference

Authors

Gibbs M.

Title

TPN triosephosphate dehydrogenase from plant tissue.

Journal

Methods Enzymol 1:411-415 (1955)

Reference

3 [PMID:13271400]

Authors

ROSENBERG LL, ARNON DI.

Title

The preparation and properties of a new glyceraldehyde-3-phosphate dehydrogenase from photosynthetic tissues.

Journal

J Biol Chem 217:361-71 (1955)

Other DBs

ExplorEnz - The Enzyme Database:

1.2.1.13

IUBMB Enzyme Nomenclature:

1.2.1.13

ExPASy - ENZYME nomenclature database:

1.2.1.13

BRENDA, the Enzyme Database:

1.2.1.13

CAS:	37250-87-6

DBGET integrated database retrieval system