Entry
Name
aldehyde dehydrogenase (NADP+);
NADP-acetaldehyde dehydrogenase;
NADP-dependent aldehyde dehydrogenase;
aldehyde dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
aldehyde:NADP+ oxidoreductase
Reaction(IUBMB)
an aldehyde + NADP+ + H2O = a carboxylate + NADPH + H+ [RN:
R00634 ]
Reaction(KEGG)
Substrate
Product
History
EC 1.2.1.4 created 1961
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K14519 NADP-dependent aldehyde dehydrogenase
Genes
MYW : BVC93_03135 BVC93_12320 BVC93_32530
NAH : F5544_03970 F5544_18980
RHA : RHA1_ro02898 RHA1_ro08151
ROA : Pd630_LPD01864 Pd630_LPD07647
RKO : JWS14_15360 JWS14_29370
SVL : Strvi_6068 Strvi_6961
SRC : M271_36920 M271_42100
SALS : SLNWT_3889 SLNWT_5169
SAMB : SAM23877_1946(aldH)
SPRI : SPRI_5639 SPRI_6598
SCZ : ABE83_05080 ABE83_28580
SLE : sle_52630(sle_52630)
SPHV : F9278_09390 F9278_41905
SBAT : G4Z16_27200 G4Z16_31395
SVD : CP969_10400 CP969_21185
SMAO : CAG99_10430 CAG99_23505
SXT : KPP03845_102113(aldH)
STSD : HEP87_15065 HEP87_55910
LEIF : HF024_03025 HF024_15475 HF024_15560
MPAL : BO218_08130 BO218_12285
MICS : C1N74_02830 C1N74_14770
MARK : QUC20_02590 QUC20_14930
MRG : SM116_00515 SM116_06865 SM116_15340 SM116_16410 SM116_17005
MPLN : VC184_02550 VC184_15395
FSB : GCM10025867_00480 GCM10025867_45210
AGY : ATC03_04975 ATC03_15645
AMAU : DSM26151_06040 DSM26151_17850(aldH)
AMAV : GCM10025877_10010 GCM10025877_25320
AIL : FLP10_04420 FLP10_15845
PFLU : BWO91_05185 BWO91_15705
LVI : G7068_14510 G7068_14680
LRP : MUN76_04920 MUN76_10700
HEA : HL652_16540 HL652_20135
NEX : NE857_16965 NE857_33615
SPIQ : OHA34_05085 OHA34_26290
ACTQ : OG417_24665 OG417_28700
AOI : AORI_3623(aldH) AORI_4998(aldH)
AJA : AJAP_14530 AJAP_21020
AACD : LWP59_12210 LWP59_13140 LWP59_13260
AROO : NQK81_04430 NQK81_41980
ATHM : L1857_01275 L1857_22100
AMOG : QRX60_45345 QRX60_45350 QRX60_46660
ACOR : LCL61_04685 LCL61_26600
AMYZ : HUW46_07145 HUW46_07361(aldH)
KUT : JJ691_102100 JJ691_97310
LED : BBK82_01545 BBK82_46985
DROS : Drose_16805 Drose_25845
NHY : JQS43_03115 JQS43_13575
BALA : DSM104299_01704(aldH)
» show all
Taxonomy
Reference
1
Authors
Adachi O, Matsushita K, Shinagawa E, Ameyama M.
Title
Crystallization and properties of NADP-dependent aldehyde dehydrogenase from Gluconobacter melanogenus.
Journal
Agric Biol Chem 44:155-164 (1980)
Reference
2
Authors
Jakoby WB.
Title
Aldehyde dehydrogenases.
Journal
In: Boyer PD, Lardy H, Myrback K (eds). The Enzymes. 2nd ed. Vol. 7. New York: Academic Press; 1963. p. 203-221.
Reference
3
Authors
Nakayama T.
Title
Acetic acid bacteria. II. Intracellular distribution of enzymes related to acetic acid fermentation, and some properties of a highly purified triphosphopyridine nucleotide (TPN)-dependent aldehyde dehydrogenase.
Journal
J Biochem (Tokyo) 48:812-830 (1960)
Reference
Authors
SEEGMILLER JE.
Title
Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast.
Journal
J Biol Chem 201:629-37 (1953)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.4
ExPASy - ENZYME nomenclature database: 1.2.1.4
BRENDA, the Enzyme Database: 1.2.1.4