KEGG   ENZYME: 1.2.1.4
Entry
EC 1.2.1.4                  Enzyme                                 

Name
aldehyde dehydrogenase (NADP+);
NADP-acetaldehyde dehydrogenase;
NADP-dependent aldehyde dehydrogenase;
aldehyde dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
aldehyde:NADP+ oxidoreductase
Reaction(IUBMB)
an aldehyde + NADP+ + H2O = a carboxylate + NADPH + H+ [RN:R00634]
Reaction(KEGG)
R00634 > R00711 R05099
Substrate
aldehyde [CPD:C00071];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
carboxylate [CPD:C00060];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.2.1.4 created 1961
Pathway
ec00930  Caprolactam degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14519  NADP-dependent aldehyde dehydrogenase
Genes
POL: Bpro_2298
AAV: Aave_0115
PDE: Pden_3264
HBA: Hbal_2501
MGO: AFA91_18385
MMAG: MMAD_17910
MTY: MTOK_16350
MMAT: MMAGJ_18140
CSUR: N24_0341(aldH)
NBR: O3I_014410
NOZ: DMB37_12025
NAH: F5544_03970 F5544_18980
NIE: KV110_32105
RHA: RHA1_ro02898 RHA1_ro08151
REB: XU06_29340
ROP: ROP_04960 ROP_33690
ROA: Pd630_LPD01864 Pd630_LPD07647
RPY: Y013_12795
RKO: JWS14_15360 JWS14_29370
GPO: GPOL_c08310
GAM: GII34_11230
SCO: SCO1871(SCI39.18c)
SALB: XNR_4954
SMA: SAVERM_6389
SGR: SGR_5625
SGB: WQO_07195
SCB: SCAB_70651
SSX: SACTE_1304
SVL: Strvi_6068 Strvi_6961
SHY: SHJG_3333
SHO: SHJGH_3098
SRC: M271_36920 M271_42100
SSOI: I1A49_12290
SCT: SCAT_1069(aldH)
SCY: SCATT_10640
SFA: Sfla_4940
SBH: SBI_08125
SVE: SVEN_1516
SDV: BN159_6637
SALS: SLNWT_3889 SLNWT_5169
STRP: F750_1741
SFI: SFUL_1445
SCI: B446_09735
SALU: DC74_2375
SALL: SAZ_13230
SLV: SLIV_28360
SGU: SGLAU_08360
SVT: SVTN_09040
STRE: GZL_06632
SCW: TU94_07955
SXI: SXIM_08460
STRM: M444_09735
STRC: AA958_05410
SAMB: SAM23877_1946(aldH)
SPRI: SPRI_5639 SPRI_6598
SCZ: ABE83_05080 ABE83_28580
SCX: AS200_33840
SRW: TUE45_02355(aldH)
STRF: ASR50_09120
SLE: sle_52630(sle_52630)
SRN: A4G23_01098(aldH)
SPAV: Spa2297_07475
STRT: A8713_06920
SGS: AVL59_36200
STSI: A4E84_09445
SKY: D0C37_26780
SALW: CP975_07930
SGM: GCM10017557_63870
SCAD: DN051_29150
SLS: SLINC_2143
SNR: SNOUR_30860
SPLU: LK06_006345
STRD: NI25_29855
SSIA: A7J05_27570
SPUN: BFF78_31920
SALF: SMD44_02024(aldH)
SLX: SLAV_28055(aldH)
SFK: KY5_1790c
SNZ: DC008_07595
SGE: DWG14_06529(aldH)
SDX: C4B68_30950
SGD: ELQ87_30185
SCYA: EJ357_10760
SAST: CD934_26295
SNQ: CP978_09035
SKA: CP970_33710
SGZ: C0216_22605
SVN: CP980_25430
SNK: CP967_26925
SHAW: CEB94_09900
SFIC: EIZ62_25730
SGAL: CP966_08010
SPAD: DVK44_05385
SFY: GFH48_30745
SAQU: EJC51_12510
SGF: HEP81_07415
SCAV: CVT27_06070
SSEO: D0Z67_06320
SBY: H7H31_27955
SRIM: CP984_31595
SSUB: CP968_25250
SPHV: F9278_09390 F9278_41905
SCIN: CP977_08425
SFUG: CNQ36_08105
SPAC: B1H29_28125
SCHA: CP983_33330
SGX: H4W23_09490
SCOE: CP976_10630
SBAT: G4Z16_27200 G4Z16_31395
SSPB: CP982_11050
SNF: JYK04_02543(aldH)
SPLA: CP981_09390
SBRO: GQF42_12225
STUI: GCM10017668_14690
SATA: C5746_10310
SCHF: IPT68_08685
SHUN: DWB77_05847(aldH)
SHAR: HUT13_04790
SCYG: S1361_10270(aldH)
SFEU: IM697_12885
SLIA: HA039_26585
SDW: K7C20_08905
SVD: CP969_10400 CP969_21185
KAB: B7C62_06205
LEIF: HF024_03025 HF024_15475 HF024_15560
LSE: F1C12_02900
CMI: CMM_0812
CMS: CMS0069
CMC: CMN_00768
CMH: VO01_12315
CZH: H9X71_03675
MCW: A8L33_01720
MPAL: BO218_08130 BO218_12285
MPRT: ET475_03200
MCHN: HCR76_14865
AGY: ATC03_04975 ATC03_15645
LEB: G7066_05385
LDN: H9L06_03900
LVI: G7068_14510 G7068_14680
HEA: HL652_16540 HL652_20135
GLN: F1C58_00235
ART: Arth_3335
ARR: ARUE_c34530(aldH)
ARM: ART_2596
ARE: AL755_00525
AAQ: AOC05_16125
ARW: MB46_17645
ARZ: AUT26_15885
ARI: UM93_13775
AAU: AAur_3317(aldH)
PUE: FV140_17450
ACH: Achl_3135
APN: Asphe3_32640
PSUL: AU252_14625
RSA: RSal33209_1814
BCV: Bcav_0786
LMOI: VV02_11040
HALT: IM660_17765
NCA: Noca_0086
MUZ: H4N58_00735
KFL: Kfla_6632
KQI: F1D05_17890
TFU: Tfu_1706
NDA: Ndas_5346
NAL: B005_1809
NFE: HUT17_01055
SRO: Sros_1486
NCX: Nocox_10180(aldH)
TBI: Tbis_1086 Tbis_1743
FRE: Franean1_4676
GOB: Gobs_2395
BSD: BLASA_1682(aldH)
SEN: SACE_1997 SACE_2783
SACG: FDZ84_03090
AMD: AMED_5971
AMN: RAM_30625
AMM: AMES_5887
AMZ: B737_5887
AOI: AORI_3623(aldH) AORI_4998(aldH)
AJA: AJAP_14530 AJAP_21020
AMQ: AMETH_6878
AORI: SD37_24610
PHH: AFB00_20980
AMI: Amir_1484 Amir_4721
KAL: KALB_6874
KPHY: AOZ06_14455
LED: BBK82_01545 BBK82_46985
AHM: TL08_12515
ACTI: UA75_13535
ACAD: UA74_13450
AMS: AMIS_59920
AIH: Aiant_90370
ATL: Athai_51790
ASER: Asera_23020
PRY: Prubr_70620
CAI: Caci_7805
SNA: Snas_4113
NAV: JQS30_15595
CWO: Cwoe_3952
RBA: RB1887
 » show all
Reference
1
  Authors
Adachi, O., Matsushita, K., Shinagawa, E. and Ameyama, M.
  Title
Crystallization and properties of NADP-dependent aldehyde dehydrogenase from Gluconobacter melanogenus.
  Journal
Agric Biol Chem 44:155-164 (1980)
Reference
2
  Authors
Jakoby, W.B.
  Title
Aldehyde dehydrogenases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 203-221.
Reference
3
  Authors
Nakayama, T.
  Title
Acetic acid bacteria. II. Intracellular distribution of enzymes related to acetic acid fermentation, and some properties of a highly purified triphosphopyridine nucleotide (TPN)-dependent aldehyde dehydrogenase.
  Journal
J Biochem (Tokyo) 48:812-830 (1960)
Reference
4  [PMID:13061400]
  Authors
SEEGMILLER JE.
  Title
Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast.
  Journal
J Biol Chem 201:629-37 (1953)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.4
IUBMB Enzyme Nomenclature: 1.2.1.4
ExPASy - ENZYME nomenclature database: 1.2.1.4
BRENDA, the Enzyme Database: 1.2.1.4
CAS: 9028-87-9

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   GenBank (359)   
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