| Entry |
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| Name |
hexadecanal dehydrogenase (acylating);
fatty acyl-CoA reductase
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| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
hexadecanal:NAD+ oxidoreductase (CoA-acylating)
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| Reaction(IUBMB) |
hexadecanal + CoA + NAD+ = hexadecanoyl-CoA + NADH + H+ [RN: R01277]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Also acts, more slowly, on octadecanoyl-CoA.
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| History |
EC 1.2.1.42 created 1978
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| Reference |
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| Authors |
Johnson RC, Gilbertson JR. |
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| Title |
Isolation, characterization, and partial purification of a fatty acyl coenzyme A reductase from bovine cardiac muscle. |
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| Journal |
J Biol Chem 247:6991-8 (1972) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.2.1.42 |
| ExPASy - ENZYME nomenclature database: | 1.2.1.42 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.2.1.42 |
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