KEGG   ENZYME: 1.2.1.47Help
Entry
EC 1.2.1.47                 Enzyme                                 

Name
4-trimethylammoniobutyraldehyde dehydrogenase;
4-trimethylaminobutyraldehyde dehydrogenase;
4-N-trimethylaminobutyraldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-trimethylammoniobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-trimethylammoniobutanal + NAD+ + H2O = 4-trimethylammoniobutanoate + NADH + 2 H+ [RN:R03283]
Reaction(KEGG)
Substrate
4-trimethylammoniobutanal [CPD:C01149];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-trimethylammoniobutanoate [CPD:C01181];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.2.1.47 created 1983
Pathway
ec00310  Lysine degradation
ec01100  Metabolic pathways
Orthology
K00149  aldehyde dehydrogenase family 9 member A1
Genes
HSA: 223(ALDH9A1)
PTR: 457478(ALDH9A1)
PPS: 100993750(ALDH9A1)
GGO: 101154127(ALDH9A1)
PON: 100173126(ALDH9A1)
NLE: 100594899(ALDH9A1)
MCC: 695383(ALDH9A1)
MCF: 102139794(ALDH9A1)
CSAB: 103230676(ALDH9A1)
RRO: 104670179(ALDH9A1)
RBB: 108538368(ALDH9A1)
CJC: 100385191(ALDH9A1)
SBQ: 101041228(ALDH9A1)
MMU: 56752(Aldh9a1)
MCAL: 110291593(Aldh9a1)
MPAH: 110321543(Aldh9a1)
RNO: 64040(Aldh9a1)
MUN: 110551797(Aldh9a1)
CGE: 100758951(Aldh9a1)
NGI: 103746122(Aldh9a1)
HGL: 101717741(Aldh9a1)
CCAN: 109693621(Aldh9a1)
OCU: 100354540(ALDH9A1)
TUP: 102490252(ALDH9A1)
CFA: 478991(ALDH9A1)
VVP: 112914316(ALDH9A1)
AML: 100478544(ALDH9A1)
UMR: 103658223(ALDH9A1)
UAH: 113268692(ALDH9A1)
ORO: 101369155(ALDH9A1)
FCA: 101080506(ALDH9A1)
PTG: 102951347(ALDH9A1)
PPAD: 109276686 109276687(ALDH9A1)
AJU: 106965587(ALDH9A1)
BTA: 537539(ALDH9A1)
BOM: 102268762(ALDH9A1)
BIU: 109577815(ALDH9A1)
BBUB: 102402462(ALDH9A1)
CHX: 102174989(ALDH9A1)
OAS: 101109411(ALDH9A1)
SSC: 100153809(ALDH9A1)
CFR: 102516577(ALDH9A1)
CDK: 105092715(ALDH9A1)
BACU: 103018805(ALDH9A1)
LVE: 103080404(ALDH9A1)
OOR: 101290165(ALDH9A1)
DLE: 111169235(ALDH9A1)
PCAD: 102978670(ALDH9A1)
ECB: 100060577(ALDH9A1)
EPZ: 103547344(ALDH9A1)
EAI: 106831128(ALDH9A1)
MYB: 102242624(ALDH9A1) 106723970
MYD: 102768395(ALDH9A1)
MNA: 107537941(ALDH9A1)
HAI: 109385009(ALDH9A1)
DRO: 112298789(ALDH9A1)
PALE: 102890956(ALDH9A1)
RAY: 107512731(ALDH9A1)
MJV: 108402717(ALDH9A1)
LAV: 100654610(ALDH9A1)
TMU: 101357831
MDO: 100016819(ALDH9A1)
SHR: 100932529(ALDH9A1)
PCW: 110202730(ALDH9A1)
OAA: 100076925(ALDH9A1)
GGA: 424405(ALDH9A1)
MGP: 100546048(ALDH9A1)
CJO: 107317241(ALDH9A1)
NMEL: 110402617(ALDH9A1)
APLA: 101799816(ALDH9A1)
ACYG: 106047784(ALDH9A1)
TGU: 100225645(ALDH9A1)
LSR: 110478928(ALDH9A1)
SCAN: 103823370(ALDH9A1)
GFR: 102035153(ALDH9A1)
FAB: 101805672(ALDH9A1)
PHI: 102099646(ALDH9A1)
PMAJ: 107208324(ALDH9A1)
CCAE: 111932630(ALDH9A1)
CCW: 104695470(ALDH9A1)
ETL: 114063532(ALDH9A1)
FPG: 101920083(ALDH9A1)
FCH: 102058365(ALDH9A1)
CLV: 102087254(ALDH9A1)
EGZ: 104132054(ALDH9A1)
NNI: 104010385(ALDH9A1)
ACUN: 113482682(ALDH9A1)
PADL: 103914112(ALDH9A1)
AAM: 106494013(ALDH9A1)
ASN: 102375346(ALDH9A1)
AMJ: 102576324(ALDH9A1)
PSS: 102457679(ALDH9A1)
CMY: 102933952(ALDH9A1)
CPIC: 101934924(ALDH9A1)
ACS: 100555336(aldh9a1)
PVT: 110089732(ALDH9A1)
PBI: 103056986(ALDH9A1)
PMUR: 107301157(ALDH9A1)
TSR: 106553466(ALDH9A1)
PMUA: 114598470(ALDH9A1)
GJA: 107106980 107118664(ALDH9A1)
XLA: 379229(aldh9a1.S)
XTR: 448752(aldh9a1)
NPR: 108798628(ALDH9A1)
DRE: 100005587(aldh9a1a.1) 399481(aldh9a1b)
CCAR: 109091657
IPU: 100304680(aldh9a1) 108267615
PHYP: 113534319(aldh9a1) 113540404
AMEX: 103023076(aldh9a1)
OLA: 100049493(aldh9a1) 101155544
PRET: 103463999(aldh9a1) 103479006
CVG: 107083604 107091527(aldh9a1)
KMR: 108238305 108246250(aldh9a1)
ALIM: 106527178 106529303(aldh9a1)
AOCE: 111576143(aldh9a1) 111587224
POV: 109625726(aldh9a1) 109643918
SLAL: 111662617(aldh9a1) 111670534
BPEC: 110154734(aldh9a1) 110173534
SASA: 100195073(aldh9a1)
ELS: 105021913 105030670(aldh9a1)
PKI: 111834917(aldh9a1)
LCM: 102350441(ALDH9A1)
CMK: 103180031(aldh9a1)
RTP: 109934140
CIN: 100175707
APLC: 110988120
SKO: 100373270
CSCU: 111642601
PTEP: 107456012
CEL: CELE_F42G9.5(alh-11) CELE_Y69F12A.2(alh-12)
CBR: CBG09190(Cbr-alh-12) CBG15207(Cbr-alh-11)
BMY: Bm1_28330
PCAN: 112564937
MYI: 110463364
OBI: 106875644
LAK: 106174689
EPA: 110231719
ADF: 107327307
AMIL: 114969260
PDAM: 113684365
SPIS: 111332314
DGT: 114518896
HMG: 100205388
 » show all
Taxonomy
Reference
1  [PMID:6770910]
  Authors
Rebouche CJ, Engel AG.
  Title
Tissue distribution of carnitine biosynthetic enzymes in man.
  Journal
Biochim Biophys Acta 630:22-9 (1980)
DOI:10.1016/0304-4165(80)90133-6
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.47
IUBMB Enzyme Nomenclature: 1.2.1.47
ExPASy - ENZYME nomenclature database: 1.2.1.47
BRENDA, the Enzyme Database: 1.2.1.47
CAS: 73361-01-0

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