KEGG   ENZYME: 1.2.1.47
Entry
EC 1.2.1.47                 Enzyme                                 
Name
4-trimethylammoniobutyraldehyde dehydrogenase;
4-trimethylaminobutyraldehyde dehydrogenase;
4-N-trimethylaminobutyraldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
4-trimethylammoniobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-trimethylammoniobutanal + NAD+ + H2O = 4-trimethylammoniobutanoate + NADH + 2 H+ [RN:R03283]
Reaction(KEGG)
R03283
Substrate
4-trimethylammoniobutanal [CPD:C01149];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-trimethylammoniobutanoate [CPD:C01181];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.2.1.47 created 1983
Pathway
ec00310  Lysine degradation
ec01100  Metabolic pathways
Orthology
K00149  aldehyde dehydrogenase family 9 member A1
Genes
HSA223(ALDH9A1)
PTR457478(ALDH9A1)
PPS100993750(ALDH9A1)
GGO101154127(ALDH9A1)
PON100173126(ALDH9A1)
NLE100594899(ALDH9A1)
MCC695383(ALDH9A1)
MCF102139794(ALDH9A1)
MTHB126941794
CSAB103230676(ALDH9A1)
CATY105598281(ALDH9A1)
PANU101016128 116268495(ALDH9A1)
TGE112608179(ALDH9A1)
RRO104670179(ALDH9A1)
RBB108538368(ALDH9A1)
TFN117074300(ALDH9A1)
PTEH111539280(ALDH9A1)
CJC100385191(ALDH9A1)
SBQ101041228(ALDH9A1)
CSYR103273649(ALDH9A1)
MMUR105860496(ALDH9A1)
LCAT123634927(ALDH9A1)
OGA100940587(ALDH9A1)
MMU56752(Aldh9a1)
MCAL110291593(Aldh9a1)
MPAH110321543(Aldh9a1)
RNO64040(Aldh9a1)
MCOC116103062(Aldh9a1)
MUN110551797(Aldh9a1)
CGE100758951(Aldh9a1)
MAUA101838319(Aldh9a1)
PLEU114689914(Aldh9a1) 114694603 114695271
MORG121455143(Aldh9a1)
MFOT126511267
AAMP119827527(Aldh9a1)
NGI103746122(Aldh9a1)
HGL101717741(Aldh9a1)
CPOC100732288(Aldh9a1)
CCAN109693621(Aldh9a1)
DORD105989613(Aldh9a1)
DSP122106062(Aldh9a1)
NCAR124962313
OCU100354540
OPI101524250(ALDH9A1)
TUP102490252(ALDH9A1)
GVR103595312(ALDH9A1)
CFA478991(ALDH9A1)
CLUD112643080(ALDH9A1)
VVP112914316(ALDH9A1)
VLG121471727(ALDH9A1)
AML100478544(ALDH9A1)
UMR103658223(ALDH9A1)
UAH113268692(ALDH9A1)
UAR123800139(ALDH9A1)
ELK111151106
LLV125086052
MPUF101670514(ALDH9A1)
ORO101369155(ALDH9A1)
EJU114210485(ALDH9A1)
ZCA113933528(ALDH9A1)
MLX118014052(ALDH9A1)
NSU110588170(ALDH9A1)
LWW102729065(ALDH9A1)
FCA101080506(ALDH9A1)
PYU121020938(ALDH9A1)
PBG122476213(ALDH9A1)
LRUF124509924
PTG102951347(ALDH9A1)
PPAD109276686 109276687(ALDH9A1)
AJU106965587(ALDH9A1)
HHV120223223(ALDH9A1)
BTA537539(ALDH9A1)
BOM102268762(ALDH9A1)
BIU109577815(ALDH9A1)
BBUB102402462(ALDH9A1)
BBIS104997306(ALDH9A1)
CHX102174989(ALDH9A1)
OAS101109411(ALDH9A1)
ODA120855495(ALDH9A1)
CCAD122429812(ALDH9A1)
SSC100153809(ALDH9A1)
CFR102516577(ALDH9A1)
CBAI105068048(ALDH9A1)
CDK105092715(ALDH9A1)
VPC102541141(ALDH9A1)
BACU103018805(ALDH9A1)
LVE103080404(ALDH9A1)
OOR101290165(ALDH9A1)
DLE111169235(ALDH9A1)
PCAD102978670(ALDH9A1)
PSIU116754267(ALDH9A1)
ECB100060577(ALDH9A1)
EPZ103547344(ALDH9A1)
EAI106831128(ALDH9A1)
MYB102242624(ALDH9A1)
MYD102768395(ALDH9A1)
MMYO118672934(ALDH9A1)
MLF102428549(ALDH9A1)
MNA107537941(ALDH9A1)
PKL118721740(ALDH9A1)
HAI109385009(ALDH9A1)
DRO112298789(ALDH9A1)
SHON118979265(ALDH9A1)
AJM119065427(ALDH9A1)
PDIC114512161(ALDH9A1)
PHAS123818508(ALDH9A1)
MMF118637299(ALDH9A1)
RFQ117014975(ALDH9A1)
PALE102890956(ALDH9A1)
PGIG120617722(ALDH9A1)
PVP105301520(ALDH9A1)
RAY107512731(ALDH9A1)
MJV108402717(ALDH9A1)
TOD119241361(ALDH9A1)
SARA101548414(ALDH9A1)
LAV100654610(ALDH9A1)
TMU101357831
ETF101660372(ALDH9A1)
DNM101425023(ALDH9A1)
MDO100016819(ALDH9A1)
GAS123245877(ALDH9A1)
SHR100932529(ALDH9A1)
PCW110202730(ALDH9A1)
OAA100076925(ALDH9A1)
GGA424405(ALDH9A1)
PCOC116230466(ALDH9A1)
MGP100546048(ALDH9A1)
CJO107317241(ALDH9A1)
NMEL110402617(ALDH9A1)
APLA101799816(ALDH9A1)
ACYG106047784(ALDH9A1)
AFUL116492081(ALDH9A1)
TGU100225645(ALDH9A1)
LSR110478928(ALDH9A1)
SCAN103823370(ALDH9A1)
PMOA120512203(ALDH9A1)
OTC121344258(ALDH9A1)
PRUF121359756(ALDH9A1)
GFR102035153(ALDH9A1)
FAB101805672(ALDH9A1)
PHI102099646(ALDH9A1)
PMAJ107208324(ALDH9A1)
CCAE111932630(ALDH9A1)
CCW104695470(ALDH9A1)
CBRC103612514(ALDH9A1)
ETL114063532(ALDH9A1)
ZAB102074492(ALDH9A1)
ACHL103806597(ALDH9A1)
FPG101920083(ALDH9A1)
FCH102058365(ALDH9A1)
CLV102087254(ALDH9A1)
EGZ104132054(ALDH9A1)
NNI104010385(ALDH9A1)
PLET104627477(ALDH9A1)
PCRI104033069(ALDH9A1)
PCAO104051486(ALDH9A1)
ACUN113482682(ALDH9A1)
TALA104368445(ALDH9A1)
PADL103914112(ALDH9A1)
AFOR103893982(ALDH9A1)
ACHC115348812(ALDH9A1)
HALD104316564(ALDH9A1)
HLE104840644(ALDH9A1)
AGEN126042168
GCL127018915
CCRI104163762(ALDH9A1)
CSTI104560212(ALDH9A1)
EHS104504155(ALDH9A1)
CMAC104474432(ALDH9A1)
MUI104543235(ALDH9A1)
FGA104078039(ALDH9A1)
GSTE104259204(ALDH9A1)
LDI104341112(ALDH9A1)
MNB103778612(ALDH9A1)
OHA104333710(ALDH9A1)
NNT104402409(ALDH9A1)
DPUB104301538(ALDH9A1)
PGUU104470352(ALDH9A1)
ACAR104528703(ALDH9A1)
CPEA104392904(ALDH9A1)
AVIT104270405(ALDH9A1)
CVF104293413(ALDH9A1)
CUCA104058350(ALDH9A1)
TEO104375266(ALDH9A1)
BRHI104496263(ALDH9A1)
AAM106494013(ALDH9A1)
AROW112975020(ALDH9A1)
NPD112950395(ALDH9A1)
TGT104578432(ALDH9A1)
DNE112983696(ALDH9A1)
SCAM104142675(ALDH9A1)
ASN102375346(ALDH9A1)
AMJ102576324(ALDH9A1)
CPOO109307135(ALDH9A1)
GGN109305349(ALDH9A1)
PSS102457679(ALDH9A1)
CMY102933952(ALDH9A1)
CPIC101934924(ALDH9A1)
TST117881335(ALDH9A1)
CABI116839902(ALDH9A1)
MRV120370350(ALDH9A1)
ACS100555336(aldh9a1)
PVT110089732(ALDH9A1)
SUND121929230
PBI103056986(ALDH9A1)
PMUR107301157(ALDH9A1)
CTIG120300230(ALDH9A1)
TSR106553466(ALDH9A1)
PGUT117661250(ALDH9A1)
VKO123028003(ALDH9A1)
PMUA114598470(ALDH9A1)
ZVI118078513(ALDH9A1)
GJA107106980 107118664(ALDH9A1)
STOW125433300(ALDH9A1)
XLA379229(aldh9a1.S)
XTR448752(aldh9a1)
NPR108798628(ALDH9A1)
RTEM120945531(ALDH9A1)
BBUF120990494(ALDH9A1)
BGAR122938711(ALDH9A1)
DRE100005587(aldh9a1a.1) 100006238(aldh9a1a.2) 399481(aldh9a1b)
SRX107719265(aldh9a1) 107731138 107745793
SANH107668102 107681718 107695268
SGH107549103(aldh9a1) 107585917 107593789
CAUA113046048 113069931 113107227
PPRM120471402(aldh9a1b) 120482966 120483018(aldh9a1a.1)
MAMB125250605(aldh9a1b) 125279352(aldh9a1a.1)
IPU100304680(aldh9a1a.1) 108267615(aldh9a1b)
PHYP113534319(aldh9a1) 113540404
SMEO124387435(aldh9a1b) 124400405(aldh9a1a.1)
TFD113649154(aldh9a1b) 113655774(aldh9a1a.1)
AMEX103023076(aldh9a1)
EEE113570097 113581120
TRU101062653 101068320
TNGGSTEN00001095G001 GSTEN00012851G001 GSTEN00013360G001
LCO104921743 104935074
NCC104949684 104957497(aldh9a1)
CGOB115006566(aldh9a1) 115022391
ELY117254436 117254503 117272275(aldh9a1b)
EFO125895315 125895316 125902067(aldh9a1b)
PLEP121941337 121951599(aldh9a1b)
SLUC116039685 116045793(aldh9a1b)
ECRA117953527 117953994(aldh9a1b)
ESP116696438 116699766
PFLV114564803 114567870
GAT120815650(aldh9a1b) 120823514 120823517
PPUG119209085(aldh9a1b) 119216616(aldh9a1a.1)
MSAM119901224 119902372(aldh9a1b) 119915248
CUD121512793(aldh9a1a.1) 121520033(aldh9a1b)
ALAT119011614(aldh9a1b) 119029163(aldh9a1a.1)
MZE101480450 101486789 106676834
ONL100703463 100707441 102082725 109194280 109196929
OAU116331995(aldh9a1b) 116334433(aldh9a1a.1) 116334435 116334439
OLA100049493(aldh9a1) 101155544
OML112147259(aldh9a1b) 112150670(aldh9a1a.1)
XMA102221886 102234230
XCO114145904 114151030
XHE116721132 116726383
PRET103463999(aldh9a1) 103479006
PFOR103139831(aldh9a1) 103140077
PLAI106936229(aldh9a1) 106954306
PMEI106928206(aldh9a1) 106930841
GAF122838345(aldh9a1a.1) 122841585(aldh9a1b)
CVG107083604 107091527(aldh9a1)
CTUL119776054(aldh9a1b) 119787723(aldh9a1a.1)
GMU124869680(aldh9a1b) 124873311(aldh9a1a.1)
NFU107384405 107387362
KMR108238305(aldh9a1b) 108246250(aldh9a1a.1)
ALIM106527178 106529303(aldh9a1)
NWH119415014(aldh9a1b) 119430681
AOCE111576143(aldh9a1) 111587224
MCEP125009774(aldh9a1a.1) 125010532(aldh9a1b)
CSEM103395824 103398401
POV109625726(aldh9a1) 109643918
SSEN122774348(aldh9a1b) 122780333(aldh9a1a.1)
HHIP117759770(aldh9a1a.1) 117778156(aldh9a1b)
HSP118117824(aldh9a1b) 118121327(aldh9a1a.1)
LCF108878969(aldh9a1a.1) 108883809(aldh9a1b)
SDU111228945 111231960
SLAL111662617(aldh9a1) 111670534
XGL120790502(aldh9a1a.1) 120799386(aldh9a1b)
HCQ109516943 109521205
BPEC110154734(aldh9a1) 110173534
BSPL114844019(aldh9a1b) 114853357(aldh9a1a.1)
SASA100195073(aldh9a1)
STRU115157269 115158685(aldh9a1)
OTW112251350(aldh9a1a.1) 112260713(aldh9a1b)
OMY110524695(aldh9a1a.1)
OGO123996681(aldh9a1a.1) 124009501(aldh9a1b)
ONE115108629(aldh9a1) 115114631
SALP111956650 111975454
SNH120054983(aldh9a1a.1) 120056049(aldh9a1b)
CCLU121533848 121535589(aldh9a1b)
ELS105021913 105030670(aldh9a1)
SFM108935320 108935571
PKI111834917(aldh9a1)
AANG118225547(aldh9a1a.1)
LOC102690012(aldh9a1)
PSPA121326944
ARUT117414144
PSEX120515228(aldh9a1a.1)
LCM102350441(ALDH9A1)
CMK103180031(aldh9a1a.1)
RTP109934140
BFO118422089
BBEL109466188
CIN100175707
SCLV120327504
SPU115918585 580956 583864
APLC110988120
AJC117106271
SKO100373270
SGRE126364944
DPXDAPPUDRAFT_302871
DMK116918997
DPZ124344155
PVM113817093 113817275
PJA122249287
PCHN125024670
HAME121858672
PCLA123767126
PTRU123515200
HAZT108664939
LSM121116498
PPOI119110450 119110456
ISCIscW_ISCW008939
DSV119442151
RSAN119387793 119397029
CSCU111642601
PTEP107456012
SDM118198540
CELCELE_F42G9.5(alh-11) CELE_Y69F12A.2(alh-12)
CBRCBG_09190(Cbr-alh-12) CBG_15207(Cbr-alh-11)
BMYBM_BM4035(Bma-alh-11)
LOALOAG_02927
NAINECAME_04500 NECAME_09317
HROHELRODRAFT_112795
LGILOTGIDRAFT_139335
PCAN112564937
BGT106072008
GAE121381337
HRF124146729
HRJ124264878
CRG105326193
MYI110463364
PMAX117344030
MMER123531280
OBI106875644
OSN115225913
LAK106174689
SMMSmp_210440
SHXMS3_00009869(ALDH9A1_3)
OVIT265_08551
NVE5497838 5505711
EPA110231719
ATEN116300320
ADF107327307
AMIL114969260
PDAM113684365
SPIS111332314
DGT114518896
XEN124439653
HMG100205388
TADTRIADDRAFT_21102
 » show all
Reference
1  [PMID:6770910]
  Authors
Rebouche CJ, Engel AG.
  Title
Tissue distribution of carnitine biosynthetic enzymes in man.
  Journal
Biochim Biophys Acta 630:22-9 (1980)
DOI:10.1016/0304-4165(80)90133-6
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.47
IUBMB Enzyme Nomenclature: 1.2.1.47
ExPASy - ENZYME nomenclature database: 1.2.1.47
BRENDA, the Enzyme Database: 1.2.1.47
CAS: 73361-01-0

DBGET integrated database retrieval system