KEGG   ENZYME: 1.2.1.54
Entry
EC 1.2.1.54                 Enzyme                                 

Name
gamma-guanidinobutyraldehyde dehydrogenase;
alpha-guanidinobutyraldehyde dehydrogenase;
4-guanidinobutyraldehyde dehydrogenase;
GBAL dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
4-guanidinobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-guanidinobutanal + NAD+ + H2O = 4-guanidinobutanoate + NADH + 2 H+ [RN:R03177]
Reaction(KEGG)
R03177
Substrate
4-guanidinobutanal [CPD:C02647];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-guanidinobutanoate [CPD:C01035];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the degradation of arginine in Pseudomonas putida (cf. EC 1.2.1.19 aminobutyraldehyde dehydrogenase).
History
EC 1.2.1.54 created 1989
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K12254  4-guanidinobutyraldehyde dehydrogenase / NAD-dependent aldehyde dehydrogenase
Genes
LVE: 103091159
SLQ: M495_12010
XAL: XALC_2105
XSA: SB85_04725
XTN: FD63_11895
XHY: FZ025_01015
SML: Smlt1571(aldH)
SMT: Smal_1330
BUJ: BurJV3_1321
SMZ: SMD_1402(aldH)
PSUW: WQ53_02590
PSD: DSC_07485
PAE: PA5312
PAEV: N297_5492
PAEI: N296_5492
PAU: PA14_70140(aldH)
PNC: NCGM2_6076(aldH)
PAEB: NCGM1900_6154(aldH)
PAEP: PA1S_28715
PAEM: U769_29220
PAEL: T223_29175
PAEG: AI22_05275
PAEC: M802_5490
PAEO: M801_5357
PMY: Pmen_0237
PMK: MDS_0290
PPSE: BN5_0159
PCQ: PcP3B5_54750(puuC_3) PcP3B5_60480(puuC_4)
PPU: PP_5278(kauB)
PPF: Pput_5188
PPI: YSA_04677
PPX: T1E_2789
PPUH: B479_26140
PPUT: L483_31550
PPUN: PP4_53430
PSB: Psyr_0227
PSYR: N018_00480
PVD: CFBP1590_0205(puuC)
PFL: PFL_6046
PPRC: PFLCHA0_c24080(puuC1) PFLCHA0_c60050(puuC4)
PFS: PFLU_5976(aldH)
PFB: VO64_2867
PEN: PSEEN5424(aldH)
PSA: PST_0046
PSTT: CH92_21230
PKC: PKB_5073(puuc3) PKB_5650(puuc5)
PSEC: CCOS191_5174(puuC3)
PANR: A7J50_5711
PSET: THL1_5607
AVN: Avin_48030(aldH)
AVL: AvCA_48030(aldH)
AVD: AvCA6_48030(aldH)
ACX: Achr_37390(aldH)
FBL: Fbal_1146
SAGA: M5M_11425
MICC: AUP74_00575(puuC)
MICT: FIU95_19470(puuC)
HCO: LOKO_02562(puuC)
HBE: BEI_1148
RFO: REIFOR_00600(puuC)
ASA: ASA_4155
AVR: B565_3831
AMED: B224_5460
ASR: WL1483_1298(puuC)
ACAV: VI35_20215
AEL: NCTC12917_04090(puuC)
OCE: GU3_00195
BMK: DM80_3359
PLG: NCTC10937_00050(puuC_1)
HYF: DTO96_100783(puuC)
HYB: Q5W_22305
HPSE: HPF_00630(puuC)
CBAB: SMCB_2218
JAG: GJA_494
LCH: Lcho_1737
TIN: Tint_0186
RGE: RGE_26320(aldH)
PBH: AAW51_2992(puuC)
SIX: BSY16_55
ARA: Arad_8305(dhaL)
MET: M446_3859
RCP: RCAP_rcc02448(aldH2)
RCE: RC1_1452(puuC)
TXI: TH3_10790
SMAL: SMALA_7627
AMN: RAM_31850
AMM: AMES_6118(puuC)
AMZ: B737_6118(puuC)
TBI: Tbis_1741
 » show all
Reference
1
  Authors
Yorifuji, T., Koike, K., Sakurai, T. and Yokoyama, K.
  Title
4-Aminobutyraldehyde and 4-guanidinobutyraldehyde dehydrogenases for arginine degradation in Pseudomonas putida.
  Journal
Agric Biol Chem 50:2009-2016 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.54
IUBMB Enzyme Nomenclature: 1.2.1.54
ExPASy - ENZYME nomenclature database: 1.2.1.54
BRENDA, the Enzyme Database: 1.2.1.54
CAS: 56831-75-5

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