KEGG   ENZYME: 1.2.1.57
Entry
EC 1.2.1.57                 Enzyme                                 
Name
butanal dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
butanal:NAD(P)+ oxidoreductase (CoA-acylating)
Reaction(IUBMB)
butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+ [RN:R01172 R01173]
Reaction(KEGG)
R01172 R01173
Substrate
butanal [CPD:C01412];
CoA [CPD:C00010];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
butanoyl-CoA [CPD:C00136];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts on acetaldehyde, but more slowly.
History
EC 1.2.1.57 created 1992
Pathway
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:3384801]
  Authors
Palosaari NR, Rogers P.
  Title
Purification and properties of the inducible coenzyme A-linked butyraldehyde dehydrogenase from Clostridium acetobutylicum.
  Journal
J Bacteriol 170:2971-6 (1988)
DOI:10.1128/JB.170.7.2971-2976.1988
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.57
IUBMB Enzyme Nomenclature: 1.2.1.57
ExPASy - ENZYME nomenclature database: 1.2.1.57
BRENDA, the Enzyme Database: 1.2.1.57
CAS: 116412-25-0

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