KEGG   ENZYME: 1.2.1.65
Entry
EC 1.2.1.65                 Enzyme                                 
Name
salicylaldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
salicylaldehyde:NAD+ oxidoreductase
Reaction(IUBMB)
salicylaldehyde + NAD+ + H2O = salicylate + NADH + 2 H+ [RN:R02941]
Reaction(KEGG)
R02941
Substrate
salicylaldehyde [CPD:C06202];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
salicylate [CPD:C00805];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the naphthalene degradation pathway in some bacteria.
History
EC 1.2.1.65 created 2000, modified 2011
Pathway
ec00626  Naphthalene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00152  salicylaldehyde dehydrogenase
Genes
PPIND058(nahF)
PSCA458_06710
PSTUUIB01_22640
PBMCL52_14625
PFKPFAS1_28625
RMNTK49_07965
BMKDM80_1446
PARBCJU94_38645
PNAPnap_2482
Reference
1  [PMID:1447127]
  Authors
Eaton RW, Chapman PJ
  Title
Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions.
  Journal
J Bacteriol 174:7542-54 (1992)
DOI:10.1128/JB.174.23.7542-7554.1992
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.65
IUBMB Enzyme Nomenclature: 1.2.1.65
ExPASy - ENZYME nomenclature database: 1.2.1.65
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.65
BRENDA, the Enzyme Database: 1.2.1.65
CAS: 55354-34-2

DBGET integrated database retrieval system