KEGG   ENZYME: 1.2.1.67
Entry
EC 1.2.1.67                 Enzyme                                 
Name
vanillin dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
vanillin:NAD+ oxidoreductase
Reaction(IUBMB)
vanillin + NAD+ + H2O = vanillate + NADH + 2 H+ [RN:R05699]
Reaction(KEGG)
R05699
Substrate
vanillin [CPD:C00755];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
vanillate [CPD:C06672];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.2.1.67 created 2000
Pathway
ec00627  Aminobenzoate degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K21802  vanillin dehydrogenase
Genes
RBDALSL_0890
PPUPP_3357(vdh)
PPFPput_2401
PPWPputW619_2048
PPUTL483_17015 L483_20050
PFVPsefu_4044
PORAPT59_07765
PALDLU682_013230
PSTPSPTO_2943(vdh)
PSBPsyr_2727
PSYRN018_13605
PSPPSPPH_2434(vdh)
PSAVPSA3335_15690
PAMGBKM19_016450
PAVLBKM03_14270
PVDCFBP1590__2835(vdh)
PCABJGS08_12750
PCOFPOR16_12660
PTREI9H09_12405
PSYIMME58_14250
PASTN015_13615
PPRCPFLCHA0_c35180(doxF)
PPROPPC_3627
PFEPSF113_2660(vdh)
PFSPFLU_3299
PTVAA957_00725
PCGAXG94_01495
PVRPverR02_12200
PAZOAYR47_20525
PLULFOB45_07570
PBAPSEBR_a3135
PBCCD58_14290
PSKU771_11775
PCHEY04_17955
PCZPCL1606_25830
PCPJM49_12995
PFZAV641_10365
PSESPSCI_1562
PSEMTO66_18485
PSOSPOS17_3612
PPSLBJP27_22595
POJPtoMrB4_29620
PPSHG5J76_17045
PVKEPZ47_14270
PEZHWQ56_17505
PBZGN234_04240
PASGKSS96_11840
PALVKSS97_15865
PZAHU749_014415
PJUL1P09_10210
PCASLOY40_15215
PKMPZ739_11145
PCUCPSH97_15395
PPAELDL65_24270
AVNAvin_14240(vdh)
AVLAvCA_14240(vdh)
AVDAvCA6_14240(vdh)
ACXAchr_28500(vdh)
HPEGEAO82_07145
ACBA1S_1110
ABYABAYE2629(hcaB)
ABNAB57_1194
ABBABBFA_02402(vdh)
ABABBJAB0715_01300
ABAZP795_11775
ABAUIX87_05295
ABAAIX88_07800
ABALABLAC_19510
ACCBDGL_000390(hcaB)
ANORR32_12620
ALCOTEC02_13365
ACALBUM88_05405
ASEII8T81_13395
ACDAOLE_13750
ACIACIAD1725(hcaB)
AEIAOY20_07250
AHLAHTJS_11625
ASOLBEN76_04870
AUGURS_0069
ADSFPL17_05345
ATNFM020_02775
ATZM5E07_08215
AVIVLF296_12250
SACHK0H61_17515
MPAFR5R33_01765
MBRGPVT68_00675
CYQQ91_0488 Q91_0489
CZACYCME_2136 CYCME_2137
CYYCPC19_10610 CPC19_10615
GAIIMCC3135_15570(vdh_2)
CSACsal_0277
CCAGSR908_06815
HELHELO_3932(vdh)
HAKKO116_00171
HAMHALO0104
HHHCLM76_07215
HOLHORIV_70820 HORIV_70950
HSRHSBAA_65010
HMDCTT34_17540 CTT34_17565
HTTHZS52_05325 HZS52_05355
HCAMI4484_18970
HSXHNO51_19055
HSVHNO53_19315
HTXEKK97_21385
HBHE4T21_12280
HASOB2G49_18350
AXEP40_18880
MPCMar181_2313
MPRIMP3633_1689
MARDIBG28_11195
MFOIJSY38_17870
MRZKDW95_22990
GBIPG2T_11265
SALNSALB1_1072
NBLGJV52_02870
VITADP71_15860
VSTLVJ81_05625
VMSLVJ82_09635
RSORSp0226(vdh)
RSEF504_3665
RPUCDC45_18745
RNCGO999_23140
RSLRPSI07_mp0179(vdh)
RSNRSPO_m00215(vdh)
RSMCMR15_mp10198(vdh)
RSYRSUY_35590(vdh)
RWEKOL96_05165
REUReut_B4869
BMABMAA0630
BMLBMA10229_0836
BMNBMA10247_A1801
BMALDM55_4799
BMAEDM78_3190
BMAQDM76_3753
BMAIDM57_12395
BMAFDM51_4343
BMAZBM44_4789
BMABBM45_4943
BPSBPSS0780
BPMBURPS1710b_A2362(vdh)
BPLBURPS1106A_A1068(vdh)
BPSEBDL_4062
BPSMBBQ_5362
BPSUBBN_4234
BPSDBBX_5900
BPZBP1026B_II0859
BPQBPC006_II1092
BPSHDR55_4561
BPSABBU_5258
BHGI6G56_00145
BUDAQ610_19075
BVIBcep1808_3842
BVEAK36_4869
BURBcep18194_B0051
BCMBcenmc03_4594
BCHBcen2424_5635
BCJBCAM2792
BCENDM39_5053
BCEWDM40_3359
BCEOI35_6671
BAMBamb_4915
BACBamMC406_5464
BMJBMULJ_05314(xylC)
BMUBmul_3211
BMKDM80_4591
BMULNP80_3342
BCTGEM_5615
BCEDDM42_5196
BCEPAPZ15_24555
BDLAK34_5014
BPYRABD05_21675
BCONNL30_17805
BUBBW23_3980
BDFWI26_26520
BLATWK25_29375
BTEIWS51_10600
BSEMWJ12_33820
BPSLWS57_00305
BMECWJ16_32330
BSTGWT74_32685
BSTLBBJ41_27780
BANNJFN94_17980
BARINLX30_23170
BAENL3V59_29125
BGLbglu_2g10510
BGUKS03_4870
BUGBC1001_3918
BGFBC1003_5482
BGDbgla_2g14150
BGOBM43_5084
BUKMYA_3498
BULBW21_6348
BUQAC233_21880
BGPBGL_2c16140
BPLAbpln_2g16810
BURKDM992_25720
BGEBC1002_5524
BPXBUPH_00502
BPYBphyt_4023
PSPWBJG93_19805
PARBCJU94_22035 CJU94_37955 CJU94_39145
PHSC2L64_47320
PTERC2L65_07685
PGPCUJ91_21645
PCJCUJ87_23300
PTSCUJ90_22610
PGISI6I06_26895
PACPFAZ97_28990
PACSFAZ98_16195
PBRYNDK50_23395
PSAAQEN71_19410
PKFRW095_18925
PPKU875_18595
PPNODA70_11110
PPNMLV28_19945
PRBX636_15515
PPULRO07_14155
PSPUNA29_22955
PAPISG18_13980
PVEUC34_05420
POXMB84_09810
PFGAB870_16390
PNRAT302_01615
PANDDRB87_04710
PFIBPI93_022980
PCOMNTU39_06280
TCARU0034_24190
AFQAFA_05560
AAQUD3M96_07100
AAMMFE795_05630
ODIODI_R0108
OUEI6G29_08420
HYLLPB072_14055
MASWAM586_11540
MLIRLPB04_14320
MALIEYF70_13785
MUMFCL38_05960
MFLAGO485_00005
DZOSR858_13150
TMJP0M04_23775
RBUPG1C_13655
EBAebA5381(pdh)
ABREpbN1_03720
APETToN1_39380(hbd)
AZAAZKH_2916
AZIAzCIB_2864
AZDCDA09_15570
THUAC731_016435
MESOBSQ44_07680 BSQ44_07715
NIYFQ775_09720
ORMHTY61_03480 HTY61_03510 HTY61_11410
NEOCYG48_17655 CYG48_17685 CYG48_19615
BMEEDK62_1020
BMCBAbS19_I03670
BAABAA13334_I03336
BABODK55_412
BABRDO74_1475
BABTDK49_175
BABBDK48_1715
BABUDK53_402
BABSDK51_1062
BABCDO78_319
BSIBS1330_I0368
BSFBSS2_I0361
BSUIBSSP1_I1331
BSUPBSPT1_I1344
BSUVBSPT2_I1328
BSUCBSSP2_I0387
BMTBSUIS_A0398
BSZDK67_1305
BSVBSVBI22_A0368
BSWIY71_01920
BSGIY72_01645
BCSBCAN_A0375
BSKBCA52141_I1100
BOLBCOUA_I0367
BCARDK60_458
BCASDA85_01780
BMRBMI_I372
BPPBPI_I401
BPVDK65_981
BCETV910_101580
BCEEV568_101772
BVLBF3285c1_1385
BRUBFS01_01890
BRJBKD03_08940
OINIAR37_05070
BIOBR141012304_10185
BPSNNIK97_11320
OCRHGK82_01655
BRCBCCGELA001_19040
BICLMTR13_23540
BARHWN72_25325
MOCBB934_00370
BRND1F64_16070 D1F64_16100
PSINCAK95_00265
PPHRAPZ00_16725 APZ00_21220
LAPACP90_21045
LABTFIU93_27345(vdh)
LAGGB0E33_04590
PHRC6569_00880
PSTGE8M01_18255
MALUKU6B_12120(vdh_2)
TGLHFZ77_10690
PSAPJHX88_11215
PTPRCA23_c08280 RCA23_c11110
RBGBG454_07570
PGVSL003B_3946 SL003B_3952
CACTHZ995_09705
PBAEP8S53_03095
NARSaro_3876
NPPPP1Y_AT15482 PP1Y_AT31801
NOGGKE62_05200
SBARH5V43_22220
SPHYCHN51_06860
ERYCP97_14110
NAOY958_22065
FERFNB15_12370
TXITH3_05185
THACCSC3H3_05075
TIIDY252_08200
TMKQGN29_03985
SKUSulku_2569
SULJSJPD1_1020
AVPAVENP_2145(ligV)
GMEGmet_2131(pcmO)
BSUBSU07350(yfmT)
BSLA7A1_1778
BSHBSU6051_07350(yfmT)
BSYI653_03700
BSUTBSUB_00809(yfmT)
BSULBSUA_00809(yfmT)
BSUSQ433_04140
BSOBSNT_07122(yfmT)
BSNBSn5_15585
BSQB657_07350(yfmT)
BSXC663_0761(yfmT)
BSPU712_03720
BSSBSUW23_03745(yfmT)
BSTGYO_0998
BITBIS30_14295
BLIBL02341(yfmT)
BLDBLi00757(yfmT)
BLHBaLi_c08520(yfmT)
BAYRBAM_007590
BAQBACAU_0727(yfmT)
BYABANAU_0674(yfmT)
BAMPB938_03600
BQYMUS_0743(yfmT)
BAMLBAM5036_0672(yfmT)
BAMARBAU_0731(yfmT)
BAMNBASU_0708(yfmT)
BAMBBAPNAU_0683(yfmT)
BAMTAJ82_04210
BAMYV529_06950(yfmT)
BMPNG74_00748(yfmT)
BAOBAMF_0704(yfmT)
BAZBAMTA208_03330(yfmT)
BQLLL3_00756(yfmT)
BXHBAXH7_00701(yfmT)
BAMIKSO_016030
BAMCU471_07380
BAMFU722_03730
BSIACWD84_18280
BAEBATR1942_01265
BVMB9C48_03740
BSONS101395_00950
BHTDIC78_06120
BMOJHC660_07820(aldY)
BTEQG4P54_03880(yfmT)
BIQAN935_03865
BSTRQI003_04060(yfmT)
BGYBGLY_0770(yfmT)
BCABEFK13_04230(yfmT)
BRYM0696_04215(yfmT)
BJSMY9_0829
BACPSB24_06090
BACBOY17_06420
BACOOXB_0406
BACYQF06_02580
BACLBS34A_08350(yfmT)
BALMBsLM_0775
BACSAUL54_07065
BHAIKJK41_03800
PARHI5S86_14470
BHABH1005
BKWBkAM31D_21970(yfmT_1) BkAM31D_23915(yfmT_2)
BGIBGM20_18845
BKOCKF48_04245
OIHOB2707
GMCGY4MC1_0573
GTHGeoth_0652
PTLAOT13_19020
PARGPspKH34_28800(yfmT_1) PspKH34_32090(yfmT_2)
LYCFH508_0021015
LYPMTP04_10700(yfmT)
HSANMUN89_21670
HSHIMUO14_13065
HAMYMUO15_00635 MUO15_11815
TAPGZ22_00685 GZ22_03450
TAIDKS242_01935 KS242_04290
VHLBME96_13700
VIGBKP57_17310
VPNA21D_00209(yfmT)
VIMGWK91_15350
VPTKBP50_12330
VNTOLD84_13555
ACOPRI196_05995
BTHVCQJ30_03935
PSYHD0S48_18450
GRCGI584_16665
MSEMGMB29_12620
BLENNCTC4824_01338(yfmT) NCTC4824_03756(xylC)
SEDDERJ70_01890
BVQFHE72_08460
RMFD5E69_05405
RAZU9J35_08490
BOUI5818_12725
MJOFOF60_09205
FHLOE105_01330
FAFOE104_10110
ALKLMM271_12670
BBEBBR47_43520(yfmT)
PAEJH70737_14345
PNPIJ22_36420
PVOPVOR_20094
PCHIPC41400_18075
PUIPUW25_13520
PPOGQPK24_13500
PPABKET34_13180
ADAUNZD86_06105 NZD86_22820
AFASNZD89_03390
EFFskT53_32150(yfmT)
SIVSSIL_1283
SSILSOLI23_11945
PKUAUO94_08365
PRTAUC31_04380
PLLI858_000080
PMARB0X71_02590
PFAEAJGP001_08870
PLXCW734_07095
PMATBBI11_06520
PDECH1Q58_05670
PLAYDNR44_011910
KPULGXN76_11575
KEBGXN75_03255
CBOLCGC65_21120
CASPNQ535_04485
WHJH9Q79_14645
MSGMSMEI_3943
MSBLJ00_20045
MSNLI99_20050
MSHLI98_20055
NAHF5544_32645
REBXU06_30275
ROAPd630_LPD13001
GMGNWF22_15200
SCBSCAB_8501 SCAB_90291 SCAB_90411
SRCM271_05750
SMALSMALA_7253
SSOII1A49_40035
STRCAA958_29200
SGSAVL59_24630
SGMGCM10017557_07850 GCM10017557_16470(vdh)
SCADDN051_10980
SALUDC74_158
SALLSAZ_01235
SPLULK06_028975
SGEDWG14_00022(vdh_1) DWG14_00485(vdh_2) DWG14_00642(vdh_3) DWG14_00655(vdh_4)
SAQUEJC51_41730 EJC51_45985
SPHVF9278_43480
SCHACP983_11020
SBATG4Z16_30585
SLFJEQ17_06705
SDECL3078_41400
SAKBK1J60_02305
SCAEIHE65_03295
SANTQR300_04790
SCYNN8I84_37475
ACRYAC20117_15900
KFVAS188_04780
KQIF1D05_29780
FRIFraEuI1c_5700
AOIAORI_5375
ARHDVSH64_25495
SESPBN6_43980(doxF)
SSYIEKG83_33900
KBUQ4V64_44945
LEDBBK82_40145
CROSN8J89_26845
ACTNL083_4519(ald1)
AFSAFR_19320
CCAZCOUCH_24280
SNASnas_2329
SBAEDSM104329_02441(yfmT)
RLCK227x_25220(yfmT)
 » show all
Reference
1  [PMID:6870241]
  Authors
Pometto AL 3rd, Crawford DL.
  Title
Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus.
  Journal
Appl Environ Microbiol 45:1582-5 (1983)
DOI:10.1128/AEM.45.5.1582-1585.1983
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.67
IUBMB Enzyme Nomenclature: 1.2.1.67
ExPASy - ENZYME nomenclature database: 1.2.1.67
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.67
BRENDA, the Enzyme Database: 1.2.1.67
CAS: 189767-93-9

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