Entry |
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Name |
fluoroacetaldehyde dehydrogenase
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Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
fluoroacetaldehyde:NAD+ oxidoreductase
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Reaction(IUBMB) |
fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+ [RN: R07156]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
The enzyme from Streptomyces cattleya has a high affinity for fluoroacetate and glycolaldehyde but not for acetaldehyde.
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History |
EC 1.2.1.69 created 2003
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Reference |
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Authors |
Murphy CD, Moss SJ, O'Hagan D. |
Title |
Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya. |
Journal |
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Sequence |
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Reference |
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Authors |
Murphy CD, Schaffrath C, O'Hagan D. |
Title |
Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 1.2.1.69 |
ExPASy - ENZYME nomenclature database: | 1.2.1.69 |
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