KEGG   ENZYME: 1.2.1.82
Entry
EC 1.2.1.82                 Enzyme                                 
Name
beta-apo-4'-carotenal oxygenase;
beta-apo-4'-carotenal dehydrogenase;
YLO-1;
carD (gene name)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
4'-apo-beta,psi-carotenal:NAD+ oxidoreductase
Reaction(IUBMB)
4'-apo-beta,psi-caroten-4'-al + NAD+ + H2O = neurosporaxanthin + NADH + 2 H+ [RN:R09783]
Reaction(KEGG)
R09783
Substrate
4'-apo-beta,psi-caroten-4'-al [CPD:C19892];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
neurosporaxanthin [CPD:C08607];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Neurosporaxanthin is responsible for the orange color of of Neurospora.
History
EC 1.2.1.82 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K17819  beta-apo-4'-carotenal oxygenase
Genes
QSU111994687 112021285
NCRNCU04013(ylo-1)
NTENEUTE1DRAFT140784(NEUTE1DRAFT_140784)
SMPSMAC_06187
PANPODANSg936
TTTTHITE_2110821
MTMMYCTH_2307429
CTHRCTHT_0045070
MGRMGG_07270
TMNUCRPA7_4168
SSCKSPSK_05142
FGRFGSG_09960
FPUFPSE_03856
FVRFVEG_02675
FOXFOXG_05463
NHENECHADRAFT_61128
TRETRIREDRAFT_74502
TRRM419DRAFT_101618
MAWMAC_03864
MAJMAA_02951
CMTCCM_09155
PLJVFPFJ_08615
VALVDBG_04258
VDAVDAG_01487
CFJCFIO01_01475 CFIO01_11498
SAPOSAPIO_CDS10721
ELAUCREL1_1920
PFYPFICI_06386
SSLSS1G_10799
BFUBCIN_04g05680(Bchfd1)
MBEMBM_07141
PSCOLY89DRAFT_647434
GLZGLAREA_10198
ANIAN5644.2
AFMAFUA_4G13500
ACTACLA_052470
NFINFIA_102870
AORAO090009000222
ANGANI_1_1254014(An01g09260)
AFVAFLA_011134
ALUCAKAW2_20980A
ACHEACHE_10403A
APUUAPUU_41014A APUU_60997S
PCSPc22g03630
PDPPDIP_43940
TMFPMAA_080520 PMAA_089200
TRGTRUGW13939_10770
CIMCIMG_00543
CPWCPC735_056920
UREUREG_00562
PBLPAAG_06961
PBNPADG_01495
ABEARB_07806
TVETRV_07386
AJEHCAG_07063
BGHBDBG_04911
PNOSNOG_05777
PTEPTT_13172
BZECOCCADRAFT_101773
BSCCOCSADRAFT_32828
BORCOCMIDRAFT_108997
AALTCC77DRAFT_926989
ZTRMYCGRDRAFT_98253
PFJMYCFIDRAFT_135796
BCOMBAUCODRAFT_38526
NPAUCRNP2_5491
TMLGSTUM_00011869001
FMEFOMMEDRAFT_147683
 » show all
Reference
1  [PMID:18627463]
  Authors
Estrada AF, Youssar L, Scherzinger D, Al-Babili S, Avalos J
  Title
The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway.
  Journal
Mol Microbiol 69:1207-20 (2008)
DOI:10.1111/j.1365-2958.2008.06349.x
  Sequence
[ncr:NCU04013]
Reference
2  [PMID:21749649]
  Authors
Diaz-Sanchez V, Estrada AF, Trautmann D, Al-Babili S, Avalos J
  Title
The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi.
  Journal
FEBS J 278:3164-76 (2011)
DOI:10.1111/j.1742-4658.2011.08242.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.82
IUBMB Enzyme Nomenclature: 1.2.1.82
ExPASy - ENZYME nomenclature database: 1.2.1.82
BRENDA, the Enzyme Database: 1.2.1.82

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