KEGG ENZYME: 1.2.1.92

ENZYME: 1.2.1.92

Entry

EC 1.2.1.92                 Enzyme

Name

3,6-anhydro-alpha-L-galactose dehydrogenase

Class

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

Sysname

3,6-anhydro-alpha-L-galactopyranose:NAD(P)+ 1-oxidoredutase

Reaction(IUBMB)

3,6-anhydro-alpha-L-galactopyranose + NAD(P)+ + H2O = 3,6-anhydro-L-galactonate + NAD(P)H + H+ [RN:R10861 R10862]

Reaction(KEGG)

R10861 R10862

Substrate

3,6-anhydro-alpha-L-galactopyranose [CPD:C20902];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]

Product

3,6-anhydro-L-galactonate [CPD:C20903];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

The enzyme, characterized from the marine bacterium Vibrio sp. EJY3, is involved in a degradation pathway for 3,6-anhydro-alpha-L-galactose, a major component of the polysaccharides produced by red macroalgae, such as agarose and porphyran.

History

EC 1.2.1.92 created 2014

Orthology

K20548

3,6-anhydro-alpha-L-galactose dehydrogenase

Genes

VEJ:	VEJY3_09240

VAS:	GT360_06750(aldA)

Reference

1 [PMID:25156229]

Authors

Yun EJ, Lee S, Kim HT, Pelton JG, Kim S, Ko HJ, Choi IG, Kim KH

Title

The novel catabolic pathway of 3,6-anhydro-L-galactose, the main component of red macroalgae, in a marine bacterium.

Journal

Environ Microbiol 17:1677-88 (2015)
DOI:10.1111/1462-2920.12607

Sequence

[vej:VEJY3_09240]

Other DBs

ExplorEnz - The Enzyme Database:

1.2.1.92

IUBMB Enzyme Nomenclature:

1.2.1.92

ExPASy - ENZYME nomenclature database:

1.2.1.92

BRENDA, the Enzyme Database:

1.2.1.92

DBGET integrated database retrieval system