KEGG   ENZYME: 1.2.1.97Help
Entry
EC 1.2.1.97                 Enzyme                                 

Name
3-sulfolactaldehyde dehydrogenase;
SLA dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(2S)-3-sulfolactaldehyde:NAD(P)+ oxidoreductase
Reaction(IUBMB)
(2S)-3-sulfolactaldehyde + NAD(P)+ + H2O = (2S)-3-sulfolactate + NAD(P)H + H+ [RN:R11677 R11678]
Reaction(KEGG)
Substrate
(2S)-3-sulfolactaldehyde [CPD:C21181];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
(2S)-3-sulfolactate [CPD:C11499];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the bacterium Pseudomonas putida SQ1, participates in a sulfoquinovose degradation pathway. Also acts on succinate semialdehyde.
History
EC 1.2.1.97 created 2015
Reference
1  [PMID:26195800]
  Authors
Felux AK, Spiteller D, Klebensberger J, Schleheck D
  Title
Entner-Doudoroff pathway for sulfoquinovose degradation in Pseudomonas putida SQ1.
  Journal
Proc Natl Acad Sci U S A 112:E4298-305 (2015)
DOI:10.1073/pnas.1507049112
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.97
IUBMB Enzyme Nomenclature: 1.2.1.97
ExPASy - ENZYME nomenclature database: 1.2.1.97
BRENDA, the Enzyme Database: 1.2.1.97

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