KEGG   ENZYME: 1.2.99.10
Entry
EC 1.2.99.10                Enzyme                                 

Name
4,4'-diapolycopenoate synthase;
crtNc;
4,4'-diapolycopenealdehyde oxidase (misleading)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With unknown physiological acceptors
Sysname
4,4'-diapolycopen-4-al,donor:oxygen oxidoreductase (4,4'-diapolycopen-4-oate-forming)
Reaction(IUBMB)
(1) 4,4'-diapolycopen-4-al + H2O + acceptor = 4,4'-diapolycopen-4-oate + reduced acceptor [RN:R11913];
(2) 4,4'-diapolycopene-4,4'-dial + 2 H2O + 2 acceptor = 4,4'-diapolycopene-4,4'-dioate + 2 reduced acceptor [RN:R11914]
Reaction(KEGG)
R11913 R11914
Substrate
4,4'-diapolycopen-4-al [CPD:C21766];
H2O [CPD:C00001];
acceptor [CPD:C00028];
4,4'-diapolycopene-4,4'-dial [CPD:C19798]
Product
4,4'-diapolycopen-4-oate [CPD:C21768];
reduced acceptor [CPD:C00030];
4,4'-diapolycopene-4,4'-dioate [CPD:C21770]
Comment
The enzyme has been described from the bacteria Methylomonas sp. 16a and Bacillus indicus.
History
EC 1.2.99.10 created 2017
Pathway
ec00906  Carotenoid biosynthesis
Orthology
K22445  4,4'-diapolycopenoate synthase
K25072  4,4'-diapolycopenoate synthase
Genes
MMT: Metme_3773
MDN: JT25_002370
MDH: AYM39_15935
MKO: MKLM6_3291
METL: U737_16975
MPSY: CEK71_14810
SDO: SD1155_11615
BTY: Btoyo_3622
BMYC: DJ92_5010
BACO: OXB_1856
LSP: Bsph_1280
PSYO: PB01_05270
SAU: SA1736(aldH)
SAV: SAV1920(aldH)
SAW: SAHV_1905(aldH)
SAM: MW1861(aldH)
SAS: SAS1844
SAR: SAR2013
SAC: SACOL1984(aldA2)
SAX: USA300HOU_1923(aldH1)
SAA: SAUSA300_1901(aldA2)
SAE: NWMN_1858
SAD: SAAV_1988(aldA2)
SUE: SAOV_2023
SUJ: SAA6159_01852(aldH)
SUK: SAA6008_01942(aldH)
SUZ: MS7_1956
SUG: SAPIG2015
SAUA: SAAG_02441
SAUE: RSAU_001807(aldA)
SAUS: SA40_1762
SAUU: SA957_1846
SAUG: SA268_1918
SAUT: SAI1T1_2014580(aldH)
SAUJ: SAI2T2_1014590(aldH)
SAUK: SAI3T3_1014580(aldH)
SAUQ: SAI4T8_1014590(aldH)
SAUV: SAI7S6_1014590(aldH)
SAUW: SAI5S5_1014530(aldH)
SAUX: SAI6T6_1014550(aldH)
SAUY: SAI8T7_1014570(aldH)
SAUF: X998_1976
SAB: SAB1857
SUY: SA2981_1878(aldH)
SAUB: C248_1998
SAUC: CA347_2010
SAUR: SABB_02345(aldH)
SAUI: AZ30_10235
SAUD: CH52_09320
SER: SERP1456(aldA-1)
SEP: SE1603
SEPP: SEB_01590
SEPS: DP17_549
SHA: SH1033(aldH)
SHH: ShL2_00921(aldH)
SSP: SSP0871
SCA: SCA_1490(aldH)
SDT: SPSE_0822(aldA2)
SDP: NCTC12225_00891(aldA2)
SPAS: STP1_0437
SCAP: AYP1020_1196(alkH)
SSCH: LH95_04115
SSCZ: RN70_04335
SAGQ: EP23_05765
SARL: SAP2_09350
SPIC: SAMEA4384060_1031(aldH)
SSH: NCTC13712_01941(calB)
SSIM: SAMEA4384339_1841(aldH)
SSTE: SAMEA4384403_0759(aldH)
MCL: MCCL_1656
MCAK: MCCS_21160(alkH)
PRI: PRIO_6478(ywdH)
SIV: SSIL_3201
JEO: JMA_12520
KZO: NCTC404_00258(calB_1)
EMU: EMQU_0481
CBK: CLL_A1665
CBT: CLH_1516
CBE: Cbei_1953
CBZ: Cbs_1953
CBEI: LF65_06115
CSB: CLSA_c15210(ywdH)
AOE: Clos_0626
 » show all
Reference
1  [PMID:15933032]
  Authors
Tao L, Schenzle A, Odom JM, Cheng Q
  Title
Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde.
  Journal
Appl Environ Microbiol 71:3294-301 (2005)
DOI:10.1128/AEM.71.6.3294-3301.2005
  Sequence
Reference
2  [PMID:25326460]
  Authors
Steiger S, Perez-Fons L, Cutting SM, Fraser PD, Sandmann G
  Title
Annotation and functional assignment of the genes for the C30 carotenoid pathways from the genomes of two bacteria: Bacillus indicus and Bacillus firmus.
  Journal
Microbiology 161:194-202 (2015)
DOI:10.1099/mic.0.083519-0
Other DBs
ExplorEnz - The Enzyme Database: 1.2.99.10
IUBMB Enzyme Nomenclature: 1.2.99.10
ExPASy - ENZYME nomenclature database: 1.2.99.10
BRENDA, the Enzyme Database: 1.2.99.10

DBGET integrated database retrieval system