KEGG   ENZYME: 1.20.1.1Help
Entry
EC 1.20.1.1                 Enzyme                                 

Name
phosphonate dehydrogenase;
NAD:phosphite oxidoreductase;
phosphite dehydrogenase
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
phosphonate:NAD+ oxidoreductase
Reaction(IUBMB)
phosphonate + NAD+ + H2O = phosphate + NADH + H+ [RN:R05746]
Reaction(KEGG)
Substrate
phosphonate [CPD:C06701];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
phosphate [CPD:C00009];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
NADP+ is a poor substitute for NAD+ in the enzyme from Pseudomonas stutzeri WM88.
History
EC 1.20.1.1 created 2001
Orthology
K18916  phosphonate dehydrogenase
Genes
SEEC: CFSAN002050_01105
ENX: NI40_012445
KPN: KPN_pKPN3p05892
KPH: KPNIH24_26515
KPG: KPNIH32_28465
KPC: KPNIH10_26805
KPJ: N559_5253
KPA: KPNJ1_05518
KPX: PMK1_a00057(ptxD)
KPNE: KU54_00065
KPNU: LI86_26935
PAEU: BN889_06572(ghrB1)
PMAN: OU5_P0288(ptxD)
MHC: MARHY1923(ptxD)
MEJ: Q7A_2703
TGR: Tgr7_0911
RME: Rmet_2992(ptxD)
CGD: CR3_2656
BMK: DM80_1401(ptxD) DM80_6100(ptxD)
PUT: PT7_2831
DAC: Daci_2673
CTES: O987_10360
RTA: Rta_30250
HAR: HEAR3214(ptxD)
MMS: mma_3043
OFO: BRW83_0327(ptxD)
GCA: Galf_2928
DEU: DBW_3423
MDI: METDI0356(ptxD)
MAQU: Maq22A_5p70080(ldhA)
FIL: BN1229_v1_0982(ptxD)
FIY: BN1229_v1_0986(ptxD)
SPSE: SULPSESMR1_03725(ptxD)
SYND: KR52_11170
CYT: cce_2560
TER: Tery_0368
ANA: all8087
 » show all
Taxonomy
Reference
1  [PMID:11278981]
  Authors
Costas AM, White AK, Metcalf WW.
  Title
Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88.
  Journal
J Biol Chem 276:17429-36 (2001)
DOI:10.1074/jbc.M011764200
  Sequence
Reference
2  [PMID:11456941]
  Authors
Vrtis JM, White AK, Metcalf WW, van der Donk WA.
  Title
Phosphite dehydrogenase: an unusual phosphoryl transfer reaction.
  Journal
J Am Chem Soc 123:2672-3 (2001)
Other DBs
ExplorEnz - The Enzyme Database: 1.20.1.1
IUBMB Enzyme Nomenclature: 1.20.1.1
ExPASy - ENZYME nomenclature database: 1.20.1.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.20.1.1
BRENDA, the Enzyme Database: 1.20.1.1
CAS: 9031-35-0

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