KEGG ENZYME: 1.20.1.1

ENZYME: 1.20.1.1

Entry

EC 1.20.1.1                 Enzyme

Name

phosphonate dehydrogenase;
NAD:phosphite oxidoreductase;
phosphite dehydrogenase

Class

Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With NAD+ or NADP+ as acceptor

Sysname

phosphonate:NAD+ oxidoreductase

Reaction(IUBMB)

phosphonate + NAD+ + H2O = phosphate + NADH + H+ [RN:R05746]

Reaction(KEGG)

R05746

Substrate

phosphonate [CPD:C06701];
NAD+ [CPD:C00003];
H2O [CPD:C00001]

Product

phosphate [CPD:C00009];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

NADP+ is a poor substitute for NAD+ in the enzyme from Pseudomonas stutzeri WM88.

History

EC 1.20.1.1 created 2001

Orthology

K18916

phosphonate dehydrogenase

Genes

SEEC:

CFSAN002050_01105

ENX:	NI40_012445

ENZ:	G0034_21710(ptxD)

KPN:	KPN_pKPN3p05892

KPH:	KPNIH24_26515

KPG:	KPNIH32_28465

KPC:	KPNIH10_26805

KPJ:

N559_5253

KPA:	KPNJ1_05518

KPX:	PMK1_a00057(ptxD)

KPNE:

KU54_00065

KPNU:

LI86_26935

KOM:	HR38_28610

CIY:	HAP28_14735

TOE:	QMG90_19690(ptxD)

PAES:

SCV20265_1024

PAEU:

BN889_06572(ghrB1)

PPJ:	RK21_02919

PMOS:

O165_024050

PFN:	HZ99_13350

PMAN:

OU5_P0288(ptxD)

PSK:	U771_31795

PSMT:

MT1_3009

PHF:	NLY38_07980(ptxD)

PSC:	A458_08040

PSH:	Psest_0431

PBM:	CL52_03160

PKG:	LW136_13155(ptxD)

HPEG:

EAO82_15185

HAES:

LO767_17880(ptxD)

PBAU:

OS670_15255(ptxD)

MAQ:	Maqu_1281 Maqu_3239 Maqu_3990

MHC:	MARHY1923(ptxD)

MSR:	AU15_17790

MARI:

ACP86_13635

MLQ:	ASQ50_14210

MALL:

PBN92_06775

MSHE:

MAALD49_04690 MAALD49_40250

MMEE:

NLK58_16925

MAMM:

ABNF92_19775

MFLI:

ACGK9W_02035

ACW:	A0J50_18580

ADV:	DJ533_01650

SHP:	Sput200_3281

SCHK:

GII14_20815

SDEO:

D0436_23100

MEJ:

Q7A_2703

MPIN:

LGT42_006305

TGR:

Tgr7_0911

GHL:	GM160_03835

HAK:	KO116_01540

HAAH:

HALA3H3_720008(ptxD)

HANY:

LG409_15290

HAXI:

HAALTHF_31260n

NIK:	F5I99_12635

RMN:	TK49_01775

RME:	Rmet_2992(ptxD)

CGD:

CR3_2656

CUU:	BKK79_37720

BVI:	Bcep1808_7212

BMK:	DM80_1401(ptxD) DM80_6100(ptxD)

BAEN:

L3V59_44180

PUT:

PT7_2831

AALN:

Q3V95_04040

AAQU:

D3M96_16500

AAMM:

FE795_02080

ACIP:

CBP36_01760

ACIN:

CBP34_12135

ACIS:

CBP35_17180

ATEM:

PQV96_19565

DAC:

Daci_2673

CTES:

O987_10360

ADK:	Alide2_1986

RTA:

Rta_30250

HCZ:	G9Q37_06075

DIJ:	HND92_07935

DIM:	K2L43_08010

DIA:	Dtpsy_1417

ATER:

MW290_01895

HAR:	HEAR3214(ptxD)

MMS:

mma_3043

HHF:	E2K99_12370

OFO:	BRW83_0327(ptxD)

OAL:	NB647_01290

AON:	DEH84_08620

PCAZ:

ACMDW7_15040

SHD:	SUTH_02239

GCA:

Galf_2928

AHV:	AADV58_09880 AADV58_17560

BEB:	AEM42_00165

NRH:	T8J41_20080

RHV:	BA939_15910 BA939_16115 BA939_16375 BA939_16580

RROS:

D4A92_24580

BIC:	LMTR13_34860

BROS:

QUH67_22990

RBK:	E0H22_04240

MEA:	Mex_2p0360 Mex_2p1233(ptxD)

MDI:	METDI0356(ptxD)

MAQU:

Maq22A_5p70080(ldhA)

MOG:	MMB17_14420

MFUJ:

ABC766_31720

FIL:	BN1229_v1_0982(ptxD)

FIY:	BN1229_v1_0986(ptxD)

MAAD:

AZF01_22640

PSIN:

CAK95_23670

PPHR:

APZ00_01925 APZ00_04570 APZ00_05905 APZ00_17900 APZ00_19400 APZ00_24730

LABT:

FIU93_31395(ptxD)

SPSE:

SULPSESMR1_03725(ptxD)

RID:	RIdsm_05895(ptxD)

PALS:

PAF20_17915

SMUC:

JL100_031705

TII:	DY252_19230

THAR:

T8K17_25390

DEU:

DBW_3423

DEF:	CNY67_04440

DMS:	E8L03_15975

EFF:	skT53_29730

MSER:

MTY59_36920

GOS:	QAD21_13310

DKN:	NHB83_17725

DHM:	CYJ49_005170

BLY:	A2T55_11240

BRI:	FDF13_08575

BLUT:

EW640_10550

BSPO:

L1F31_18880

PAUT:

Pdca_70280

SYND:

KR52_11170

PMF:	P9303_11271

PMG:	P9301_12531

CYT:

cce_2560

TER:

Tery_0368

ANA:

all8087

NPU:	Npun_F3301

NSH:

GXM_08599

CALN:

NIES2098_31840

» show all

Reference

1 [PMID:11278981]

Authors

Costas AM, White AK, Metcalf WW

Title

Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88.

Journal

J Biol Chem 276:17429-36 (2001)
DOI:10.1074/jbc.M011764200

Sequence

[psc:A458_08040]

Reference

2 [PMID:11456941]

Authors

Vrtis JM, White AK, Metcalf WW, van der Donk WA.

Title

Phosphite dehydrogenase: an unusual phosphoryl transfer reaction.

Journal

J Am Chem Soc 123:2672-3 (2001)
DOI:10.1021/ja004301k

Other DBs

ExplorEnz - The Enzyme Database:

1.20.1.1

IUBMB Enzyme Nomenclature:

1.20.1.1

ExPASy - ENZYME nomenclature database:

1.20.1.1

UM-BBD (Biocatalysis/Biodegradation Database):

1.20.1.1

BRENDA, the Enzyme Database:

1.20.1.1

CAS:

9031-35-0

DBGET integrated database retrieval system