Entry
Name
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With disulfide as acceptor
BRITE hierarchy
Sysname
arseno-mycothiol:mycoredoxin oxidoreductase
Reaction(IUBMB)
arseno-mycothiol + mycoredoxin = arsenite + mycothiol-mycoredoxin disulfide
Substrate
arseno-mycothiol;
mycoredoxin
Product
arsenite [CPD:
C06697 ];
mycothiol-mycoredoxin disulfide
Comment
Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. The substrate arseno-mycothiol is formed by EC
2.8.4.2 (arsenate:mycothiol transferase). A second mycothiol recycles mycoredoxin and forms mycothione.
History
EC 1.20.4.3 created 2010
Orthology
Genes
PTAE : NCTC10697_03553(nrdH)
PSYC : DABAL43B_2691(nrdH)
MMAE : MMARE11_08170 MMARE11_13300
MLI : MULP_00894 MULP_01534
MPSE : MPSD_09960 MPSD_15490
MSHO : MSHO_26250 MSHO_59400
MKN : MKAN_18640 MKAN_21765
MBAI : MB901379_00737 MB901379_01246
MOT : LTS72_18465(mrx1) LTS72_21660
MDU : MDUV_11300 MDUV_27320
MDR : MDOR_05400 MDOR_09890
MGAD : MGAD_24480 MGAD_30830
MAUS : JN090_07930(mrx1) JN090_22900
MCHE : BB28_17980 BB28_23990
MIZ : BAB75_20105 BAB75_26525
MSTE : MSTE_00413 MSTE_03668 MSTE_04855
MSAO : MYCSP_16245 MYCSP_21965
MSAL : DSM43276_03337 DSM43276_04535
NBR : O3I_015565 O3I_033970 O3I_034645
NSR : NS506_01249 NS506_01826(mrx1) NS506_02184
NOZ : DMB37_12690 DMB37_13350
NOD : FOH10_02465 FOH10_04170
NAD : NCTC11293_02110 NCTC11293_05775
NWL : NWFMUON74_11260 NWFMUON74_14690
NIE : KV110_32680 KV110_33730
NHU : H0264_03820 H0264_11080 H0264_12880
NYU : D7D52_00110 D7D52_01660
RPY : Y013_03710 Y013_07335
RBY : CEJ39_14360 CEJ39_18255
RAV : AAT18_01145 AAT18_16900
RRZ : CS378_06465 CS378_17435
RHQ : IM25_17565 IM25_21650
RRT : 4535765_02552(mrx_1) 4535765_03290(mrx_2)
RCR : NCTC10994_03976(mrx)
RGOR : NMQ04_10750 NMQ04_14140
RHOP : D8W71_14220 D8W71_24920
RFA : A3L23_02884 A3L23_04837
RHS : A3Q41_00477 A3Q41_03432
SCO : SCO2989(SCE50.17c) SCO5187(2SC3B6.11c)
SANL : KZO11_25240 KZO11_32690
SGRF : SGFS_004670 SGFS_044250
SSX : SACTE_0177 SACTE_4417
SVL : Strvi_1505 Strvi_3479
STRP : F750_4714 F750_6695
SLV : SLIV_12445 SLIV_22755
SVT : SVTN_25120 SVTN_38460
STRM : M444_10930 M444_22730
SPRI : SPRI_1473 SPRI_2688
SCX : AS200_17910 AS200_38580
SLE : sle_25550(sle_25550)
SPAV : Spa2297_21900 Spa2297_27830
SALL : SAZ_01580 SAZ_28280
STRD : NI25_13240 NI25_23830
SAUO : BV401_29515 BV401_37635
SSIA : A7J05_12765 A7J05_35500
SALJ : SMD11_2362 SMD11_6208
SLX : SLAV_13680 SLAV_19615
SNZ : DC008_16530 DC008_23010
SGD : ELQ87_13480 ELQ87_37270
SCYA : EJ357_00515 EJ357_30605
SNQ : CP978_22285 CP978_32160
SVN : CP980_11715 CP980_33305
SNK : CP967_11090 CP967_15510
SHAW : CEB94_04705 CEB94_17725 CEB94_27140
SRK : FGW37_00810 FGW37_21685
SFIC : EIZ62_10880 EIZ62_29490
SVR : CP971_06205 CP971_12590
SGF : HEP81_00515 HEP81_02835
SSEO : D0Z67_19350 D0Z67_28925
SSUB : CP968_11900 CP968_16395
SCIN : CP977_22890 CP977_33015
SFUG : CNQ36_12625 CNQ36_23500
SPAC : B1H29_02565 B1H29_12630 B1H29_35585
SCHA : CP983_14795 CP983_39520
SGX : H4W23_25860 H4W23_26665
SCOE : CP976_03655 CP976_28525
SNF : JYK04_05543 JYK04_06528
SDD : D9753_01230 D9753_12135
SLF : JEQ17_03275 JEQ17_16705
SDUR : M4V62_01740 M4V62_15695
STAA : LDH80_02065 LDH80_14300
SVIO : HWN34_03805 HWN34_08765
STUB : MMF93_01045 MMF93_21960
SSPN : LXH13_26370 LXH13_37165
SLON : LGI35_02310 LGI35_28660
STEE : F3L20_05450 F3L20_17705
SGK : PET44_09550 PET44_21460
SROC : RGF97_10325 RGF97_32035
SCAY : PYS65_12145 PYS65_22815
KBU : Q4V64_00830 Q4V64_34720
SLUO : PS467_27005 PS467_38960
SCAJ : O1G22_02030 O1G22_14695
SCY : SCATT_40360 SCATT_p08710
KAU : B6264_01395 B6264_07645
CUM : NI26_05145 NI26_13945
CUB : BJK06_02315 BJK06_10525
CUG : C1N91_05075 C1N91_14285
CQF : GBG65_04340 GBG65_12635
CCIT : QPK07_05410 QPK07_14500
CUF : KM842_07930 KM842_15525
CUY : I8920_05115 I8920_13505
CPOI : OE229_00255 OE229_08260
FRP : AX769_08975 AX769_10525
CART : PA27867_1061 PA27867_2508
CRY : B7495_05275 B7495_12440
PSAI : C3B54_111353 C3B54_11636
LEU : Leucomu_01910 Leucomu_03160 Leucomu_03970
LTR : EVS81_04220 EVS81_05475 EVS81_11815
LEB : G7066_03885 G7066_04620
LVI : G7068_13025 G7068_14090
LLUT : K1X41_06265 K1X41_12570
MANT : BHD05_04210 BHD05_13640
FRN : F1C15_03690 F1C15_05805
ACRY : AC20117_05540 AC20117_19360
ASUF : MNQ99_09755 MNQ99_15160
MLY : CJ228_000770 CJ228_008840
IVA : Isova_0830 Isova_2010
SANW : G7063_09005 G7063_11145
JLI : EXU32_09055 EXU32_16530
JCR : O9K63_02060 O9K63_11415
PHW : G7075_02255 G7075_14250
AUS : IPK37_01090 IPK37_08430 IPK37_14140
HALT : IM660_05800 IM660_16195
NOY : EXE57_06105 EXE57_10950
NOO : FE634_07710 FE634_16860
NSN : EXE58_12565 EXE58_13540
AEB : C6I20_02665 C6I20_05165 C6I20_11530
NGV : CDO52_07885 CDO52_16935
NAKE : KGD83_06165 KGD83_12390
NCG : KGD84_05420 KGD84_18300
STRR : EKD16_04165 EKD16_24075
NOW : GBF35_23810 GBF35_44025
MHAI : OHB01_04130 OHB01_29955
AJA : AJAP_18275 AJAP_39750
AMYC : CU254_05165 CU254_36830
AMYB : BKN51_13600 BKN51_31410
AAB : A4R43_06075 A4R43_32710
AMYY : YIM_19335 YIM_45505(mrx1)
AORI : SD37_02480 SD37_21180
APRT : MUY14_30030 MUY14_39520
AROO : NQK81_00145 NQK81_23165
ARHD : VSH64_33910 VSH64_44340
AMOG : QRX60_04530 QRX60_14295
ACOR : LCL61_02300 LCL61_23805
LED : BBK82_23125 BBK82_46800
MTEM : GCE86_12510 GCE86_21060
MFEU : H1D33_01925 H1D33_22310
MPRN : Q3V37_11480 Q3V37_29125
MHAW : RMN56_16425 RMN56_25370
MICF : QQG74_26430 QQG74_27005
AMS : AMIS_63740 AMIS_73350
ACTN : L083_7266 L083_7950
ACTL : L3i22_088870 L3i22_099350
ASIC : Q0Z83_096540 Q0Z83_106270
AOU : ACTOB_006884 ACTOB_007950
ACTE : ACTI_03940 ACTI_13440
PLAB : C6361_14735 C6361_16030 C6361_29845
PLAT : C6W10_10430 C6W10_14355
CATI : CS0771_19840 CS0771_48880
DFU : Dfulv_05670 Dfulv_13170
DAUR : Daura_05020 Daura_13890
CCAZ : COUCH_02235 COUCH_06180
BLON : BLIJ_0762 BLIJ_0772
PLAN : A1s21148_02485 A1s21148_04615
PLAK : A1s21155_00945 A1s21155_04470
PLIM : PHILAsVB114_02470 PHILAsVB114_04545
PSUF : A1sIA56_00950 A1sIA56_04385
PVS : A1sIA79_00920 A1sIA79_04250
PVN : A7sIIA15_02575 A7sIIA15_04830
NAB : B1sIIB91_01355 B1sIIB91_04020
DEW : DGWBC_0594 DGWBC_1339
DFO : Dform_01178(mrx1) Dform_01386(mrx1)
DETH : HX448_07235 HX448_08450
KBB : ccbrp13_22190 ccbrp13_25930
MSV : Mesil_0413 Mesil_0606 Mesil_2973
» show all
Taxonomy
Reference
Authors
Ordonez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J
Title
Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.20.4.3
ExPASy - ENZYME nomenclature database: 1.20.4.3