KEGG   ENZYME: 1.20.4.3
Entry
EC 1.20.4.3                 Enzyme                                 

Name
mycoredoxin;
Mrx1;
MrxI
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With disulfide as acceptor
Sysname
arseno-mycothiol:mycoredoxin oxidoreductase
Reaction(IUBMB)
arseno-mycothiol + mycoredoxin = arsenite + mycothiol-mycoredoxin disulfide
Substrate
arseno-mycothiol;
mycoredoxin
Product
arsenite [CPD:C06697];
mycothiol-mycoredoxin disulfide
Comment
Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. The substrate arseno-mycothiol is formed by EC 2.8.4.2 (arsenate:mycothiol transferase). A second mycothiol recycles mycoredoxin and forms mycothione.
History
EC 1.20.4.3 created 2010
Orthology
K18917  mycoredoxin
Genes
XSA: SB85_08035
XHY: FZ025_03710
PSU: Psesu_2304
LGU: LG3211_3722
LEM: LEN_1391
LUS: E5843_11260
XBC: ELE36_14810
DKO: I596_3074
PMY: Pmen_3551
PMK: MDS_3817
PPSE: BN5_1020
PFL: PFL_1059
PPRO: PPC_1096
PFS: PFLU_1048
PFB: VO64_4172
PMAN: OU5_2414
PSOS: POS17_1056
PANR: A7J50_1055
PSIL: PMA3_04310
PALL: UYA_18335
PSYC: DABAL43B_2691(nrdH)
FBL: Fbal_0419
CJA: CJA_1891
SAGA: M5M_05175
SVA: SVA_2813
DAR: Daro_3678
GEB: GM18_1271
MCG: GL4_2180
PZU: PHZ_p0073
SSAN: NX02_p0320
BTS: Btus_2511
MTU: Rv3198A
MTC: MT3292
MRA: MRA_3235
MTUR: CFBS_3383
MTD: UDA_3198A
MTUC: J113_22285
MTUE: J114_17120
MTUH: I917_22450
MTUL: TBHG_03129
MTUT: HKBT1_3370
MTUU: HKBT2_3377
MBB: BCG_3223
MBT: JTY_3218
MBX: BCGT_3063
MAF: MAF_32060
MMIC: RN08_3528
MPA: MAP_3298
MAO: MAP4_0487
MAVI: RC58_02350
MAVU: RE97_02355
MAV: MAV_4144
MIT: OCO_40040
MIA: OCU_39950
MID: MIP_06036
MYO: OEM_40320
MIR: OCQ_41140
MLP: MLM_3305
MMC: Mmcs_1408
MKM: Mkms_1426
MJL: Mjls_1462
MMM: W7S_19955
MHAD: B586_17065
MSHG: MSG_01277
MGI: Mflv_4661
MVQ: MYVA_1556
MHAS: MHAS_00588
MAB: MAB_3512
MABB: MASS_3541
MMIN: MMIN_06130
ASD: AS9A_3745
CGL: NCgl0808(Cgl0842)
CGB: cg0964
CGU: WA5_0808
CGT: cgR_0957
CGM: cgp_0964(mrx1)
CGJ: AR0_04770
CEF: CE0917
CDI: DIP0823
CPSE: CPTA_01181
CPSU: CPTB_00351
CPSF: CPTC_01172
CVA: CVAR_0650
CTER: A606_02885
COA: DR71_1547
CSP: WM42_0573
CPHO: CPHO_09105
CGV: CGLAU_03615(mrx1)
CAQU: CAQU_03715
CAMG: CAMM_09560
CPEG: CPELA_07760(mrx1)
CEE: CENDO_03550(mrx1)
NFA: NFA_45340
RER: RER_22230
REY: O5Y_10635
ROP: ROP_64420
REQ: REQ_32710(mrx)
RRT: 4535765_02552(mrx_1) 4535765_03290(mrx_2)
RCR: NCTC10994_03976(mrx)
GBR: Gbro_3497
GOR: KTR9_3525
TPR: Tpau_3048
SRT: Srot_2147
SCO: SCO5187(2SC3B6.11c)
SGR: SGR_2338
SCT: SCAT_4050
SHY: SHJG_6294
SVE: SVEN_4839
SALS: SLNWT_2113
SFI: SFUL_4998
STRE: GZL_03520
SLD: T261_2863
SLE: sle_25550(sle_25550)
SMAL: SMALA_5141
SLAU: SLA_5021
SFK: KY5_5307c
SRJ: SRO_2624
KSK: KSE_48950
LXL: KDY119_01009(mrx1)
LXX: Lxx07480(grx)
CMI: CMM_2111
CMS: CMS1110
CMC: CMN_02076
MTS: MTES_1098
MOO: BWL13_00232(mrx1)
ART: Arth_2324
ARM: ART_1003
AAU: AAur_2316
ACH: Achl_2050
BCV: Bcav_2898
JDE: Jden_0714
LMOI: VV02_19050
XCE: Xcel_0785
IDO: I598_1426
CFL: Cfla_2470
CFI: Celf_1170
SERJ: SGUI_1205
MPH: MLP_31620
NCA: Noca_1515
NDK: I601_0063
KFL: Kfla_5338
PSIM: KR76_09295
TFU: Tfu_0529
NAL: B005_1399
TCU: Tcur_3744
FAL: FRAAL6039
ACE: Acel_1772
GOB: Gobs_4233
MMAR: MODMU_4631
SEN: SACE_7370
AMN: RAM_45370
AMM: AMES_8706
AMZ: B737_8707
AMYY: YIM_19335 YIM_45505(mrx1)
PSEA: WY02_21700
PSEE: FRP1_21490
PSEH: XF36_19845
PAUT: Pdca_12240
AMI: Amir_5740
SESP: BN6_68780
ACTI: UA75_30710
ACAD: UA74_30175
SAQ: Sare_4121
ASE: ACPL_7612
ACTS: ACWT_7482
CAI: Caci_7800
SNA: Snas_1785
BLJ: BLD_0096(grxC1)
BLF: BLIF_1412
BLL: BLJ_1398
BLB: BBMN68_125(grxC1)
BLM: BLLJ_1367
BLK: BLNIAS_00839(grxC1)
BLG: BIL_00780
BBP: BBPR_0160
BBI: BBIF_0198
BBF: BBB_0156(grxC)
BBRU: Bbr_0642
BBRE: B12L_0557
BBRV: B689b_0650
BBRJ: B7017_0602
BBRC: B7019_0613
BBRN: B2258_0608
BBRS: BS27_0642
BBRD: BBBR_0587
BTP: D805_0190
BCAT: BBCT_0503
BPSC: BBPC_0553
BSCA: BBSC_0213
TBI: Tbis_2967
DFO: Dform_01178(mrx1) Dform_01386(mrx1)
ATM: ANT_20770
DGE: Dgeo_1508
DDR: Deide_06390(nrdH)
DGO: DGo_CA2073(grxA)
DFC: DFI_10690
TRA: Trad_1206
MRB: Mrub_0332
ACA: ACP_1054
ABAS: ACPOL_0151
CTS: Ctha_1917
NDE: NIDE3573
NJA: NSJP_0424
SAAL: L336_0888
 » show all
Reference
1  [PMID:19286650]
  Authors
Ordonez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J
  Title
Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.
  Journal
J Biol Chem 284:15107-16 (2009)
DOI:10.1074/jbc.M900877200
  Sequence
[cgl:NCgl0808]
Other DBs
ExplorEnz - The Enzyme Database: 1.20.4.3
IUBMB Enzyme Nomenclature: 1.20.4.3
ExPASy - ENZYME nomenclature database: 1.20.4.3
BRENDA, the Enzyme Database: 1.20.4.3

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