KEGG   ENZYME: 1.20.9.1Help
Entry
EC 1.20.9.1                 Enzyme                                 

Name
arsenate reductase (azurin);
arsenite oxidase (ambiguous)
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With a copper protein as acceptor
BRITE hierarchy
Sysname
arsenite:azurin oxidoreductase
Reaction(IUBMB)
arsenite + H2O + 2 oxidized azurin = arsenate + 2 reduced azurin + 2 H+ [RN:R05751]
Reaction(KEGG)
R05751;
(other) R09787
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Substrate
arsenite [CPD:C06697];
H2O [CPD:C00001];
oxidized azurin [CPD:C05357]
Product
arsenate [CPD:C11215];
reduced azurin [CPD:C05358];
H+ [CPD:C00080]
Comment
Contains a molybdopterin centre comprising two molybdopterin guanosine dinucleotide cofactors bound to molybdenum, a [3Fe-4S] cluster and a Rieske-type [2Fe-2S] cluster. Isolated from beta-proteobacteria. Also uses a c-type cytochrome or O2 as acceptors.
History
EC 1.20.9.1 created 2001 as EC 1.20.98.1, transferred 2011 to EC 1.20.9.1
Orthology
K08355  arsenite oxidase small subunit
K08356  arsenite oxidase large subunit
Genes
VSP: VS_II0658 VS_II0659
VTA: A0943 A0944 B1225 B1226
MBS: MRBBS_1242(aoxB) MRBBS_1243(aoxA)
MPQ: ABA45_06345
MVS: MVIS_1833(aoxA)
HSI: BOX17_13460 BOX17_13465
RSL: RPSI07_mp0919(aoxA) RPSI07_mp0920(aoxB)
CBW: RR42_s1794 RR42_s1795
CCUP: BKK81_17850 BKK81_17855 BKK81_22395
CUU: BKK79_24695 BKK79_24700
BMJ: BMULJ_05810(asoA) BMULJ_05811(asoB) BMULJ_05832(asoB) BMULJ_05833(asoA)
HAR: HEAR0478(aoxB) HEAR0479(aoxA)
THI: THI_3162(aoxB) THI_3163(aoxA)
SMUL: SMUL_3119(aioB) SMUL_3120(aioA)
AMIH: CO731_03145(aioB) CO731_03146(aioA)
RHT: NT26_p10029(aioB) NT26_p10030(aioA)
MSC: BN69_1400(aoxB) BN69_1401
RLI: RLO149_c022030(aoxA) RLO149_c022040(aoxB)
PMW: B2K_08810
TSC: TSC_c14680(aoxB) TSC_c14700(aoxA)
NDE: NIDE3704(aoxA) NIDE3705(aoxB)
 » show all
Taxonomy
Reference
1  [PMID:1331097]
  Authors
Anderson GL, Williams J, Hille R.
  Title
The purification and characterization of arsenite oxidase from Alcaligenes faecalis, a molybdenum-containing hydroxylase.
  Journal
J Biol Chem 267:23674-82 (1992)
  Sequence
Reference
2  [PMID:11250197]
  Authors
Ellis PJ, Conrads T, Hille R, Kuhn P.
  Title
Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A.
  Journal
Structure (Camb) 9:125-32 (2001)
DOI:10.1016/S0969-2126(01)00566-4
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.20.9.1
IUBMB Enzyme Nomenclature: 1.20.9.1
ExPASy - ENZYME nomenclature database: 1.20.9.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.20.9.1
BRENDA, the Enzyme Database: 1.20.9.1
CAS: 146907-46-2

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