KEGG   ENZYME: 1.20.9.1Help
Entry
EC 1.20.9.1                 Enzyme                                 

Name
arsenate reductase (azurin);
arsenite oxidase (ambiguous)
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With a copper protein as acceptor
BRITE hierarchy
Sysname
arsenite:azurin oxidoreductase
Reaction(IUBMB)
arsenite + H2O + 2 oxidized azurin = arsenate + 2 reduced azurin + 2 H+ [RN:R05751]
Reaction(KEGG)
R05751;
(other) R09787
Show
Substrate
arsenite [CPD:C06697];
H2O [CPD:C00001];
oxidized azurin [CPD:C05357]
Product
arsenate [CPD:C11215];
reduced azurin [CPD:C05358];
H+ [CPD:C00080]
Comment
Contains a molybdopterin centre comprising two molybdopterin guanosine dinucleotide cofactors bound to molybdenum, a [3Fe-4S] cluster and a Rieske-type [2Fe-2S] cluster. Isolated from beta-proteobacteria. Also uses a c-type cytochrome or O2 as acceptors.
History
EC 1.20.9.1 created 2001 as EC 1.20.98.1, transferred 2011 to EC 1.20.9.1
Orthology
K08355  arsenite oxidase small subunit
K08356  arsenite oxidase large subunit
Genes
VSP: VS_II0658 VS_II0659
VTA: A0943 A0944 B1225 B1226
MBS: MRBBS_1242(aoxB) MRBBS_1243(aoxA)
MPQ: ABA45_06345
MVS: MVIS_1833(aoxA)
MYA: MORIYA_1165 MORIYA_1166
HSI: BOX17_13460 BOX17_13465
RSL: RPSI07_mp0919(aoxA) RPSI07_mp0920(aoxB)
CUH: BJN34_21510 BJN34_21515
CBW: RR42_s1794 RR42_s1795
CCUP: BKK81_17850 BKK81_17855 BKK81_22395
CUU: BKK79_24695 BKK79_24700
BOC: BG90_1022 BG90_1023
BVE: AK36_5595 AK36_5596
BMU: Bmul_5678 Bmul_5679 Bmul_5703 Bmul_5704
BMJ: BMULJ_05810(asoA) BMULJ_05811(asoB) BMULJ_05832(asoB) BMULJ_05833(asoA)
BMK: DM80_6068 DM80_6069 DM80_6143 DM80_6144
PARB: CJU94_00385 CJU94_00390
PPNO: DA70_08845 DA70_08850
AXX: ERS451415_05769(aioB) ERS451415_05770(aioA)
RFR: Rfer_3084 Rfer_3085
OTK: C6570_08745 C6570_08750
HAR: HEAR0478(aoxB) HEAR0479(aoxA)
HEE: hmeg3_02275 hmeg3_02280
TIN: Tint_3061 Tint_3062
THI: THI_3162(aoxB) THI_3163(aoxA)
SULF: CAP31_08915 CAP31_08920
ATW: C0099_09795 C0099_09800
AZD: CDA09_11970 CDA09_11975
SBA: Sulba_2413 Sulba_2414
SMUL: SMUL_3119(aioB) SMUL_3120(aioA)
SHAL: SHALO_2876 SHALO_2877
SULS: Sdiek1_1026 Sdiek1_1027 Sdiek1_1028
AAK: AA2016_4246 AA2016_4247
AMIH: CO731_03145(aioB) CO731_03146(aioA)
SAME: SAMCFNEI73_pC1772(aioB) SAMCFNEI73_pC1773(aioA)
RHT: NT26_p10029(aioB) NT26_p10030(aioA)
NHA: Nham_4426 Nham_4427
XAU: Xaut_3949 Xaut_3950
SNO: Snov_1288 Snov_1289
MOC: BB934_26195 BB934_26200
CHEL: AL346_18905 AL346_18910
CDQ: BOQ54_03350 BOQ54_03355
MSC: BN69_1400(aoxB) BN69_1401
MROS: EHO51_05095 EHO51_05100
CSE: Cseg_2507 Cseg_2508
RLI: RLO149_c022030(aoxA) RLO149_c022040(aoxB)
PSF: PSE_5043 PSE_5044
CON: TQ29_15470 TQ29_15475
HAT: RC74_20735
DAA: AKL17_1594 AKL17_1595
SPSE: SULPSESMR1_00155(aioA) SULPSESMR1_00156(aioB)
AHT: ANTHELSMS3_01774(aioA) ANTHELSMS3_01775(aioB)
AMV: ACMV_26640 ACMV_26650 ACMV_P2_00160 ACMV_P2_00170
PGV: SL003B_2333 SL003B_2334
BCO: Bcell_2932
VIR: X953_02020
VHL: BME96_01380
PMS: KNP414_01413
PMQ: PM3016_1730
PMW: B2K_08810
CAU: Caur_1209 Caur_1210
CHL: Chy400_1322 Chy400_1323
CAG: Cagg_0377 Cagg_0378
TTJ: TTHB127 TTHB128
TTS: Ththe16_2239 Ththe16_2240
TSC: TSC_c14680(aoxB) TSC_c14700(aoxA)
TAQ: TO73_0834 TO73_0835
TBC: A0O31_02546 A0O31_02547
CPB: Cphamn1_2364 Cphamn1_2365
CLI: Clim_0382 Clim_0383
HHO: HydHO_0313 HydHO_0314
HYS: HydSN_0324 HydSN_0325
TRD: THERU_04625 THERU_04630
NDE: NIDE3704(aoxA) NIDE3705(aoxB)
HLC: CHINAEXTREME13385 CHINAEXTREME13390
APE: APE_2556.1 APE_2563
ACJ: ACAM_1597 ACAM_1598
STO: STK_23910 STK_23920
SULA: BFU36_12340 BFU36_12370
MCN: Mcup_1604 Mcup_1611
MHK: DFR87_05070 DFR87_05105
AHO: Ahos_1882 Ahos_1883
AMAN: B6F84_04000 B6F84_04010
ABRI: DFR85_00200 DFR85_00205 DFR85_00260
ASUL: DFR86_03900 DFR86_03910
PYR: P186_1845 P186_1846
POG: Pogu_0531 Pogu_0532
 » show all
Taxonomy
Reference
1  [PMID:1331097]
  Authors
Anderson GL, Williams J, Hille R.
  Title
The purification and characterization of arsenite oxidase from Alcaligenes faecalis, a molybdenum-containing hydroxylase.
  Journal
J Biol Chem 267:23674-82 (1992)
  Sequence
Reference
2  [PMID:11250197]
  Authors
Ellis PJ, Conrads T, Hille R, Kuhn P.
  Title
Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A.
  Journal
Structure (Camb) 9:125-32 (2001)
DOI:10.1016/S0969-2126(01)00566-4
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.20.9.1
IUBMB Enzyme Nomenclature: 1.20.9.1
ExPASy - ENZYME nomenclature database: 1.20.9.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.20.9.1
BRENDA, the Enzyme Database: 1.20.9.1
CAS: 146907-46-2

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