KEGG ENZYME: 1.20.9.1

ENZYME: 1.20.9.1

Entry

EC 1.20.9.1 Enzyme

Name

arsenate reductase (azurin);
arsenite oxidase (ambiguous)

Class

Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With a copper protein as acceptor

Sysname

arsenite:azurin oxidoreductase

Reaction(IUBMB)

arsenite + H2O + 2 oxidized azurin = arsenate + 2 reduced azurin + 2 H+ [RN:R05751]

Reaction(KEGG)

R05751;
(other) R09787

Substrate

arsenite [CPD:C06697];
H2O [CPD:C00001];
oxidized azurin [CPD:C05357]

Product

arsenate [CPD:C11215];
reduced azurin [CPD:C05358];
H+ [CPD:C00080]

Comment

Contains a molybdopterin centre comprising two molybdopterin guanosine dinucleotide cofactors bound to molybdenum, a [3Fe-4S] cluster and a Rieske-type [2Fe-2S] cluster. Isolated from beta-proteobacteria. Also uses a c-type cytochrome or O2 as acceptors.

History

EC 1.20.9.1 created 2001 as EC 1.20.98.1, transferred 2011 to EC 1.20.9.1

Orthology

K08355

arsenite oxidase small subunit

K08356

arsenite oxidase large subunit

Genes

VSP:	VS_II0658 VS_II0659

VTA:	A0943 A0944 B1225 B1226

MBS:	MRBBS_1242(aoxB) MRBBS_1243(aoxA)

MPQ:	ABA45_06345

MVS:	MVIS_1833(aoxA)

MYA:	MORIYA_1165 MORIYA_1166

AEH:

Mlg_1558

GAI:	IMCC3135_25220

HSI:	BOX17_13460 BOX17_13465

RSL:	RPSI07_mp0919(aoxA) RPSI07_mp0920(aoxB)

CUH:	BJN34_21510 BJN34_21515

CBW:	RR42_s1794 RR42_s1795

CCUP:

BKK81_17850 BKK81_17855 BKK81_22395

CUU:	BKK79_24695 BKK79_24700

BOC:	BG90_1022 BG90_1023

BVE:	AK36_5595 AK36_5596

BMJ:	BMULJ_05810(asoA) BMULJ_05811(asoB) BMULJ_05832(asoB) BMULJ_05833(asoA)

BMU:	Bmul_5678 Bmul_5679 Bmul_5703 Bmul_5704

BMK:	DM80_6068 DM80_6069 DM80_6143 DM80_6144

PARB:

CJU94_00385 CJU94_00390

PPNO:

DA70_08845 DA70_08850

CABA:

SBC2_73790(aioB) SBC2_73800(aioA)

AXX:	ERS451415_05769(aioB) ERS451415_05770(aioA)

RFR:	Rfer_3084 Rfer_3085

OTK:	C6570_08745 C6570_08750

HPSE:

HPF_13640(aioB)

HYN:	F9K07_29420 F9K07_29425

DRG:	H9K76_03270 H9K76_03275

HAR:	HEAR0478(aoxB) HEAR0479(aoxA)

HEE:	hmeg3_02275 hmeg3_02280

TIN:	Tint_3061 Tint_3062

THI:	THI_3162(aoxB) THI_3163(aoxA)

METR:

BSY238_2675

SULF:

CAP31_08915 CAP31_08920

SPLB:

SFPGR_23330(soxF)

URU:	DSM104443_02691

UPL:	DSM104440_02414

ATW:	C0099_09795 C0099_09800

AZD:	CDA09_11970 CDA09_11975

BEBA:

BWI17_13330

SKU:	Sulku_1032

SULR:

B649_04295

SBA:	Sulba_2413 Sulba_2414

SMUL:

SMUL_3119(aioB) SMUL_3120(aioA)

SHAL:

SHALO_2876 SHALO_2877

SULS:

Sdiek1_1026 Sdiek1_1028

NIS:

NIS_0033

AAK:	AA2016_4246 AA2016_4247

AMIH:

CO731_03145(aioB) CO731_03146(aioA)

SAME:

SAMCFNEI73_pC1772(aioB) SAMCFNEI73_pC1773(aioA)

EAK:	EKH55_4985 EKH55_4986

RHT:	NT26_p10029(aioB) NT26_p10030(aioA)

NHA:	Nham_4426 Nham_4427

BOF:	FQV39_32090 FQV39_32095

XAU:	Xaut_3949 Xaut_3950

SNO:	Snov_1288 Snov_1289

ANC:	GBB76_17085 GBB76_17090

MOC:	BB934_26195 BB934_26200

CHEL:

AL346_18905 AL346_18910

CDQ:	BOQ54_03350 BOQ54_03355

BLAG:

BLTE_10210 BLTE_10220

MSC:	BN69_1400(aoxB) BN69_1401

MROS:

EHO51_05095 EHO51_05100

NOH:	G5V57_02085 G5V57_02090

PSF:	PSE_5043 PSE_5044

LABP:

FJ695_09860 FJ695_09865

CSE:	Cseg_2507 Cseg_2508

RLI:	RLO149_c022030(aoxA) RLO149_c022040(aoxB)

CON:	TQ29_15470 TQ29_15475

HAT:	RC74_20735

DAA:	AKL17_1594 AKL17_1595

SPSE:

SULPSESMR1_00155(aioA) SULPSESMR1_00156(aioB)

AHT:	ANTHELSMS3_01774(aioA) ANTHELSMS3_01775(aioB)

THAA:

CFI11_15005 CFI11_15010

TGL:	HFZ77_15760 HFZ77_15765

PAMO:

BAR1_01585 BAR1_01590

PGV:	SL003B_2333 SL003B_2334

AMV:	ACMV_26640 ACMV_26650 ACMV_P2_00160 ACMV_P2_00170

BACI:

B1NLA3E_03580

GST:	HW35_13485

BACQ:

DOE78_14710

BCO:	Bcell_2932

BCOH:

BC6307_03535

BON:	A361_18050

VIR:	X953_02020

VHL:	BME96_01380

BSJ:	UP17_09935

PBUT:

DTO10_23785

POF:	GS400_18185

NMK:	CHR53_05940

MEKU:

HUW50_24820

AIA:	AWH56_015545

EAT:	EAT1b_1905

BBE:	BBR47_47180

BLR:	BRLA_c027090

BFM:	BP422_19300

BRW:	GOP56_06075

PMS:	KNP414_01413

PMQ:	PM3016_1730

PMW:

B2K_08810

CAU:	Caur_1209 Caur_1210

CHL:	Chy400_1322 Chy400_1323

CAG:	Cagg_0377 Cagg_0378

TTR:

Tter_2537

DGE:

Dgeo_1251

DDR:	Deide_08260

DMR:	Deima_1145

DPT:	Deipr_0889

DPD:	Deipe_0804

DSW:	QR90_01820

DCH:	SY84_03750

DAB:	AUC44_05220

DPU:	SU48_09115

DFC:

DFI_03960

DEIN:

DAAJ005_03325

DGA:	DEGR_20740

TRA:

Trad_0410

TTJ:	TTHB127 TTHB128

TTS:	Ththe16_2239 Ththe16_2240

TSC:	TSC_c14680(aoxB) TSC_c14700(aoxA)

TAQ:	TO73_0834 TO73_0835

TBC:	A0O31_02546 A0O31_02547

MRB:

Mrub_2869

MRE:	K649_08180

PND:	Pla175_21920(aioB)

SUS:

Acid_2926

PFER:

IRI77_14250

ABAC:

LuPra_00131(aioB)

CPB:	Cphamn1_2364 Cphamn1_2365

CLI:	Clim_0382 Clim_0383

HHO:	HydHO_0313 HydHO_0314

HYS:	HydSN_0324 HydSN_0325

TRD:	THERU_04625 THERU_04630

NDE:	NIDE3704(aoxA) NIDE3705(aoxB)

HALB:

EKH57_17170 EKH57_17175

HLC:	CHINAEXTREME13385 CHINAEXTREME13390

APE:	APE_2556.1 APE_2563

ACJ:	ACAM_1597 ACAM_1598

STO:	STK_23910 STK_23920

SOH:	D1869_13100 D1869_13105

SULA:

BFU36_12340 BFU36_12370

MCN:	Mcup_1604 Mcup_1611

MHK:	DFR87_05070 DFR87_05105

MTEN:

GWK48_00020 GWK48_11320

AHO:	Ahos_1882 Ahos_1883

AMAN:

B6F84_04000 B6F84_04010

ABRI:

DFR85_00200 DFR85_00205 DFR85_00260

ASUL:

DFR86_03900 DFR86_03910

STEP:

IC006_2112 IC006_2120

PCL:	Pcal_1369 Pcal_1370

PYR:	P186_1845 P186_1846

POG:	Pogu_0531 Pogu_0532

» show all

Reference

1 [PMID:1331097]

Authors

Anderson GL, Williams J, Hille R

Title

The purification and characterization of arsenite oxidase from Alcaligenes faecalis, a molybdenum-containing hydroxylase.

Journal

J Biol Chem 267:23674-82 (1992)

Sequence

[ag:AAQ19838 AAQ19839]

Reference

2 [PMID:11250197]

Authors

Ellis PJ, Conrads T, Hille R, Kuhn P

Title

Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A.

Journal

Structure 9:125-32 (2001)
DOI:10.1016/S0969-2126(01)00566-4

Sequence

[ag:AAQ19838 AAQ19839]

Other DBs

ExplorEnz - The Enzyme Database:

1.20.9.1

IUBMB Enzyme Nomenclature:

1.20.9.1

ExPASy - ENZYME nomenclature database:

1.20.9.1

UM-BBD (Biocatalysis/Biodegradation Database):

1.20.9.1

BRENDA, the Enzyme Database:

1.20.9.1

CAS:	146907-46-2

DBGET integrated database retrieval system