KEGG   ENZYME: 1.3.1.124
Entry
EC 1.3.1.124                Enzyme                                 
Name
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing];
SPS19 (gene name);
DECR1 (gene name);
DECR2 (gene name);
Delta2,Delta4-dienoyl-CoA reductase (ambiguous)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(3E)-3-enoyl-CoA:NADP+ 4-oxidoreductase
Reaction(IUBMB)
(1) a (3E)-3-enoyl-CoA + NADP+ = a (2E,4E)-2,4-dienoyl-CoA + NADPH + H+ [RN:R12629];
(2) a (3E)-3-enoyl-CoA + NADP+ = a (2E,4Z)-2,4-dienoyl-CoA + NADPH + H+ [RN:R12630]
Reaction(KEGG)
R12629 R12630
Substrate
(3E)-3-enoyl-CoA [CPD:C05067];
NADP+ [CPD:C00006]
Product
(2E,4E)-2,4-dienoyl-CoA [CPD:C04512];
NADPH [CPD:C00005];
H+ [CPD:C00080];
(2E,4Z)-2,4-dienoyl-CoA [CPD:C22258]
Comment
This enzyme, characterized from eukaryotic organisms, catalyses the reduction of either (2E,4E)-2,4-dienoyl-CoA or (2E,4Z)-2,4-dienoyl-CoA to (3E)-3-enoyl-CoA. The best substrates for the enzyme from bovine liver have a chain-length of 8 or 10 carbons. Mammals possess both mitochondrial and peroxisomal variants of this enzyme. cf. EC 1.3.1.34, 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing].
History
EC 1.3.1.124 created 2020
Orthology
K13236  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial
K13237  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], peroxisomal
Genes
HSA: 1666(DECR1) 26063(DECR2)
PTR: 112204143(DECR2) 736777(DECR1)
PPS: 100985245(DECR1) 100989760(DECR2)
GGO: 101126321(DECR1) 101152371(DECR2)
PON: 100172330(DECR2) 100448925(DECR1)
PPYG: 129016177(DECR2) 129042422(DECR1)
NLE: 100585734(DECR1) 100585845(DECR2)
HMH: 116462327(DECR2) 116813399(DECR1)
SSYN: 129462321(DECR2) 129486589(DECR1)
MCC: 695540(DECR2) 696035(DECR1)
MCF: 102144225(DECR1) 102145768(DECR2)
MTHB: 126944860 126961843
MNI: 105485914(DECR2) 105497282(DECR1)
CSAB: 103225407(DECR2) 103237099(DECR1)
CATY: 105572964(DECR1) 105574485(DECR2)
PANU: 100137284(DECR2) 101007820(DECR1)
TGE: 112614183(DECR2) 112629871(DECR1)
MLEU: 105541548(DECR1)
RRO: 104654648(DECR1) 104676958(DECR2)
RBB: 108521129(DECR2) 108526907(DECR1)
TFN: 117079485(DECR1) 117097911(DECR2)
PTEH: 111524040(DECR2) 111549665(DECR1)
CANG: 105508237(DECR1) 105524713(DECR2)
CJC: 100393816(DECR2) 100400830(DECR1)
SBQ: 101032159(DECR1) 101050434(DECR2)
CIMI: 108290857(DECR2) 108310874(DECR1)
ANAN: 105725880(DECR1) 105728383(DECR2)
CSYR: 103249919(DECR2) 103262893(DECR1)
MMUR: 105856269(DECR2) 105870550(DECR1)
LCAT: 123631387(DECR2) 123644458(DECR1)
PCOQ: 105809780(DECR1) 105822609(DECR2)
OGA: 100963146(DECR1) 100966778(DECR2)
MMU: 26378(Decr2) 67460(Decr1)
MCAL: 110284239(Decr2) 110293087(Decr1)
MPAH: 110338200(Decr2) 110338860(Decr1)
RNO: 117543(Decr1) 64461(Decr2)
MCOC: 116078584(Decr2) 116088046(Decr1)
ANU: 117698490(Decr1) 117711546(Decr2)
ASYL: 127680570(Decr1) 127694973(Decr2)
MUN: 110545064(Decr1) 110548715(Decr2)
CGE: 100753128(Decr1) 100759323(Decr2)
MAUA: 101825296(Decr1) 101829464(Decr2)
PROB: 127219483(Decr2) 127229279 127232482(Decr1)
PLEU: 114681238(Decr2) 114694598(Decr1)
MORG: 121451660(Decr1) 121463789(Decr2)
MFOT: 126496936 126515719
AAMP: 119811929(Decr2) 119825930(Decr1)
NGI: 103729535(Decr1) 103752377(Decr2)
HGL: 101720323(Decr2) 101721782(Decr1)
CPOC: 100713979(Decr2) 100715286(Decr1)
CCAN: 109681383 109690121(Decr1) 109694652(Decr2)
DORD: 105981793(Decr2) 105982743(Decr1)
DSP: 122098156(Decr2) 122102455(Decr1)
PLOP: 125340748(Decr2) 125360716(Decr1)
NCAR: 124986868
MMMA: 107142489(Decr1) 107146786(Decr2)
ITI: 101955888(Decr1) 101977822(Decr2)
OCU: 100348851 100352241 103347237
OPI: 101522993(DECR1) 101534172(DECR2)
TUP: 102471220(DECR2) 102475445(DECR1) 102492775
GVR: 103595719(DECR2) 103601773(DECR1)
CFA: 100688128(DECR2) 477938(DECR1)
CLUD: 112640634(DECR2) 112650713(DECR1)
VVP: 112909058(DECR2) 112914054 112930908(DECR1)
VLG: 121486921(DECR2) 121498775(DECR1)
NPO: 129495665(DECR1) 129519392(DECR2)
AML: 100473271(DECR2) 100481266(DECR1)
UMR: 103661415(DECR1) 103668732(DECR2)
UAH: 113245374(DECR2) 113252959(DECR1)
UAR: 123783323(DECR2) 123797901(DECR1)
ELK: 111146553 111156214
LLV: 125090917 125097967
MPUF: 101687475(DECR1) 101694106(DECR2)
MNP: 132014145(DECR1) 132027094(DECR2)
MLK: 131819232(DECR2) 131826624(DECR1)
NVS: 122895672(DECR2) 122904457(DECR1)
ORO: 101375736(DECR1) 101376230(DECR2)
EJU: 114213514(DECR1) 114215739(DECR2)
ZCA: 113911506(DECR1) 113933677(DECR2)
MLX: 118014999(DECR1) 118021655(DECR2)
NSU: 110578683(DECR1) 110588063(DECR2) 110588256
LWW: 102733951(DECR2) 102748446
FCA: 101087299(DECR1) 101088540(DECR2)
PYU: 121019786(DECR2) 121042674(DECR1)
PCOO: 112859313(DECR1) 112860147(DECR2)
PBG: 122471929(DECR2) 122495574(DECR1)
PVIV: 125154556(DECR2) 125156336(DECR1)
LRUF: 124519048 124525510
LGF: 123585824(DECR1) 123589130(DECR2)
AJU: 106977360 106984789
PTG: 102950586(DECR1) 102970768(DECR2)
PPAD: 109259629(DECR2) 109269462(DECR1)
PUC: 125924807 125928391
PLEZ: 122209915(DECR2) 122210999(DECR1)
HHV: 120225181(DECR2) 120237333(DECR1)
BTA: 509952(DECR1) 768256(DECR2)
BOM: 102276962(DECR1)
BIU: 109568554(DECR1) 109578698(DECR2)
BBUB: 102392805(DECR2) 102404940(DECR1)
BBIS: 104989253(DECR2) 105004464(DECR1)
CHX: 102186732(DECR2) 102191818(DECR1)
OAS: 101110109(DECR2) 101115040(DECR1)
BTAX: 128059344(DECR1) 128070466(DECR2)
CSUM: 138075678(DECR2) 138088387(DECR1)
ODA: 120854962(DECR2) 120878512(DECR1)
CCAD: 122433489(DECR2) 122451123(DECR1)
MREE: 136145039(DECR1) 136160372(DECR2)
OVR: 110122497(DECR1) 110141327(DECR2)
MBEZ: 129545187(DECR2) 129560449(DECR1)
SSC: 100524368(DECR2) 503544(DECR1)
CFR: 102506320(DECR1) 102522579(DECR2)
CBAI: 105064733(DECR1) 105065733(DECR2)
CDK: 105087539(DECR1) 105098427(DECR2)
VPC: 102528749(DECR1) 102533908(DECR2)
BACU: 103003311(DECR2) 103018125(DECR1)
BMUS: 118881277(DECR2) 118883530(DECR1)
LVE: 103083575(DECR2) 103090523(DECR1)
OOR: 101271181(DECR2) 101276216(DECR1)
LALB: 132506494(DECR2) 132508062(DECR1)
DLE: 111180437(DECR1) 111185099(DECR2)
PCAD: 102982907(DECR1) 102984684(DECR2)
PSIU: 116740309(DECR2) 116742479(DECR1)
NASI: 112406864(DECR1) 112409489(DECR2)
ECB: 100053423(DECR1) 100065146(DECR2)
EPZ: 103562923(DECR1) 103564116(DECR2)
EAI: 106836165(DECR2) 106838975(DECR1)
MYB: 102239975(DECR1) 102249531(DECR2)
MYD: 102760553(DECR2) 102770411(DECR1)
MMYO: 118652899(DECR2) 118670476(DECR1)
MLF: 102419764(DECR2) 102433528(DECR1)
MDT: 132220157(DECR1) 132232844(DECR2)
MYUM: 138992940(DECR1) 139009236(DECR2)
PKL: 118718484(DECR1) 118731497(DECR2)
EFUS: 103300769(DECR2) 103301865(DECR1)
MNA: 107526478(DECR1) 107545463(DECR2)
DRO: 112298258(DECR2) 112310308(DECR1)
SHON: 118978854(DECR2) 118989287(DECR1)
AJM: 119058255(DECR2) 119060054(DECR1)
PDIC: 114498841(DECR2) 114501393(DECR1)
PHAS: 123820976(DECR1) 123825700(DECR2)
MMF: 118631588(DECR1) 118642269(DECR2)
PPAM: 129081251(DECR2) 129088207(DECR1)
HAI: 109385940(DECR2) 109387599(DECR1)
RFQ: 117019549(DECR2) 117033657(DECR1)
PALE: 102877745(DECR2) 102882014(DECR1)
PGIG: 120614248(DECR1) 120620168(DECR2)
PVP: 105303255(DECR2) 105304149(DECR1)
RAY: 107506135(DECR2) 107507471(DECR1)
MJV: 108384590(DECR2) 108394802(DECR1)
TOD: 119239919(DECR1) 119242067(DECR2)
SARA: 101547921(DECR1) 101550833(DECR2)
SFUM: 130021777(DECR1) 130042919(DECR2)
SETR: 126000837(DECR2) 126020626(DECR1)
LAV: 100664822(DECR1) 100676256(DECR2)
TMU: 101346627 101361590
ETF: 101649088(DECR2) 101658933(DECR1)
DNM: 101416215 101420796(DECR1)
MDO: 100020025(DECR2) 100029422(DECR1)
GAS: 123230944(DECR2) 123240661(DECR1)
SHR: 100915519(DECR1) 100924629(DECR2)
AFZ: 127542961 127544271
PCW: 110203269(DECR1) 110221885(DECR2)
TVP: 118830754(DECR2) 118848926(DECR1)
PBRV: 138160138(DECR1) 138176959(DECR2)
OAA: 100076917(DECR1) 100078257(DECR2)
TACU: 119927235(DECR1) 119942668(DECR2) 119942706
GGA: 100858408(DECR2) 420218(DECR1)
PCOC: 116227594(DECR1) 116230281(DECR2)
MGP: 100542270(DECR1) 100544413(DECR2)
CJO: 107310389(DECR1) 107320900(DECR2)
TPAI: 128079102(DECR2) 128090778(DECR1)
LMUT: 125690400(DECR1) 125700835(DECR2)
NMEL: 110394082(DECR1) 110405763(DECR2)
APLA: 101794432(DECR2) 101800525(DECR1)
ACYG: 106030535(DECR1) 106033348(DECR2)
CATA: 118247869(DECR1) 118249330(DECR2)
AFUL: 116486571(DECR1) 116495142(DECR2)
TGU: 100190086(DECR1) 100223602(DECR2)
LSR: 110477426(DECR1) 110482682(DECR2)
SCAN: 103813424(DECR1) 103817937(DECR2)
PMOA: 120495776(DECR1) 120512925(DECR2)
OTC: 121337048(DECR2) 121340147(DECR1)
PRUF: 121350660(DECR2) 121351931(DECR1)
ATRC: 139587367(DECR1) 139598298(DECR2)
GFR: 102031386(DECR1) 102041641(DECR2)
FAB: 101810228(DECR1) 101811791(DECR2)
OMA: 130250335(DECR1) 130259111(DECR2)
PHI: 102099571(DECR2) 102100338(DECR1)
PMAJ: 107199912(DECR1) 107211421(DECR2)
CCAE: 111924567(DECR1) 111936243(DECR2)
CCW: 104684942(DECR2) 104692760(DECR1)
CBRC: 103613444(DECR1) 103620502(DECR2)
ACOE: 138105290(DECR1) 138118754(DECR2)
ETL: 114061737(DECR1) 114067200(DECR2)
ZAB: 102065553(DECR1) 106630072(DECR2)
ZLE: 135444607(DECR1) 135454240(DECR2)
ACHL: 103806663(DECR2) 103810708(DECR1)
SVG: 106849865(DECR1) 106860589(DECR2)
MMEA: 130576425(DECR1) 130577233(DECR2)
HRT: 120752652(DECR1) 120759561(DECR2)
SATI: 136368088(DECR2) 136370066(DECR1)
CCIC: 134042555(DECR1) 134050505(DECR2)
FPG: 101919053(DECR2) 101923272(DECR1)
FCH: 102049751(DECR2) 102056124(DECR1)
CCRI: 104156295(DECR2) 104159659(DECR1)
NNT: 104399987(DECR1) 104408270(DECR2)
SHAB: 115604855(DECR1) 115606350(DECR2)
ACUN: 113476727(DECR1) 113485712(DECR2)
TALA: 104361179(DECR1) 104368635(DECR2)
ACHC: 115335725(DECR2) 115340118(DECR1)
HALD: 104315750(DECR2) 104319085(DECR1)
HLE: 104828366(DECR1) 104831437(DECR2)
AGEN: 126034307 126046654
HHAR: 128134769(DECR2) 128141794(DECR1)
GCL: 127013452 127022476
CSTI: 104549248(DECR1) 104559386(DECR2)
LDI: 104346271(DECR1) 104353132(DECR2)
MNB: 103771710(DECR2) 103773157(DECR1)
DPUB: 104297224(DECR1) 104300437(DECR2)
PPUS: 135180636(DECR2) 135181390(DECR1)
AVIT: 104273004(DECR1) 104281247(DECR2)
BRHI: 104500372(DECR1)
EGZ: 104125807(DECR1) 104127269(DECR2)
NNI: 104016406(DECR1) 104023473(DECR2)
PCRI: 104023791(DECR1) 104024455(DECR2)
PCAO: 104049126(DECR2) 104053037(DECR1)
PADL: 103912560(DECR2) 103917311(DECR1)
AFOR: 103895791(DECR1) 103898262(DECR2)
FGA: 104078321(DECR1) 104081819(DECR2)
GSTE: 104257421(DECR1) 104263349(DECR2)
CLV: 102091063(DECR1) 102098896(DECR2)
MUI: 104537290(DECR2) 104548870(DECR1)
PGUU: 104458783(DECR1) 104466334(DECR2)
PLET: 104615075(DECR1) 104627605(DECR2)
EHS: 104504647(DECR2) 104512991(DECR1)
CMAC: 104478852(DECR2) 104483410(DECR1)
CUCA: 104056794(DECR1) 128853710(DECR2)
TEO: 104372463(DECR1) 104384134(DECR2)
BREG: 104634918(DECR2) 104639054(DECR1)
OHA: 104336091(DECR2) 104337579(DECR1)
ACAR: 104518570(DECR1) 104522415(DECR2)
CPEA: 104393352(DECR2) 104396639(DECR1)
CVF: 104283754(DECR2) 104292468(DECR1)
RTD: 128905466(DECR1) 128913468(DECR2)
AAM: 106496198(DECR1) 106500017(DECR2)
AROW: 112964076(DECR1) 112965875(DECR2)
NPD: 112955670(DECR2) 112960311(DECR1)
TGT: 104572495(DECR1) 104577897(DECR2)
DNE: 112983011(DECR1) 112986908(DECR2)
SCAM: 104143416(DECR2) 104143957(DECR1)
ASN: 102367904(DECR2) 102380885(DECR1)
AMJ: 102565758(DECR2) 102571942(DECR1)
CPOO: 109313424(DECR2) 109320262(DECR1)
GGN: 109287156(DECR2) 109305025(DECR1)
PSS: 102453305(DECR2)
CMY: 102929590(DECR1) 102939334(DECR2)
CCAY: 125632640(DECR1) 125643504(DECR2)
DCC: 119851809(DECR1) 119862482(DECR2)
CPIC: 101933439(DECR1) 101947023(DECR2)
TST: 117873644(DECR1) 117884008(DECR2)
CABI: 116833650(DECR1) 116836023(DECR2)
MRV: 120373171(DECR2) 120396998(DECR1)
ACS: 100561525(decr2) 100568104(decr1)
ASAO: 132774970(DECR1) 132781783(DECR2)
PVT: 110089491(DECR2) 110090231(DECR1)
SUND: 121914808(DECR2) 121929444(DECR1)
PBI: 103053170(DECR1) 103053628(DECR2)
PMUR: 107285746(DECR1) 107290316(DECR2)
CTIG: 120309460(DECR1) 120310929(DECR2)
TSR: 106540583(DECR2)
PGUT: 117668489(DECR1) 117673137(DECR2)
APRI: 131184968(DECR2) 131195838(DECR1)
PTEX: 113438681(DECR2) 113439922(DECR1)
NSS: 113420718(DECR2) 113428499(DECR1)
VKO: 123020321(DECR1) 123025212(DECR2)
PMUA: 114584421(DECR2) 114600444(DECR1)
PRAF: 128401602(DECR2) 128417271(DECR1)
ZVI: 118090362(DECR1) 118092971(DECR2)
HCG: 128323212(DECR1) 128336312(DECR2)
GJA: 107105991(DECR1) 107126196(DECR2)
STOW: 125431812(DECR2) 125439147(DECR1)
EMC: 129333745(DECR1) 129340590(DECR2)
XLA: 100137679(decr1.L) 443792(decr2.L)
XTR: 394884(decr2) 447965(decr1)
NPR: 108790945(DECR2) 108804496(DECR1)
RTEM: 120941285(DECR1) 120943319(DECR2)
BBUF: 121001490(DECR1) 121008465(DECR2)
BGAR: 122938690(DECR1) 122945128(DECR2)
PWL: 138261418(DECR2) 138282650(DECR1)
MUO: 115475779(DECR2) 115478773(DECR1)
GSH: 117345749(DECR2) 117355210(DECR1)
DRE: 406623(decr2) 436717(decr1)
SRX: 107705494 107717880(decr2) 107756153
SANH: 107667207 107677236 107700707 107704989
SGH: 107556675(decr2) 107588511 107588514
CCAR: 109106610 109112190 109112195(decr2)
CAUA: 113042076 113042129 113059552 113092806
CGIB: 127945898 128012841 128030486
PTET: 122329639(decr2) 122359900(decr1) 122359931
LROH: 127156163(decr2) 127179096(decr1)
OMC: 131521233(decr1) 131533261(decr2)
PPRM: 120479779(decr2) 120484515(decr1)
RKG: 130103335(decr2) 130104393(decr1)
MAMB: 125243130(decr1) 125258505(decr2)
CIDE: 127497416 127506240
CERY: 137014016(decr2) 137033072(decr1)
MASI: 127431580 127434138 127453399 127454002
TROS: 130547410(decr2) 130557638(decr1)
TDW: 130413596(decr2) 130433297(decr1)
MANU: 129425939(decr2) 129448361(decr1)
PDAB: 135740428(decr2) 135788964(decr1)
IPU: 108264653 108270672
IFU: 128605332(decr2) 128613264(decr1)
PHYP: 113526897(decr1) 113533695(decr2)
SMEO: 124384942(decr1) 124384948(decr2)
TFD: 113644660(decr1) 113663707(decr2)
TVC: 132845664(decr1) 132846446(decr2)
CGAR: 128520137(decr1) 128520442(decr2)
NGRA: 132886122(decr1) 132886486(decr2)
TRN: 134309883(decr1) 134310908(decr2)
AMEX: 103033958(decr2) 103034261(decr1)
CMAO: 118800365(decr1) 118822069(decr2)
EEE: 113572222(decr1) 113586569(decr2)
CHAR: 105896160(decr1) 105903306(decr2)
SPIL: 134070273(decr2) 134082620(decr1)
TRU: 101075792(decr2) 101076267(decr1)
TFS: 130525595(decr2) 130532124(decr1)
TNG: GSTEN00011542G001 GSTEN00024053G001
LCO: 104919685(decr2) 104937307(decr1)
NCC: 104946354(decr2)
TBEN: 117469470(decr1) 117473654(decr2)
CGOB: 115024610(decr2)
PGEO: 117442598(decr1) 117464823(decr2)
GACU: 117545098(decr2)
EMAC: 134863341(decr1) 134870385(decr2)
ELY: 117246739(decr2) 117265949(decr1)
EFO: 125881232(decr2) 125892961(decr1)
PLEP: 121937690(decr1) 121958915(decr2)
SLUC: 116044255(decr2) 116058490(decr1)
ECRA: 117937453(decr2) 117940578(decr1)
ESP: 116671808(decr2)
PFLV: 114548258(decr2) 114557403(decr1)
GAT: 120811158(decr1) 120819325(decr2)
PPUG: 119197560(decr1) 119212674(decr2)
AFB: 129091462(decr2) 129109646(decr1)
CLUM: 117745858(decr1) 117748672(decr2)
PSWI: 130203395(decr2) 130213178(decr1)
CANA: 137781252(decr1) 137789497(decr2)
CVE: 137887159(decr1)
MSAM: 119884270 119892986 119916185(decr2)
SCHU: 122867584(decr2) 122881703(decr1)
CUD: 121514327(decr1) 121527972(decr2)
SPUL: 138593836(decr2) 138606727(decr1)
LMIX: 132955437(decr2) 132983227(decr1)
ALAT: 119006481(decr1) 119009419(decr2)
ASTR: 137588475(decr2) 137600954(decr1)
MZE: 101470346(decr2) 101484990(decr1)
ONL: 100699352(decr2) 100709209(decr1)
OAU: 116319921(decr2) 116334898(decr1)
OLA: 101162249(decr2) 101168931(decr1)
OML: 112139359(decr1) 112154585(decr2)
CSAI: 133418950(decr2) 133424892(decr1)
XMA: 102231692(decr2) 102237059(decr1)
XCO: 114140124(decr1) 114149662(decr2)
XHE: 116717891(decr1) 116726581(decr2)
PRET: 103477451(decr1) 103481087(decr2)
PFOR: 103131141(decr1) 103156078(decr2)
PLAI: 106940010(decr1) 106947556(decr2)
PMEI: 106929864(decr2) 106932705(decr1)
GAF: 122823501(decr2) 122830907(decr1)
PPRL: 129351017 129355851 129377621(decr2)
CVG: 107084994(decr2) 107095266(decr1)
CTUL: 119780902(decr1) 119793694(decr2)
GMU: 124865330(decr1) 124874740(decr2)
NFU: 107379237(decr1) 107388057(decr2)
KMR: 108228469(decr1) 108237227(decr2)
ALIM: 106517386(decr2) 106536744(decr1)
NWH: 119409589(decr1) 119423438(decr2)
AOCE: 111569477(decr1) 111579698(decr2)
EJA: 138202076(decr2) 138214456(decr1)
BFRE: 138616910(decr2) 138633793(decr1)
MCEP: 125022146(decr2)
CSEM: 103381689(decr2) 103388041(decr1)
POV: 109623758 109626917(decr2) 109645468
SSEN: 122758843(decr2) 122774100(decr1)
HHIP: 117753122(decr2)
HSP: 118100587(decr2) 118113436(decr1)
PPLT: 128426680(decr2) 128449206(decr1)
SMAU: 118284560(decr1) 118287045(decr2)
LCF: 108884700 108886783
SDU: 111220127(decr2) 111234085(decr1)
SLAL: 111649954(decr1) 111658619(decr2)
XGL: 120784411(decr1) 120794747(decr2)
HCQ: 109512151(decr1) 109526513(decr2)
SSCV: 125974878(decr1) 125991738(decr2)
SBIA: 133495170(decr2) 133513674(decr1)
PEE: 133413226(decr1) 133417854(decr2)
PTAO: 133469230(decr2) 133487423(decr1)
BPEC: 110159721(decr2) 110172361(decr1)
MALB: 109963511(decr2) 109970890(decr1)
BSPL: 114842728(decr1) 114845733(decr2)
SJO: 128367051(decr1) 128381921(decr2)
SSCO: 133983106(decr1) 134003068(decr2)
GMH: 115531019(decr2) 115554331(decr1)
SASA: 106580438 106605467(decr1)
STRU: 115159799(decr2) 115179715
OTW: 112222869 112223710(decr2)
OMY: 110486585(decr1) 110491617(decr2)
OGO: 123997805(decr1) 124047608(decr2)
ONE: 115103289 115106188(decr2) 115141000
OKI: 109865927(decr2) 109901961
OKE: 118364507(decr1) 118365921(decr2)
OMM: 135504904(decr2) 135522184(decr1)
SALP: 111950544 111965036(decr1) 111978551(decr2)
SNH: 120031643 120045497(decr2) 120048458(decr1)
CCLU: 121567366(decr2) 121570301 121572412
ELS: 105019171(decr1) 105021269(decr2)
SFM: 108923861(decr2) 108940513(decr1)
PKI: 111841908(decr2) 111860660(decr1)
AANG: 118212784(decr1) 118217349(decr2)
AROT: 135248094(decr2) 135256857(decr1)
CCOG: 133121690(decr2) 133135328 133141382
LOC: 102687852(decr2) 102691826(decr1)
PSPA: 121301046(decr2) 121314994(decr1)
ARUT: 117431304(decr2) 117435439(decr1)
PSEX: 120515555(decr1) 120542275(decr2)
LCM: 102356436(DECR1) 102366665(DECR2)
CMK: 103178764(decr2) 103184930(decr1)
RTP: 109913573 109932331(decr2)
CPLA: 122549009(decr1) 122560650(decr2)
HOC: 132815458(decr1) 132825186(decr2)
LERI: 129696131(decr1) 129706880(decr2)
PMRN: 116949615(DECR2) 116954238(DECR1)
LRJ: 133346952(DECR2) 133347304 133355761 133355984
BFO: 118417612 118429724
BBEL: 109462821 109473564
CIN: 100180648 100185689
SCLV: 120326758 120342156 120343108
SPU: 588523 589146 590477 763456
LPIC: 129254267 129254268 129269192 129269917 129280007
APLC: 110980338 110980385 110980398 110982170
ARUN: 117289057 117292242
AJC: 117110195 117123054
SKO: 100368583 100379042
PFLL: 139148078 139151502
BCOO: 119066676
FCD: 110843971 110853998
DPX: DAPPUDRAFT_305017
DMK: 116917892
DPZ: 124315024
AFRA: 136041427
PVM: 113816958
PJA: 122257636
PCHN: 125041762
PMOO: 119581889
HAME: 121863235
PCLA: 123775311
CQD: 128705316
PTRU: 123511463
ESN: 126980956
MNZ: 135217285
MRJ: 136835677
PORN: 139748643
HAZT: 108674833
EAF: 111706449
TCF: 131885367
PPOI: 119099366
DSV: 119444718 119445674
RSAN: 119390804 119390810
RMP: 119170719 119182208
VDE: 111247167
VJA: 111273806
CSCU: 111633074
CVS: 136985936
LPOL: 106474967
CEL: CELE_F53C11.3(decr-1.1) CELE_T05C12.3(decr-1.3) CELE_W01C9.4(decr-1.2)
CBR: CBG_00572(Cbr-decr-1.3) CBG_11484
CRQ: GCK72_004945
NAI: NECAME_10436
HRO: HELRODRAFT_187537
LGI: LOTGIDRAFT_213936 LOTGIDRAFT_229651
PVUL: 126811702 126816103
PCAN: 112563050 112576860
LSAX: 138958389 138972634
BGT: 106053809 106063822
GAE: 121379840 121388688
HRF: 124132560 124137563
HRJ: 124279566 124284549
HASI: 137257611 137283608
HCRA: 139446709 139468707
CRG: 105324316 105342001
CANU: 128164683 128186955
CVN: 111122122 111134852
OED: 125668442 125680859
MYI: 110441650 110448587 110448641
PMAX: 117332856 117337164
AIRR: 138315921 138323605
MCAF: 127700912 127707736
MMER: 123548816 123565071
RPHI: 132737925 132750410
DPOL: 127844933 127865755
MAEA: 128211982 128222643 128242298 128242321
OBI: 106873880 106883385
OSN: 115214067 115221495
LJP: 135475799 135476803
LAK: 106155259 106176835
OVI: T265_01692
LLON: 135495787 135498464
NVE: 5499755 5502416 5504216 5506878
EPA: 110232461 110237641
ATEN: 116297860 116302373
ADF: 107332695 107336221 107352209
AMIL: 114958158 114968880
MCAZ: 138021706 138059281
MFOO: 137970815 137990990
PDAM: 113673646 113685316
SPIS: 111336265
DGT: 114517200
XEN: 124436555
HMG: 100208057
HSY: 130614052
RES: 135690513 135690931
TAD: TRIADDRAFT_31628 TRIADDRAFT_63390
AQU: 100636990 100641010
ATH: AT2G07640 AT3G12800(SDRB)
ALY: 9320993
CRB: 17890996
CSAT: 104745501 104765047 104772309 104777002
EUS: EUTSA_v10021233mg
BRP: 103859468 103870224
BNA: 106353105 106389842 106400716 106452364
BOE: 106328417 106343258
RSZ: 108856424 108856608 130495182
THJ: 104826329
CPAP: 110817285 110817384
CIT: 102615558 102627054
CIC: CICLE_v10005524mg CICLE_v10016100mg
PVY: 116137055
MINC: 123197975
TCC: 18594888 18607039
GRA: 105763066 105766230 105792781
GHI: 107909155 107928399 107928733 107945225 107947876
GAB: 108452465 108467898 108478611
HSYR: 120143813 120144485 120161509 120174092 120197919
DZI: 111283033 111287924 111308529
EGR: 104440625 104451030 120292907
RARG: 115736598 115755427
GMX: 100793630 100800885
GSJ: 114388153 114422642
PVU: 137830716
VRA: 106755217
VAR: 108319077
VUN: 114170705
VUM: 124820565
CCAJ: 109791092
APRC: 113864488
MTR: 25502359
TPRA: 123896675 123896677 123896743 123896744
CAM: 101506957 101507712
PSAT: 127075440 127075441
VVO: 131620305
LJA: 130745181
ADU: 107478393
AIP: 107630070
AHF: 112737912 112790048
LANG: 109339361
PCIN: 129297276 129301388 129315832
QSA: O6P43_001229 O6P43_029379
FVE: 101293375 101306851
AANS: 126785673 126785762
RCN: 112164582 112202202
PPER: 18778155 18778633
PMUM: 103325473 103325732
PAVI: 110746351 110747664 110767357
PDUL: 117624062 117626717
MDM: 103435295 103435392 103445870
MSYL: 126586374 126622182 126624572
PXB: 103933731
PCOX: 137725288 137725734 137729550
ZJU: 107417910 107420848
MNT: 112091285
CSAV: 115709085 115710052
CSV: 101215029
CMO: 103489636
BHJ: 120078067
MCHA: 111016706
CMAX: 111468426
CMOS: 111455238
CPEP: 111776381
RCU: 8260156 8289500
MEAN: 126671680 126682227
JCU: 105641060 105646164
HBR: 110665963
MESC: 110599864 110608081
POP: 7479623 7482193
PEU: 105129532 105136866
PALZ: 118052952 118060618
PNZ: 133678398 133690228
JRE: 108984959 109011254
CILL: 122279668 122281108
CAVE: 132170819 132171552 132175934
AGLU: 133869641 133874795
QSU: 112007613 112035780
QLO: 115987299
TWL: 119987620
VVI: 100248493 100257583
VRI: 117909399 117914133
SLY: 101254404
SPEN: 107025337
SOT: 102605057
SSTN: 125875879
SDUL: 129891657
CANN: 107878931
LBB: 132618419
NTA: 107763475 107782910 107800988
NSY: 104219422
NTO: 104087848 104087849
NAU: 109234111
INI: 109178098
ITR: 116019133
SIND: 105168104 105175095
OEU: 111368230 111395865
EGT: 105962147 105968604
SSPL: 121745555 121755463 121758659 121786331 121791066
SMIL: 130986006 131011412
SHIS: 125187272 125193671 125216932
APAN: 127249608 127253317
HAN: 110895870 110929812 110929814
ECAD: 122580558 122600999
LSV: 111908954 111911099
CCAV: 112499806 112512023
DCR: 108206087 108224824
CSIN: 114261588 114278254
RVL: 131321831
AEW: 130792575
DLT: 127791337 127807811
BVG: 104887053
SOE: 110804428
CQI: 110707556 110739385
ATRI: 130803889
MOF: 131143779 131160595
NNU: 104599664
MING: 122090015
TSS: 122640147 122640148
PSOM: 113287325 113295327 113313499 113323261 113323272 113335451 113342600
OSA: 129493522
DOSA: Os04g0614000
OBR: 102701258
OGL: 127771165
BDI: 100838861
ATS: 109766461
TDC: 119356202 119365360
TAES: 123046447 123054286 123190182
TUA: 125539479
LPER: 127336200
LRD: 124673887 124673888 124674029 124674030
SBI: 8063963 8063964
ZMA: 100194355 103504713
MFLO: 136491426 136491457 136493663 136493718 136497447 136497448 136512808
SITA: 101779665 101780066
SVS: 117864079 117864080
PVIR: 120641762 120641763 120682056 120682057
PHAI: 112898815 112898817
PAUA: 133888615
PDA: 103713168
EGU: 105059878 105059879
MUS: 135605254 135608132
ZOF: 122009986 122016985
DCT: 110096616 110103734 110116176
PEQ: 110022199 110028721
AOF: 109822210 109845167
MSIN: 131221031
ACAK: 137951868 137953789
NCOL: 116244776 116251308
ATR: 18421380
CJF: 131039065 131039067
SMO: SELMODRAFT_146763 SELMODRAFT_178329 SELMODRAFT_271745 SELMODRAFT_57313
PPP: 112272949 112276038
CRE: CHLRE_17g731850v5
VCN: VOLCADRAFT_67136
MNG: MNEG_7336
CSL: COCSUDRAFT_19871
CVR: CHLNCDRAFT_136871
APRO: F751_1204
SCE: YNL202W(SPS19)
SEUB: DI49_4540
SPAO: SPAR_N01210
AGO: AGOS_ABL163W
ERC: Ecym_6446
KLA: KLLA0_D18909g
KMX: KLMA_50587(SPS19)
LTH: KLTH0B07656g
VPO: Kpol_1054p31
ZRO: ZYRO0C10274g
CGR: 2888438(GVI51_H07975)
NCS: NCAS_0G01600(NCAS0G01600)
NDI: NDAI_0F03580(NDAI0F03580)
TPF: TPHA_0O01750(TPHA0O01750)
TBL: TBLA_0B00350(TBLA0B00350)
TGB: HG536_0D00640
TDL: TDEL_0A00890(TDEL0A00890)
KAF: KAFR_0A07740(KAFR0A07740)
KNG: KNAG_0F01080(KNAG0F01080)
ZMK: HG535_0G01180
DHA: DEHA2C02178g DEHA2G22198g
PIC: PICST_45705 PICST_57591
PGU: PGUG_00071 PGUG_01155
SPAA: SPAPADRAFT_141696 SPAPADRAFT_57939
LEL: PVL30_001606(SPS19_1) PVL30_003969(SPS19_2)
LBG: 92207975(LODBEIA_P27790) 92210102(LODBEIA_P49060)
CAL: CAALFM_C102270CA(CaO19.3684) CAALFM_C400830WA(SPS20)
CTP: CTRG_00064 CTRG_04642
COT: CORT_0B07500 CORT_0E01150
CDU: CD36_02120 CD36_40880
CTEN: 18248515(SPS19_1) 18250673(SPS19_2)
CLU: CLUG_01714 CLUG_03177
CLUS: A9F13_12g02167 A9F13_13g01595
CAUR: CJI96_0002629 CJI96_0003150
ASAU: 88171529(PUMCH_000460) 88175621(PUMCH_004561)
PPA: PAS_chr3_0975
PKZ: C5L36_0A11080
BNN: FOA43_003564
BBRX: BRETT_004426
OPA: HPODL_02860
YLI: 2909057(YALI2_C00051g) 2910470(YALI2_D01095g) 2911508(YALI2_E01472g)
SLB: AWJ20_246(SPS19) AWJ20_4294(SPS19)
NCR: NCU07958
NTE: NEUTE1DRAFT120724(NEUTE1DRAFT_120724)
SMP: 10807243(SMAC4_08571)
PAN: PODANSg451
PBEL: QC761_301660(SPS19)
PPSD: QC762_301660(SPS19)
PPSP: QC763_301660(SPS19)
PPSA: QC764_301660(SPS19)
TTT: THITE_2115925
MTM: MYCTH_2299438
CTHR: CTHT_0030520
RTHE: 98125863(VTJ83DRAFT_4700)
MGR: MGG_05138
PPEI: PpBr36_03509
PGRI: PgNI_09625
TMN: UCRPA7_1275
SSCK: SPSK_02618
FGR: FGSG_00407
FPU: FPSE_00069
FPOA: FPOAC1_000427
FVN: FVRRES_00571
FVR: FVEG_00866
FOX: FOXG_00645
NHE: NECHADRAFT_98848
FFC: NCS54_00110400 NCS54_01361200
FKR: NCS57_00108500
FMU: J7337_001127
TRE: TRIREDRAFT_76114
TRR: M419DRAFT_95960
TATV: 25782105(TrAtP1_004464)
TASP: 36615631(TrAFT101_003915)
MAW: 19247508(SPS19)
MAJ: MAA_04291
MBRN: 26240521(SPS19)
PCHM: VFPPC_15099
CMT: CCM_02294
AMUS: LMH87_003916
PLJ: 28887299(PLICBS_002560)
PTKZ: JDV02_001298(SPS19)
VAL: VDBG_06030
VDA: VDAG_03191
CHIG: CH63R_05266 CH63R_11784
CDET: 87942351(CDEST_05848) 87946538(CDEST_10036)
SAPO: SAPIO_CDS3090
ELA: UCREL1_8151
PFY: PFICI_00825
SSL: SS1G_04630
BFU: BCIN_01g07920
MBE: MBM_09949
PSCO: LY89DRAFT_636319
GLZ: GLAREA_11191
ANI: ANIA_07770
AFM: AFUA_5G07470
ACT: ACLA_010730
NFI: NFIA_079800
AOR: AO090701000656
ANG: An15g02860
AFV: AFLA_005173
ALUC: AKAW2_60416A
ACHE: ACHE_21289S
APUU: APUU_71179S APUU_80095A
PCS: N7525_004871
PDP: PDIP_52890
POU: POX_a00313
TMF: EYB26_002233
TRG: TRUGW13939_08192
CIM: CIMG_06119
CPW: 9694984(D8B26_006603)
URE: UREG_04269
ABE: ARB_04033
TVE: TRV_05037
PBL: PAAG_04894
PBN: PADG_02632
AJE: HCAG_02897
BGH: BDBG_04122
PNO: SNOG_16378(SNOG_16377)
PTE: PTT_16264
PTRR: 6347911(PtrM4_128860)
BZE: COCCADRAFT_851
BSC: COCSADRAFT_37351
BOR: COCMIDRAFT_41422
AALT: CC77DRAFT_1015750
ADAC: 96085264(ACET3X_004942)
ARAB: EKO05_0011339
ZTR: MYCGRDRAFT_69507
PFJ: MYCFIDRAFT_163004
FFU: CLAFUR5_06466
CBET: CB0940_08322
BCOM: BAUCODRAFT_392081
NPA: UCRNP2_6972
TML: GSTUM_00004837001
CNE: CNI03790
CNB: CNBH3620
CNG: CNAG_04238
CGI: CGB_H4250C
CDEU: CNBG_2808
CDEP: 91085807(L203_101594)
KMG: 30164156(I203_103558)
KNE: 92181126(IAR55_003868)
TMS: TREMEDRAFT_70655
TASA: A1Q1_00949
CCAC: CcaHIS019_0702800(SPS19)
PPL: POSPLDRAFT_86906
TVS: TRAVEDRAFT_160280
DSQ: DICSQDRAFT_110031
PCO: PHACADRAFT_246120
SHS: STEHIDRAFT_164262
HIR: HETIRDRAFT_127365
PSQ: PUNSTDRAFT_117041
ADL: AURDEDRAFT_112734
FME: FOMMEDRAFT_122494
GTR: GLOTRDRAFT_69683
RSX: RhiXN_03664
LBC: LACBIDRAFT_251259(SPS)
CCI: CC1G_05835
ABP: AGABI1DRAFT115110(AGABI1DRAFT_115110)
ABV: AGABI2DRAFT196138(AGABI2DRAFT_196138)
PCUB: JR316_0011337
MPR: MPER_08115
MRR: Moror_8639
MORE: E1B28_006077
SCM: SCHCO_02641597(SCHCODRAFT_02641597)
CPUT: CONPUDRAFT_111684
SLA: SERLADRAFT_471035
WSE: WALSEDRAFT_37173
WIC: J056_001683
UMA: UMAG_10183
PFP: PFL1_01922
SGRA: EX895_004542
MGL: MGL_1622
MRT: MRET_0717
MSYM: MSY001_2513
PGR: PGTG_13490
PTRC: PtA15_6A358
PSTR: Pst134EA_003059
MLR: MELLADRAFT_41456
RIE: OCT59_021728
ACAN: ACA1_288870
TGO: TGME49_226300
BBES: BESB_060310
TET: TTHERM_00637450
PTM: GSPATT00022482001 GSPATT00036343001
PTI: PHATRDRAFT_11319(DER1)
FCY: FRACYDRAFT_212175
TPS: THAPSDRAFT_35810
AAF: AURANDRAFT_58778
PIF: PITG_13341 PITG_15640
PSOJ: PHYSODRAFT_286541 PHYSODRAFT_502845
BLAC: 94352427(CCR75_008706)
SPAR: SPRG_02815
NGR: NAEGRDRAFT_31570
MSTO: MSTO_20200
 » show all
Reference
1  [PMID:729581]
  Authors
Kunau WH, Dommes P.
  Title
Degradation of unsaturated fatty acids. Identification of intermediates in the degradation of cis-4-decenoly-CoA by extracts of beef-liver mitochondria.
  Journal
Eur J Biochem 91:533-44 (1978)
DOI:10.1111/j.1432-1033.1978.tb12707.x
Reference
2  [PMID:6749495]
  Authors
Dommes V, Luster W, Cvetanovic M, Kunau WH.
  Title
Purification by affinity chromatography of 2,4-dienoyl-CoA reductases from bovine liver and Escherichia coli.
  Journal
Eur J Biochem 125:335-41 (1982)
DOI:10.1111/j.1432-1033.1982.tb06688.x
Reference
3  [PMID:9268358]
  Authors
Gurvitz A, Rottensteiner H, Kilpelainen SH, Hartig A, Hiltunen JK, Binder M, Dawes IW, Hamilton B
  Title
The Saccharomyces cerevisiae peroxisomal 2,4-dienoyl-CoA reductase is encoded by the oleate-inducible gene SPS19.
  Journal
J Biol Chem 272:22140-7 (1997)
DOI:10.1074/jbc.272.35.22140
  Sequence
[hsa:1666] [rno:117543] [sce:YNL202W]
Reference
4  [PMID:10464321]
  Authors
Geisbrecht BV, Liang X, Morrell JC, Schulz H, Gould SJ
  Title
The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase.
  Journal
J Biol Chem 274:25814-20 (1999)
DOI:10.1074/jbc.274.36.25814
  Sequence
[mmu:26378]
Reference
5  [PMID:11514237]
  Authors
De Nys K, Meyhi E, Mannaerts GP, Fransen M, Van Veldhoven PP
  Title
Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase.
  Journal
Biochim Biophys Acta 1533:66-72 (2001)
DOI:10.1016/s1388-1981(01)00141-x
  Sequence
[hsa:26063]
Reference
6  [PMID:15531764]
  Authors
Alphey MS, Yu W, Byres E, Li D, Hunter WN
  Title
Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site.
  Journal
J Biol Chem 280:3068-77 (2005)
DOI:10.1074/jbc.M411069200
  Sequence
[hsa:1666]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.124
IUBMB Enzyme Nomenclature: 1.3.1.124
ExPASy - ENZYME nomenclature database: 1.3.1.124
BRENDA, the Enzyme Database: 1.3.1.124

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