KEGG ENZYME: 1.3.1.13

ENZYME: 1.3.1.13

Entry

EC 1.3.1.13                 Enzyme

Name

prephenate dehydrogenase (NADP+);
prephenate dehydrogenase (ambiguous);
prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase;
prephenate dehydrogenase (NADP)

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

prephenate:NADP+ oxidoreductase (decarboxylating)

Reaction(IUBMB)

prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH [RN:R01730]

Reaction(KEGG)

R01730

Substrate

prephenate [CPD:C00254];
NADP+ [CPD:C00006]

Product

4-hydroxyphenylpyruvate [CPD:C01179];
CO2 [CPD:C00011];
NADPH [CPD:C00005]

History

EC 1.3.1.13 created 1972

Pathway

ec00400

Phenylalanine, tyrosine and tryptophan biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K00211

prephenate dehydrogenase (NADP+)

Genes

SCE:	YBR166C(TYR1)

SEUB:

DI49_1194

SPAO:

SPAR_B02660

AGO:	AGOS_AGR219W

ERC:

Ecym_7090

KLA:	KLLA0_E24729g

KMX:	KLMA_10819(TYR1)

LTH:	KLTH0E13794g

VPO:	Kpol_1048p32

ZRO:	ZYRO0A10384g

CGR:	2891656(GVI51_M05973)

NCS:	NCAS_0B01830(NCAS0B01830)

NDI:	NDAI_0C05850(NDAI0C05850)

TPF:	TPHA_0I01630(TPHA0I01630)

TBL:	TBLA_0E04010(TBLA0E04010)

TGB:	HG536_0A06950

TDL:	TDEL_0A05400(TDEL0A05400)

KAF:	KAFR_0G02120(KAFR0G02120)

KNG:	KNAG_0A03820(KNAG0A03820)

ZMK:	HG535_0H02950

SLUD:

SCDLUD_002068

DHA:	DEHA2G18414g

PIC:	PICST_52223(TYR1)

PGU:	PGUG_02400

SPAA:

SPAPADRAFT_58638

LEL:	PVL30_003943(TYR1)

LBG:	92210074(LODBEIA_P48780)

CAL:	CAALFM_C401880WA(TYR1)

CTP:	CTRG_00228

COT:	CORT_0E00770

CDU:	CD36_41770

CTEN:

18247562(TYR1)

CLU:	CLUG_05025

CLUS:

A9F13_03g02068

CAUR:

CJI96_0001252

PPA:	PAS_chr2-2_0317

PKZ:	C5L36_0B09140

BNN:	FOA43_001848(TYR1)

BBRX:

BRETT_004663(TYR1)

OPA:	HPODL_00442

YLI:	2909038(YALI2_F00624g)

SLB:	AWJ20_4481(TYR1)

NCR:

NCU00468

NTE:	NEUTE1DRAFT63778(NEUTE1DRAFT_63778)

SMP:	10806339(SMAC4_01902)

PAN:	PODANSg5004

PBEL:

QC761_706130(TYR1)

PPSD:

QC762_0108520(TYR1_1)

PPSP:

QC763_0104910(TYR1_1)

PPSA:

QC764_0114340(TYR1_1)

TTT:	THITE_2119199

MTM:	MYCTH_2304552

CTHR:

CTHT_0027030

MGR:

MGG_05276

PGRI:

PgNI_09441

TMN:	UCRPA7_3870

SSCK:

SPSK_07157

FGR:	FGSG_04139

FPU:	FPSE_00159

FPOA:

FPOAC1_006586

FVN:	FVRRES_07199

FVR:	FVEG_16783

FOX:	FOXG_11498

NHE:	NECHADRAFT_62071

FFC:	NCS54_00834000

FKR:	NCS57_00877200

FMU:	J7337_011598

TRE:	TRIREDRAFT_46545

TRR:	M419DRAFT_140653

TATV:

25776447(TrAtP1_009477)

TASP:

36616964(TrAFT101_011637)

MAW:	19245977(TYR1)

MAJ:

MAA_02500

MBRN:

26240104(G6M90_00g042010)

PCHM:

VFPPC_08224

CMT:

CCM_09467

AMUS:

LMH87_010820

PLJ:	28884488(PLICBS_005742)

PTKZ:

JDV02_003621(TYR1)

VAL:	VDBG_06623

VDA:	VDAG_05675

CFJ:	CFIO01_12153

CLUP:

CLUP02_02649

CHIG:

CH63R_02006

SAPO:

SAPIO_CDS2121

ELA:	UCREL1_2152

PFY:	PFICI_02790

SSL:	SS1G_00089

BFU:	BCIN_03g06980(Bctyr1)

MBE:

MBM_07073

PSCO:

LY89DRAFT_688908

GLZ:	GLAREA_06907

ANI:	ANIA_05959

AFM:	AFUA_2G10450

ACT:	ACLA_069470

NFI:	NFIA_085830

AOR:	AO090011000595

ANG:	An02g06120

AFV:	AFLA_007992

ALUC:

AKAW2_21119S(TYR1)

ACHE:

ACHE_40124S(TYR1)

APUU:

APUU_10998S(TYR1)

PCS:	N7525_004303

PDP:	PDIP_64170

POU:	POX_f07938

TMF:	EYB26_003500

TRG:	TRUGW13939_07821

CIM:	CIMG_04349

CPW:	CPC735_073810

URE:	UREG_01596

ABE:

ARB_05782

TVE:

TRV_04459

PBL:	PAAG_01432

PBN:	PADG_00336

AJE:	HCAG_08076

BGH:	BDBG_07095

PNO:	SNOG_02089

PTE:

PTT_08159

PTRR:

6346513(PtrM4_150340)

BZE:	COCCADRAFT_8140

BSC:	COCSADRAFT_29078

BOR:	COCMIDRAFT_32343

AALT:

CC77DRAFT_1017399

ARAB:

EKO05_0004623

ZTR:	MYCGRDRAFT_108107

PFJ:	MYCFIDRAFT_65373

FFU:	CLAFUR5_10453

CBET:

CB0940_06317

BCOM:

BAUCODRAFT_37685

NPA:	UCRNP2_3357

TML:	GSTUM_00004491001

SPO:	2539274(tyr1)

SOM:	SOMG_04098(tyr1)

CNE:

CNK03330

CNB:

CNBK0170

CNG:	CNAG_01997

CGI:	CGB_K0270C

CDEU:

CNBG_2957

CDEP:

91089529(L203_105320)

KMG:	30161465(I203_105841)

KNE:	92183273(IAR55_006015)

TMS:	TREMEDRAFT_44851

TASA:

A1Q1_03504

CCAC:

CcaHIS019_0302850(TYR1)

TVS:	TRAVEDRAFT_57752

PCO:	PHACADRAFT_255707

SHS:	STEHIDRAFT_121179

HIR:	HETIRDRAFT_327551

PSQ:	PUNSTDRAFT_66867

ADL:	AURDEDRAFT_116964

FME:	FOMMEDRAFT_149722

GTR:	GLOTRDRAFT_75626

RSX:	RhiXN_04878

LBC:	LACBIDRAFT_248404

CCI:	CC1G_15508

ABP:	AGABI1DRAFT122388(AGABI1DRAFT_122388)

ABV:	AGABI2DRAFT226049(AGABI2DRAFT_226049)

PCUB:

JR316_0012796 JR316_0012800

MRR:	Moror_1240

E1B28_000324

SCM:	SCHCO_02631237(SCHCODRAFT_02631237)

CPUT:

CONPUDRAFT_126641

SLA:	SERLADRAFT_477354

WSE:	WALSEDRAFT_59058

WIC:	J056_004521

UMA:	UMAG_04182

PFP:	PFL1_06707

SGRA:

EX895_001633

MGL:	MGL_4145 MGL_4163

MRT:

MRET_0865

MSYM:

MSY001_2937

PGR:	PGTG_02942

PTRC:

PtA15_14A113 PtA15_1A118

PSTR:

Pst134EA_013834

MLR:	MELLADRAFT_41385

RIE:	OCT59_023106

PEP:	AQ505_14455

PCM:	AY601_3124

PSTY:

BFS30_23235

PEJ:	FYC62_00250

PEK:	FFJ24_017580

PROE:

H9L23_18290

PEX:	IZT61_09285

PMUO:

LOK61_14095

PGJ:	QG516_01290

PSN:	Pedsa_2150

MUP:	A0256_09280

MUC:

MuYL_4319

MGOT:

MgSA37_01016(tyrA)

MUH:	HYN43_028020

MGIN:

FRZ54_23305

MGK:	FSB76_07250

MRUB:

DEO27_029785

MGOS:

DIU38_031965

MMAB:

HQ865_17910

MGIK:

GO620_010080

MJJ:	PQO05_03555

MSAB:

SNE25_28890

SBX:	CA265_16955

LBY:

Lbys_1216

EOL:	Emtol_3875

EMZ:	MB380_09485

ALS:	DJ013_09550

» show all

Reference

1 [PMID:4379953]

Authors

Gamborg OL, Keeley FW.

Title

Aromatic metabolism in plants. I. A study of the prephenate dehydrogenase from bean plants.

Journal

Biochim Biophys Acta 115:65-72 (1966)
DOI:10.1016/0304-4165(66)90049-3

Other DBs

ExplorEnz - The Enzyme Database:

1.3.1.13

IUBMB Enzyme Nomenclature:

1.3.1.13

ExPASy - ENZYME nomenclature database:

1.3.1.13

BRENDA, the Enzyme Database:

1.3.1.13

CAS:	37251-11-9

DBGET integrated database retrieval system