KEGG   ENZYME: 1.3.1.19Help
Entry
EC 1.3.1.19                 Enzyme                                 

Name
cis-1,2-dihydrobenzene-1,2-diol dehydrogenase;
cis-benzene glycol dehydrogenase;
cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase
Reaction(IUBMB)
cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+ [RN:R00812]
Reaction(KEGG)
Substrate
cis-1,2-dihydrobenzene-1,2-diol [CPD:C04091];
NAD+ [CPD:C00003]
Product
catechol [CPD:C00090];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.3.1.19 created 1972
Pathway
ec00361  Chlorocyclohexane and chlorobenzene degradation
ec00362  Benzoate degradation
ec00623  Toluene degradation
ec00624  Polycyclic aromatic hydrocarbon degradation
ec00643  Styrene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16269  cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
Genes
PPF: Pput_2877
PPX: T1E_4270(tobD)
PMON: X969_10950
PMOT: X970_10605
BPT: Bpet3742(hcaB)
Taxonomy
Reference
1  [PMID:4362337]
  Authors
Axcell BC, Geary PJ.
  Title
The metabolism of benzene by bacteria. Purification and some properties of the enzyme cis-1,2-dihydroxycyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase (cis-benzene glycol dehydrogenase).
  Journal
Biochem J 136:927-34 (1973)
Reference
2  [PMID:4298226]
  Authors
Gibson DT, Koch JR, Kallio RE.
  Title
Oxidative degradation of aromatic hydrocarbons by microorganisms. I. Enzymatic formation of catechol from benzene.
  Journal
Biochemistry 7:2653-62 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.19
IUBMB Enzyme Nomenclature: 1.3.1.19
ExPASy - ENZYME nomenclature database: 1.3.1.19
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.19
BRENDA, the Enzyme Database: 1.3.1.19
CAS: 51923-03-6

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