KEGG   ENZYME: 1.3.1.20
Entry
EC 1.3.1.20                 Enzyme                                 
Name
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;
dihydrodiol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase
Reaction(IUBMB)
trans-1,2-dihydrobenzene-1,2-diol + NADP+ = catechol + NADPH + H+ [RN:R00814]
Reaction(KEGG)
R00814;
(other) R07015 R09420
Substrate
trans-1,2-dihydrobenzene-1,2-diol [CPD:C04221];
NADP+ [CPD:C00006]
Product
catechol [CPD:C00090];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.3.1.20 created 1972
Pathway
ec00980  Metabolism of xenobiotics by cytochrome P450
Orthology
K00078  dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP)
K00212  20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase
Genes
HSA1645(AKR1C1) 27294(DHDH)
PTR100607996 456194(DHDH)
PPS100986729 100991467(DHDH)
GGO101146324 101152398(DHDH) 115936027
PON100171658(AKR1C1) 100174691(DHDH) 100189776
NLE100591778(DHDH) 100605934
MCC711198(AKR1C1) 711360(AKR1C2) 718930(DHDH)
MCF101865536(AKR1C1) 102133381(DHDH) 102141103
MTHB126943591 126963006 126963009
CSAB103235003(DHDH) 103237807 103237808
CATY105587685 105587688 105595264(DHDH)
PANU101023297
TGE112613019(DHDH) 112631308 112631309
RRO104666542(DHDH) 104678925
RBB108523635(DHDH) 108532991 108532992
TFN117083548 117083560 117087703 117087714 117091536(DHDH)
CANG105514879(DHDH) 105521701 105521702
CJC100390604(DHDH) 100404656(AKR1C1)
SBQ101042532 101049549(DHDH)
CSYR103253612(DHDH)
MMUR105865597(DHDH)
LCAT123623847(DHDH)
PCOQ105809317(DHDH)
OGA100957809(DHDH)
MMU71755(Dhdh)
MCAL110298665(Dhdh) 110308710
MPAH110315750 110337709(Dhdh)
RNO307092(Akr1c1) 691002(Dhdh)
MCOC116102207(Dhdh)
MUN110540624(Dhdh) 110540933 110542801
CGE100753544(Dhdh) 100770100
MAUA101825360(Dhdh)
PLEU114684644(Dhdh) 114708030
MORG121449119(Dhdh)
MFOT126488047
AAMP119802473(Dhdh)
NGI103725895 103743638(Dhdh)
HGL101713222(Dhdh) 101716553
CPOC100722094 100724342 100724620 100731362(Dhdh)
CCAN109680485 109682683(Dhdh)
DSP122125839(Dhdh)
NCAR124966988
OCU100008610(DHDH) 100348607(PGER1) 100352716
OPI101525116 101525279 101526245 101528513(DHDH) 118759111
TUP102470508(DHDH)
GVR103587761(DHDH)
CFA403786(DHDH)
CLUD112645180(DHDH)
VVP112931391(DHDH)
VLG121475970(DHDH)
AML100477136(DHDH)
UMR103657108(DHDH)
UAH113243321(DHDH)
UAR123776227(DHDH)
ELK111160798
LLV125088967
MPUF101686519(DHDH)
ORO101371357(DHDH)
EJU114199626(DHDH)
ZCA113935676(DHDH)
MLX117998244(DHDH)
NSU110572853(DHDH)
LWW102751176(DHDH)
FCA101101272(DHDH)
PYU121018750(DHDH)
PBG122494845(DHDH)
LRUF124510926
PTG102948867(DHDH)
PPAD109253091(DHDH)
AJU106988698(DHDH)
HHV120240202(DHDH)
BTA617564(DHDH)
BOM102280401(DHDH)
BIU109572213(DHDH)
BBUB102399742(DHDH)
BBIS104995632(DHDH)
CHX102188075(DHDH)
OAS101103175(DHDH)
ODA120872168(DHDH)
CCAD122421034(DHDH)
SSC397337(DHDH)
CFR102512639(DHDH)
CBAI105062610(DHDH)
CDK105102891(DHDH)
VPC102544148(DHDH)
BACU103008204(DHDH)
ECB100051521(DHDH) 100070570
EPZ103540778 103553311(DHDH)
EAI106827244 106838267(DHDH)
MYB102262437(DHDH)
MYD102770117(DHDH)
MMYO118655427(DHDH)
MLF102443300(DHDH)
MNA107531900(DHDH)
PKL118712170(DHDH)
HAI109391066(DHDH)
DRO112310193(DHDH)
AJM119036829(DHDH)
PDIC114511061(DHDH)
PHAS123830278(DHDH)
MMF118639275(DHDH)
RFQ117034547(DHDH)
PALE102885391(DHDH)
PGIG120606955(DHDH)
PVP105301763(DHDH)
RAY107498830(DHDH)
MJV108400314(DHDH)
TOD119249543(DHDH)
SARA101540687(DHDH)
LAV100660549(DHDH)
TMU101355202
ETF101646389(DHDH)
DNM101433194(DHDH) 101433871 101435315
MDO100030403(DHDH)
GAS123242890(DHDH) 123247018 123248678
SHR111720213(DHDH)
PCW110220115(DHDH)
GGA777348(DHDH)
PCOC116240033(DHDH)
MGP104916162(DHDH)
CJO107325868(DHDH)
NMEL110390997(DHDH)
TGU115491770(DHDH)
LSR110481421(DHDH)
OTC121332636
PHI102104923(DHDH)
PMAJ107199051(DHDH)
AGEN126034868
ASN102376323(DHDH)
AMJ102574630(DHDH)
CPOO109320820(DHDH)
PSS102447655(DHDH)
CMY102931206(DHDH)
CPIC101949641 101952305
TST117888429(DHDH)
CABI116840048 116840080(DHDH)
MRV120388323 120388324
ACS100560732 100560929 100561324 100562900
PVT110078474 110078540 110078568
SUND121933340 121933341 121933342 121933344
PBI103054661 103055457
PMUR107282543(DHDH)
CTIG120304524(DHDH)
TSR106538690(DHDH)
PGUT117669108(DHDH)
VKO123032094 123032205 123032207
PMUA114582606 114582681 114582780
ZVI118094926 118095810 118095891
GJA107116584 107116602 107116603
XLA108697264 444539(dhdh-like.1.L)
XTR100145807(dhdh) 448579(dhdh)
NPR108800662 108800663
RTEM120915346(DHDH)
BBUF121001904 121001919
BGAR122926720 122928638
DRE406433(dhdh.1) 449558(dhdh.2)
SRX107709394 107712874 107713116
SANH107665090 107665427 107665437 107668471
SGH107553352 107595342(dhdh)
CCAR109063738(dhdh) 109075356
CAUA113061390 113061391 113090243 113118075 113118076
PPRM120487591(dhdh.1) 120487595(dhdh.2)
MAMB125254692(dhdh.1) 125254746(dhdh.2)
IPU100528487(dhdh.2) 124627896
PHYP113526400(dhdh)
SMEO124395663(dhdh.2)
TFD113650768(dhdh.2)
AMEX103043227 103045107 103045417
EEE113576071
TRU101067668 101068481 101068704
TNGGSTEN00000746G001 GSTEN00012065G001
LCO109139643 109142654
NCC104959258 104962854
CGOB115025328
ELY117251231(dhdh.2) 117257557
EFO125899300(dhdh.2) 125899307(dhdh.1) 125899715
PLEP121944994(dhdh.2) 121945624(dhdh.1) 121949449
SLUC116037533(dhdh.2)
ECRA117942893(dhdh.2)
ESP116689862
PFLV114557526
GAT120831814(dhdh.2) 120834169
PPUG119226428(dhdh.2)
MSAM119889802(dhdh.2)
CUD121513714 121522252 121523339(dhdh.2)
ALAT119017704 119017706 119018266 119026305
MZE101466663
ONL100699617(dhdh) 100709652 109202511
OAU116325505 116325587(dhdh.2)
OLA101161387 101170260
OML112160989 112160990
XMA102230657 102231180 102231435
XCO114142662 114143656 114143657
XHE116718058 116718060 116718061 116718062
PRET103462676 103462677 103462679 103462745
PFOR103154711(dhdh)
PLAI106961720
PMEI106913099 106913443 106922157 106922160
GAF122819685 122819690 122819711
CVG107095320 107095329
CTUL119795117 119795140 119795142(dhdh.1)
GMU124866773 124867185
NFU107381267(dhdh) 107381268
KMR108240245 108240257 108240258
ALIM106529988 106530000
NWH119430127 119430128
AOCE111567618 111571639 111571640 111571659
MCEP125005267 125005268 125005446 125005592
CSEM103378996 103378997
POV109624939 109625014
SSEN122772624 122772831
HHIP117757207 117759290(dhdh.2)
HSP118105178(dhdh.2) 118110304(dhdh.1)
LCF108876877 108876962
SDU111218641 111221353 111222353
SLAL111649505 111649507 111671508
XGL120794833(dhdh.1) 120801532
HCQ109513915 109513916
BPEC110156372 110175360 110175496
MALB109955837(dhdh)
BSPL114851776 114851777 114852232 114852789
SASA100196772(dhdh) 106586438 106587215
STRU115160969 115167315 115167316
OTW112235746 112235761 112238788 112264191
OMY110520289 110526353 110526354(dhdh.2)
OGO124033798 124042941
ONE115112200 115112529 115115747
SALP111969572 111974720 111974721 111977378
SNH120025366 120036864 120036866 120057905
CCLU121536318 121582302(dhdh.2)
ELS105015657 105015822
SFM108930140
PKI111847990(dhdh)
AANG118227383(dhdh.2) 118227384 118227424
LOC102692599(dhdh)
PSPA121294381
ARUT117429242 117963168
LCM102353287(DHDH)
CMK103189533
RTP109916392(dhdh)
BFO118407083
BBEL109467398 109467399 109467407 109473215 109473367 109482310
CIN100186038
SCLV120333416 120333425
SPU100891256 581125 581189 583996 588939
APLC110979612 110982584 110989501
AJC117111555
SKO100369547 100369697
DMEDmel_CG13280(CG13280) Dmel_CG3597(CG3597) Dmel_CG3609(CG3609)
DER6541366 6541604 6547628
DSE6613087 6613088 6614431
DSIDsimw501_GD11964(Dsim_GD11964) Dsimw501_GD22839(Dsim_GD22839) Dsimw501_GD22840(Dsim_GD22840)
DYADyak_GE13162 Dyak_GE15118 Dyak_GE15120
DAN6498091 6498092
DSR110184938 110187287 110187308
DPO4816794 4817398 4817478
DPE6589241 6589434 6589435
DMN108161945 108162652 108163513
DWI6641896 6641897 6643528 6644481
DGR6566603 6566604
DMODmoj_GI17180 Dmoj_GI17186 Dmoj_GI17187
DAZ108609472 108611285 108620500
DNV108657724 115562357 115562360
DHE111595497 111595504 111601181
DVI6628921 6628922
CCAT101459973 101460501 105664445
BOD106627582 106627594 106627595
RZE108353932 108363144 108363146
MDE101900891
SCAC106086127
LCQ111676409
LSQ119610927
HIS119651323 119651324
AGAAgaP_AGAP009225 AgaP_AGAP009945
ACOZ120955603 120958717
AARA120902304 120903729
ASTE118512038 118512580
AAG5572674 5575161
AALB109398262 109419782 109420591 115255013
CQUCpipJ_CPIJ000841 CpipJ_CPIJ014580
CPII120413507 120418645
CNS116338110 116338203 116341595
BCOO119073281 119075711 119076382 119077405 119078292 119078293 119079754
AME412231
ACER107997386
ALAB122714576
BIM100740559
BBIF117213213
BVK117239503
BVAN117162323
BTER100649548
BPYO122572759
CCAL108630663
OBB114873113
MGEN117218725
NMEA116431184
CGIG122403662
SOC105208047
MPHA105835107
AEC105154186
ACEP105622679
PBAR105434330 105434331
VEM105560923
HST105186645
DQU106741522
CFO105257164 105257165
FEX115237753
LHU105671479
PGC109857477
OBO105284215
PCF106785709
PFUC122519681
VPS122630470
NVI100117805
TPRE106654210
MDL103578346
CGLO123267783
FAS105266916
DAM107036954
AGIF122854301
CINS118068153
LHT122499025
CCIN107264585
TCA660272 661259
DPA109533561 109534808
SOY115888187
ATD109599316 109599317 109599880 109607163 109607176
CSET123311907
AGB108912205 108912881
LDC111509371 111515227
NVL108560837
APLN108733592 108742036
PPYR116159525 116160058 116160693
OTU111428478
BMOR101739041 101744141
BMAN114246311 114252054
MSEX115443738 115448674 119188489
DPLKGM_215754 KGM_215781
BANY112044257 112052102 112052103
NIQ126772379 126772641 126781878
PMAC106709317 106717577
PPOT106099353 106100802
PXU106124758 106124877
PRAP111003825 111003869
PBX123715934 123716313 123716601
PNAP125054461
ZCE119829552 119829704
CCRC123697221 123700518 123701785
HAW110377761 110377790 110378531
HZE124633408 124634935 124635327
TNL113496171 113501943 113502165
SLIU111352846 111352965 111353256 111356690
OFU114351674 114351913 114357580
PXY105391648 105396722
API100160235 100162948
DNX107164951 107165480
AGS114122663 114122664 114131068
RMD113548345
HHAL106677376 106679661 106685476 106685484
FOC113202165 113211244
TPAL117645221 117653083
ZNE110838823
CSEC111873256
SGRE126268231 126281694 126282002
FCD110848466 110851368 110851432 110853947 110861155
PVM113811513 113819808
PJA122266417 122266420 122267624
PCHN125024952 125048036
HAME121862129
PCLA123746909 123746911 123746912
PTRU123506622 123506623 123511170
HAZT108682626
EAF111709298
LSM121117352 121117435
PPOI119111046
ISCIscW_ISCW009997
DSV119455607 119456492
RSAN119393955 119394807
VDE111250781
VJA111268866
TUT107361962 107371141
CSCU111640181
PTEP107439493 107455902 107456420 122268241
SDM118197191
HROHELRODRAFT_74868
LGILOTGIDRAFT_208067
PCAN112559213 112560362 112560510
GAE121368040 121368041 121368042
HRF124113678 124113682 124113684 124142983
HRJ124267593 124284299
CRG105323672
MYI110455909
PMAX117339534
MMER123535820 123536383 123536673 123555126 123555691
OBI106867507 106872773 106873778 106873779 106873780 106877994
OSN115218237 115218278 115218279 115218305 115218360 115218450 115218668
LAK106160733 106174125 106174127 106174128 106181072
NVE5505671
EPA110244148
ATEN116289093
ADF107341873
AMIL114975326
PDAM113683557
SPIS111325722
DGT114517734
XEN124453659
HMG100207079 100210586
AQU100640874 100640997
QSU112002984 112040336
SPAASPAPADRAFT_60972
CTPCTRG_01154
COTCORT_0A12250
CDUCD36_15820
TMNUCRPA7_3182
FGRFGSG_03001 FGSG_11142
FPUFPSE_02237 FPSE_02878
FVRFVEG_12356
NHENECHADRAFT_101044
VALVDBG_02693
PFYPFICI_02658
AORAO090011000704
TMFPMAA_029160
PNOSNOG_03900
PTEPTT_14440
BZECOCCADRAFT_3352
BSCCOCSADRAFT_183098
BORCOCMIDRAFT_26095
AALTCC77DRAFT_1019834
PFJMYCFIDRAFT_184262
BCOMBAUCODRAFT_264297
NPAUCRNP2_9163
CNECNE04820
CNBCNBE4820
CNGCNAG_02052
CGICGB_E6390C
SMINv1.2.018378.t1(symbB.v1.2.018378.t1)
PTIPHATRDRAFT_25422
FCYFRACYDRAFT_168694
TPSTHAPSDRAFT_23184 THAPSDRAFT_36572
AAFAURANDRAFT_18834 AURANDRAFT_20106 AURANDRAFT_72519
PIFPITG_14355 PITG_14356 PITG_14357 PITG_14358 PITG_18534 PITG_18535 PITG_18536 PITG_18537
PSOJPHYSODRAFT_327667 PHYSODRAFT_327668 PHYSODRAFT_496155
SPARSPRG_05860
EHXEMIHUDRAFT_435339 EMIHUDRAFT_436368
NGRNAEGRDRAFT_56213
AHAAHA_2098
AHYAHML_12515
AHDAI20_07520
AHRV428_12915
AHPV429_12935
AHJV469_10130
AHHRY45_12335
AHIVU14_09895
AAJBOQ57_12145
ASAASA_2199
AEOO23A_p1257
AMEDB224_2088
ADHCK627_14270
AEAC2U39_10065
ARVC7N77_14940
AESC2U30_03610
AELNCTC12917_01967(afr)
ASIMFE240_07335
PPYPPE_00921
PPOLX809_04420
PTAHPL003_12505
PPEOABE82_04575
PKBB4V02_20495
MAURBOH66_03565
MOOBWL13_00475(afr_3)
 » show all
Reference
1  [PMID:13651190]
  Authors
AYENGAR PK, HAYAISHI O, NAKAJIMA M, TOMIDA I.
  Title
Enzymic aromatization of 3,5-cyclohexadiene-1,2-diol.
  Journal
Biochim Biophys Acta 33:111-9 (1959)
DOI:10.1016/0006-3002(59)90504-9
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.20
IUBMB Enzyme Nomenclature: 1.3.1.20
ExPASy - ENZYME nomenclature database: 1.3.1.20
BRENDA, the Enzyme Database: 1.3.1.20
CAS: 37255-32-6

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