KEGG   ENZYME: 1.3.1.24Help
Entry
EC 1.3.1.24                 Enzyme                                 

Name
biliverdin reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
bilirubin:NAD(P)+ oxidoreductase
Reaction(IUBMB)
bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+ [RN:R02391 R02393]
Reaction(KEGG)
Substrate
bilirubin [CPD:C00486];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
biliverdin [CPD:C00500];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.3.1.24 created 1972
Pathway
ec00860  Porphyrin and chlorophyll metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00214  biliverdin reductase
K05901  biliverdin reductase / flavin reductase
Genes
HSA: 644(BLVRA) 645(BLVRB)
PTR: 456039(BLVRB) 463366(BLVRA)
PPS: 100976517(BLVRA) 100989093(BLVRB)
GGO: 101142015(BLVRB) 101145695(BLVRA)
PON: 100434664(BLVRA) 100446184(BLVRB)
NLE: 100581836(BLVRA) 100587172(BLVRB)
MCC: 700980(BLVRA) 703020(BLVRB)
MCF: 102136439(BLVRA) 102142962(BLVRB)
CSAB: 103226154(BLVRA) 103234707(BLVRB)
RRO: 104676113(BLVRB) 104676702(BLVRA)
RBB: 108539085(BLVRB) 108544019(BLVRA)
CJC: 100391206(BLVRB) 100404177(BLVRA)
SBQ: 101043206(BLVRB) 101051509(BLVRA)
MMU: 109778(Blvra) 233016(Blvrb)
RNO: 116599(Blvra) 292737(Blvrb)
CGE: 100751522(Blvra) 100768929(Blvrb)
NGI: 103733050(Blvra) 103750766(Blvrb)
HGL: 101697384(Blvrb) 101722954(Blvra)
CCAN: 109682461(Blvra) 109688540(Blvrb)
OCU: 100340115(BLVRB) 100346798(BLVRA)
TUP: 102476728(BLVRA) 102490802(BLVRB)
CFA: 475867(BLVRA) 476456(BLVRB)
AML: 100467254(BLVRB) 100474311(BLVRA)
UMR: 103661047(BLVRB) 103674578(BLVRA)
ORO: 101371765(BLVRB) 101385773(BLVRA)
FCA: 101088735(BLVRA) 101092315(BLVRB)
PTG: 102957548(BLVRA) 102957700(BLVRB)
AJU: 106977737(BLVRA) 106979604(BLVRB)
BTA: 281650(BLVRB) 504596(BLVRA)
BOM: 102277747(BLVRB) 102279089(BLVRA)
BIU: 109557549(BLVRA) 109572681(BLVRB)
PHD: 102331348 102344863(BLVRA)
CHX: 102186555(BLVRA) 102187796(BLVRB)
OAS: 101118353(BLVRA) 101119750(BLVRB)
SSC: 100515289(BLVRA) 100625219(BLVRB)
CFR: 102503539(BLVRA) 102522968(BLVRB)
CDK: 105092327(BLVRA) 105093394(BLVRB)
BACU: 103006819(BLVRA) 103014515(BLVRB)
LVE: 103073162(BLVRA) 103082225(BLVRB)
OOR: 101269881(BLVRB) 101285825(BLVRA)
ECB: 100064761(BLVRA) 100068145(BLVRB)
EPZ: 103555616(BLVRA) 103560493(BLVRB)
EAI: 106839159(BLVRA) 106843297(BLVRB)
MYB: 102243524(BLVRA) 102251416(BLVRB)
MYD: 102759928(BLVRB) 102775325(BLVRA)
HAI: 109374869(BLVRB) 109375451(BLVRA)
RSS: 109438807(BLVRA) 109458110(BLVRB)
PALE: 102879551(BLVRB) 102892087(BLVRA)
LAV: 100660266(BLVRA) 100665167(BLVRB)
MDO: 100017892(BLVRB) 100029544(BLVRA)
SHR: 100915926(BLVRA) 100930351(BLVRB)
OAA: 100073853(BLVRB) 100076047(BLVRA) 100681226
GGA: 420776(BLVRA)
MGP: 100303679(BLVRB) 100542635(BLVRA)
CJO: 107309812(BLVRA)
APLA: 101793149(BLVRA)
ACYG: 106042895(BLVRA)
TGU: 100224786(BLVRA) 100231163
GFR: 102043974(BLVRA)
FAB: 101818701(BLVRA)
PHI: 102102005(BLVRA) 102113532(BLVRB)
PMAJ: 107200264(BLVRA)
CCW: 104688918(BLVRA)
FPG: 101924606(BLVRA)
FCH: 102055391(BLVRA)
CLV: 102097224(BLVRA) 110356600(BLVRB)
EGZ: 104125204(BLVRA)
AAM: 106493723(BLVRB) 106495280(BLVRA)
ASN: 102371445(BLVRA) 102387963(BLVRB)
AMJ: 102567480(BLVRA) 102574563(BLVRB)
PSS: 102463244(BLVRA)
CMY: 102933712(BLVRA)
CPIC: 101948417(BLVRB) 101950655(BLVRA)
ACS: 100564394(blvra) 100564796(blvrb)
PVT: 110075662(BLVRB) 110081583(BLVRA)
PBI: 103049956(BLVRA) 103053858(BLVRB)
GJA: 107107369(BLVRB) 107109993(BLVRA) 107123558
XLA: 100137674(blvra.L) 443881(blvrb.L)
XTR: 100124834(blvrb) 448743(blvra)
NPR: 108791950(BLVRB) 108797466(BLVRA)
DRE: 436959(blvrb) 767661(blvra)
SRX: 107713657(blvra) 107717620(blvrb) 107757787
SGH: 107599292 107600218(blvra) 107602119(blvrb)
IPU: 100528810(blvra) 108264654(blvrb)
AMEX: 103037727(blvra) 103040962(blvrb)
TRU: 101061122(blvrb) 101070243(blvra)
LCO: 104927805(blvrb) 104930153(blvra) 109140017
NCC: 104965039(blvrb)
MZE: 101473603(blvra) 101484658(blvrb)
OLA: 101163919(blvrb) 101175193(blvra)
XMA: 102228591(blvrb) 102229366(blvra)
PRET: 103475161(blvrb) 103479218(blvra)
NFU: 107379787(blvrb) 107384337(blvra)
CSEM: 103377891(blvrb)
HCQ: 109515486(blvra) 109529422(blvrb)
BPEC: 110168032(blvra) 110172712(blvrb)
SASA: 106569211(blvra) 106580739(blvrb) 106599287 106612705(BLVRB)
ELS: 105023068(blvrb) 105024256(blvra)
SFM: 108928749(blvrb) 108934031(blvra)
LCM: 102358034(BLVRB)
CMK: 103173572(blvrb) 103181265(blvra)
CIN: 100185152
DSI: Dsimw501_GD20759(Dsim_GD20759)
MDE: 101892800
AAG: 5565330
BIM: 100749252
BTER: 100646178
AEC: 105144797
ACEP: 105624072
PBAR: 105426660
CFO: 105252649
LHU: 105674651
PGC: 109861802
NVI: 100113525
TCA: 664311
DPA: 109534878
NVL: 108556546
BMOR: 101736226
PMAC: 106708927
PRAP: 111001233
PXY: 105393340
API: 100168586(Blvrb) 100574136
DNX: 107162985
ZNE: 110828593
CRG: 105324708
MYI: 110447723
OBI: 106880542
EPA: 110249688
ADF: 107348181
SYN: slr1784(bvdR)
SYZ: MYO_12210(bvdR)
SYY: SYNGTS_0221(bvdR)
SYT: SYNGTI_0221(bvdR)
SYS: SYNPCCN_0221(bvdR)
SYQ: SYNPCCP_0221(bvdR)
SYJ: D082_05120(bvdR)
SYP: SYNPCC7002_A2324(bvdR)
CYA: CYA_2461
CYB: CYB_1431
LET: O77CONTIG1_00600(ydgJ)
HHG: XM38_017200(ydgJ)
MAR: MAE_61890(bvdR)
MPK: VL20_2197
CYL: AA637_13445(bvdR)
CYT: cce_1608(bvdR)
TER: Tery_0913
ARP: NIES39_B00110(bvdR)
GVI: gvip105(bvdR)
GLJ: GKIL_1362(bvdR)
ANA: alr4149(bvdR)
AVA: Ava_0755
NAZ: Aazo_0182
CALH: IJ00_21030
CTHE: Chro_2639
CEO: ETSB_0923(bvdR)
 » show all
Taxonomy
Reference
1  [PMID:4378982]
  Authors
Singleton JW, Laster L.
  Title
Biliverdin reductase of guinea pig liver.
  Journal
J Biol Chem 240:4780-9 (1965)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.24
IUBMB Enzyme Nomenclature: 1.3.1.24
ExPASy - ENZYME nomenclature database: 1.3.1.24
BRENDA, the Enzyme Database: 1.3.1.24
CAS: 9074-10-6

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