Entry
Name
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase;
dihydrodihydroxybenzoate dehydrogenase;
DHBDH;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase;
2-hydro-1,2-dihydroxybenzoate dehydrogenase;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase;
dihydrodihydroxybenzoate dehydrogenase;
(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)
Reaction(IUBMB)
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+ [RN:
R00813 ]
Reaction(KEGG)
Substrate
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate [CPD:
C06321 ];
NAD+ [CPD:
C00003 ]
Product
History
EC 1.3.1.25 created 1976, modified 2004 (EC 1.3.1.55 created 1999, incorporated 2004)
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K05783 dihydroxycyclohexadiene carboxylate dehydrogenase
Genes
RTG : NCTC13098_03815(lvr_2)
SFJ : SAMEA4384070_3090(xecD)
VIB : VspSTUT11_38640(benD)
PFUW : KF707C_15520(bzaB) KF707C_28440
PAEB : NCGM1900_4012(benD)
PNT : G5B91_12950 G5B91_33240
PPUN : PP4_25400(benD) PP4_48180(benD)
PPRC : PFLCHA0_c39130(xylL)
PFO : Pfl01_2324 Pfl01_2965(benD)
PMUD : NCTC8068_02088(xylL)
PPUU : PputUW4_03254(xylL)
PTW : TUM18999_29750(xylL)
PTAE : NCTC10697_02700(benD)
PTRL : OU419_12615 OU419_14760
PALL : UYA_06695(benD) UYA_20405(benD)
HAAH : HALA3H3_1060003(benD)
RPJ : N234_27840 N234_37270(benD)
COX : E0W60_20505 E0W60_32235
BMN : BMA10247_A0212(benD)
BPM : BURPS1710b_A1002(benD)
BPL : BURPS1106A_A2584(benD)
BPD : BURPS668_A2728(benD)
BPZ : BP1026B_II2045(benD)
PARB : CJU94_35245(benD) CJU94_37920(benD)
PHS : C2L64_29825(benD) C2L64_48515(benD)
PGIS : I6I06_20450 I6I06_20465
PDIO : PDMSB3_2246.1(benD)
BTRM : SAMEA390648701944(benD)
THK : CCZ27_03210(benD) CCZ27_16240(benD)
THAG : CKCBHOJB_01554(lvr)
SFD : USDA257_c54420(benD)
AVF : RvVAR031_pl03340(benD)
RMM : ROSMUCSMR3_03736(lvr)
NPP : PP1Y_AT15839 PP1Y_AT31260
CCYS : SAMEA4530656_0415(benD)
RCR : NCTC10994_02858(benD)
ACRY : AC20117_04985(benD)
» show all
Taxonomy
Reference
Authors
Reiner AM.
Title
Metabolism of aromatic compounds in bacteria. Purification and properties of the catechol-forming enzyme, 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid (NAD + ) oxidoreductase (decarboxylating).
Journal
J Biol Chem 247:4960-5 (1972)
Reference
Authors
Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S
Title
cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.25
ExPASy - ENZYME nomenclature database: 1.3.1.25
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.25