Entry |
|
Name |
geissoschizine dehydrogenase
|
Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
geissoschizine:NADP+ 4,21-oxidoreductase
|
Reaction(IUBMB) |
geissoschizine + NADP+ = 4,21-didehydrogeissoschizine + NADPH [RN: R03860]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
4,21-didehydrogeissoschizine;
NADPH [CPD: C00005]
|
Comment |
Involved in the interconversion of heteroyohimbine alkaloids in Catharanthus roseus.
|
History |
EC 1.3.1.36 created 1986
|
Pathway |
ec00901 | Indole alkaloid biosynthesis |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
K23493 | geissoschizine synthase |
|
Reference |
1 |
Authors |
Pfitzner, A. and Stockigt, J. |
Title |
Partial-purification and characterization of geissoschizine dehydrogenase from suspension-cultures of Catharanthus roseus. |
Journal |
Phytochemistry 21:1585-1588 (1982) |
Other DBs |
ExplorEnz - The Enzyme Database: | 1.3.1.36 |
ExPASy - ENZYME nomenclature database: | 1.3.1.36 |
|