KEGG   ENZYME: 1.3.1.37
Entry
EC 1.3.1.37                 Enzyme                                 

Name
cis-2-enoyl-CoA reductase (NADPH);
NADPH-dependent cis-enoyl-CoA reductase;
reductase, cis-2-enoyl coenzyme A;
cis-2-enoyl-coenzyme A reductase;
cis-2-enoyl-CoA reductase (NADPH)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
acyl-CoA:NADP+ cis-2-oxidoreductase
Reaction(IUBMB)
acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH + H+ [RN:R00387]
Reaction(KEGG)
R00387
Substrate
acyl-CoA [CPD:C00040];
NADP+ [CPD:C00006]
Product
cis-2,3-dehydroacyl-CoA [CPD:C01122];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Not identical with EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH) [cf. EC 1.3.1.8 acyl-CoA dehydrogenase (NADP+)].
History
EC 1.3.1.37 created 1986
Reference
1  [PMID:6759504]
  Authors
Mizugaki M, Nishimaki T, Shiraishi T, Kawaguchi A, Okuda S, Yamanaka H.
  Title
Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli.
  Journal
J Biochem (Tokyo) 92:1649-54 (1982)
DOI:10.1093/oxfordjournals.jbchem.a134091
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.37
IUBMB Enzyme Nomenclature: 1.3.1.37
ExPASy - ENZYME nomenclature database: 1.3.1.37
BRENDA, the Enzyme Database: 1.3.1.37
CAS: 72841-00-0

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