KEGG ENZYME: 1.3.1.56

ENZYME: 1.3.1.56

Entry

EC 1.3.1.56 Enzyme

Name

cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase;
2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase

Reaction(IUBMB)

cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+ [RN:R05239]

Reaction(KEGG)

R05239;
(other) R05241

Substrate

cis-3-phenylcyclohexa-3,5-diene-1,2-diol [CPD:C06589];
NAD+ [CPD:C00003]

Product

biphenyl-2,3-diol [CPD:C02526];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

Catalyses the second step in the biphenyl degradation pathway in bacteria.

History

EC 1.3.1.56 created 2000

Pathway

ec00621

Dioxin degradation

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K08690

cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase

Genes

PSD:

DSC_09350

BXE:	Bxe_C1192(bphB)

BXB:	DR64_8613(bphB)

PNA:

Pnap_4147

ACK:	C380_15940(bphB)

CTES:

O987_08240

PGV:	SL003B_4098

RHA:	RHA1_ro08054(bphB) RHA1_ro10126(bphB2)

ROP:	ROP_pROB02-01630(bnzB)

Reference

1 [PMID:8702262]

Authors

Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D.

Title

Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB).

Journal

Appl Environ Microbiol 62:2710-5 (1996)

Sequence

[ag:AAB18304]

Reference

2 [PMID:8048958]

Authors

Fukuda M, Yasukochi Y, Kikuchi Y, Nagata Y, Kimbara K, Horiuchi H, Takagi M, Yano K.

Title

Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls.

Journal

Biochem Biophys Res Commun 202:850-6 (1994)
DOI:10.1006/bbrc.1994.2008

Reference

3 [PMID:8344527]

Authors

Hofer B, Eltis LD, Dowling DN, Timmis KN.

Title

Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation.

Journal

Gene 130:47-55 (1993)
DOI:10.1016/0378-1119(93)90345-4

Sequence

[bxe:Bxe_C1192]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.1.56

IUBMB Enzyme Nomenclature:

1.3.1.56

ExPASy - ENZYME nomenclature database:

1.3.1.56

UM-BBD (Biocatalysis/Biodegradation Database):

1.3.1.56

BRENDA, the Enzyme Database:

1.3.1.56

DBGET integrated database retrieval system