KEGG   ENZYME: 1.3.1.56
Entry
EC 1.3.1.56                 Enzyme                                 

Name
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase;
2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase
Reaction(IUBMB)
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+ [RN:R05239]
Reaction(KEGG)
R05239;
(other) R05241
Substrate
cis-3-phenylcyclohexa-3,5-diene-1,2-diol [CPD:C06589];
NAD+ [CPD:C00003]
Product
biphenyl-2,3-diol [CPD:C02526];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Catalyses the second step in the biphenyl degradation pathway in bacteria.
History
EC 1.3.1.56 created 2000
Pathway
ec00621  Dioxin degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K08690  cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
Genes
PSD: DSC_09350
BXE: Bxe_C1192(bphB)
BXB: DR64_8613(bphB)
PNA: Pnap_4147
ACK: C380_15940(bphB)
CTES: O987_08240
PGV: SL003B_4098
RHA: RHA1_ro08054(bphB) RHA1_ro10126(bphB2)
ROP: ROP_pROB02-01630(bnzB)
Reference
1  [PMID:8702262]
  Authors
Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D
  Title
Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB).
  Journal
Appl Environ Microbiol 62:2710-5 (1996)
DOI:10.1128/AEM.62.8.2710-2715.1996
  Sequence
Reference
2  [PMID:8048958]
  Authors
Fukuda M, Yasukochi Y, Kikuchi Y, Nagata Y, Kimbara K, Horiuchi H, Takagi M, Yano K.
  Title
Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls.
  Journal
Biochem Biophys Res Commun 202:850-6 (1994)
DOI:10.1006/bbrc.1994.2008
Reference
3  [PMID:8344527]
  Authors
Hofer B, Eltis LD, Dowling DN, Timmis KN
  Title
Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation.
  Journal
Gene 130:47-55 (1993)
DOI:10.1016/0378-1119(93)90345-4
  Sequence
[bxe:Bxe_C1192]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.56
IUBMB Enzyme Nomenclature: 1.3.1.56
ExPASy - ENZYME nomenclature database: 1.3.1.56
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.56
BRENDA, the Enzyme Database: 1.3.1.56

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Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (11)   
Protein sequence (177)   
   UniProt (119)   
   SWISS-PROT (6)   
   RefSeq(pep) (39)   
   PDBSTR (12)   
   PMD (1)   
DNA sequence (171)   
   RefSeq(nuc) (74)   
   GenBank (54)   
   EMBL (43)   
3D Structure (6)   
   PDB (6)   
Protein domain (4)   
   InterPro (4)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (388)   

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