KEGG   ENZYME: 1.3.1.56
Entry
EC 1.3.1.56                 Enzyme                                 
Name
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase;
2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase
Reaction(IUBMB)
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+ [RN:R05239]
Reaction(KEGG)
R05239;
(other) R05241
Substrate
cis-3-phenylcyclohexa-3,5-diene-1,2-diol [CPD:C06589];
NAD+ [CPD:C00003]
Product
biphenyl-2,3-diol [CPD:C02526];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Catalyses the second step in the biphenyl degradation pathway in bacteria.
History
EC 1.3.1.56 created 2000
Pathway
ec00621  Dioxin degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K08690  cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
Genes
PSDDSC_09350
PFUWKF707C_16280(bphB)
PALLUYA_07075
PCAVD3880_02400
ABOUACBO_15320
FCEJN531_005645(hcaB)
BXEBxe_C1192(bphB)
BXBDR64_8613(bphB)
PNAPnap_4147
ACKC380_15940(bphB)
CTESO987_08240
PGVSL003B_4098
BACAFAY30_11685
BKOCKF48_07585
NDTL1999_23270(hcaB)
MMANMMAN_22960(hcaB)
MBRDMBRA_22550(hcaB)
RHARHA1_ro08054(bphB) RHA1_ro10126(bphB2)
ROPROP_pROB02-01630(bnzB)
ROZCBI38_14165
SSOII1A49_46005(hcaB)
GYUFE374_10380
AACDLWP59_27020(hcaB)
HAADMW046_15100
HLSKU306_03855(hcaB)
MEMJMJ1HA_1405
 » show all
Reference
1  [PMID:8702262]
  Authors
Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D
  Title
Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB).
  Journal
Appl Environ Microbiol 62:2710-5 (1996)
DOI:10.1128/AEM.62.8.2710-2715.1996
  Sequence
Reference
2  [PMID:8048958]
  Authors
Fukuda M, Yasukochi Y, Kikuchi Y, Nagata Y, Kimbara K, Horiuchi H, Takagi M, Yano K.
  Title
Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls.
  Journal
Biochem Biophys Res Commun 202:850-6 (1994)
DOI:10.1006/bbrc.1994.2008
Reference
3  [PMID:8344527]
  Authors
Hofer B, Eltis LD, Dowling DN, Timmis KN
  Title
Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation.
  Journal
Gene 130:47-55 (1993)
DOI:10.1016/0378-1119(93)90345-4
  Sequence
[bxe:Bxe_C1192]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.56
IUBMB Enzyme Nomenclature: 1.3.1.56
ExPASy - ENZYME nomenclature database: 1.3.1.56
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.56
BRENDA, the Enzyme Database: 1.3.1.56

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